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The map label for this gene is 220931808

Identifier: 220931808

GI number: 220931808

Start: 1043941

End: 1044888

Strand: Direct

Name: 220931808

Synonym: Hore_09650

Alternate gene names: NA

Gene position: 1043941-1044888 (Clockwise)

Preceding gene: 220931807

Following gene: 220931809

Centisome position: 40.49

GC content: 34.49

Gene sequence:

>948_bases
TTGAAAATCATTGATTTACATTGTGATACCATCAGTAAACTGTATAAATTTTCTGGCAGACAGGGATTAAGGAGTAATGA
ATTACATGTTGACCTTGAAAAATTGAGACAGGCAGGTAGTAAAGCCCAGTTTTTTGCCCTGTTTCTGGACAAAAATAATT
TGCCAGCAGGTACGGATTCTTATCAAATCTTTTTAGAAATGCTCGATGTTTTTAAAAAAGAGCTTGCCAAAAACAGTGAC
ATGGTTTCCCTGGCCAGAAATTATAGTGAATTACAAAAAAATGAAAGCGAGGGTAAAATATCTGCCTTTTTAACGATTGA
GGAAGGGGCTGTTCTTCAGGGTAAATTGAGTAATTTAAAAAAAATATACCGACTCGGGGTCAGGCTTATTACTTTAACCT
GGAATTACCCCAATGAGATTGGTTTTCCAAACATGAAAAATTATAAAGATAAGGGTTTAACACCTTTTGGTAATGAAGTT
ATCCGGGAAATGAATCACCTGGGAATGATAATAGATGTATCTCACCTGTCTGATAAAGGGTTTTATGATGTTATAAATTT
ATCCAGAAAGCCCGTTATTGCCTCTCATTCCAATGCACGTTCTTTACATAACCATCCCCGGAATTTAACCGATGATATGA
TTAAACTTATTGGTGAACAAGGGGGAGTTATCGGGATTAATTTTAATTCATATTTTTTAGGGGATACAAAAATAAGCACC
ATTGCAGATATTATTAAACATATTAAGCATGTTAAAAAGGTCGGTGGTAGTGATGTTATTGCCCTCGGTTCAGATTATGA
TGGGATTTCCTGCCAGCTGGAACTCAAAAATATTGGGCAAATACCGAATCTTATTTATACCCTGGAAAAGTATGGATTCT
CTGATGATGATATAGATAAATTTACCTATAAAAATGTGGAAAGAGTTATCAAGGATGTCTTAAATTAA

Upstream 100 bases:

>100_bases
ACAATTATCTATACTGGGTAAAGAAATAAGATAAATTTAAAGTAATAGAATAATAATAAGGATATAATTTTATTTAAAAA
CCTGGGGGGGTCAATTTAAC

Downstream 100 bases:

>100_bases
TTTGGTTTATCTGTACTGGGTTATTTATATTAATTATTTTTACAGTAAAAGGTTTTTGGGTCTTTTCAAAGAATTAATTA
TATAAATTTGTCTTTTATAG

Product: Membrane dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKIIDLHCDTISKLYKFSGRQGLRSNELHVDLEKLRQAGSKAQFFALFLDKNNLPAGTDSYQIFLEMLDVFKKELAKNSD
MVSLARNYSELQKNESEGKISAFLTIEEGAVLQGKLSNLKKIYRLGVRLITLTWNYPNEIGFPNMKNYKDKGLTPFGNEV
IREMNHLGMIIDVSHLSDKGFYDVINLSRKPVIASHSNARSLHNHPRNLTDDMIKLIGEQGGVIGINFNSYFLGDTKIST
IADIIKHIKHVKKVGGSDVIALGSDYDGISCQLELKNIGQIPNLIYTLEKYGFSDDDIDKFTYKNVERVIKDVLN

Sequences:

>Translated_315_residues
MKIIDLHCDTISKLYKFSGRQGLRSNELHVDLEKLRQAGSKAQFFALFLDKNNLPAGTDSYQIFLEMLDVFKKELAKNSD
MVSLARNYSELQKNESEGKISAFLTIEEGAVLQGKLSNLKKIYRLGVRLITLTWNYPNEIGFPNMKNYKDKGLTPFGNEV
IREMNHLGMIIDVSHLSDKGFYDVINLSRKPVIASHSNARSLHNHPRNLTDDMIKLIGEQGGVIGINFNSYFLGDTKIST
IADIIKHIKHVKKVGGSDVIALGSDYDGISCQLELKNIGQIPNLIYTLEKYGFSDDDIDKFTYKNVERVIKDVLN
>Mature_315_residues
MKIIDLHCDTISKLYKFSGRQGLRSNELHVDLEKLRQAGSKAQFFALFLDKNNLPAGTDSYQIFLEMLDVFKKELAKNSD
MVSLARNYSELQKNESEGKISAFLTIEEGAVLQGKLSNLKKIYRLGVRLITLTWNYPNEIGFPNMKNYKDKGLTPFGNEV
IREMNHLGMIIDVSHLSDKGFYDVINLSRKPVIASHSNARSLHNHPRNLTDDMIKLIGEQGGVIGINFNSYFLGDTKIST
IADIIKHIKHVKKVGGSDVIALGSDYDGISCQLELKNIGQIPNLIYTLEKYGFSDDDIDKFTYKNVERVIKDVLN

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=297, Percent_Identity=27.2727272727273, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI4758190, Length=297, Percent_Identity=27.2727272727273, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI11641269, Length=297, Percent_Identity=31.3131313131313, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI193211608, Length=297, Percent_Identity=28.956228956229, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI193211610, Length=297, Percent_Identity=28.956228956229, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI221475880, Length=297, Percent_Identity=34.006734006734, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI161083233, Length=293, Percent_Identity=31.740614334471, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI281362638, Length=293, Percent_Identity=31.3993174061433, Blast_Score=164, Evalue=9e-41,
Organism=Drosophila melanogaster, GI281362636, Length=293, Percent_Identity=31.3993174061433, Blast_Score=164, Evalue=9e-41,
Organism=Drosophila melanogaster, GI21356391, Length=227, Percent_Identity=26.8722466960352, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 35594; Mature: 35594

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIDLHCDTISKLYKFSGRQGLRSNELHVDLEKLRQAGSKAQFFALFLDKNNLPAGTDS
CEEEEECHHHHHHHHHHCCCCCCCCCCCEEEHHHHHCCCCCCEEEEEEEECCCCCCCCHH
YQIFLEMLDVFKKELAKNSDMVSLARNYSELQKNESEGKISAFLTIEEGAVLQGKLSNLK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEHHHHHHHH
KIYRLGVRLITLTWNYPNEIGFPNMKNYKDKGLTPFGNEVIREMNHLGMIIDVSHLSDKG
HHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCC
FYDVINLSRKPVIASHSNARSLHNHPRNLTDDMIKLIGEQGGVIGINFNSYFLGDTKIST
CHHHHCCCCCCEEECCCCCHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCEEECCCHHHH
IADIIKHIKHVKKVGGSDVIALGSDYDGISCQLELKNIGQIPNLIYTLEKYGFSDDDIDK
HHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCHHH
FTYKNVERVIKDVLN
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIIDLHCDTISKLYKFSGRQGLRSNELHVDLEKLRQAGSKAQFFALFLDKNNLPAGTDS
CEEEEECHHHHHHHHHHCCCCCCCCCCCEEEHHHHHCCCCCCEEEEEEEECCCCCCCCHH
YQIFLEMLDVFKKELAKNSDMVSLARNYSELQKNESEGKISAFLTIEEGAVLQGKLSNLK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEHHHHHHHH
KIYRLGVRLITLTWNYPNEIGFPNMKNYKDKGLTPFGNEVIREMNHLGMIIDVSHLSDKG
HHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCC
FYDVINLSRKPVIASHSNARSLHNHPRNLTDDMIKLIGEQGGVIGINFNSYFLGDTKIST
CHHHHCCCCCCEEECCCCCHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCEEECCCHHHH
IADIIKHIKHVKKVGGSDVIALGSDYDGISCQLELKNIGQIPNLIYTLEKYGFSDDDIDK
HHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCHHH
FTYKNVERVIKDVLN
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]