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The map label for this gene is natA [H]

Identifier: 220931700

GI number: 220931700

Start: 921399

End: 922187

Strand: Direct

Name: natA [H]

Synonym: Hore_08570

Alternate gene names: 220931700

Gene position: 921399-922187 (Clockwise)

Preceding gene: 220931699

Following gene: 220931702

Centisome position: 35.74

GC content: 35.23

Gene sequence:

>789_bases
TTGGTTGGCAATGTTTTTATATATTATATTTCTTCCGGTGAGATAAAGGTCAACGGCCTGGTGCCATATGAAAATAGAAA
AGAAAACTCAATGCATATGGGAGTGGTTTTTGGCCAGAGATCACAATTATACTGGGATATTCCTGTTGAGGAAACTTTTG
AACTTTTTAAGAAGATGTACAGGATTGATGAGAAACGTTTTAAGGAAAATGTTGAATTCTATGTAGACTTATTGGAAATG
GGTGATTTTATAAGGAAACCTGTCCGGACATTAAGCCTTGGCCAGAAGATGAGGGCGAACTTGACAGTGGCCTTGCTCCA
TGACCCTGATGTTCTTTATCTGGATGAACCTACCATTGGCCTCGATGTTGTGGTGAAGAGTAAAATAAGAAAGTTTATTA
AAGCGATAAATAAGGAAAAGGGAACCACTGTTATCCTTACGACCCATGATATGAATGATATTGAAAATATATGTGACCGG
ATTATCTTGATAGACCAGGGGCAGATCTTATATGACGGCAGGCTTGCTGATTTCAAGGAAAACTATGGGAAACAGTATAC
AATGATGGTTCAGTTTTCTGATAATAATATAGAAATAAAAGATTCCAGGTTTAATATACTAAAAGAAGATGGGCAGTTCA
AATGGTTATCTTTTTTGAAAGAGGATATAACCGTTGCTGAAGCAGTTAATTATTTAAGCAGAAATTATAATATAATCGAT
CTGAGTATCAAAGAACCTGATATTGAGGATATTGTCAGAAGGATATATGAGAATAAAATAGCCTTATAA

Upstream 100 bases:

>100_bases
AGTTAATTTACACAGTACTTTATACGATATCTTTCGTATCACATTTTATACATAAATTAACCAGAATTGATTTGTTTTCT
GTTATTAGTTTATTCGGTTT

Downstream 100 bases:

>100_bases
TACTAAAAAAATAGGGATACTTACAAAAACAAGGGATAGTGTAAAATTTAAGTAGGAAGCAGGAAAAGGAGGTATAAATA
TAGAAATAGAGACCCAAACA

Product: ABC transporter-like protein

Products: NA

Alternate protein names: Na(+) ABC transporter [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MVGNVFIYYISSGEIKVNGLVPYENRKENSMHMGVVFGQRSQLYWDIPVEETFELFKKMYRIDEKRFKENVEFYVDLLEM
GDFIRKPVRTLSLGQKMRANLTVALLHDPDVLYLDEPTIGLDVVVKSKIRKFIKAINKEKGTTVILTTHDMNDIENICDR
IILIDQGQILYDGRLADFKENYGKQYTMMVQFSDNNIEIKDSRFNILKEDGQFKWLSFLKEDITVAEAVNYLSRNYNIID
LSIKEPDIEDIVRRIYENKIAL

Sequences:

>Translated_262_residues
MVGNVFIYYISSGEIKVNGLVPYENRKENSMHMGVVFGQRSQLYWDIPVEETFELFKKMYRIDEKRFKENVEFYVDLLEM
GDFIRKPVRTLSLGQKMRANLTVALLHDPDVLYLDEPTIGLDVVVKSKIRKFIKAINKEKGTTVILTTHDMNDIENICDR
IILIDQGQILYDGRLADFKENYGKQYTMMVQFSDNNIEIKDSRFNILKEDGQFKWLSFLKEDITVAEAVNYLSRNYNIID
LSIKEPDIEDIVRRIYENKIAL
>Mature_262_residues
MVGNVFIYYISSGEIKVNGLVPYENRKENSMHMGVVFGQRSQLYWDIPVEETFELFKKMYRIDEKRFKENVEFYVDLLEM
GDFIRKPVRTLSLGQKMRANLTVALLHDPDVLYLDEPTIGLDVVVKSKIRKFIKAINKEKGTTVILTTHDMNDIENICDR
IILIDQGQILYDGRLADFKENYGKQYTMMVQFSDNNIEIKDSRFNILKEDGQFKWLSFLKEDITVAEAVNYLSRNYNIID
LSIKEPDIEDIVRRIYENKIAL

Specific function: Involved in ATP-dependent electrogenic sodium extrusion [H]

