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The map label for this gene is inlA [H]

Identifier: 220932817

GI number: 220932817

Start: 2135765

End: 2137360

Strand: Reverse

Name: inlA [H]

Synonym: Hore_19830

Alternate gene names: 220932817

Gene position: 2137360-2135765 (Counterclockwise)

Preceding gene: 220932818

Following gene: 220932816

Centisome position: 82.9

GC content: 35.96

Gene sequence:

>1596_bases
ATGAGTAAAAAGCCTTTTTCAAAAATAGTTACACTGTTTGTTATAATTATTTTTTCAATCTTTCTTTTTGCCTGGAATGG
GGAAGCTGTCGAAGATACAGGAATTATTGTTTTTGAAGATGAGGACCTGAAAAAAGTGGTAATGAGGTCACTGAGCAAGC
CGGAAGGACCTGTCTTCAGGCCAGAGGTGGAAAATTTAACTGAGTTCAGTATCCCCTCTTTTCGTCATTATGAAATAAAT
TCTATAAAGGGATTAGAAGCCTTTTTAAACATAAAAACCCTGCGGATTGGGCCAAATTATATCAGTGATTTAACCCCCCT
GGCCCATTTAACAGACCTTGAAAGACTCTATATCTTTGAAAATCATATTGAAGATTTAAGTCCACTGGGAAAATTGAAGG
AATTAAGGGAGTTAATAATCAGGGGGTTACCTCCATATAAAAAGGGATTGCCTTCAGGTAAATATTCAGGACATTATATT
GAGGACATAAGTCCTCTGGCCGGTTTAGTAAAACTTGAATACCTTAAATTATCCCATCAAAAGATATCAAATTTAGAGAC
CCTGACTCAACTACCAAACTTAAAAACCCTGAATGTAGCCTATAACAGTATATCTGACCTTAAACCCCTGACTGCTTTGA
CAGGGTTAAGCCACCTGGATCTGGAAGCCAACAATATTAAAGATATATCTCCATTAAGAGGGTTAAAAAAACTTACCTAT
TTAAATCTGATCAGAAATGAGTTGACCGGTGTAAAACACCTTTCCAGTCTGGAAGGTTTGCAGGTATTGCTGTTAAGCGG
GAATGACCTCCGGAATATTGCCTCCCTTACCCGACTGGTAAACCTTGAGAAACTGGATATCAGTGACAATAATATCAGTG
TTGCCCCCGGTTTAAAGGAATTTAAAGGTCTGAAGGAATTGAATATAAGTGGCAACCCCATTGACGATATTAATTTTATC
AGCGAGTGCAGGAAACTTGAAAGATTACTGGCCTTCAATTGTGAGATAAGGGACATATCACCTTTAAGGGGACATAACAG
TTTAAAAGAGCTTTTTTTGCATAACAACAGGATTACCGATATTAGTCCCCTTGAAGGGCTGAACACTCTCGAAAGGCTTG
ACCTGAGTGGAAATAGTATAGAAAATGTTTCAGTCATATCTGGACTCAATAAACTTAAATATTTAGACCTTGAGGGGTGT
GGTCTGACCGCGATAGAATTTTTAAAAGACCTGGGATCCCTGGAATACCTTGAACTTGAAAATAATAGAATAAGCCAGAT
TGAGCCTTTAAAAAAACATATTAATTTAAAAACCCTGGTTCTTGATAATAACCAGATTAAAGATATAAGTACCCTGGGTG
AATTGATGAACTTAAAGGTGCTATCATTAAACGATAATCAGATTGAAAACATCGATTCTTTGACTGGTTTAAACCAGCTG
GAAGTATTATATATTTCGGGCAATAGAATCAGGAATATTAAACCCCTTTTAAAATTAAATAATTTGAGTGTTGTAGCAAT
AAAAAATAATCAGTTTAAGCTTGATGAAGATGTTATAAAAAAGCTGGAGGATAATAAAGTAACTGTTGTGTATTGA

Upstream 100 bases:

>100_bases
AAAAACAACCATTTTAAACTAGATATAGAGGTTATAAATAAACTTAAGGATCGAGGGGTCAAAGTAGAATACTAGATATT
AACCGGGAGGTTATTTAAAT

Downstream 100 bases:

