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The map label for this gene is hppA [H]

Identifier: 220932412

GI number: 220932412

Start: 1687724

End: 1689682

Strand: Reverse

Name: hppA [H]

Synonym: Hore_15760

Alternate gene names: 220932412

Gene position: 1689682-1687724 (Counterclockwise)

Preceding gene: 220932413

Following gene: 220932411

Centisome position: 65.54

GC content: 46.71

Gene sequence:

>1959_bases
ATGCAGTTTTATACACCTTTAGCAGGTATCATTGCATTACTTTTTGCCCTGTATCTGGCCGGGAAGGTAAATAAGGCAGA
GCAAGGTACTTCCAAAATGGTCGAACTGTCCCGGGCTATAAATGAAGGGGCTATGGCCTTTTTAGGCAGGGAATACAGGA
TTCTTTCAGTATTTGTAATTATTGTAGCCCTGATAATGATTTTTGTTCCCAGTCTGGGATGGCAGACTGCCGTATCCTTT
ATTTTAGGGGCTATCTTTTCTGCTCTGGCCGGTTTTGTTGGTATGCAGATTGCAACTACTGCTAATGCCAGGACTACCAA
TGCCGCCAGAACTGGTTTGAATAACGCCCTGGAGATTGCTTTTTCCGGTGGGGCCGTAATGGGAATGTCAGTTGTAGGCC
TGGGTACCCTGGGACTTGGGGTGCTCTACATAATATTCACCGGAAATGTAGACTATATCAGGGGTTTTGCCTTTGGTGCC
AGTTCAATTGCCCTTTTCGCCCGTGTTGGTGGTGGGATTTACACCAAAGCGGCCGATGTCGGGGCTGACCTGGTAGGAAA
GGTGGAAGCAGGTATACCTGAGGATGATCCGAGGAACCCGGCCGTTATTGCCGACAATGTCGGTGACAATGTCGGTGATG
TGGCCGGTATGGGTGCTGACCTTTTTGAATCTTATGTTGGTTCTATTGTTGCCGCTATGGCTCTCGGTAGTCTTTTCAGT
ACCCAGGTAACGGAACATGTTATTTTACCATTACTGGTAGCTGCCATAGGTATTATTGCTTCAATCATTAGTACCCGTTT
TGTTAAGGCAAAAGAAGGCGGTAATCCAGCTAAAGCCCTGGAAAGGGGAACTATTATAAGTGGTATCCTGACCTTGATTG
GTTCTTACTTCCTGGTAAACGGCCTTATCGGTGATTTAGGTGTTTTCTGGGCCGTTGTTGCCGGGCTTCTGGCCGGTATT
TTAATCGGACGGATTACCGAATACTATACCTCTGACCACTATAAACCGGTTCAGAGTATAGCCGATCAATCCCAGACCGG
TACTGCTACCAATATCATTGGTGGTCTGGCTGTTGGTATGAAGAGTACTGTTCTTCCCATTATTGTAATTGCAGTAGCTA
TCTTTATTGCCTACTACTTTGGAGAACTTTACGGTATTGCCATTGCTGCCGTTGGTATGCTGGCTACTACCGGAATGACC
CTGGCTGTCGATGCTTATGGTCCTATCTCTGATAACGCCGGTGGTATTGCTGAAATGTCCAACCTGGAACCAGAGGTCCG
TGAAATTACAGACAAGCTCGATTCAGTAGGTAATACAACAGCTGCTATCGGTAAGGGTTTTGCCATTGGTTCTGCTGCAT
TGACCGCTTTATCACTGTTCTCAGCCTTCTCATCTGAAGTAGGGGTTGAGATTAGCCTGACCAACCCGAATGTTATTATT
GGTCTCTTTATCGGAGCTATGCTGCCTTTCTTCTTCTCATCTATCACCATGCAGGCTGTTGGTAGGGCTGCTTTCCAGAT
GATAGAGGAAGTTAGAAGGCAGTTTAAAGAGATACCGGGTATTATGGAAGGAAAGTCCAAACCGGATTATGCTCGCTGTG
TTGATATCAGTACAGCAGCTGCCTTAAAAGAAATGGTTGTGCCCGGATTAATGGCTGTTATTGTACCCATTGTCATTGGA
CTGTGGAGCGCTGAAGCCCTGGGTGGACTCCTGGCTGGAGCTCTGGCTGCCGGTGTTCTCCTGGCTATTATGATGGCCAA
TGCCGGAGGTGCCTGGGATAATGCCAAAAAGTACATTGAGGCCGGTAACTACGGTGGTAAGGGTACCGATACCCATGCTG
CTGCAGTTGTTGGTGATACTGTAGGTGATCCCTTCAAGGATACCTCTGGACCATCTCTGAATATTTTAATCAAGCTTATG
ACCATTGTGTCACTTGTTTTTGCTCCACTATTTATGTAA

