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The map label for this gene is yabD [H]

Identifier: 220933025

GI number: 220933025

Start: 2383108

End: 2383881

Strand: Reverse

Name: yabD [H]

Synonym: Hore_21920

Alternate gene names: 220933025

Gene position: 2383881-2383108 (Counterclockwise)

Preceding gene: 220933026

Following gene: 220933024

Centisome position: 92.46

GC content: 44.06

Gene sequence:

>774_bases
ATGCAGTTAATAGATACCCATGCCCATCTTGATTTTCCCCGTTTTAAGAAAGACCGGGTTAAGGTTATCAAACGGGCGGA
GGAAGATGGTGTGAAGTATATTATAAACGTCGGGGCTGACCTGGCCTCGAGTCACCGTTCCCTGAGATTGAGTCAGGAGT
ATGATCATATTTTTGCAACTGTAGGGATTCATCCCCATGATGCTGATCAGGTTGATGGCCGGGCCCTCAAGGTTTTAAAG
GATCTGGCTAAGGCAGATAAAGTGGTAGCTATTGGAGAAATAGGTCTGGATTATTATTATGATAATTCCCCCCGTGATGT
TCAGAAGGAGGCCTTTAAAAGGCAACTTGAGCTGGCCCACAAACTTAAATTACCGGTTGTTATCCACAGCCGGGAGGCTG
ATGAGGATACCCTGGAAATTCTGAAGGAGATGGAGGTTGGTGAACTCGGGGGAGTAATGCACTGTTTTGCCGGTCATTTA
GAAATGGCCAGGGAATGTTTGAGTTTAAATATGTACCTGGCTTTTGGAGGGGTAATTACCTTTAAAAATGCTGATAAGAC
CAGGGAGGTAGTCAGAGAGATTCCACTTGACAGGATTCTGATTGAAACTGATAGCCCCTATCTTACCCCTCACCCCTACC
GTGGAAAGAGAAATGAACCTTCTTATGTCAGATTTGTTGCCGAAAAGATTGCTGAACTTAAGGATAAGTCTATGGAGGAA
ATTACCCGGATAACTACTGCAAATGCCATTAATGCCTTTAACTTATCATTGTAG

Upstream 100 bases:

>100_bases
TTGTATATAACTGACCAGATACTTTATGTTTTGTAAAAACGGTGGTATAATAAATTTTGATAAAACTGACAGTTATTATA
AGTAAACAGAGGTGAAGCCA

Downstream 100 bases:

>100_bases
GAACGGTTAAGGGGTACGGTCATTATATAGTGGTAATGTAGTATGATTTTATTGTGGTTAGATTGCTGGGTAAAAGAATA
ATATTTAAAAGATAATTTTA

Product: hydrolase, TatD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MQLIDTHAHLDFPRFKKDRVKVIKRAEEDGVKYIINVGADLASSHRSLRLSQEYDHIFATVGIHPHDADQVDGRALKVLK
DLAKADKVVAIGEIGLDYYYDNSPRDVQKEAFKRQLELAHKLKLPVVIHSREADEDTLEILKEMEVGELGGVMHCFAGHL
EMARECLSLNMYLAFGGVITFKNADKTREVVREIPLDRILIETDSPYLTPHPYRGKRNEPSYVRFVAEKIAELKDKSMEE
ITRITTANAINAFNLSL

Sequences:

>Translated_257_residues
MQLIDTHAHLDFPRFKKDRVKVIKRAEEDGVKYIINVGADLASSHRSLRLSQEYDHIFATVGIHPHDADQVDGRALKVLK
DLAKADKVVAIGEIGLDYYYDNSPRDVQKEAFKRQLELAHKLKLPVVIHSREADEDTLEILKEMEVGELGGVMHCFAGHL
EMARECLSLNMYLAFGGVITFKNADKTREVVREIPLDRILIETDSPYLTPHPYRGKRNEPSYVRFVAEKIAELKDKSMEE
ITRITTANAINAFNLSL
>Mature_257_residues
MQLIDTHAHLDFPRFKKDRVKVIKRAEEDGVKYIINVGADLASSHRSLRLSQEYDHIFATVGIHPHDADQVDGRALKVLK
DLAKADKVVAIGEIGLDYYYDNSPRDVQKEAFKRQLELAHKLKLPVVIHSREADEDTLEILKEMEVGELGGVMHCFAGHL
EMARECLSLNMYLAFGGVITFKNADKTREVVREIPLDRILIETDSPYLTPHPYRGKRNEPSYVRFVAEKIAELKDKSMEE
ITRITTANAINAFNLSL

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=292, Percent_Identity=31.1643835616438, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI110349730, Length=268, Percent_Identity=31.7164179104478, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI110349734, Length=268, Percent_Identity=32.089552238806, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI226061853, Length=273, Percent_Identity=31.5018315018315, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI225903424, Length=220, Percent_Identity=37.2727272727273, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI225903439, Length=246, Percent_Identity=31.3008130081301, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI226061614, Length=260, Percent_Identity=29.2307692307692, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI226061595, Length=230, Percent_Identity=29.5652173913043, Blast_Score=94, Evalue=9e-20,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=40.6976744186046, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI48994985, Length=261, Percent_Identity=32.183908045977, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI87082439, Length=256, Percent_Identity=33.203125, Blast_Score=149, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=32.3843416370107, Blast_Score=156, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI71980746, Length=267, Percent_Identity=30.3370786516854, Blast_Score=113, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17543026, Length=221, Percent_Identity=36.1990950226244, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17565396, Length=210, Percent_Identity=35.2380952380952, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24648690, Length=284, Percent_Identity=33.8028169014084, Blast_Score=140, Evalue=9e-34,
Organism=Drosophila melanogaster, GI221330018, Length=301, Percent_Identity=30.5647840531561, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24586117, Length=270, Percent_Identity=31.1111111111111, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29239; Mature: 29239

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLIDTHAHLDFPRFKKDRVKVIKRAEEDGVKYIINVGADLASSHRSLRLSQEYDHIFAT
CCEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHEECHHHHCEEEEE
VGIHPHDADQVDGRALKVLKDLAKADKVVAIGEIGLDYYYDNSPRDVQKEAFKRQLELAH
ECCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHH
KLKLPVVIHSREADEDTLEILKEMEVGELGGVMHCFAGHLEMARECLSLNMYLAFGGVIT
HCCCCEEEECCCCCHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHEEEECCEEE
FKNADKTREVVREIPLDRILIETDSPYLTPHPYRGKRNEPSYVRFVAEKIAELKDKSMEE
ECCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ITRITTANAINAFNLSL
HHHHHHHCCCCEEECCC
>Mature Secondary Structure
MQLIDTHAHLDFPRFKKDRVKVIKRAEEDGVKYIINVGADLASSHRSLRLSQEYDHIFAT
CCEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHEECHHHHCEEEEE
VGIHPHDADQVDGRALKVLKDLAKADKVVAIGEIGLDYYYDNSPRDVQKEAFKRQLELAH
ECCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHH
KLKLPVVIHSREADEDTLEILKEMEVGELGGVMHCFAGHLEMARECLSLNMYLAFGGVIT
HCCCCEEEECCCCCHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHEEEECCEEE
FKNADKTREVVREIPLDRILIETDSPYLTPHPYRGKRNEPSYVRFVAEKIAELKDKSMEE
ECCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ITRITTANAINAFNLSL
HHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]