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The map label for this gene is galE [C]

Identifier: 220933110

GI number: 220933110

Start: 2486822

End: 2487778

Strand: Reverse

Name: galE [C]

Synonym: Hore_22780

Alternate gene names: 220933110

Gene position: 2487778-2486822 (Counterclockwise)

Preceding gene: 220933111

Following gene: 220933109

Centisome position: 96.49

GC content: 36.68

Gene sequence:

>957_bases
ATGATTATTTTAGCAACCGGTGGAGCAGGTTTTATCGGCTCAAATATAGTAGATAAGTTAATAAATATAGGACATGATGT
GGTTGTTGTGGACAACCTTTCTACGGGCTATAAGACAAACCTTAATTCTACAGCTAAATTTTATAAAGTAGATATAATAT
CATCAGATATAGAAGATATTATAAAAAAAGAAAAAATAACCCACGTAATTCATCATGCAGCCCAGATAGATGTCCAGCGT
TCTGTTAAAGATCCCATTTTTGATGCTGATAATAATATAAAAGGTACCATTAATTTACTCGAGGCCTGCCGTAAAAATAA
TGTAGAAAAGATAATATATGCTTCTTCAGCTGCGGTCTATGGAGAACCCGATTATTTACCCATTGATGAAAGCCATCCTA
TAAAAGCCATGTCTCCCTATGGTATTAGTAAACATACCCCGGAGCATTACATAAAGATGTATGGAGAATTATATGATTTA
AAATATACCATTTTAAGGTATGCCAATGTTTACGGTCCCCGCCAGGATCCAAAAGGAGAGGGTGGGGTAGTCTCTATATT
TACTGATAAAATGGTGAACGGTGAACAGCCAGCAATTTATGGAGATGGGAAACAGACACGTGATTTTATTTATGTCGAAG
ATATCGTTGCAGCCAATCTTAAAGCTCTTAATAGAGGTGATAATCAAATAGTTAATATTAGTACCAGGACTCAGACCAGT
GTCATTGAATTATTTAAAACTATGAAAGATATCCTGAAAATGGATATAGAACCCATATTTAATCGGGAAAGGCCAGGGGA
TATTCGCCATAGTTACCTTGATAACTCCCGGGCTAAAGAGGTTTTAGACTGGGCTCCACGGTATGACTTAAAGTCAGGGT
TAACCAGGACAATATCGTATTATGCCCGTCAACTTGGTTTAGATGAGGTAGCGACTACCCTGGAAGAAAGCTTATAA

Upstream 100 bases:

>100_bases
TATTAACTATTTTATTAATGGATTAAGTAAATATTTAAAATGAAAATTTATTAAAAAATCCTTTGTAACTAATACTAAAT
AAAATAGGAGACTGTTAATA

Downstream 100 bases:

>100_bases
AATTTTACTTTTATTAATCATAGTATATGTTTATTTGCTAAAGTGCTCTAAATATATTATCATAAACATATAAGTGAATA
ATTTAACAAGGTACTGGAGG

Product: Nucleoside-diphosphate-sugar epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MIILATGGAGFIGSNIVDKLINIGHDVVVVDNLSTGYKTNLNSTAKFYKVDIISSDIEDIIKKEKITHVIHHAAQIDVQR
SVKDPIFDADNNIKGTINLLEACRKNNVEKIIYASSAAVYGEPDYLPIDESHPIKAMSPYGISKHTPEHYIKMYGELYDL
KYTILRYANVYGPRQDPKGEGGVVSIFTDKMVNGEQPAIYGDGKQTRDFIYVEDIVAANLKALNRGDNQIVNISTRTQTS
VIELFKTMKDILKMDIEPIFNRERPGDIRHSYLDNSRAKEVLDWAPRYDLKSGLTRTISYYARQLGLDEVATTLEESL

Sequences:

