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The map label for this gene is lolE [H]

Identifier: 220933159

GI number: 220933159

Start: 2546158

End: 2547393

Strand: Reverse

Name: lolE [H]

Synonym: Hore_23270

Alternate gene names: 220933159

Gene position: 2547393-2546158 (Counterclockwise)

Preceding gene: 220933160

Following gene: 220933158

Centisome position: 98.81

GC content: 44.17

Gene sequence:

>1236_bases
ATGTTTCTCGCTAAACTGGCATTTAAAAACCTGGTGCGCCACCGGAATCGAACCCTGATAACAGCAAGTATTATTGCAAT
TGCCATATTCTTTTTTCTTCTCCTTGATTCATTAATCGGCGGGATGACCGAAATGTCCTATGATACTATCATTAATTATG
AGGCCGGACATCTTCAACTTGCCCACCGGGAATACTGGGAGGAAGAGGAAGAACTGCCCCTGGAAAACCTTATAAGTGGA
GGCCAGATTTTTACTTCTATAGAGGAGGTACCGGGGTATTATGGCAGCTCACCGGAACTTAATTTTCCGGCCCGGCTAAA
CAATGGGTTTAATGAACTTCCGGTTATGGGAAAGGGGATTATTCCCGATAAATTTACCCGGGTCTTTCCCATTAAAGATA
AGTTTGTCGAAGGGGAGATGTTTTCCCGGGGAGAATACAAAGTGGTTATGGGGAAGCGGCTTGCTGAATTGATGAAATTA
CAGTTAGGGGATTATATCACCCTGCTGGTAAAAGATAAAAATGAAACCTTTAATACTATCGAAGCAGAAATATCTGGTTT
GATTCACACCGCTAACCCCAATGTTAATCGTAATATTGTGTACCTTCCCCTTGATATTGCCCAACAGACCCTTGGTGTCG
GTAACCGGGTGAGCAAGGTTATTGTAAGGCTGGAAGATAAGGAACTGGCCAGTATGGCTGCCAGGGAACTGAAAAAGCAA
CTGGGGAAAACCGAGACTGGACTGGGGGTTTACCCCTGGAGTGAACTGGAGGCTGTTACCATAGCGGGAGCTAAAAATGC
AGGTAACCAGCTGGTGTTAACTATTATTTTAATAATTGCTGCCATTGCTATTATCAATACTGTTATCCTGGCGGCCCTGG
AAAGAATGGAAGAAATCGGGATGATGAAGGCTATGGGTCTACGGGTCAAAGAGATTGTCTTTGTGTTTGTTGCGGAATCA
ACCGGCATAGGAATCCTCGGAGGCTCAGTCGGTATCCTTATGGGAGCAATTGGTGTCTGGTTTTTAAACTCCTACGGGAT
AGATTTTTCAATAATGACCAACATGGATATGACTTCATTCGGTATACCGATCCTGGGTAAGGTTTATGGGATCTGGAATC
CTTCGTCCTTTATAATGGTTTTTGCCTTCGGGATTGTTGTTTCCCTATTATCGAGTATTCTTCCAGCTTACTGGGCGGCA
GCCAAGGACCCAATTAAGGCGATTTATCATCGTTAG

Upstream 100 bases:

>100_bases
TGGAATTTGCTTAATTCTTAATGGCTAAGTTAAAGGTAAGTTAAAGGGGGAATGAGATATGCCATTCCAGAAAAGTAAAA
CATCAGAGGGGGGAGGATAA

Downstream 100 bases:

>100_bases
GGGGGTGTAAAATGTCGTATCTTTTTAAAATTGCCTTCAAAAATTTATTCAGGCACAGGCTAAGAACTCTCGTTTCCATA
GTGGCCATTGCCTTTTCGGT

Product: lipoprotein release ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MFLAKLAFKNLVRHRNRTLITASIIAIAIFFFLLLDSLIGGMTEMSYDTIINYEAGHLQLAHREYWEEEEELPLENLISG
GQIFTSIEEVPGYYGSSPELNFPARLNNGFNELPVMGKGIIPDKFTRVFPIKDKFVEGEMFSRGEYKVVMGKRLAELMKL
QLGDYITLLVKDKNETFNTIEAEISGLIHTANPNVNRNIVYLPLDIAQQTLGVGNRVSKVIVRLEDKELASMAARELKKQ
LGKTETGLGVYPWSELEAVTIAGAKNAGNQLVLTIILIIAAIAIINTVILAALERMEEIGMMKAMGLRVKEIVFVFVAES
TGIGILGGSVGILMGAIGVWFLNSYGIDFSIMTNMDMTSFGIPILGKVYGIWNPSSFIMVFAFGIVVSLLSSILPAYWAA
AKDPIKAIYHR

