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The map label for this gene is hisK [H]

Identifier: 220931991

GI number: 220931991

Start: 1243368

End: 1244147

Strand: Reverse

Name: hisK [H]

Synonym: Hore_11520

Alternate gene names: 220931991

Gene position: 1244147-1243368 (Counterclockwise)

Preceding gene: 220931994

Following gene: 220931990

Centisome position: 48.26

GC content: 32.82

Gene sequence:

>780_bases
ATGTATTTAGTTGATTATCATACCCACCCCTATGCTCATGGTGAAGATAATGTTAAACCTGCCCATAATTTTGATTACTT
AAAGAAATTTTTAAAAATGGCAAAGGTGGCTGAAGTAAAGGAGATAGGGTTTTCAGATCATGATCGGTTTATCGATGAAA
TTAACTGGGATAATTTATTAAAATTTAAAGAGAAAAATAAAAATAATGTTAAATTGGGCCTGGAAATTGATTTTAGTCCG
GACAGAATTGATGACATAAAAAAAATAATTAAAGAATACCCACTGGATTATACAATAGGGTCAGTACACCGGATTGGTGA
CTGGGAGGTAGATCATCCTGTTTATATTGAAGAATACCATAAACGTGATTTAATTACAGTTTACAAACAGTATTTCGAAC
TGGTTAAAGAAGCCGCTTCCAGTGGTCTATTTAATATAATCGGTCATATAGATCTGATTAAAATTTTTAATATCATACCC
CCAGGAATAAATATGCTTGAAATGGTAGAACCCGCCCTTGAAGTAATAAAAAAACGGGGCCTTGCTATAGAAATAAATAC
AAATGGATTAAATAAACCGGTCAATGAAATCTACCCGTCACTATCAATTATAAAAAGAATTGTAAAGATGGGTATTCCAC
TAACCCTGGGCTCTGATGCCCATGGACCAAAACGGGTGGGTGAAAATTTAAAACTGATGGGAAATTTGTTACTTAAAAAT
GGCTGTCAAAGGATTGCTACCTTTACTGAGAAAAAAATGAAAATGATCAGAATTAAATAA

Upstream 100 bases:

>100_bases
CAAACTTTATTCCATAATTAATTAAAGTATAAATAATTAAAGTATAATCTGTTAAGATGGTAAGAAATAATTATAAACCA
TATATAAAAGGAGTGTTTTC

Downstream 100 bases:

>100_bases
ACCCTTTAAAGCCCCCCTTGACGGGGGCTTTTTATTTCACAAAAAAATACCTATTACATAATATAAAAATGTATGATGAA
TAAAAACTACAGGAGGTGGC

Product: histidinol-phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MYLVDYHTHPYAHGEDNVKPAHNFDYLKKFLKMAKVAEVKEIGFSDHDRFIDEINWDNLLKFKEKNKNNVKLGLEIDFSP
DRIDDIKKIIKEYPLDYTIGSVHRIGDWEVDHPVYIEEYHKRDLITVYKQYFELVKEAASSGLFNIIGHIDLIKIFNIIP
PGINMLEMVEPALEVIKKRGLAIEINTNGLNKPVNEIYPSLSIIKRIVKMGIPLTLGSDAHGPKRVGENLKLMGNLLLKN
GCQRIATFTEKKMKMIRIK

Sequences:

>Translated_259_residues
MYLVDYHTHPYAHGEDNVKPAHNFDYLKKFLKMAKVAEVKEIGFSDHDRFIDEINWDNLLKFKEKNKNNVKLGLEIDFSP
DRIDDIKKIIKEYPLDYTIGSVHRIGDWEVDHPVYIEEYHKRDLITVYKQYFELVKEAASSGLFNIIGHIDLIKIFNIIP
PGINMLEMVEPALEVIKKRGLAIEINTNGLNKPVNEIYPSLSIIKRIVKMGIPLTLGSDAHGPKRVGENLKLMGNLLLKN
GCQRIATFTEKKMKMIRIK
>Mature_259_residues
MYLVDYHTHPYAHGEDNVKPAHNFDYLKKFLKMAKVAEVKEIGFSDHDRFIDEINWDNLLKFKEKNKNNVKLGLEIDFSP
DRIDDIKKIIKEYPLDYTIGSVHRIGDWEVDHPVYIEEYHKRDLITVYKQYFELVKEAASSGLFNIIGHIDLIKIFNIIP
PGINMLEMVEPALEVIKKRGLAIEINTNGLNKPVNEIYPSLSIIKRIVKMGIPLTLGSDAHGPKRVGENLKLMGNLLLKN
GCQRIATFTEKKMKMIRIK

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 29942; Mature: 29942

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLVDYHTHPYAHGEDNVKPAHNFDYLKKFLKMAKVAEVKEIGFSDHDRFIDEINWDNLL
CEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHH
KFKEKNKNNVKLGLEIDFSPDRIDDIKKIIKEYPLDYTIGSVHRIGDWEVDHPVYIEEYH
HHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHH
KRDLITVYKQYFELVKEAASSGLFNIIGHIDLIKIFNIIPPGINMLEMVEPALEVIKKRG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
LAIEINTNGLNKPVNEIYPSLSIIKRIVKMGIPLTLGSDAHGPKRVGENLKLMGNLLLKN
CEEEEECCCCCCCHHHHCCCHHHHHHHHHHCCCEEECCCCCCHHHHCCHHHHHHHHHHHH
GCQRIATFTEKKMKMIRIK
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYLVDYHTHPYAHGEDNVKPAHNFDYLKKFLKMAKVAEVKEIGFSDHDRFIDEINWDNLL
CEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHH
KFKEKNKNNVKLGLEIDFSPDRIDDIKKIIKEYPLDYTIGSVHRIGDWEVDHPVYIEEYH
HHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHH
KRDLITVYKQYFELVKEAASSGLFNIIGHIDLIKIFNIIPPGINMLEMVEPALEVIKKRG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
LAIEINTNGLNKPVNEIYPSLSIIKRIVKMGIPLTLGSDAHGPKRVGENLKLMGNLLLKN
CEEEEECCCCCCCHHHHCCCHHHHHHHHHHCCCEEECCCCCCHHHHCCHHHHHHHHHHHH
GCQRIATFTEKKMKMIRIK
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]