Upstream 100 bases:

>100_bases
TTACCTCAATAGCTGCAGTATTATTTATGATTACATCATTATTGTTAGCCTTTTTTGTATAATCTTAAATAAGACTAAAA
TTGAATAAGGAGGATGTCAA

Downstream 100 bases:

>100_bases
TAACAATTACAATAATAATGCTGAGTAAAACCCTCTAAGTGTCAGGCTTAGGGGGTTTTTTAAAAGATATTTTTGGGAGG
AGGAGTTTTATGAGAGAAGG

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase [H]

Number of amino acids: Translated: 652; Mature: 652

Protein sequence:

>652_residues
MQFYTPLAGIIALLFALYLAGKVNKAEQGTSKMVELSRAINEGAMAFLGREYRILSVFVIIVALIMIFVPSLGWQTAVSF
ILGAIFSALAGFVGMQIATTANARTTNAARTGLNNALEIAFSGGAVMGMSVVGLGTLGLGVLYIIFTGNVDYIRGFAFGA
SSIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSIVAAMALGSLFS
TQVTEHVILPLLVAAIGIIASIISTRFVKAKEGGNPAKALERGTIISGILTLIGSYFLVNGLIGDLGVFWAVVAGLLAGI
LIGRITEYYTSDHYKPVQSIADQSQTGTATNIIGGLAVGMKSTVLPIIVIAVAIFIAYYFGELYGIAIAAVGMLATTGMT
LAVDAYGPISDNAGGIAEMSNLEPEVREITDKLDSVGNTTAAIGKGFAIGSAALTALSLFSAFSSEVGVEISLTNPNVII
GLFIGAMLPFFFSSITMQAVGRAAFQMIEEVRRQFKEIPGIMEGKSKPDYARCVDISTAAALKEMVVPGLMAVIVPIVIG
LWSAEALGGLLAGALAAGVLLAIMMANAGGAWDNAKKYIEAGNYGGKGTDTHAAAVVGDTVGDPFKDTSGPSLNILIKLM
TIVSLVFAPLFM

Sequences:

>Translated_652_residues
MQFYTPLAGIIALLFALYLAGKVNKAEQGTSKMVELSRAINEGAMAFLGREYRILSVFVIIVALIMIFVPSLGWQTAVSF
ILGAIFSALAGFVGMQIATTANARTTNAARTGLNNALEIAFSGGAVMGMSVVGLGTLGLGVLYIIFTGNVDYIRGFAFGA
SSIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSIVAAMALGSLFS
TQVTEHVILPLLVAAIGIIASIISTRFVKAKEGGNPAKALERGTIISGILTLIGSYFLVNGLIGDLGVFWAVVAGLLAGI
LIGRITEYYTSDHYKPVQSIADQSQTGTATNIIGGLAVGMKSTVLPIIVIAVAIFIAYYFGELYGIAIAAVGMLATTGMT
LAVDAYGPISDNAGGIAEMSNLEPEVREITDKLDSVGNTTAAIGKGFAIGSAALTALSLFSAFSSEVGVEISLTNPNVII
GLFIGAMLPFFFSSITMQAVGRAAFQMIEEVRRQFKEIPGIMEGKSKPDYARCVDISTAAALKEMVVPGLMAVIVPIVIG
LWSAEALGGLLAGALAAGVLLAIMMANAGGAWDNAKKYIEAGNYGGKGTDTHAAAVVGDTVGDPFKDTSGPSLNILIKLM
TIVSLVFAPLFM
>Mature_652_residues
MQFYTPLAGIIALLFALYLAGKVNKAEQGTSKMVELSRAINEGAMAFLGREYRILSVFVIIVALIMIFVPSLGWQTAVSF
ILGAIFSALAGFVGMQIATTANARTTNAARTGLNNALEIAFSGGAVMGMSVVGLGTLGLGVLYIIFTGNVDYIRGFAFGA
SSIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSIVAAMALGSLFS
TQVTEHVILPLLVAAIGIIASIISTRFVKAKEGGNPAKALERGTIISGILTLIGSYFLVNGLIGDLGVFWAVVAGLLAGI
LIGRITEYYTSDHYKPVQSIADQSQTGTATNIIGGLAVGMKSTVLPIIVIAVAIFIAYYFGELYGIAIAAVGMLATTGMT
LAVDAYGPISDNAGGIAEMSNLEPEVREITDKLDSVGNTTAAIGKGFAIGSAALTALSLFSAFSSEVGVEISLTNPNVII
GLFIGAMLPFFFSSITMQAVGRAAFQMIEEVRRQFKEIPGIMEGKSKPDYARCVDISTAAALKEMVVPGLMAVIVPIVIG
LWSAEALGGLLAGALAAGVLLAIMMANAGGAWDNAKKYIEAGNYGGKGTDTHAAAVVGDTVGDPFKDTSGPSLNILIKLM
TIVSLVFAPLFM

