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The map label for this gene is yqhT [H]

Identifier: 220931458

GI number: 220931458

Start: 668058

End: 669128

Strand: Direct

Name: yqhT [H]

Synonym: Hore_06140

Alternate gene names: 220931458

Gene position: 668058-669128 (Clockwise)

Preceding gene: 220931457

Following gene: 220931459

Centisome position: 25.91

GC content: 39.31

Gene sequence:

>1071_bases
ATGGAAAAGAGAATACAGCAATTAAGAAAAGCTATGAAAAAAATGGATCTGGACAGTTTGATTATTGATTCCAGCCATAA
CCGATTTTATTTAACCGGTTTTACTGGCACAGCCGGGAGGGTATTATTCACACCAGAAAATAATTATTTTATAACAGATT
TTCGTTATACAGAACAGGCCCATGAGCAGATATCGGGTTTTGAAATACTGGAGGTTAACCAGAAAGCAGTTGTGGAAATT
TCTGATATTCTTGATCAGGATAATTCTAGCCGGGTCGGTTTTGAAGCAAGAAGTGTTACCTATGATGTTTTTCAAAAATA
CAAAAAGACATTTAATGAAAGTATCAAGCTTGTACCAACGGCCGGGCTTGTTGAGAAAATCAGGGTTGTTAAAGATAGAA
GTGAAGTTGAGACTATTAAAAAGGCAGCTGAGATAGCCGATAGTGCTTTTAAACACATCCTTGATTTTATAAAACCGGGG
GTAACAGAAAGGGAGGTTGCCCTGGAATTAGAATACTTTATGAAAAAAAACGGTGGAGAAGGAAATGCCTTTGATTTCAT
AGTTGCTTCTGGTAAAAGGTCTTCTTTGCCCCATGGGGTAGCCAGTGATAAGGTTATTGAAGATGGGGATTTTGTTACCA
TGGATTTTGGAACCTATTATAAGGGTTATTGTTCTGATATGACACGGACAGTGATAGTGGGAGAACCGACCCCTGAACAA
AAGGAGATTTATAATATTGTGCTAAAAGCTCAGAATGAGGTCATAAAAAATATCAGAGCAGGTATGACCTGTAAAGAGGC
AGATGCTATTGCCCGTGATATAATAGCTGAACATGGGTATAAGGATAATTTTGGTCACAGCCTCGGTCATGGCCTCGGAG
TTGAAGTTCATGAGGATCCCCGTGTTTCTTATGCTTCAGATGAGGTATTAAAACCGGGGATGGTAGTTACTGATGAACCC
GGTATTTATATTGCTGACTGGGGTGGAGTCAGGATAGAAGATGACCTGTTGATAACTGAAGATGGATGTGAAGTTCTGAC
CAGTTCCCCTAAAGATCTTATTTCGGTGTAG

Upstream 100 bases:

>100_bases
GCTTCAGTTGCGGTCGGTCAGATTACCGGACTGGGGACAGAGGGTTATTTATATGCCCTGGAAGCCATTGTTAATATTAT
TAAAAAGGGGAGTTATTAAA

Downstream 100 bases:

>100_bases
GTATAGGTGCAGGCATAAAGGTATCAATATGATGGTAAAAATAATTTCATTATAATAAATACAGAAATGAAAACATTACC
CTGAATCATTAAAAGTCATG

Product: peptidase M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MEKRIQQLRKAMKKMDLDSLIIDSSHNRFYLTGFTGTAGRVLFTPENNYFITDFRYTEQAHEQISGFEILEVNQKAVVEI
SDILDQDNSSRVGFEARSVTYDVFQKYKKTFNESIKLVPTAGLVEKIRVVKDRSEVETIKKAAEIADSAFKHILDFIKPG
VTEREVALELEYFMKKNGGEGNAFDFIVASGKRSSLPHGVASDKVIEDGDFVTMDFGTYYKGYCSDMTRTVIVGEPTPEQ
KEIYNIVLKAQNEVIKNIRAGMTCKEADAIARDIIAEHGYKDNFGHSLGHGLGVEVHEDPRVSYASDEVLKPGMVVTDEP
GIYIADWGGVRIEDDLLITEDGCEVLTSSPKDLISV

Sequences:

>Translated_356_residues
MEKRIQQLRKAMKKMDLDSLIIDSSHNRFYLTGFTGTAGRVLFTPENNYFITDFRYTEQAHEQISGFEILEVNQKAVVEI
SDILDQDNSSRVGFEARSVTYDVFQKYKKTFNESIKLVPTAGLVEKIRVVKDRSEVETIKKAAEIADSAFKHILDFIKPG
VTEREVALELEYFMKKNGGEGNAFDFIVASGKRSSLPHGVASDKVIEDGDFVTMDFGTYYKGYCSDMTRTVIVGEPTPEQ
KEIYNIVLKAQNEVIKNIRAGMTCKEADAIARDIIAEHGYKDNFGHSLGHGLGVEVHEDPRVSYASDEVLKPGMVVTDEP
GIYIADWGGVRIEDDLLITEDGCEVLTSSPKDLISV
>Mature_356_residues
MEKRIQQLRKAMKKMDLDSLIIDSSHNRFYLTGFTGTAGRVLFTPENNYFITDFRYTEQAHEQISGFEILEVNQKAVVEI
SDILDQDNSSRVGFEARSVTYDVFQKYKKTFNESIKLVPTAGLVEKIRVVKDRSEVETIKKAAEIADSAFKHILDFIKPG
VTEREVALELEYFMKKNGGEGNAFDFIVASGKRSSLPHGVASDKVIEDGDFVTMDFGTYYKGYCSDMTRTVIVGEPTPEQ
KEIYNIVLKAQNEVIKNIRAGMTCKEADAIARDIIAEHGYKDNFGHSLGHGLGVEVHEDPRVSYASDEVLKPGMVVTDEP
GIYIADWGGVRIEDDLLITEDGCEVLTSSPKDLISV

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=260, Percent_Identity=30, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI260593665, Length=322, Percent_Identity=27.3291925465839, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI149589008, Length=322, Percent_Identity=27.3291925465839, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI260593663, Length=243, Percent_Identity=27.9835390946502, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI264681563, Length=227, Percent_Identity=31.2775330396476, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI93141226, Length=167, Percent_Identity=32.9341317365269, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI264681565, Length=149, Percent_Identity=35.5704697986577, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI40385867, Length=287, Percent_Identity=25.4355400696864, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI164420681, Length=242, Percent_Identity=24.7933884297521, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788728, Length=357, Percent_Identity=40.6162464985994, Blast_Score=284, Evalue=7e-78,
Organism=Escherichia coli, GI1789275, Length=270, Percent_Identity=30.3703703703704, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786364, Length=253, Percent_Identity=24.5059288537549, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508215, Length=292, Percent_Identity=27.0547945205479, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71989583, Length=289, Percent_Identity=24.5674740484429, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71996291, Length=250, Percent_Identity=24.4, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321118, Length=288, Percent_Identity=28.125, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320922, Length=260, Percent_Identity=30, Blast_Score=102, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6323273, Length=255, Percent_Identity=27.843137254902, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322999, Length=175, Percent_Identity=30.8571428571429, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920384, Length=272, Percent_Identity=31.9852941176471, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21357079, Length=293, Percent_Identity=30.0341296928328, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI21355531, Length=252, Percent_Identity=24.6031746031746, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI161078230, Length=216, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21357287, Length=216, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39865; Mature: 39865

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRIQQLRKAMKKMDLDSLIIDSSHNRFYLTGFTGTAGRVLFTPENNYFITDFRYTEQA
CCHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCEEEECCCCCEEEEEEEHHHHH
HEQISGFEILEVNQKAVVEISDILDQDNSSRVGFEARSVTYDVFQKYKKTFNESIKLVPT
HHHHCCEEEEEECCHHHEEHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEC
AGLVEKIRVVKDRSEVETIKKAAEIADSAFKHILDFIKPGVTEREVALELEYFMKKNGGE
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
GNAFDFIVASGKRSSLPHGVASDKVIEDGDFVTMDFGTYYKGYCSDMTRTVIVGEPTPEQ
CCEEEEEEECCCCCCCCCCCCCCCEEECCCEEEEECCCHHHHHHCCCEEEEEEECCCCCH
KEIYNIVLKAQNEVIKNIRAGMTCKEADAIARDIIAEHGYKDNFGHSLGHGLGVEVHEDP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCEECCCC
RVSYASDEVLKPGMVVTDEPGIYIADWGGVRIEDDLLITEDGCEVLTSSPKDLISV
CCCCCCHHHCCCCEEEECCCCEEEECCCCEEEECCEEEECCCCHHHHCCCHHHHCC
>Mature Secondary Structure
MEKRIQQLRKAMKKMDLDSLIIDSSHNRFYLTGFTGTAGRVLFTPENNYFITDFRYTEQA
CCHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCEEEECCCCCEEEEEEEHHHHH
HEQISGFEILEVNQKAVVEISDILDQDNSSRVGFEARSVTYDVFQKYKKTFNESIKLVPT
HHHHCCEEEEEECCHHHEEHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEC
AGLVEKIRVVKDRSEVETIKKAAEIADSAFKHILDFIKPGVTEREVALELEYFMKKNGGE
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
GNAFDFIVASGKRSSLPHGVASDKVIEDGDFVTMDFGTYYKGYCSDMTRTVIVGEPTPEQ
CCEEEEEEECCCCCCCCCCCCCCCEEECCCEEEEECCCHHHHHHCCCEEEEEEECCCCCH
KEIYNIVLKAQNEVIKNIRAGMTCKEADAIARDIIAEHGYKDNFGHSLGHGLGVEVHEDP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCEECCCC
RVSYASDEVLKPGMVVTDEPGIYIADWGGVRIEDDLLITEDGCEVLTSSPKDLISV
CCCCCCHHHCCCCEEEECCCCEEEECCCCEEEECCEEEECCCCHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]