>100_bases
ACAATACTGTTTTGTTTCGGTAAAATTTGTGTGTTAAATTTGAATAAATTTTTTATGTTTCATGGTTCAGACAGGATTAA
GTATTCATGCTCCTGCTGAG

Product: leucine-rich repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MSKKPFSKIVTLFVIIIFSIFLFAWNGEAVEDTGIIVFEDEDLKKVVMRSLSKPEGPVFRPEVENLTEFSIPSFRHYEIN
SIKGLEAFLNIKTLRIGPNYISDLTPLAHLTDLERLYIFENHIEDLSPLGKLKELRELIIRGLPPYKKGLPSGKYSGHYI
EDISPLAGLVKLEYLKLSHQKISNLETLTQLPNLKTLNVAYNSISDLKPLTALTGLSHLDLEANNIKDISPLRGLKKLTY
LNLIRNELTGVKHLSSLEGLQVLLLSGNDLRNIASLTRLVNLEKLDISDNNISVAPGLKEFKGLKELNISGNPIDDINFI
SECRKLERLLAFNCEIRDISPLRGHNSLKELFLHNNRITDISPLEGLNTLERLDLSGNSIENVSVISGLNKLKYLDLEGC
GLTAIEFLKDLGSLEYLELENNRISQIEPLKKHINLKTLVLDNNQIKDISTLGELMNLKVLSLNDNQIENIDSLTGLNQL
EVLYISGNRIRNIKPLLKLNNLSVVAIKNNQFKLDEDVIKKLEDNKVTVVY

Sequences:

>Translated_531_residues
MSKKPFSKIVTLFVIIIFSIFLFAWNGEAVEDTGIIVFEDEDLKKVVMRSLSKPEGPVFRPEVENLTEFSIPSFRHYEIN
SIKGLEAFLNIKTLRIGPNYISDLTPLAHLTDLERLYIFENHIEDLSPLGKLKELRELIIRGLPPYKKGLPSGKYSGHYI
EDISPLAGLVKLEYLKLSHQKISNLETLTQLPNLKTLNVAYNSISDLKPLTALTGLSHLDLEANNIKDISPLRGLKKLTY
LNLIRNELTGVKHLSSLEGLQVLLLSGNDLRNIASLTRLVNLEKLDISDNNISVAPGLKEFKGLKELNISGNPIDDINFI
SECRKLERLLAFNCEIRDISPLRGHNSLKELFLHNNRITDISPLEGLNTLERLDLSGNSIENVSVISGLNKLKYLDLEGC
GLTAIEFLKDLGSLEYLELENNRISQIEPLKKHINLKTLVLDNNQIKDISTLGELMNLKVLSLNDNQIENIDSLTGLNQL
EVLYISGNRIRNIKPLLKLNNLSVVAIKNNQFKLDEDVIKKLEDNKVTVVY
>Mature_530_residues
SKKPFSKIVTLFVIIIFSIFLFAWNGEAVEDTGIIVFEDEDLKKVVMRSLSKPEGPVFRPEVENLTEFSIPSFRHYEINS
IKGLEAFLNIKTLRIGPNYISDLTPLAHLTDLERLYIFENHIEDLSPLGKLKELRELIIRGLPPYKKGLPSGKYSGHYIE
DISPLAGLVKLEYLKLSHQKISNLETLTQLPNLKTLNVAYNSISDLKPLTALTGLSHLDLEANNIKDISPLRGLKKLTYL
NLIRNELTGVKHLSSLEGLQVLLLSGNDLRNIASLTRLVNLEKLDISDNNISVAPGLKEFKGLKELNISGNPIDDINFIS
ECRKLERLLAFNCEIRDISPLRGHNSLKELFLHNNRITDISPLEGLNTLERLDLSGNSIENVSVISGLNKLKYLDLEGCG
LTAIEFLKDLGSLEYLELENNRISQIEPLKKHINLKTLVLDNNQIKDISTLGELMNLKVLSLNDNQIENIDSLTGLNQLE
VLYISGNRIRNIKPLLKLNNLSVVAIKNNQFKLDEDVIKKLEDNKVTVVY

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI4506013, Length=183, Percent_Identity=38.2513661202186, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI21389483, Length=212, Percent_Identity=33.4905660377358, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4504379, Length=333, Percent_Identity=29.4294294294294, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI62912470, Length=378, Percent_Identity=27.2486772486773, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI62912472, Length=379, Percent_Identity=28.2321899736148, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI238908508, Length=462, Percent_Identity=28.1385281385281, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17554124, Length=254, Percent_Identity=31.8897637795276, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17531555, Length=158, Percent_Identity=39.2405063291139, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536161, Length=209, Percent_Identity=34.4497607655502, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71984630, Length=373, Percent_Identity=27.8820375335121, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17563924, Length=427, Percent_Identity=25.5269320843091, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508137, Length=401, Percent_Identity=26.6832917705736, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71980576, Length=360, Percent_Identity=28.8888888888889, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322655, Length=215, Percent_Identity=33.4883720930233, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21358617, Length=208, Percent_Identity=33.1730769230769, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17648021, Length=387, Percent_Identity=26.6149870801034, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24667524, Length=512, Percent_Identity=27.9296875, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24664561, Length=435, Percent_Identity=26.2068965517241, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363494, Length=369, Percent_Identity=29.810298102981, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358607, Length=388, Percent_Identity=27.8350515463918, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28574432, Length=361, Percent_Identity=30.7479224376731, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17136436, Length=350, Percent_Identity=29.7142857142857, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221500776, Length=423, Percent_Identity=23.8770685579196, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650336, Length=361, Percent_Identity=28.808864265928, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI62472958, Length=361, Percent_Identity=28.808864265928, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24650334, Length=361, Percent_Identity=28.808864265928, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24650332, Length=361, Percent_Identity=28.808864265928, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24650330, Length=361, Percent_Identity=28.808864265928, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 59880; Mature: 59749

