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The map label for this gene is lolC [H]

Identifier: 220933158

GI number: 220933158

Start: 2544887

End: 2546146

Strand: Reverse

Name: lolC [H]

Synonym: Hore_23260

Alternate gene names: 220933158

Gene position: 2546146-2544887 (Counterclockwise)

Preceding gene: 220933159

Following gene: 220933157

Centisome position: 98.76

GC content: 43.17

Gene sequence:

>1260_bases
ATGTCGTATCTTTTTAAAATTGCCTTCAAAAATTTATTCAGGCACAGGCTAAGAACTCTCGTTTCCATAGTGGCCATTGC
CTTTTCGGTAATGATTGTTGTTTTTGCCCGGGGGTATATTGTAGGGTTAATTGATAGTATTTCTGCTGATCATATTCAAT
ATAATTCAGGACATATTAAGATAGTGAACCGGGATTATCTCCAGCAGGAGCGTCTCCTTCCCCTTAATTATCCGGTAGAT
GGCTTTAAAGGTCAGGGAGTGGAGGAAATGGCTTCTGATTTGAAAAATATAGACAGGGTGGAGATGGTTATTCCCAGACT
GAAGTTTGGGGCCATGGTAAGCACCGACAAAGAGTTGATAACCATGAATGGCTGGGGGGTTAATCCAGAACAGGAGATAG
CCTTTACCAGTATTGAAGATTACCTGGTAGAGGGACGGATGATTAAACCGGGTCGCCTCGAAGTGGTGATGGGAAGTGGG
TTGTTGAATAAAATAAACCGTCAGGTTGGTGATAAAGTAACGATTGTTTTCAAAACATCCTTCAACTCCCTAAGAGGAGT
TACTTTTAGAATAGTCGGACGGCTGGAGACCGGTATTAAGCTGCTCAATGAAGTTGCCTTTTTTTTGCCCCTTGACCAGG
CCCAGCGCCTTTTATATATGGAGGGACAGGCGACAGAATTGTTACTGGTAAGTTCTGATAAAAAGCTGGTTGACCAGATC
CTTCCCGAAGTGAAAAAGGTTCTGGCAGAACGGGGAGAAGAAAATAGATATGTGGCCCTGGGGTATAAGGAAACCAGTGA
CCTTTTACCCTATATGGAGCTGGCTAAACTGATTTATAACCAGGTTTACATTTTTCTGGTATTACTGGCCAGTATTGTGG
TTATCAATACCATGATTATGATTGTTAAAGAGAGGACCAGGGAAATAGGTATGATGTCAGCTATGGGACTGGAGAGCAGA
GGTATCTTAAAGCTCTTCCTGATTGAGGGCGGTATAATAGGAACCATCGGCAGTCTGATCGGGGCTATTCTGGGCTCAGT
TATAACTGACTATTTTGCCAGGACCGGCCTTAATTTTTCCTCAGCGACAGCAGGTTTCAGCCCGGAGATAGTTTTTAATT
CAATTATTTATCCAGTTTCCTCAGTTGGAAATACTGTTTTTGCTTTCTTTCTGGGAGTACTGGTTGTTACCATGGGTTGT
CTTATTCCAGCCAGGAGGGCAGCTCGCATGAAACCGACGGAAGCCTTACGGGAAATATAA

Upstream 100 bases:

>100_bases
TCGGGATTGTTGTTTCCCTATTATCGAGTATTCTTCCAGCTTACTGGGCGGCAGCCAAGGACCCAATTAAGGCGATTTAT
CATCGTTAGGGGGGTGTAAA

Downstream 100 bases:

>100_bases
TTTTAGACCTTTTAATTAAAGTAAGGAGGAATGGTTATGTCATTACTGGAACTTAACGGCATCAAGAAAATTTATCAGCA
GGGTAAGGTAGAGGTACCTG

Product: lipoprotein release ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MSYLFKIAFKNLFRHRLRTLVSIVAIAFSVMIVVFARGYIVGLIDSISADHIQYNSGHIKIVNRDYLQQERLLPLNYPVD
GFKGQGVEEMASDLKNIDRVEMVIPRLKFGAMVSTDKELITMNGWGVNPEQEIAFTSIEDYLVEGRMIKPGRLEVVMGSG
LLNKINRQVGDKVTIVFKTSFNSLRGVTFRIVGRLETGIKLLNEVAFFLPLDQAQRLLYMEGQATELLLVSSDKKLVDQI
LPEVKKVLAERGEENRYVALGYKETSDLLPYMELAKLIYNQVYIFLVLLASIVVINTMIMIVKERTREIGMMSAMGLESR
GILKLFLIEGGIIGTIGSLIGAILGSVITDYFARTGLNFSSATAGFSPEIVFNSIIYPVSSVGNTVFAFFLGVLVVTMGC
LIPARRAARMKPTEALREI

