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The map label for this gene is mcpB [H]

Identifier: 220932808

GI number: 220932808

Start: 2121164

End: 2123167

Strand: Reverse

Name: mcpB [H]

Synonym: Hore_19740

Alternate gene names: 220932808

Gene position: 2123167-2121164 (Counterclockwise)

Preceding gene: 220932809

Following gene: 220932807

Centisome position: 82.35

GC content: 36.83

Gene sequence:

>2004_bases
ATGAAAAGTAAAAAGAAGACCAATTTTAGGTTGAGAAGTAGTTTAACAATAAAAGTTATCGGGGTTGTCTTTCTTGTAGT
AGTAATTTTGGTTCTGTTTTTTGGAGTTACCATTAATTCTCTTGTATCAGAAGAGATTACTTCACTAGTTCAGGAAAGGA
ACTTTGGTATGGCATGTTCCATCCAGAGTGAAGTAGATGCTTTTATTAAGGAAACAGTTAATATGTTTGAGTTAACTTCA
AAACAGGATATAGTCAGGGCAGGCAGCAGGTTTCCAATGATGGATTTATTTAATAAAATTACAGCTGACTATCCACAGTT
TGTCTCTATGTACTTTGCTTCTGTTAAAGGGGAAATCATACATTTCCCGGTAGTTGAATTCTCACCGGATTATGATCCAG
TTCAGGAGGAATGGTACAAAAAGGCAGTAACTACAGAAGGTCTGGTAATAGGTAACCTGAAAAAAAATAAGAACGATGGT
TATCCGGTGATTACGCTATCAAAGTCAATCAATGGGTTTGACGGTAAGTTGAGCGGGGTTCTGGGCGCAACAATATCTTT
AAAAAAATTTTCAACCCTTGTCAGTGATATGTTGAATGAAGACAATGTCTTATCATTTATGGTTGATAGCAAAGGAAAGT
TAATTGCCCACTATGACCATGATATGGTAATTGAAGGTAAGGACTTTGCACAGGTAATTAACATTGATAACATAAATAAA
ACAAGGGCCGATAACCTTCAATATACCTTTAACCAGACCGAGTATCTGGGATCATATGTTCCACTTCCTTTTATTGATGG
TACTATTATTGTATCGGTGCCCGTAAAACAAGTATTTTCTGGATTGAACAGGATTCAAAGGAAAATGGTGATAATTGAAT
TAACTATTCTCTTTATTTTAGTTCTGGCAGTATACATTGTAATAAGAAGATATCTACTGCAACCCATTTCTTTTTTCACA
AATAACATCCAGAGGGTTGCCCGGGGTGATTTAACGGTTAAATTTGATCTTAAACGGTCAGATGAGATTGGACAGTTAAC
AAAGGTATTTAACAGTATGGTAACACAGTTGAAAAAAATTATTATATCCATTAAAGATGCAGCTAAAATGGTAGGTGGTT
CCTCACACAACCTGAAAGATAATTCCCTACAGGTAGGTAATATGACAGACCAGGTGTTGTCATCAATTGAAGAGCTGGTA
TCCGGCTCAGACGAACAGGCCAACAATATTGAAGATGTAAATAAGCAAATTCAGAACCTGGCTGAGGAGCTGAGCCTTGT
TAATGAGTCAAACCAGATGGTCAGAAAGCTTGCAGGCAGTATGAACCTTGCTTCAGACAGGGGAAGCAAGGAAATTAAGA
GGGTAAAAGAACAGATGGATAAGATAAAAGATACTATTCATAAAGCTGCCCGTGGTTTTACTTACCTGGAATCTGCATCG
GAAGAAATAGATGATATTTTAAATTTAATAAATAATATAGCAGAACAGACAAACTTGCTGGCATTAAATGCTGCCATTGA
GGCTGCAAGGGCAGGAGATGCAGGCCGTGGTTTTAGCGTAGTTGCTGAAGAAATACGGGAACTTGCAGTCGAATCGGTAA
AATCAGCAGACAGGATACGTGATTTAATAACCGATATTAAACAGGAAACAAAGGCAGCAAGTAAGAGAATGCAGGAAGGC
ACAGAAGAAGTAAATAAAGGGGAGGCAGTTGTTAATTCTGCCCGCGAGGCTTTTGGTGATATAAGTCAACTAGTTAAAAA
TGTAAACAATGGATTTGAAAAGTCTAATGAGGCTCTAATGAAAGCAAACAATAATAGTAAAAGGATAGTAGAAAATGTTC
AAAATATAGCAGGTATATCTGAAGAGATATCAGCAAGCTCACAGGAAGTAGCAGCAGCAAGTGAAGAGCAAAAGAGTTCA
ATTGATAATATAATTTCACTGGCAGATGAACTGGCCAGCATGGCAGAAAACTTAAACAAATCAATTGATCGATTTAACAT
TTAG

Upstream 100 bases:

>100_bases
AGCACATTGTAGAAGTAATTATGGGCTGAAAGTATACCTTTGTTCTCTTCTTTAACAGTATTATCAGTGTCAAAAAACTT
AGTTAAAGAAGGGGGAGACA

Downstream 100 bases:

>100_bases
TTAATGACAAATTTATATAACCATTTTTTTAAAGTTAGTGTAAAATAACTTTGGTATAGAAAGATAACGGAGCCAAAGAT
ACCGGAGGATAGATGAGGGA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 667; Mature: 667

Protein sequence:

>667_residues
MKSKKKTNFRLRSSLTIKVIGVVFLVVVILVLFFGVTINSLVSEEITSLVQERNFGMACSIQSEVDAFIKETVNMFELTS
KQDIVRAGSRFPMMDLFNKITADYPQFVSMYFASVKGEIIHFPVVEFSPDYDPVQEEWYKKAVTTEGLVIGNLKKNKNDG
YPVITLSKSINGFDGKLSGVLGATISLKKFSTLVSDMLNEDNVLSFMVDSKGKLIAHYDHDMVIEGKDFAQVINIDNINK
TRADNLQYTFNQTEYLGSYVPLPFIDGTIIVSVPVKQVFSGLNRIQRKMVIIELTILFILVLAVYIVIRRYLLQPISFFT
NNIQRVARGDLTVKFDLKRSDEIGQLTKVFNSMVTQLKKIIISIKDAAKMVGGSSHNLKDNSLQVGNMTDQVLSSIEELV
SGSDEQANNIEDVNKQIQNLAEELSLVNESNQMVRKLAGSMNLASDRGSKEIKRVKEQMDKIKDTIHKAARGFTYLESAS
EEIDDILNLINNIAEQTNLLALNAAIEAARAGDAGRGFSVVAEEIRELAVESVKSADRIRDLITDIKQETKAASKRMQEG
TEEVNKGEAVVNSAREAFGDISQLVKNVNNGFEKSNEALMKANNNSKRIVENVQNIAGISEEISASSQEVAAASEEQKSS
IDNIISLADELASMAENLNKSIDRFNI

Sequences:

>Translated_667_residues
MKSKKKTNFRLRSSLTIKVIGVVFLVVVILVLFFGVTINSLVSEEITSLVQERNFGMACSIQSEVDAFIKETVNMFELTS
KQDIVRAGSRFPMMDLFNKITADYPQFVSMYFASVKGEIIHFPVVEFSPDYDPVQEEWYKKAVTTEGLVIGNLKKNKNDG
YPVITLSKSINGFDGKLSGVLGATISLKKFSTLVSDMLNEDNVLSFMVDSKGKLIAHYDHDMVIEGKDFAQVINIDNINK
TRADNLQYTFNQTEYLGSYVPLPFIDGTIIVSVPVKQVFSGLNRIQRKMVIIELTILFILVLAVYIVIRRYLLQPISFFT
NNIQRVARGDLTVKFDLKRSDEIGQLTKVFNSMVTQLKKIIISIKDAAKMVGGSSHNLKDNSLQVGNMTDQVLSSIEELV
SGSDEQANNIEDVNKQIQNLAEELSLVNESNQMVRKLAGSMNLASDRGSKEIKRVKEQMDKIKDTIHKAARGFTYLESAS
EEIDDILNLINNIAEQTNLLALNAAIEAARAGDAGRGFSVVAEEIRELAVESVKSADRIRDLITDIKQETKAASKRMQEG
TEEVNKGEAVVNSAREAFGDISQLVKNVNNGFEKSNEALMKANNNSKRIVENVQNIAGISEEISASSQEVAAASEEQKSS
IDNIISLADELASMAENLNKSIDRFNI
>Mature_667_residues
MKSKKKTNFRLRSSLTIKVIGVVFLVVVILVLFFGVTINSLVSEEITSLVQERNFGMACSIQSEVDAFIKETVNMFELTS
KQDIVRAGSRFPMMDLFNKITADYPQFVSMYFASVKGEIIHFPVVEFSPDYDPVQEEWYKKAVTTEGLVIGNLKKNKNDG
YPVITLSKSINGFDGKLSGVLGATISLKKFSTLVSDMLNEDNVLSFMVDSKGKLIAHYDHDMVIEGKDFAQVINIDNINK
TRADNLQYTFNQTEYLGSYVPLPFIDGTIIVSVPVKQVFSGLNRIQRKMVIIELTILFILVLAVYIVIRRYLLQPISFFT
NNIQRVARGDLTVKFDLKRSDEIGQLTKVFNSMVTQLKKIIISIKDAAKMVGGSSHNLKDNSLQVGNMTDQVLSSIEELV
SGSDEQANNIEDVNKQIQNLAEELSLVNESNQMVRKLAGSMNLASDRGSKEIKRVKEQMDKIKDTIHKAARGFTYLESAS
EEIDDILNLINNIAEQTNLLALNAAIEAARAGDAGRGFSVVAEEIRELAVESVKSADRIRDLITDIKQETKAASKRMQEG
TEEVNKGEAVVNSAREAFGDISQLVKNVNNGFEKSNEALMKANNNSKRIVENVQNIAGISEEISASSQEVAAASEEQKSS
IDNIISLADELASMAENLNKSIDRFNI

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=298, Percent_Identity=28.8590604026846, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1787690, Length=346, Percent_Identity=24.8554913294798, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788195, Length=286, Percent_Identity=27.972027972028, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1789453, Length=360, Percent_Identity=26.3888888888889, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788194, Length=356, Percent_Identity=25.2808988764045, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 74075; Mature: 74075

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKKKTNFRLRSSLTIKVIGVVFLVVVILVLFFGVTINSLVSEEITSLVQERNFGMACS
CCCCCCCCEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
IQSEVDAFIKETVNMFELTSKQDIVRAGSRFPMMDLFNKITADYPQFVSMYFASVKGEII
CHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCEE
HFPVVEFSPDYDPVQEEWYKKAVTTEGLVIGNLKKNKNDGYPVITLSKSINGFDGKLSGV
EEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCHHHHH
LGATISLKKFSTLVSDMLNEDNVLSFMVDSKGKLIAHYDHDMVIEGKDFAQVINIDNINK
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCEEECCCHHHHHHCCCCCCC
TRADNLQYTFNQTEYLGSYVPLPFIDGTIIVSVPVKQVFSGLNRIQRKMVIIELTILFIL
CCCCCCEEEECHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAVYIVIRRYLLQPISFFTNNIQRVARGDLTVKFDLKRSDEIGQLTKVFNSMVTQLKKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
IISIKDAAKMVGGSSHNLKDNSLQVGNMTDQVLSSIEELVSGSDEQANNIEDVNKQIQNL
HHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
AEELSLVNESNQMVRKLAGSMNLASDRGSKEIKRVKEQMDKIKDTIHKAARGFTYLESAS
HHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
EEIDDILNLINNIAEQTNLLALNAAIEAARAGDAGRGFSVVAEEIRELAVESVKSADRIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLITDIKQETKAASKRMQEGTEEVNKGEAVVNSAREAFGDISQLVKNVNNGFEKSNEALM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHH
KANNNSKRIVENVQNIAGISEEISASSQEVAAASEEQKSSIDNIISLADELASMAENLNK
HCCCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIDRFNI
HHHHCCC
>Mature Secondary Structure
MKSKKKTNFRLRSSLTIKVIGVVFLVVVILVLFFGVTINSLVSEEITSLVQERNFGMACS
CCCCCCCCEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
IQSEVDAFIKETVNMFELTSKQDIVRAGSRFPMMDLFNKITADYPQFVSMYFASVKGEII
CHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCEE
HFPVVEFSPDYDPVQEEWYKKAVTTEGLVIGNLKKNKNDGYPVITLSKSINGFDGKLSGV
EEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCHHHHH
LGATISLKKFSTLVSDMLNEDNVLSFMVDSKGKLIAHYDHDMVIEGKDFAQVINIDNINK
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCEEECCCHHHHHHCCCCCCC
TRADNLQYTFNQTEYLGSYVPLPFIDGTIIVSVPVKQVFSGLNRIQRKMVIIELTILFIL
CCCCCCEEEECHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAVYIVIRRYLLQPISFFTNNIQRVARGDLTVKFDLKRSDEIGQLTKVFNSMVTQLKKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
IISIKDAAKMVGGSSHNLKDNSLQVGNMTDQVLSSIEELVSGSDEQANNIEDVNKQIQNL
HHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
AEELSLVNESNQMVRKLAGSMNLASDRGSKEIKRVKEQMDKIKDTIHKAARGFTYLESAS
HHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
EEIDDILNLINNIAEQTNLLALNAAIEAARAGDAGRGFSVVAEEIRELAVESVKSADRIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLITDIKQETKAASKRMQEGTEEVNKGEAVVNSAREAFGDISQLVKNVNNGFEKSNEALM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHH
KANNNSKRIVENVQNIAGISEEISASSQEVAAASEEQKSSIDNIISLADELASMAENLNK
HCCCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIDRFNI
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]