>Translated_318_residues
MIILATGGAGFIGSNIVDKLINIGHDVVVVDNLSTGYKTNLNSTAKFYKVDIISSDIEDIIKKEKITHVIHHAAQIDVQR
SVKDPIFDADNNIKGTINLLEACRKNNVEKIIYASSAAVYGEPDYLPIDESHPIKAMSPYGISKHTPEHYIKMYGELYDL
KYTILRYANVYGPRQDPKGEGGVVSIFTDKMVNGEQPAIYGDGKQTRDFIYVEDIVAANLKALNRGDNQIVNISTRTQTS
VIELFKTMKDILKMDIEPIFNRERPGDIRHSYLDNSRAKEVLDWAPRYDLKSGLTRTISYYARQLGLDEVATTLEESL
>Mature_318_residues
MIILATGGAGFIGSNIVDKLINIGHDVVVVDNLSTGYKTNLNSTAKFYKVDIISSDIEDIIKKEKITHVIHHAAQIDVQR
SVKDPIFDADNNIKGTINLLEACRKNNVEKIIYASSAAVYGEPDYLPIDESHPIKAMSPYGISKHTPEHYIKMYGELYDL
KYTILRYANVYGPRQDPKGEGGVVSIFTDKMVNGEQPAIYGDGKQTRDFIYVEDIVAANLKALNRGDNQIVNISTRTQTS
VIELFKTMKDILKMDIEPIFNRERPGDIRHSYLDNSRAKEVLDWAPRYDLKSGLTRTISYYARQLGLDEVATTLEESL

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=308, Percent_Identity=30.5194805194805, Blast_Score=144, Evalue=9e-35,
Organism=Homo sapiens, GI7657641, Length=317, Percent_Identity=32.1766561514196, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI56237023, Length=322, Percent_Identity=30.1242236024845, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI56118217, Length=322, Percent_Identity=30.1242236024845, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI189083684, Length=322, Percent_Identity=30.1242236024845, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI193211614, Length=223, Percent_Identity=28.6995515695067, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI8393516, Length=223, Percent_Identity=28.6995515695067, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI48994969, Length=337, Percent_Identity=30.5637982195846, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1786974, Length=312, Percent_Identity=30.1282051282051, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788353, Length=340, Percent_Identity=30.2941176470588, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790049, Length=250, Percent_Identity=32.4, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788589, Length=342, Percent_Identity=23.9766081871345, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788365, Length=323, Percent_Identity=22.9102167182663, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17539532, Length=309, Percent_Identity=30.0970873786408, Blast_Score=137, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71982035, Length=321, Percent_Identity=32.0872274143302, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI71982038, Length=323, Percent_Identity=31.8885448916409, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17568069, Length=330, Percent_Identity=30.3030303030303, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI115532424, Length=325, Percent_Identity=28, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319493, Length=325, Percent_Identity=31.3846153846154, Blast_Score=131, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321437, Length=354, Percent_Identity=24.8587570621469, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356223, Length=319, Percent_Identity=31.974921630094, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI19923002, Length=319, Percent_Identity=31.974921630094, Blast_Score=147, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35722; Mature: 35722

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILATGGAGFIGSNIVDKLINIGHDVVVVDNLSTGYKTNLNSTAKFYKVDIISSDIEDI
CEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEEEEHHHHHHH
IKKEKITHVIHHAAQIDVQRSVKDPIFDADNNIKGTINLLEACRKNNVEKIIYASSAAVY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCEEEC
GEPDYLPIDESHPIKAMSPYGISKHTPEHYIKMYGELYDLKYTILRYANVYGPRQDPKGE
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GGVVSIFTDKMVNGEQPAIYGDGKQTRDFIYVEDIVAANLKALNRGDNQIVNISTRTQTS
CCEEEEEECCCCCCCCCEEECCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEEECCHHHH
VIELFKTMKDILKMDIEPIFNRERPGDIRHSYLDNSRAKEVLDWAPRYDLKSGLTRTISY
HHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHH
YARQLGLDEVATTLEESL
HHHHHCHHHHHHHHHHCC
>Mature Secondary Structure
MIILATGGAGFIGSNIVDKLINIGHDVVVVDNLSTGYKTNLNSTAKFYKVDIISSDIEDI
CEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEEEEHHHHHHH
IKKEKITHVIHHAAQIDVQRSVKDPIFDADNNIKGTINLLEACRKNNVEKIIYASSAAVY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCEEEC
GEPDYLPIDESHPIKAMSPYGISKHTPEHYIKMYGELYDLKYTILRYANVYGPRQDPKGE
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GGVVSIFTDKMVNGEQPAIYGDGKQTRDFIYVEDIVAANLKALNRGDNQIVNISTRTQTS
CCEEEEEECCCCCCCCCEEECCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEEECCHHHH
VIELFKTMKDILKMDIEPIFNRERPGDIRHSYLDNSRAKEVLDWAPRYDLKSGLTRTISY
HHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHH
YARQLGLDEVATTLEESL
HHHHHCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]