Sequences:

>Translated_411_residues
MFLAKLAFKNLVRHRNRTLITASIIAIAIFFFLLLDSLIGGMTEMSYDTIINYEAGHLQLAHREYWEEEEELPLENLISG
GQIFTSIEEVPGYYGSSPELNFPARLNNGFNELPVMGKGIIPDKFTRVFPIKDKFVEGEMFSRGEYKVVMGKRLAELMKL
QLGDYITLLVKDKNETFNTIEAEISGLIHTANPNVNRNIVYLPLDIAQQTLGVGNRVSKVIVRLEDKELASMAARELKKQ
LGKTETGLGVYPWSELEAVTIAGAKNAGNQLVLTIILIIAAIAIINTVILAALERMEEIGMMKAMGLRVKEIVFVFVAES
TGIGILGGSVGILMGAIGVWFLNSYGIDFSIMTNMDMTSFGIPILGKVYGIWNPSSFIMVFAFGIVVSLLSSILPAYWAA
AKDPIKAIYHR
>Mature_411_residues
MFLAKLAFKNLVRHRNRTLITASIIAIAIFFFLLLDSLIGGMTEMSYDTIINYEAGHLQLAHREYWEEEEELPLENLISG
GQIFTSIEEVPGYYGSSPELNFPARLNNGFNELPVMGKGIIPDKFTRVFPIKDKFVEGEMFSRGEYKVVMGKRLAELMKL
QLGDYITLLVKDKNETFNTIEAEISGLIHTANPNVNRNIVYLPLDIAQQTLGVGNRVSKVIVRLEDKELASMAARELKKQ
LGKTETGLGVYPWSELEAVTIAGAKNAGNQLVLTIILIIAAIAIINTVILAALERMEEIGMMKAMGLRVKEIVFVFVAES
TGIGILGGSVGILMGAIGVWFLNSYGIDFSIMTNMDMTSFGIPILGKVYGIWNPSSFIMVFAFGIVVSLLSSILPAYWAA
AKDPIKAIYHR

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=262, Percent_Identity=21.7557251908397, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925
- InterPro:   IPR011926 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45471; Mature: 45471

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLAKLAFKNLVRHRNRTLITASIIAIAIFFFLLLDSLIGGMTEMSYDTIINYEAGHLQL
CCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHEEECCCCCEEH
AHREYWEEEEELPLENLISGGQIFTSIEEVPGYYGSSPELNFPARLNNGFNELPVMGKGI
HHHHHCCCHHCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCC
IPDKFTRVFPIKDKFVEGEMFSRGEYKVVMGKRLAELMKLQLGDYITLLVKDKNETFNTI
CCCCCCEEECCHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHH
EAEISGLIHTANPNVNRNIVYLPLDIAQQTLGVGNRVSKVIVRLEDKELASMAARELKKQ
HHHHHCEEECCCCCCCCEEEEEEHHHHHHHHCCCHHHHHHHHEECHHHHHHHHHHHHHHH
LGKTETGLGVYPWSELEAVTIAGAKNAGNQLVLTIILIIAAIAIINTVILAALERMEEIG
HCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMKAMGLRVKEIVFVFVAESTGIGILGGSVGILMGAIGVWFLNSYGIDFSIMTNMDMTSF
HHHHHCCHHHHEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHC
GIPILGKVYGIWNPSSFIMVFAFGIVVSLLSSILPAYWAAAKDPIKAIYHR
CCCHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MFLAKLAFKNLVRHRNRTLITASIIAIAIFFFLLLDSLIGGMTEMSYDTIINYEAGHLQL
CCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHEEECCCCCEEH
AHREYWEEEEELPLENLISGGQIFTSIEEVPGYYGSSPELNFPARLNNGFNELPVMGKGI
HHHHHCCCHHCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCC
IPDKFTRVFPIKDKFVEGEMFSRGEYKVVMGKRLAELMKLQLGDYITLLVKDKNETFNTI
CCCCCCEEECCHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHH
EAEISGLIHTANPNVNRNIVYLPLDIAQQTLGVGNRVSKVIVRLEDKELASMAARELKKQ
HHHHHCEEECCCCCCCCEEEEEEHHHHHHHHCCCHHHHHHHHEECHHHHHHHHHHHHHHH
LGKTETGLGVYPWSELEAVTIAGAKNAGNQLVLTIILIIAAIAIINTVILAALERMEEIG
HCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMKAMGLRVKEIVFVFVAESTGIGILGGSVGILMGAIGVWFLNSYGIDFSIMTNMDMTSF
HHHHHCCHHHHEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHC
GIPILGKVYGIWNPSSFIMVFAFGIVVSLLSSILPAYWAAAKDPIKAIYHR
CCCHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10783239 [H]