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The map label for this gene is efp

Identifier: 220931459

GI number: 220931459

Start: 669283

End: 669843

Strand: Direct

Name: efp

Synonym: Hore_06150

Alternate gene names: 220931459

Gene position: 669283-669843 (Clockwise)

Preceding gene: 220931458

Following gene: 220931460

Centisome position: 25.96

GC content: 37.61

Gene sequence:

>561_bases
ATGATATCAACCAATGATTTTCACAATGGTCTAACTATTGAGCTTGATGGGACTGTTTATCAGGTGGTTAAATTTCAACA
TTCTAAAACCGGACGGGGAGGGGCTTTTGTACGAACAAAACTTAGAAATATCGAAGATGGGGGTATTATTGAAAAGACCT
TTAGAGCCGGTGAAAAAGTAAAGAAAGCCCATGTTGATCAGAAAAATATGCAGTATCTTTATCATAATGGTGATGATTAC
GTATTTATGGATACAGATACTTATGAACAGCTTTCCATTAGCAATGAACAGCTGGGAGATAAAGTCGATTACCTTAAAGA
AAACATGAGCCTTGAAGTTCTAATGTATGAAAATAGACCTATTGATATAAATTTACCAACCTTTGTAGAACTTGAAGTTG
AAAAAACCCAACCTGGTATCAGGGGTGATACTGTATCAGGTGGTTCCAAACCTGCTACTCTGGAAACCGGGGCAGTTGTT
CAGGTCCCCCTATTTATTAATGAAGGAGATGTAATTAAAGTGGATACCAGGAGCGGTGAGTATATAGAACGGGTATCATG
A

Upstream 100 bases:

>100_bases
ATAAATACAGAAATGAAAACATTACCCTGAATCATTAAAAGTCATGTTTCAGGGAGAAAATAATATAATTATAGCTATTA
TTTTTAAGGAGGAATAAAGA

Downstream 100 bases:

>100_bases
TCAGAAAGGCTTTTTTTATCAAAAGGTTAAACAGGTTTGCTGCCCTTGTTTCCCTGATGGGGGAAGAGGAGAAAGTGTTT
GTCCCCAATTCCGGCAGAAT

Product: translation elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MISTNDFHNGLTIELDGTVYQVVKFQHSKTGRGGAFVRTKLRNIEDGGIIEKTFRAGEKVKKAHVDQKNMQYLYHNGDDY
VFMDTDTYEQLSISNEQLGDKVDYLKENMSLEVLMYENRPIDINLPTFVELEVEKTQPGIRGDTVSGGSKPATLETGAVV
QVPLFINEGDVIKVDTRSGEYIERVS

Sequences:

>Translated_186_residues
MISTNDFHNGLTIELDGTVYQVVKFQHSKTGRGGAFVRTKLRNIEDGGIIEKTFRAGEKVKKAHVDQKNMQYLYHNGDDY
VFMDTDTYEQLSISNEQLGDKVDYLKENMSLEVLMYENRPIDINLPTFVELEVEKTQPGIRGDTVSGGSKPATLETGAVV
QVPLFINEGDVIKVDTRSGEYIERVS
>Mature_186_residues
MISTNDFHNGLTIELDGTVYQVVKFQHSKTGRGGAFVRTKLRNIEDGGIIEKTFRAGEKVKKAHVDQKNMQYLYHNGDDY
VFMDTDTYEQLSISNEQLGDKVDYLKENMSLEVLMYENRPIDINLPTFVELEVEKTQPGIRGDTVSGGSKPATLETGAVV
QVPLFINEGDVIKVDTRSGEYIERVS

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=47.2527472527472, Blast_Score=177, Evalue=5e-46,
Organism=Escherichia coli, GI87082061, Length=189, Percent_Identity=27.5132275132275, Blast_Score=97, Evalue=8e-22,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_HALOH (B8D2E5)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002508367.1
- ProteinModelPortal:   B8D2E5
- SMR:   B8D2E5
- GeneID:   7314520
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_06150
- HOGENOM:   HBG303311
- OMA:   WKVLEFL
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20941; Mature: 20941

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTNDFHNGLTIELDGTVYQVVKFQHSKTGRGGAFVRTKLRNIEDGGIIEKTFRAGEKV
CCCCCCCCCCEEEEECCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCEEHHHHHCCHHH
KKAHVDQKNMQYLYHNGDDYVFMDTDTYEQLSISNEQLGDKVDYLKENMSLEVLMYENRP
HHHHCCCCCCEEEEECCCCEEEEECCCCHHEECCCHHHCCHHHHHHCCCCEEEEEECCCC
IDINLPTFVELEVEKTQPGIRGDTVSGGSKPATLETGAVVQVPLFINEGDVIKVDTRSGE
EEEECCCEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCEEEEECCCCC
YIERVS
EEECCC
>Mature Secondary Structure
MISTNDFHNGLTIELDGTVYQVVKFQHSKTGRGGAFVRTKLRNIEDGGIIEKTFRAGEKV
CCCCCCCCCCEEEEECCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCEEHHHHHCCHHH
KKAHVDQKNMQYLYHNGDDYVFMDTDTYEQLSISNEQLGDKVDYLKENMSLEVLMYENRP
HHHHCCCCCCEEEEECCCCEEEEECCCCHHEECCCHHHCCHHHHHHCCCCEEEEEECCCC
IDINLPTFVELEVEKTQPGIRGDTVSGGSKPATLETGAVVQVPLFINEGDVIKVDTRSGE
EEEECCCEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCEEEEECCCCC
YIERVS
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA