Click here to switch to the map view.

The map label for this gene is yhcK [H]

Identifier: 220932075

GI number: 220932075

Start: 1329459

End: 1330958

Strand: Reverse

Name: yhcK [H]

Synonym: Hore_12380

Alternate gene names: 220932075

Gene position: 1330958-1329459 (Counterclockwise)

Preceding gene: 220932076

Following gene: 220932074

Centisome position: 51.62

GC content: 32.4

Gene sequence:

>1500_bases
ATGGCCATCAAGAAGGTAAGCAGATATAAGATTATTAAATCAGTATTTGATTTTTTTCTATCATTTGATCATGAGGCATC
AAACCATAAAATTATAAAAGATGTCAATGATTTCTGTTATAAAATGTTGAATGTGAAATATACCGGTCTATATATAGATG
ATGAAGGTAGAAATGAAGTAATAAGTTTGAAGCAGGATATAACCAGGATGGAGTTCAATTCAGAGTTGACAGATAAAATT
AAAAGAGATAATAGAATTTACGGGGGGGAAATAAGTAAAGATTTTACCCTGATTCCGCAGTTTGAAGCAGAAAACAGATT
AAAGTATTTGTTAGTTATTCCTTTAACTAACAAGAATAAACACTTCGGATTTTTGTTTTTTTATGGAACGGATCCACAGA
CCTTTAATGACTTTTCTGTGAAAGTTTTAAAATTGCTTACCAAAGTATTATCCCTTACAATAGGAGAAAAGAAACTTTAC
CGGGAAATGGAGCAGAGGGTTGCCGAACTTATAACCCTTCAAAATGTCAGTAATTTTGTTAATGCAACCCTTGATTTTGA
AAAATTACTGGATGTTTCCCTGGATGCTCTGGTAGGCCTTATTGGGCTGAGAACCTGTTCAATAGTGTTATTTACAGATA
AGCTTTTTGATGACATCTATACCAGGAAACAAAATACCCTGATAGCTTCCCTGGATATGAGTAAAGAAATTGTTTTGGAC
CTATCATCCGGGATTTATAAAGAGTTATCCAGAAAAAAGAAAGTTATTGCCGGTAAAGTATCTTTTGATGATGATTTAAG
TAAAATTATACCCCTTGATAATATTGAAGAGGGTAAAGAAATTGAATATATAATTGTCCCGGTAACCAGAGGTAAGGAAC
TGATAGGGTCTATAAATATTTTTTCAATGGATAAGGGTCATTTACCTATTTTACAACACAGTTTTCTCGAATCTTTTGCC
AACCAGTTCAGTGTGGCTTTACAAAATGCTTTATTATATAAAAAACAGGAAGAAATGGCCAACAGGGATGGTTTAACCGG
GTTATATAACCATGCTTATTTCCAGAACAGGTTACATCTTTTATTAAAACAGGAAAATAAACATCCATTAACCCTCATAA
TTATGGATATTGATAATTTCAAACAGGTTAACGATAGATTTGGACATCTTGTTGGTGATAAAGTTTTGAAAGAACTTGCT
CACCTGTTAAAACATAATTTGAGGGAGGGTGATTTAATAGCAAGATACGGTGGAGAAGAATTTGCTATAATTTTGCCGGA
AACTGAACTGAAACAGGGAGAATTTATAGCTAAAAGATTAAGAAAATTGATATCAGATAATGAAATTGTACTTGATAATA
ATAGATCACTATATATAACAGTAAGTATAGGTGTGGCTCAATATAATAAAAAATGGAGTCAGGAAGAATTTATTGATAAA
GCGGATCAGGCTCTTTATAAAGCAAAGGAAGCCGGTAAAAACAGGGTTACACTTGCTTAA

Upstream 100 bases:

>100_bases
CAGCTATGGTAATCAATTAAAAAAGGCGCTTATTCAAATTTGTTTTTAATAGTGAGAAGAATAGGACTAGATTAGATTAG
TGTGGGCTGGGGGAAATAAA

Downstream 100 bases:

>100_bases
AAATAATTTATGGGGTAATTGTGTTGGATAACTAATTGCCGTTAAAACTTAGTAACAAAAATCGTTGTATTATTTTCAGG
AAAAATTATTATAATATAAA

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MAIKKVSRYKIIKSVFDFFLSFDHEASNHKIIKDVNDFCYKMLNVKYTGLYIDDEGRNEVISLKQDITRMEFNSELTDKI
KRDNRIYGGEISKDFTLIPQFEAENRLKYLLVIPLTNKNKHFGFLFFYGTDPQTFNDFSVKVLKLLTKVLSLTIGEKKLY
REMEQRVAELITLQNVSNFVNATLDFEKLLDVSLDALVGLIGLRTCSIVLFTDKLFDDIYTRKQNTLIASLDMSKEIVLD
LSSGIYKELSRKKKVIAGKVSFDDDLSKIIPLDNIEEGKEIEYIIVPVTRGKELIGSINIFSMDKGHLPILQHSFLESFA
NQFSVALQNALLYKKQEEMANRDGLTGLYNHAYFQNRLHLLLKQENKHPLTLIIMDIDNFKQVNDRFGHLVGDKVLKELA
HLLKHNLREGDLIARYGGEEFAIILPETELKQGEFIAKRLRKLISDNEIVLDNNRSLYITVSIGVAQYNKKWSQEEFIDK
ADQALYKAKEAGKNRVTLA

Sequences:

>Translated_499_residues
MAIKKVSRYKIIKSVFDFFLSFDHEASNHKIIKDVNDFCYKMLNVKYTGLYIDDEGRNEVISLKQDITRMEFNSELTDKI
KRDNRIYGGEISKDFTLIPQFEAENRLKYLLVIPLTNKNKHFGFLFFYGTDPQTFNDFSVKVLKLLTKVLSLTIGEKKLY
REMEQRVAELITLQNVSNFVNATLDFEKLLDVSLDALVGLIGLRTCSIVLFTDKLFDDIYTRKQNTLIASLDMSKEIVLD
LSSGIYKELSRKKKVIAGKVSFDDDLSKIIPLDNIEEGKEIEYIIVPVTRGKELIGSINIFSMDKGHLPILQHSFLESFA
NQFSVALQNALLYKKQEEMANRDGLTGLYNHAYFQNRLHLLLKQENKHPLTLIIMDIDNFKQVNDRFGHLVGDKVLKELA
HLLKHNLREGDLIARYGGEEFAIILPETELKQGEFIAKRLRKLISDNEIVLDNNRSLYITVSIGVAQYNKKWSQEEFIDK
ADQALYKAKEAGKNRVTLA
>Mature_498_residues
AIKKVSRYKIIKSVFDFFLSFDHEASNHKIIKDVNDFCYKMLNVKYTGLYIDDEGRNEVISLKQDITRMEFNSELTDKIK
RDNRIYGGEISKDFTLIPQFEAENRLKYLLVIPLTNKNKHFGFLFFYGTDPQTFNDFSVKVLKLLTKVLSLTIGEKKLYR
EMEQRVAELITLQNVSNFVNATLDFEKLLDVSLDALVGLIGLRTCSIVLFTDKLFDDIYTRKQNTLIASLDMSKEIVLDL
SSGIYKELSRKKKVIAGKVSFDDDLSKIIPLDNIEEGKEIEYIIVPVTRGKELIGSINIFSMDKGHLPILQHSFLESFAN
QFSVALQNALLYKKQEEMANRDGLTGLYNHAYFQNRLHLLLKQENKHPLTLIIMDIDNFKQVNDRFGHLVGDKVLKELAH
LLKHNLREGDLIARYGGEEFAIILPETELKQGEFIAKRLRKLISDNEIVLDNNRSLYITVSIGVAQYNKKWSQEEFIDKA
DQALYKAKEAGKNRVTLA

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87082007, Length=174, Percent_Identity=37.3563218390805, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1787262, Length=172, Percent_Identity=38.3720930232558, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1786584, Length=169, Percent_Identity=38.4615384615385, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788381, Length=164, Percent_Identity=36.5853658536585, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693134, Length=162, Percent_Identity=35.8024691358025, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI87081881, Length=174, Percent_Identity=37.3563218390805, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1787802, Length=181, Percent_Identity=33.7016574585635, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787816, Length=246, Percent_Identity=30.0813008130081, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788085, Length=169, Percent_Identity=32.5443786982249, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1787541, Length=162, Percent_Identity=31.4814814814815, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787056, Length=186, Percent_Identity=30.1075268817204, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788956, Length=176, Percent_Identity=34.0909090909091, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081974, Length=113, Percent_Identity=35.3982300884956, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87081977, Length=150, Percent_Identity=31.3333333333333, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 57521; Mature: 57390

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKKVSRYKIIKSVFDFFLSFDHEASNHKIIKDVNDFCYKMLNVKYTGLYIDDEGRNEV
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCEEEEEEEECCCCCCHH
ISLKQDITRMEFNSELTDKIKRDNRIYGGEISKDFTLIPQFEAENRLKYLLVIPLTNKNK
HHHHHHHHHHHCCCHHHHHHHHCCCEECCCCCCCEEEEECCCCCCCEEEEEEEEECCCCC
HFGFLFFYGTDPQTFNDFSVKVLKLLTKVLSLTIGEKKLYREMEQRVAELITLQNVSNFV
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
NATLDFEKLLDVSLDALVGLIGLRTCSIVLFTDKLFDDIYTRKQNTLIASLDMSKEIVLD
HCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHCCCCCEEEEECCCCHHEEE
LSSGIYKELSRKKKVIAGKVSFDDDLSKIIPLDNIEEGKEIEYIIVPVTRGKELIGSINI
HHHHHHHHHHHHHHEEEEECCCCCCHHHHCCCCCCCCCCCEEEEEEEECCCHHHHCCEEE
FSMDKGHLPILQHSFLESFANQFSVALQNALLYKKQEEMANRDGLTGLYNHAYFQNRLHL
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHE
LLKQENKHPLTLIIMDIDNFKQVNDRFGHLVGDKVLKELAHLLKHNLREGDLIARYGGEE
EEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCE
FAIILPETELKQGEFIAKRLRKLISDNEIVLDNNRSLYITVSIGVAQYNKKWSQEEFIDK
EEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCEEEEEEEEEHHHHCCCCCHHHHHHH
ADQALYKAKEAGKNRVTLA
HHHHHHHHHHCCCCCEEEC
>Mature Secondary Structure 
AIKKVSRYKIIKSVFDFFLSFDHEASNHKIIKDVNDFCYKMLNVKYTGLYIDDEGRNEV
CCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCEEEEEEEECCCCCCHH
ISLKQDITRMEFNSELTDKIKRDNRIYGGEISKDFTLIPQFEAENRLKYLLVIPLTNKNK
HHHHHHHHHHHCCCHHHHHHHHCCCEECCCCCCCEEEEECCCCCCCEEEEEEEEECCCCC
HFGFLFFYGTDPQTFNDFSVKVLKLLTKVLSLTIGEKKLYREMEQRVAELITLQNVSNFV
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
NATLDFEKLLDVSLDALVGLIGLRTCSIVLFTDKLFDDIYTRKQNTLIASLDMSKEIVLD
HCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHCCCCCEEEEECCCCHHEEE
LSSGIYKELSRKKKVIAGKVSFDDDLSKIIPLDNIEEGKEIEYIIVPVTRGKELIGSINI
HHHHHHHHHHHHHHEEEEECCCCCCHHHHCCCCCCCCCCCEEEEEEEECCCHHHHCCEEE
FSMDKGHLPILQHSFLESFANQFSVALQNALLYKKQEEMANRDGLTGLYNHAYFQNRLHL
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHE
LLKQENKHPLTLIIMDIDNFKQVNDRFGHLVGDKVLKELAHLLKHNLREGDLIARYGGEE
EEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCE
FAIILPETELKQGEFIAKRLRKLISDNEIVLDNNRSLYITVSIGVAQYNKKWSQEEFIDK
EEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCEEEEEEEEEHHHHCCCCCHHHHHHH
ADQALYKAKEAGKNRVTLA
HHHHHHHHHHCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]