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKPFSKIVTLFVIIIFSIFLFAWNGEAVEDTGIIVFEDEDLKKVVMRSLSKPEGPVFR
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEECCCHHHHHHHHHCCCCCCCCCC
PEVENLTEFSIPSFRHYEINSIKGLEAFLNIKTLRIGPNYISDLTPLAHLTDLERLYIFE
CCHHCCHHCCCCCCEEEECCCCHHHHHHHEEEEEEECCHHHHHCCHHHHHHHHHHHHHHH
NHIEDLSPLGKLKELRELIIRGLPPYKKGLPSGKYSGHYIEDISPLAGLVKLEYLKLSHQ
HHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KISNLETLTQLPNLKTLNVAYNSISDLKPLTALTGLSHLDLEANNIKDISPLRGLKKLTY
HHHHHHHHHHCCCCEEEEEEHHCHHHCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
LNLIRNELTGVKHLSSLEGLQVLLLSGNDLRNIASLTRLVNLEKLDISDNNISVAPGLKE
HHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCEEEECCCCCEEECCCHHH
FKGLKELNISGNPIDDINFISECRKLERLLAFNCEIRDISPLRGHNSLKELFLHNNRITD
HCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCC
ISPLEGLNTLERLDLSGNSIENVSVISGLNKLKYLDLEGCGLTAIEFLKDLGSLEYLELE
CCCCCCCCHHHHHCCCCCCCCCHHHHHCCCHHEEEECCCCCHHHHHHHHHCCCEEEEEEC
NNRISQIEPLKKHINLKTLVLDNNQIKDISTLGELMNLKVLSLNDNQIENIDSLTGLNQL
CCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCCE
EVLYISGNRIRNIKPLLKLNNLSVVAIKNNQFKLDEDVIKKLEDNKVTVVY
EEEEEECCCCCCCCHHEEECCEEEEEEECCCEECCHHHHHHHCCCCEEEEC
>Mature Secondary Structure 
SKKPFSKIVTLFVIIIFSIFLFAWNGEAVEDTGIIVFEDEDLKKVVMRSLSKPEGPVFR
CCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEECCCHHHHHHHHHCCCCCCCCCC
PEVENLTEFSIPSFRHYEINSIKGLEAFLNIKTLRIGPNYISDLTPLAHLTDLERLYIFE
CCHHCCHHCCCCCCEEEECCCCHHHHHHHEEEEEEECCHHHHHCCHHHHHHHHHHHHHHH
NHIEDLSPLGKLKELRELIIRGLPPYKKGLPSGKYSGHYIEDISPLAGLVKLEYLKLSHQ
HHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KISNLETLTQLPNLKTLNVAYNSISDLKPLTALTGLSHLDLEANNIKDISPLRGLKKLTY
HHHHHHHHHHCCCCEEEEEEHHCHHHCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
LNLIRNELTGVKHLSSLEGLQVLLLSGNDLRNIASLTRLVNLEKLDISDNNISVAPGLKE
HHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCEEEECCCCCEEECCCHHH
FKGLKELNISGNPIDDINFISECRKLERLLAFNCEIRDISPLRGHNSLKELFLHNNRITD
HCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCC
ISPLEGLNTLERLDLSGNSIENVSVISGLNKLKYLDLEGCGLTAIEFLKDLGSLEYLELE
CCCCCCCCHHHHHCCCCCCCCCHHHHHCCCHHEEEECCCCCHHHHHHHHHCCCEEEEEEC
NNRISQIEPLKKHINLKTLVLDNNQIKDISTLGELMNLKVLSLNDNQIENIDSLTGLNQL
CCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCCE
EVLYISGNRIRNIKPLLKLNNLSVVAIKNNQFKLDEDVIKKLEDNKVTVVY
EEEEEECCCCCCCCHHEEECCEEEEEEECCCEECCHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]