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The map label for this gene is 220932829

Identifier: 220932829

GI number: 220932829

Start: 2151721

End: 2152263

Strand: Reverse

Name: 220932829

Synonym: Hore_19950

Alternate gene names: NA

Gene position: 2152263-2151721 (Counterclockwise)

Preceding gene: 220932830

Following gene: 220932828

Centisome position: 83.48

GC content: 39.04

Gene sequence:

>543_bases
ATGCCTAACAATATTTTTTTAAGTGGTGATGACGGGAGTGGTAAATCAACCATTATCAAAAATGTAATTCAGGAACTCGG
TTTAAATTCCGGGGGGTTTATTATCAAGGAAATAGTAGAAGAAGAGAGAGACTGGACAGAATGTTTTCTGATTGACGCCA
GGGTTTTGTGTGGAAATAACCAGGTTCCGGAGCTTGATCCTGAGAATATTGTTGCCAGACGGCAGGGAGATGAGACCTGG
CACATAAGGAGCAGTGTTTATGATAAAAAGGGGGTAGAACTCCTGGCCAGGGGTTTTGTATCCAGTGACATTCTCGTTAT
AGATAGACTGGGAGAATTTGAACTTAAAGCAAATGTCTTTATAAATAAAATAGAAGGCTTACTCGATACCCCTAAACCCG
TCCTGGGAGCTGTCAACGTTAAAAATAATCCCTTTATAAATAATTTAATGGAAAGAAGGGATTGTGAGTTTTTTGTAGTA
AGTAAAGAGTCACGGGAAAGGGTCTATAATGAGGTTCTGGAAAGGGTAAAAGATATACTGTAA

Upstream 100 bases:

>100_bases
ATAAAAGGCCATGAATATATTAAATATACCAATCTGGTTACTGGCATTAAGTTGACTTTGGTTAATACTTTTTTATTAGA
CAGGCTGGGGGGAGGTTTTT

Downstream 100 bases:

>100_bases
GGAATACTATTAGTTAAACAATAAAAAAAGTTATAATTGAGAACAAATAGATAGCAAAATTTTTGTCTGGAGAAAATATA
TGTAAGAACTTTATTTCATA

Product: nucleotide kinase

Products: NA

Alternate protein names: NTPase THEP1; Nucleoside triphosphate phosphohydrolase [H]

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MPNNIFLSGDDGSGKSTIIKNVIQELGLNSGGFIIKEIVEEERDWTECFLIDARVLCGNNQVPELDPENIVARRQGDETW
HIRSSVYDKKGVELLARGFVSSDILVIDRLGEFELKANVFINKIEGLLDTPKPVLGAVNVKNNPFINNLMERRDCEFFVV
SKESRERVYNEVLERVKDIL

Sequences:

>Translated_180_residues
MPNNIFLSGDDGSGKSTIIKNVIQELGLNSGGFIIKEIVEEERDWTECFLIDARVLCGNNQVPELDPENIVARRQGDETW
HIRSSVYDKKGVELLARGFVSSDILVIDRLGEFELKANVFINKIEGLLDTPKPVLGAVNVKNNPFINNLMERRDCEFFVV
SKESRERVYNEVLERVKDIL
>Mature_179_residues
PNNIFLSGDDGSGKSTIIKNVIQELGLNSGGFIIKEIVEEERDWTECFLIDARVLCGNNQVPELDPENIVARRQGDETWH
IRSSVYDKKGVELLARGFVSSDILVIDRLGEFELKANVFINKIEGLLDTPKPVLGAVNVKNNPFINNLMERRDCEFFVVS
KESRERVYNEVLERVKDIL

Specific function: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency [H]

COG id: COG1618

COG function: function code F; Predicted nucleotide kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the THEP1 NTPase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004948 [H]

Pfam domain/function: PF03266 DUF265 [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 20439; Mature: 20307

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNNIFLSGDDGSGKSTIIKNVIQELGLNSGGFIIKEIVEEERDWTECFLIDARVLCGNN
CCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHEEHHHEEECCC
QVPELDPENIVARRQGDETWHIRSSVYDKKGVELLARGFVSSDILVIDRLGEFELKANVF
CCCCCCHHHHHHHCCCCCEEEEHHHHCCHHHHHHHHHHHCCCCEEEEECCCCEEEHHHHH
INKIEGLLDTPKPVLGAVNVKNNPFINNLMERRDCEFFVVSKESRERVYNEVLERVKDIL
HHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PNNIFLSGDDGSGKSTIIKNVIQELGLNSGGFIIKEIVEEERDWTECFLIDARVLCGNN
CCCEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHEEHHHEEECCC
QVPELDPENIVARRQGDETWHIRSSVYDKKGVELLARGFVSSDILVIDRLGEFELKANVF
CCCCCCHHHHHHHCCCCCEEEEHHHHCCHHHHHHHHHHHCCCCEEEEECCCCEEEHHHHH
INKIEGLLDTPKPVLGAVNVKNNPFINNLMERRDCEFFVVSKESRERVYNEVLERVKDIL
HHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]