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The map label for this gene is minD [H]

Identifier: 220932255

GI number: 220932255

Start: 1506892

End: 1507689

Strand: Reverse

Name: minD [H]

Synonym: Hore_14190

Alternate gene names: 220932255

Gene position: 1507689-1506892 (Counterclockwise)

Preceding gene: 220932256

Following gene: 220932254

Centisome position: 58.48

GC content: 40.85

Gene sequence:

>798_bases
GTGGCAGGAAAAGTGATTGTTATAACATCCGGAAAAGGTGGGGTCGGTAAAACGACCACTACAGCAAATTTAGGGACAGC
TCTAGCCATGATGGGGAAGAGGGTCTGTTTAATTGATGCCGATATTGGGTTGAGAAACCTGGATGTTGTTATGGGACTCG
AAAATAGAATTGTTTATGATATAGTGGATGTAGTTGAAGGGAATTGCAGGCTGGAGCAGGCTCTGATCAGGGATAAAAGG
AATAAAAATCTCTTTCTGTTACCGGCTGCCCAGACCAGGGATAAAACAGCTGTAACACCATATCAGATGCAGGAATTGAC
TACAACCCTGAAGGAAGATATGGATTATGTTCTGGTTGACTCACCTGCCGGCATTGAACAGGGTTTTAAAAATGCTATAT
CCGGGGCTGATGATGCCATTATTATTACTACTCCGGAGGTTTCTGCAGTCAGGGATGCTGACAGAATTATTGGACTTCTG
GAAACAGAGGGGTTAAAAAACCCCGAGGTTATAATTAACAGAATCAGGATCGATATGGTTCAAAAAGGTGATATGATGGA
TATTGATGACATGATAGAAATCCTGGCCATAAATTTACTAGGGGTTGTCCCGGAAGATGAAAGTATCGTTATTTCAACAA
ACAAGGGTGAACCCATCGTAATTAAAGCAGATAAATCAAAAGCCGGAGAAGCCTTTATGAATATAGCCCGTCGTATTAAT
GGAGAAGAATTACCATTGATGTCACTTGAGAAGGAAACCCTGATCAAGAAAATTAAAAAGATGGTTGGATTATCATAA

Upstream 100 bases:

>100_bases
ATAAAATCAGGCCGGAGAAAGCCTATATTAAAGGAAGTAATATCATCGTTGAAGAATTAGATTTATAATATTTACAAATT
TACATAAGGAGGAAGCTAAA

Downstream 100 bases:

>100_bases
AGGAGGGAATAGCCATCGACCTGCTGAAAAAAATGGGGTTAAAAGAAGGTGAAGGCCCCAGTAAGGATATCGCAAAAGAG
CGGCTTCAGTTTATATTAAT

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MAGKVIVITSGKGGVGKTTTTANLGTALAMMGKRVCLIDADIGLRNLDVVMGLENRIVYDIVDVVEGNCRLEQALIRDKR
NKNLFLLPAAQTRDKTAVTPYQMQELTTTLKEDMDYVLVDSPAGIEQGFKNAISGADDAIIITTPEVSAVRDADRIIGLL
ETEGLKNPEVIINRIRIDMVQKGDMMDIDDMIEILAINLLGVVPEDESIVISTNKGEPIVIKADKSKAGEAFMNIARRIN
GEELPLMSLEKETLIKKIKKMVGLS

Sequences:

>Translated_265_residues
MAGKVIVITSGKGGVGKTTTTANLGTALAMMGKRVCLIDADIGLRNLDVVMGLENRIVYDIVDVVEGNCRLEQALIRDKR
NKNLFLLPAAQTRDKTAVTPYQMQELTTTLKEDMDYVLVDSPAGIEQGFKNAISGADDAIIITTPEVSAVRDADRIIGLL
ETEGLKNPEVIINRIRIDMVQKGDMMDIDDMIEILAINLLGVVPEDESIVISTNKGEPIVIKADKSKAGEAFMNIARRIN
GEELPLMSLEKETLIKKIKKMVGLS
>Mature_264_residues
AGKVIVITSGKGGVGKTTTTANLGTALAMMGKRVCLIDADIGLRNLDVVMGLENRIVYDIVDVVEGNCRLEQALIRDKRN
KNLFLLPAAQTRDKTAVTPYQMQELTTTLKEDMDYVLVDSPAGIEQGFKNAISGADDAIIITTPEVSAVRDADRIIGLLE
TEGLKNPEVIINRIRIDMVQKGDMMDIDDMIEILAINLLGVVPEDESIVISTNKGEPIVIKADKSKAGEAFMNIARRING
EELPLMSLEKETLIKKIKKMVGLS

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=256, Percent_Identity=22.65625, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787423, Length=258, Percent_Identity=46.5116279069767, Blast_Score=240, Evalue=5e-65,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 28881; Mature: 28750

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGKVIVITSGKGGVGKTTTTANLGTALAMMGKRVCLIDADIGLRNLDVVMGLENRIVYD
CCCEEEEEECCCCCCCCCEECHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCHHHH
IVDVVEGNCRLEQALIRDKRNKNLFLLPAAQTRDKTAVTPYQMQELTTTLKEDMDYVLVD
HHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEE
SPAGIEQGFKNAISGADDAIIITTPEVSAVRDADRIIGLLETEGLKNPEVIINRIRIDMV
CCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHEEHHHCCCCCCHHHHHHHHHEEEE
QKGDMMDIDDMIEILAINLLGVVPEDESIVISTNKGEPIVIKADKSKAGEAFMNIARRIN
CCCCCCCHHHHHHHHHHHHHEECCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCC
GEELPLMSLEKETLIKKIKKMVGLS
CCCCCEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGKVIVITSGKGGVGKTTTTANLGTALAMMGKRVCLIDADIGLRNLDVVMGLENRIVYD
CCEEEEEECCCCCCCCCEECHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCHHHH
IVDVVEGNCRLEQALIRDKRNKNLFLLPAAQTRDKTAVTPYQMQELTTTLKEDMDYVLVD
HHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEE
SPAGIEQGFKNAISGADDAIIITTPEVSAVRDADRIIGLLETEGLKNPEVIINRIRIDMV
CCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHEEHHHCCCCCCHHHHHHHHHEEEE
QKGDMMDIDDMIEILAINLLGVVPEDESIVISTNKGEPIVIKADKSKAGEAFMNIARRIN
CCCCCCCHHHHHHHHHHHHHEECCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCC
GEELPLMSLEKETLIKKIKKMVGLS
CCCCCEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 8459776; 1400224; 9384377 [H]