COG id: COG4586

COG function: function code R; ABC-type uncharacterized transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27262624, Length=191, Percent_Identity=25.130890052356, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI27262626, Length=191, Percent_Identity=25.130890052356, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI153792144, Length=193, Percent_Identity=25.9067357512953, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI6005701, Length=152, Percent_Identity=28.9473684210526, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI27881501, Length=154, Percent_Identity=29.2207792207792, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI30795238, Length=154, Percent_Identity=29.2207792207792, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI27477115, Length=152, Percent_Identity=28.9473684210526, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI21536376, Length=207, Percent_Identity=27.536231884058, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI27436953, Length=254, Percent_Identity=21.6535433070866, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI45446740, Length=253, Percent_Identity=24.901185770751, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI47078218, Length=253, Percent_Identity=24.901185770751, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI116734710, Length=138, Percent_Identity=29.7101449275362, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI150417984, Length=167, Percent_Identity=23.9520958083832, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI87081782, Length=171, Percent_Identity=32.7485380116959, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI48994943, Length=145, Percent_Identity=30.3448275862069, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786319, Length=111, Percent_Identity=36.036036036036, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790467, Length=172, Percent_Identity=27.3255813953488, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787164, Length=83, Percent_Identity=40.9638554216867, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI145693107, Length=177, Percent_Identity=29.3785310734463, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1786703, Length=165, Percent_Identity=30.9090909090909, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788761, Length=115, Percent_Identity=27.8260869565217, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786398, Length=103, Percent_Identity=34.9514563106796, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788450, Length=132, Percent_Identity=26.5151515151515, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786345, Length=111, Percent_Identity=28.8288288288288, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787370, Length=153, Percent_Identity=27.4509803921569, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1790544, Length=99, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787112, Length=98, Percent_Identity=36.734693877551, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789891, Length=80, Percent_Identity=36.25, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082267, Length=129, Percent_Identity=26.3565891472868, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI48994883, Length=131, Percent_Identity=30.5343511450382, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081791, Length=181, Percent_Identity=24.8618784530387, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=187, Percent_Identity=29.4117647058824, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71983516, Length=232, Percent_Identity=25.4310344827586, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71983523, Length=232, Percent_Identity=25.4310344827586, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71983510, Length=232, Percent_Identity=25.4310344827586, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17510237, Length=181, Percent_Identity=28.1767955801105, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI115533608, Length=193, Percent_Identity=26.4248704663212, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI193202878, Length=127, Percent_Identity=28.3464566929134, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24650855, Length=164, Percent_Identity=31.0975609756098, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24650853, Length=141, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362751, Length=164, Percent_Identity=31.7073170731707, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI85725262, Length=205, Percent_Identity=29.7560975609756, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24582014, Length=176, Percent_Identity=27.8409090909091, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582012, Length=176, Percent_Identity=27.8409090909091, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24643674, Length=197, Percent_Identity=24.8730964467005, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24666092, Length=170, Percent_Identity=27.0588235294118, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24648314, Length=189, Percent_Identity=26.984126984127, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 30765; Mature: 30765

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGNVFIYYISSGEIKVNGLVPYENRKENSMHMGVVFGQRSQLYWDIPVEETFELFKKMY
CCCCEEEEEEECCEEEEEEECCCCCCCCCCEEEEEEEECCCCEEEECCHHHHHHHHHHHH
RIDEKRFKENVEFYVDLLEMGDFIRKPVRTLSLGQKMRANLTVALLHDPDVLYLDEPTIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEEEECCCEEEECCCCCC
LDVVVKSKIRKFIKAINKEKGTTVILTTHDMNDIENICDRIILIDQGQILYDGRLADFKE
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCEEEEEECCCEEECCCCHHHHH
NYGKQYTMMVQFSDNNIEIKDSRFNILKEDGQFKWLSFLKEDITVAEAVNYLSRNYNIID
CCCCEEEEEEEECCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEE
LSIKEPDIEDIVRRIYENKIAL
EEECCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVGNVFIYYISSGEIKVNGLVPYENRKENSMHMGVVFGQRSQLYWDIPVEETFELFKKMY
CCCCEEEEEEECCEEEEEEECCCCCCCCCCEEEEEEEECCCCEEEECCHHHHHHHHHHHH
RIDEKRFKENVEFYVDLLEMGDFIRKPVRTLSLGQKMRANLTVALLHDPDVLYLDEPTIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEEEECCCEEEECCCCCC
LDVVVKSKIRKFIKAINKEKGTTVILTTHDMNDIENICDRIILIDQGQILYDGRLADFKE
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCEEEEEECCCEEECCCCHHHHH
NYGKQYTMMVQFSDNNIEIKDSRFNILKEDGQFKWLSFLKEDITVAEAVNYLSRNYNIID
CCCCEEEEEEEECCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEE
LSIKEPDIEDIVRRIYENKIAL
EEECCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9106203; 9274031; 9384377 [H]