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The map label for this gene is ahpC [C]

Identifier: 220932133

GI number: 220932133

Start: 1390797

End: 1391447

Strand: Reverse

Name: ahpC [C]

Synonym: Hore_12960

Alternate gene names: 220932133

Gene position: 1391447-1390797 (Counterclockwise)

Preceding gene: 220932134

Following gene: 220932132

Centisome position: 53.97

GC content: 37.48

Gene sequence:

>651_bases
ATGGAAAACATTAATAACATACCATTAATAGGTGATAGGTTTCCTGAAATGGAGGTAAAAACTACTCACGGGGTAAAGAA
TCTTCCAGAGGATTATAAGGGAAAATGGTTTATTCTTTTCAGCCATCCGGCAGATTTCACCCCGGTATGTACAACTGAGT
TTGTTGCTTTTCAAAAAAGATTTGATGAATTTAAAAAAATGGATGCGGAATTAATTGGATTAAGTATTGATCAGGTTTTT
TCCCACATTAAATGGGTGGAATGGATAAATGATAACCTTGATGTTGAAATTAAATTTCCTGTTATTGCAGATGATACCGG
GAGGGTTGCCTCAAAGCTGGGGTTAATTCATCCCAATAAGGGAACCAATACAGTTAGGGCAGTATTTATTGTAGACCCTG
AAGGTATAGTCCGGGCAATCCTTTATTATCCACAGGAACTGGGACGTAATATGGATGAAATTTTAAGGATGGTTAAGGGC
CTTCAGATTTCTGATGATAACAATGTTGCTGTACCTGCTAACTGGCCAGACAATGAACTTATTAACGACCGGGTTATTAT
TGAACCTGCCTCAGATGAAGAAACAGCTAAAAAGCGGCTTAAAGAACACAAATGCTTTGACTGGTGGTTCTGCCATAAAG
AGTTAAAATAA

Upstream 100 bases:

>100_bases
CTTTTTTTTATTTTTTTATTTATTCCTTGACAGGAGTTATTTTTTTGATTATAATAATAGTAACAATTACTATTATTAAA
AATCAAGAGGAGGTATTTTT

Downstream 100 bases:

>100_bases
TTGTTTTTTAAGGCCCGGAGGTAACAGCCTCCGGGTTATTTTATTATAATATGATAAGTTCATAATTGATTTAAACATAT
AAAAATATTAAATTAATACA

Product: Alkyl hydroperoxide reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MENINNIPLIGDRFPEMEVKTTHGVKNLPEDYKGKWFILFSHPADFTPVCTTEFVAFQKRFDEFKKMDAELIGLSIDQVF
SHIKWVEWINDNLDVEIKFPVIADDTGRVASKLGLIHPNKGTNTVRAVFIVDPEGIVRAILYYPQELGRNMDEILRMVKG
LQISDDNNVAVPANWPDNELINDRVIIEPASDEETAKKRLKEHKCFDWWFCHKELK

Sequences:

>Translated_216_residues
MENINNIPLIGDRFPEMEVKTTHGVKNLPEDYKGKWFILFSHPADFTPVCTTEFVAFQKRFDEFKKMDAELIGLSIDQVF
SHIKWVEWINDNLDVEIKFPVIADDTGRVASKLGLIHPNKGTNTVRAVFIVDPEGIVRAILYYPQELGRNMDEILRMVKG
LQISDDNNVAVPANWPDNELINDRVIIEPASDEETAKKRLKEHKCFDWWFCHKELK
>Mature_216_residues
MENINNIPLIGDRFPEMEVKTTHGVKNLPEDYKGKWFILFSHPADFTPVCTTEFVAFQKRFDEFKKMDAELIGLSIDQVF
SHIKWVEWINDNLDVEIKFPVIADDTGRVASKLGLIHPNKGTNTVRAVFIVDPEGIVRAILYYPQELGRNMDEILRMVKG
LQISDDNNVAVPANWPDNELINDRVIIEPASDEETAKKRLKEHKCFDWWFCHKELK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=199, Percent_Identity=40.2010050251256, Blast_Score=128, Evalue=5e-30,
Organism=Homo sapiens, GI32189392, Length=158, Percent_Identity=35.4430379746835, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI5453549, Length=153, Percent_Identity=35.2941176470588, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI4505591, Length=158, Percent_Identity=36.0759493670886, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI32455266, Length=158, Percent_Identity=36.0759493670886, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI32455264, Length=158, Percent_Identity=36.0759493670886, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI5802974, Length=171, Percent_Identity=32.7485380116959, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI32483377, Length=171, Percent_Identity=32.7485380116959, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI33188454, Length=58, Percent_Identity=48.2758620689655, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1786822, Length=151, Percent_Identity=31.1258278145695, Blast_Score=91, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI25153706, Length=202, Percent_Identity=35.1485148514851, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17554494, Length=147, Percent_Identity=36.734693877551, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI193204376, Length=158, Percent_Identity=35.4430379746835, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI32565831, Length=158, Percent_Identity=35.4430379746835, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319407, Length=196, Percent_Identity=40.3061224489796, Blast_Score=135, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6320661, Length=147, Percent_Identity=34.0136054421769, Blast_Score=95, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6323613, Length=147, Percent_Identity=32.6530612244898, Blast_Score=92, Evalue=9e-20,
Organism=Drosophila melanogaster, GI17975518, Length=199, Percent_Identity=39.1959798994975, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24652434, Length=199, Percent_Identity=39.1959798994975, Blast_Score=127, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24652436, Length=199, Percent_Identity=38.6934673366834, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24581278, Length=172, Percent_Identity=40.1162790697674, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17738015, Length=175, Percent_Identity=36.5714285714286, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24656348, Length=147, Percent_Identity=34.6938775510204, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17864676, Length=147, Percent_Identity=34.6938775510204, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17157991, Length=147, Percent_Identity=36.0544217687075, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641739, Length=147, Percent_Identity=36.0544217687075, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357347, Length=156, Percent_Identity=34.6153846153846, Blast_Score=103, Evalue=7e-23,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 25028; Mature: 25028

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENINNIPLIGDRFPEMEVKTTHGVKNLPEDYKGKWFILFSHPADFTPVCTTEFVAFQKR
CCCCCCCCEECCCCCCCEEECCCCCCCCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH
FDEFKKMDAELIGLSIDQVFSHIKWVEWINDNLDVEIKFPVIADDTGRVASKLGLIHPNK
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHCCCCCCC
GTNTVRAVFIVDPEGIVRAILYYPQELGRNMDEILRMVKGLQISDDNNVAVPANWPDNEL
CCCEEEEEEEECCHHHHHHHHHCHHHHCCCHHHHHHHHHCCEECCCCCEEEECCCCCCCC
INDRVIIEPASDEETAKKRLKEHKCFDWWFCHKELK
CCCEEEEECCCCHHHHHHHHHHCCCHHEEEEECCCC
>Mature Secondary Structure
MENINNIPLIGDRFPEMEVKTTHGVKNLPEDYKGKWFILFSHPADFTPVCTTEFVAFQKR
CCCCCCCCEECCCCCCCEEECCCCCCCCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH
FDEFKKMDAELIGLSIDQVFSHIKWVEWINDNLDVEIKFPVIADDTGRVASKLGLIHPNK
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHCCCCCCC
GTNTVRAVFIVDPEGIVRAILYYPQELGRNMDEILRMVKGLQISDDNNVAVPANWPDNEL
CCCEEEEEEEECCHHHHHHHHHCHHHHCCCHHHHHHHHHCCEECCCCCEEEECCCCCCCC
INDRVIIEPASDEETAKKRLKEHKCFDWWFCHKELK
CCCEEEEECCCCHHHHHHHHHHCCCHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]