Sequences:

>Translated_419_residues
MSYLFKIAFKNLFRHRLRTLVSIVAIAFSVMIVVFARGYIVGLIDSISADHIQYNSGHIKIVNRDYLQQERLLPLNYPVD
GFKGQGVEEMASDLKNIDRVEMVIPRLKFGAMVSTDKELITMNGWGVNPEQEIAFTSIEDYLVEGRMIKPGRLEVVMGSG
LLNKINRQVGDKVTIVFKTSFNSLRGVTFRIVGRLETGIKLLNEVAFFLPLDQAQRLLYMEGQATELLLVSSDKKLVDQI
LPEVKKVLAERGEENRYVALGYKETSDLLPYMELAKLIYNQVYIFLVLLASIVVINTMIMIVKERTREIGMMSAMGLESR
GILKLFLIEGGIIGTIGSLIGAILGSVITDYFARTGLNFSSATAGFSPEIVFNSIIYPVSSVGNTVFAFFLGVLVVTMGC
LIPARRAARMKPTEALREI
>Mature_418_residues
SYLFKIAFKNLFRHRLRTLVSIVAIAFSVMIVVFARGYIVGLIDSISADHIQYNSGHIKIVNRDYLQQERLLPLNYPVDG
FKGQGVEEMASDLKNIDRVEMVIPRLKFGAMVSTDKELITMNGWGVNPEQEIAFTSIEDYLVEGRMIKPGRLEVVMGSGL
LNKINRQVGDKVTIVFKTSFNSLRGVTFRIVGRLETGIKLLNEVAFFLPLDQAQRLLYMEGQATELLLVSSDKKLVDQIL
PEVKKVLAERGEENRYVALGYKETSDLLPYMELAKLIYNQVYIFLVLLASIVVINTMIMIVKERTREIGMMSAMGLESRG
ILKLFLIEGGIIGTIGSLIGAILGSVITDYFARTGLNFSSATAGFSPEIVFNSIIYPVSSVGNTVFAFFLGVLVVTMGCL
IPARRAARMKPTEALREI

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=275, Percent_Identity=23.2727272727273, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46732; Mature: 46601

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYLFKIAFKNLFRHRLRTLVSIVAIAFSVMIVVFARGYIVGLIDSISADHIQYNSGHIK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEE
IVNRDYLQQERLLPLNYPVDGFKGQGVEEMASDLKNIDRVEMVIPRLKFGAMVSTDKELI
EEEHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCEECCCCCEE
TMNGWGVNPEQEIAFTSIEDYLVEGRMIKPGRLEVVMGSGLLNKINRQVGDKVTIVFKTS
EECCCCCCCCHHHHHHHHHHHHHCCEEECCCCEEEEECCHHHHHHHHHCCCEEEEEEEEC
FNSLRGVTFRIVGRLETGIKLLNEVAFFLPLDQAQRLLYMEGQATELLLVSSDKKLVDQI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCCEEEEEECCHHHHHHH
LPEVKKVLAERGEENRYVALGYKETSDLLPYMELAKLIYNQVYIFLVLLASIVVINTMIM
HHHHHHHHHHCCCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVKERTREIGMMSAMGLESRGILKLFLIEGGIIGTIGSLIGAILGSVITDYFARTGLNFS
HHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SATAGFSPEIVFNSIIYPVSSVGNTVFAFFLGVLVVTMGCLIPARRAARMKPTEALREI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
>Mature Secondary Structure 
SYLFKIAFKNLFRHRLRTLVSIVAIAFSVMIVVFARGYIVGLIDSISADHIQYNSGHIK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEE
IVNRDYLQQERLLPLNYPVDGFKGQGVEEMASDLKNIDRVEMVIPRLKFGAMVSTDKELI
EEEHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCEECCCCCEE
TMNGWGVNPEQEIAFTSIEDYLVEGRMIKPGRLEVVMGSGLLNKINRQVGDKVTIVFKTS
EECCCCCCCCHHHHHHHHHHHHHCCEEECCCCEEEEECCHHHHHHHHHCCCEEEEEEEEC
FNSLRGVTFRIVGRLETGIKLLNEVAFFLPLDQAQRLLYMEGQATELLLVSSDKKLVDQI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCCEEEEEECCHHHHHHH
LPEVKKVLAERGEENRYVALGYKETSDLLPYMELAKLIYNQVYIFLVLLASIVVINTMIM
HHHHHHHHHHCCCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVKERTREIGMMSAMGLESRGILKLFLIEGGIIGTIGSLIGAILGSVITDYFARTGLNFS
HHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SATAGFSPEIVFNSIIYPVSSVGNTVFAFFLGVLVVTMGCLIPARRAARMKPTEALREI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]