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The map label for this gene is ribH [H]

Identifier: 220931699

GI number: 220931699

Start: 920501

End: 920971

Strand: Direct

Name: ribH [H]

Synonym: Hore_08560

Alternate gene names: 220931699

Gene position: 920501-920971 (Clockwise)

Preceding gene: 220931698

Following gene: 220931700

Centisome position: 35.7

GC content: 43.1

Gene sequence:

>471_bases
ATGAGAAATGTTATTGAAGGCCAATTGATTGGTAATGGTATAAGGGCAGGGATAATAGTCAGCCGCTTTAATGATTTTAT
AACTGAAAAACTATTGGAGGGTGCTCTTGATGGTTTGAGAAGGCATGGTGTTAAAGAGGAAGATATAAGCATTATAAGGG
TTCCCGGTTCCTTTGAAATACCCCTTATTGCTTCAAAAGCAGCCAGGTCAGGCAGATATGATGGCATAATCTGCCTGGGT
GTAGTAATAAGGGGTGAAACACCCCATTTTGAATATGTCTCTGCAGAGGTATCTAAAGGCATAGCCAAGGTTGCCCTTGA
TACGGGGGTGCCTGTAATATTTGCTGTCCTGACTACTGATAACATAGAACAGGCCATCGCCCGGGCTGGTACCAAACATG
GCAATAAGGGTTTTGATGCTGCCCTGTCCCTGATAGAGATGGTTAACTTGATGAAGGCAATGTCTGTTTAA

Upstream 100 bases:

>100_bases
TCTGTTCATTAACCTTATTACCTTAATGTTCTTATATAATTATCTTACTTTCTTAAATTTGTTAATATCCTGATTTTTTA
TAGAAAGGAGTTAATTATTT

Downstream 100 bases:

>100_bases
GAGTGTTTACATAACAAGACATTTAATGCAGATACTTAGCAATAAATGCCATTAATTGCTTGAAAGGCATGTTGTATTCT
GGTATAATTAACTAAAAAAT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MRNVIEGQLIGNGIRAGIIVSRFNDFITEKLLEGALDGLRRHGVKEEDISIIRVPGSFEIPLIASKAARSGRYDGIICLG
VVIRGETPHFEYVSAEVSKGIAKVALDTGVPVIFAVLTTDNIEQAIARAGTKHGNKGFDAALSLIEMVNLMKAMSV

Sequences:

>Translated_156_residues
MRNVIEGQLIGNGIRAGIIVSRFNDFITEKLLEGALDGLRRHGVKEEDISIIRVPGSFEIPLIASKAARSGRYDGIICLG
VVIRGETPHFEYVSAEVSKGIAKVALDTGVPVIFAVLTTDNIEQAIARAGTKHGNKGFDAALSLIEMVNLMKAMSV
>Mature_156_residues
MRNVIEGQLIGNGIRAGIIVSRFNDFITEKLLEGALDGLRRHGVKEEDISIIRVPGSFEIPLIASKAARSGRYDGIICLG
VVIRGETPHFEYVSAEVSKGIAKVALDTGVPVIFAVLTTDNIEQAIARAGTKHGNKGFDAALSLIEMVNLMKAMSV

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=153, Percent_Identity=53.5947712418301, Blast_Score=173, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6324429, Length=146, Percent_Identity=37.6712328767123, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16732; Mature: 16732

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNVIEGQLIGNGIRAGIIVSRFNDFITEKLLEGALDGLRRHGVKEEDISIIRVPGSFEI
CCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCC
PLIASKAARSGRYDGIICLGVVIRGETPHFEYVSAEVSKGIAKVALDTGVPVIFAVLTTD
CEEEHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
NIEQAIARAGTKHGNKGFDAALSLIEMVNLMKAMSV
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRNVIEGQLIGNGIRAGIIVSRFNDFITEKLLEGALDGLRRHGVKEEDISIIRVPGSFEI
CCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCC
PLIASKAARSGRYDGIICLGVVIRGETPHFEYVSAEVSKGIAKVALDTGVPVIFAVLTTD
CEEEHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
NIEQAIARAGTKHGNKGFDAALSLIEMVNLMKAMSV
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA