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The map label for this gene is fur [H]

Identifier: 220931434

GI number: 220931434

Start: 643194

End: 643631

Strand: Direct

Name: fur [H]

Synonym: Hore_05900

Alternate gene names: 220931434

Gene position: 643194-643631 (Clockwise)

Preceding gene: 220931432

Following gene: 220931435

Centisome position: 24.95

GC content: 29.68

Gene sequence:

>438_bases
ATGGAGAAACTTATAGAAAAGGTAACCAATATCTTAGGTTCAAATAATTATAAAATAACTTCCCAGAGAAAGGACATTTT
AAAGGTTTTGATTAAAAATAAAGAAAGGCATTTCAGTGCAGAAGAACTTTATGAAGAAGTAAAAAAAATAAACCCAGATG
TGGGTCTGGCCACTATTTACCGAAACCTGGAGATTTTCAGTGAACTTGGTATAACCCATCAACTTGATTTTGATGGAAAC
TTTAAGAAATATGAATTAAGCCTGGAAAGGCATCATCATCATTTAATATGTAAAAACTGTGGTAAAATTATAGAATTTAA
TGATGATGTACTTGAGGATTTTGAAAAAGATCTTGAAAAGCATTATAACTTTAAAATAGTGGACCATCAGATTAAATTTT
ATGGGATCTGTCAGGACTGTAAAAATGAAGATGAATAA

Upstream 100 bases:

>100_bases
ATAAACAGGTATATAAATATAACTAATCTGGTTAAGTATTTGTAATTTTATAGTAACACTGATAAAATATAATGGAATTA
ATAATCAGGAGGAATAAAAA

Downstream 100 bases:

>100_bases
TTGCGGGATTACAACAGTAAGTGGTAATTTTATAAGGTGTAATAACATAAAATCATTATATGAATACTAAAAACAGTATA
ACTACAAATGATAAAAAGGT

Product: Fur family ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MEKLIEKVTNILGSNNYKITSQRKDILKVLIKNKERHFSAEELYEEVKKINPDVGLATIYRNLEIFSELGITHQLDFDGN
FKKYELSLERHHHHLICKNCGKIIEFNDDVLEDFEKDLEKHYNFKIVDHQIKFYGICQDCKNEDE

Sequences:

>Translated_145_residues
MEKLIEKVTNILGSNNYKITSQRKDILKVLIKNKERHFSAEELYEEVKKINPDVGLATIYRNLEIFSELGITHQLDFDGN
FKKYELSLERHHHHLICKNCGKIIEFNDDVLEDFEKDLEKHYNFKIVDHQIKFYGICQDCKNEDE
>Mature_145_residues
MEKLIEKVTNILGSNNYKITSQRKDILKVLIKNKERHFSAEELYEEVKKINPDVGLATIYRNLEIFSELGITHQLDFDGN
FKKYELSLERHHHHLICKNCGKIIEFNDDVLEDFEKDLEKHYNFKIVDHQIKFYGICQDCKNEDE

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=130, Percent_Identity=39.2307692307692, Blast_Score=100, Evalue=3e-23,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17274; Mature: 17274

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLIEKVTNILGSNNYKITSQRKDILKVLIKNKERHFSAEELYEEVKKINPDVGLATIY
CHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHH
RNLEIFSELGITHQLDFDGNFKKYELSLERHHHHLICKNCGKIIEFNDDVLEDFEKDLEK
HHHHHHHHCCCEEEECCCCCCEEEEEEHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHH
HYNFKIVDHQIKFYGICQDCKNEDE
HCCEEEEECEEEEEEECHHCCCCCC
>Mature Secondary Structure
MEKLIEKVTNILGSNNYKITSQRKDILKVLIKNKERHFSAEELYEEVKKINPDVGLATIY
CHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHH
RNLEIFSELGITHQLDFDGNFKKYELSLERHHHHLICKNCGKIIEFNDDVLEDFEKDLEK
HHHHHHHHCCCEEEECCCCCCEEEEEEHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHH
HYNFKIVDHQIKFYGICQDCKNEDE
HCCEEEEECEEEEEEECHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083178 [H]