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 67304; Mature: 67304

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFYTPLAGIIALLFALYLAGKVNKAEQGTSKMVELSRAINEGAMAFLGREYRILSVFVI
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IVALIMIFVPSLGWQTAVSFILGAIFSALAGFVGMQIATTANARTTNAARTGLNNALEIA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHCCCHHEEEE
FSGGAVMGMSVVGLGTLGLGVLYIIFTGNVDYIRGFAFGASSIALFARVGGGIYTKAADV
ECCCHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHH
GADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSIVAAMALGSLFS
CHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
TQVTEHVILPLLVAAIGIIASIISTRFVKAKEGGNPAKALERGTIISGILTLIGSYFLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLIGDLGVFWAVVAGLLAGILIGRITEYYTSDHYKPVQSIADQSQTGTATNIIGGLAVGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHH
KSTVLPIIVIAVAIFIAYYFGELYGIAIAAVGMLATTGMTLAVDAYGPISDNAGGIAEMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHH
NLEPEVREITDKLDSVGNTTAAIGKGFAIGSAALTALSLFSAFSSEVGVEISLTNPNVII
CCCHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHH
GLFIGAMLPFFFSSITMQAVGRAAFQMIEEVRRQFKEIPGIMEGKSKPDYARCVDISTAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHH
ALKEMVVPGLMAVIVPIVIGLWSAEALGGLLAGALAAGVLLAIMMANAGGAWDNAKKYIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AGNYGGKGTDTHAAAVVGDTVGDPFKDTSGPSLNILIKLMTIVSLVFAPLFM
CCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFYTPLAGIIALLFALYLAGKVNKAEQGTSKMVELSRAINEGAMAFLGREYRILSVFVI
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IVALIMIFVPSLGWQTAVSFILGAIFSALAGFVGMQIATTANARTTNAARTGLNNALEIA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHCCCHHEEEE
FSGGAVMGMSVVGLGTLGLGVLYIIFTGNVDYIRGFAFGASSIALFARVGGGIYTKAADV
ECCCHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHH
GADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSIVAAMALGSLFS
CHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
TQVTEHVILPLLVAAIGIIASIISTRFVKAKEGGNPAKALERGTIISGILTLIGSYFLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLIGDLGVFWAVVAGLLAGILIGRITEYYTSDHYKPVQSIADQSQTGTATNIIGGLAVGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHH
KSTVLPIIVIAVAIFIAYYFGELYGIAIAAVGMLATTGMTLAVDAYGPISDNAGGIAEMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHH
NLEPEVREITDKLDSVGNTTAAIGKGFAIGSAALTALSLFSAFSSEVGVEISLTNPNVII
CCCHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHH
GLFIGAMLPFFFSSITMQAVGRAAFQMIEEVRRQFKEIPGIMEGKSKPDYARCVDISTAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHH
ALKEMVVPGLMAVIVPIVIGLWSAEALGGLLAGALAAGVLLAIMMANAGGAWDNAKKYIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AGNYGGKGTDTHAAAVVGDTVGDPFKDTSGPSLNILIKLMTIVSLVFAPLFM
CCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA