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The map label for this gene is ccpA [H]

Identifier: 220932394

GI number: 220932394

Start: 1670239

End: 1671249

Strand: Reverse

Name: ccpA [H]

Synonym: Hore_15580

Alternate gene names: 220932394

Gene position: 1671249-1670239 (Counterclockwise)

Preceding gene: 220932395

Following gene: 220932393

Centisome position: 64.82

GC content: 38.38

Gene sequence:

>1011_bases
ATGGGACTTACTATTAAAGATATTGCCCAAAAAGCAGGTGTGTCTACAGCTACTGTTTCCAGAGTTCTTAATAACAGTAA
ACCGGTTAGCCCACAACTTAAGAAAAAAGTTTTAAAAGTAGTAGAAGAAACGGGTTACCGGCCCAATGCCCTGGCCCGGG
GTTTAATAAAAAAACATACTGCTTTAATTGGTGTTATTATACCGGATGTTGCTAATCTAAATTTTGCCGAAATGATTAAG
GGGATAGAACAGGTTGCTGATGAAAACAATTTTGATATCATTCTATCCAGTTCCGGGGCTAATGTCGATAAAGAGTTAGA
AATATTTGATGTATTTATAGAAAAACAGCTGGATGGGATTATTTTTTCCGGTGTTTTCTTTACTGACAGACATAAAGAGT
TTTTTAATAAGTATAATATCCCGACTGTTATTGTTGGTCAAAATTTCCCCGGTGTCGAACTTCCATCAGTAACTATAAAT
AATTTTCAGGCTGCCTATGAAGCTACTTCATATCTAATAGAACTGGGACATCGGAGGATTGGAATGATAACCGGTCCTTT
AAAAGATATTGCAGCCGGGCTTGATAGATACCGTGGTTTCAGTGCAGCTTTAAAGGAATATAAGGTCAAAGAAATTGAGG
AATATGTTGTTGAAGGTGATTTTAATATAGATAGTGGATACCGGTGTATGGAGGATATTCTTACCGGGAAAGAGGTACCA
CCAACAGCTATTTTTGCAGCTTCAGACAAGATCGCTATTGGAGCGATGAATTGCTGTTATGATAAAGGTTATAAAGTTCC
TGACGATATATCGATTATCGGGTTTGATGATACAGAGGTAGCCTCGGTTGTAAGACCAAGTTTAACCACTATTCATCAAA
ACCACCAGGAGATAGGTTCCACCACTGCTCAGCTTTTAATTGACAGGATTAAAGGTAGACATAACCGGGCTATCAATGTG
CAGCTGCCGTACAGGCTTATAGAGAGGGAAAGCACCAGGAAAATAAGATGA

Upstream 100 bases:

>100_bases
TTTTAAAGGTGGTATATAGTGCCAGATGTTTTTGCAATTATTTTTTTAGTCCCCGGGAAAACCTTTACATAATACTAATA
TAAAGTAAGGTGAGTGAGTA

Downstream 100 bases:

>100_bases
TTTTATTAACCGATATGATATTTTTCCAGGAGGGATTAAAATGGATGGAGCAATAATTGAACTAAACGGCAACTGGCTTA
TCAAACATGACCCTGAAGAT

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MGLTIKDIAQKAGVSTATVSRVLNNSKPVSPQLKKKVLKVVEETGYRPNALARGLIKKHTALIGVIIPDVANLNFAEMIK
GIEQVADENNFDIILSSSGANVDKELEIFDVFIEKQLDGIIFSGVFFTDRHKEFFNKYNIPTVIVGQNFPGVELPSVTIN
NFQAAYEATSYLIELGHRRIGMITGPLKDIAAGLDRYRGFSAALKEYKVKEIEEYVVEGDFNIDSGYRCMEDILTGKEVP
PTAIFAASDKIAIGAMNCCYDKGYKVPDDISIIGFDDTEVASVVRPSLTTIHQNHQEIGSTTAQLLIDRIKGRHNRAINV
QLPYRLIERESTRKIR

Sequences:

>Translated_336_residues
MGLTIKDIAQKAGVSTATVSRVLNNSKPVSPQLKKKVLKVVEETGYRPNALARGLIKKHTALIGVIIPDVANLNFAEMIK
GIEQVADENNFDIILSSSGANVDKELEIFDVFIEKQLDGIIFSGVFFTDRHKEFFNKYNIPTVIVGQNFPGVELPSVTIN
NFQAAYEATSYLIELGHRRIGMITGPLKDIAAGLDRYRGFSAALKEYKVKEIEEYVVEGDFNIDSGYRCMEDILTGKEVP
PTAIFAASDKIAIGAMNCCYDKGYKVPDDISIIGFDDTEVASVVRPSLTTIHQNHQEIGSTTAQLLIDRIKGRHNRAINV
QLPYRLIERESTRKIR
>Mature_335_residues
GLTIKDIAQKAGVSTATVSRVLNNSKPVSPQLKKKVLKVVEETGYRPNALARGLIKKHTALIGVIIPDVANLNFAEMIKG
IEQVADENNFDIILSSSGANVDKELEIFDVFIEKQLDGIIFSGVFFTDRHKEFFNKYNIPTVIVGQNFPGVELPSVTINN
FQAAYEATSYLIELGHRRIGMITGPLKDIAAGLDRYRGFSAALKEYKVKEIEEYVVEGDFNIDSGYRCMEDILTGKEVPP
TAIFAASDKIAIGAMNCCYDKGYKVPDDISIIGFDDTEVASVVRPSLTTIHQNHQEIGSTTAQLLIDRIKGRHNRAINVQ
LPYRLIERESTRKIR

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=334, Percent_Identity=36.8263473053892, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1787948, Length=330, Percent_Identity=35.1515151515151, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI1790194, Length=329, Percent_Identity=33.7386018237082, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI1788474, Length=334, Percent_Identity=33.2335329341317, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789202, Length=288, Percent_Identity=33.6805555555556, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789068, Length=294, Percent_Identity=29.2517006802721, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1787580, Length=323, Percent_Identity=30.3405572755418, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI48994940, Length=310, Percent_Identity=29.3548387096774, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786540, Length=338, Percent_Identity=29.8816568047337, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1790715, Length=325, Percent_Identity=28.9230769230769, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786268, Length=324, Percent_Identity=24.0740740740741, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790689, Length=311, Percent_Identity=25.08038585209, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787906, Length=337, Percent_Identity=24.0356083086053, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789456, Length=343, Percent_Identity=28.2798833819242, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37310; Mature: 37179

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLTIKDIAQKAGVSTATVSRVLNNSKPVSPQLKKKVLKVVEETGYRPNALARGLIKKHT
CCCCHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ALIGVIIPDVANLNFAEMIKGIEQVADENNFDIILSSSGANVDKELEIFDVFIEKQLDGI
HHEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCE
IFSGVFFTDRHKEFFNKYNIPTVIVGQNFPGVELPSVTINNFQAAYEATSYLIELGHRRI
EEECEEEEHHHHHHHHHCCCCEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCE
GMITGPLKDIAAGLDRYRGFSAALKEYKVKEIEEYVVEGDFNIDSGYRCMEDILTGKEVP
EEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCC
PTAIFAASDKIAIGAMNCCYDKGYKVPDDISIIGFDDTEVASVVRPSLTTIHQNHQEIGS
CCEEEECCCCEEEEEHHHHHHCCCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHHHHHH
TTAQLLIDRIKGRHNRAINVQLPYRLIERESTRKIR
HHHHHHHHHHCCCCCCEEEEECCHHHHCCCHHCCCC
>Mature Secondary Structure 
GLTIKDIAQKAGVSTATVSRVLNNSKPVSPQLKKKVLKVVEETGYRPNALARGLIKKHT
CCCHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ALIGVIIPDVANLNFAEMIKGIEQVADENNFDIILSSSGANVDKELEIFDVFIEKQLDGI
HHEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCE
IFSGVFFTDRHKEFFNKYNIPTVIVGQNFPGVELPSVTINNFQAAYEATSYLIELGHRRI
EEECEEEEHHHHHHHHHCCCCEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCE
GMITGPLKDIAAGLDRYRGFSAALKEYKVKEIEEYVVEGDFNIDSGYRCMEDILTGKEVP
EEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCC
PTAIFAASDKIAIGAMNCCYDKGYKVPDDISIIGFDDTEVASVVRPSLTTIHQNHQEIGS
CCEEEECCCCEEEEEHHHHHHCCCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHHHHHH
TTAQLLIDRIKGRHNRAINVQLPYRLIERESTRKIR
HHHHHHHHHHCCCCCCEEEEECCHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]