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The map label for this gene is polX [H]

Identifier: 220931411

GI number: 220931411

Start: 617042

End: 618763

Strand: Direct

Name: polX [H]

Synonym: Hore_05670

Alternate gene names: 220931411

Gene position: 617042-618763 (Clockwise)

Preceding gene: 220931410

Following gene: 220931412

Centisome position: 23.93

GC content: 37.8

Gene sequence:

>1722_bases
ATGTATCAATTAACCAATAAAGAAGTGTCCCGTATTTTGAAGGAACTGGCAAAACTTATGGAATTAAAGGGTGAGAATAA
ATTTAAAGTAAGGGCATACTATAATGCTTCCCGTCAGTTAATAAATATGTCTGATAATATTCAGGATCTGGCCCGTGAGG
GTAAGATAAGGAATATACCCGGGGTCGGGGAGGGGATAGCAAGAAGTATTAAAGAGATTATGGAAAAGGGGTATTCCCCT
GAACTTGAGGAGTTAAAGGCAGAATTACCCGGGGGGTTACTTGAAATTATTAAGATACCGGGTCTTGGCCCAAAAAGGGC
ATACCAGCTTTTTAATGAACTTGGGGTTACGAACCTTGAGGAACTAAAAAGTGCTTTGAATACTGGTAAAGCCAGGAAGT
TAAAAGGCTTTGGTGTGAAAACAGAAGAAAACCTTAAAAATAAAATTGAAAAATATGAGTCTTTTAAAAATACTTACCTT
CTCAAGGAAGCATTGGGGATACTGGATGAGCTGAAAAGGTATATTAAGAAATGCCCCGGAGTATCCCGGGTCAAAATGAC
AGGAGAGGCGAGAAGAAAAAAAGAACTGGTAAATTCTCTGGAAATACTTGTAGCCAGTAAGGAAAAGGAATCTGTTCTTG
AATACTTAAGGAAGTTATCGTTTGCAAAAAGTATAGAGGAAAAAGAAGAGAATGGATATTTACTTACCTTTGAGGATGAT
ATAAGAATTAAGGTTTTTATTGTGCCTCCAGATATGTTTTGTTTTTATCTATTCTATCTTACAGGTTCTAAAGACCATGT
CCAGAAAATGGAAACCATAGCTGATGATGCCGGGTATCAATTAACAATTAAGGGTTTATATAAGGATTCCAGCAAAATCA
AGGTTAAAAATGAAGAAGAAATTTATACTACCCTCGGGGTCAGTTATATTATCCCTGAACTCCGGGAAAACCGGGGTGAA
ATAACAGCCGGTTTTAAAAATTGCCTGCCTGATTCTATAAATTTAAGGGATATAAAGGGTGATCTCCATATTCATTCCAG
CTACAGTGATGGTGGTTTTAGTATCAGGGAGATTATTGAAGCTGCCCGGAAGAAGGGATATGAATACCTGGCTATTACAG
ACCATTCCCGTTCTTTAAAGGTTGCCAGTGGTTTGAGTGTTGACAGATTATTTAAGCAGATTGAAGAAATAGATAAACTT
CAGGAGGAATATGATGATATAATTATTTTTAAGGGAATAGAGGTAGATATAAATAAAGATGGTAGTCTTGATTATAGTGA
TGAGGTGTTATCTTACCTTGATTTTGTAATTGCATCGGTTCATACCGCTTTTAACATGGATAGAGATAAGATGACGTCAC
GGCTAATTAAGGCAATGGAAAACCCTCATGTTAATGCTATAGGGCATCCAAGGGGAAGGCTTCTAAAAAGACGTGACGCC
TATAAGATTGACATGGACAGGATAATTCAGGTTGCATCTGAAACCAATACCTGTCTTGAAATAAATTCTTCCCCGGATAG
GCTTGATATCGATGATGTTCTTGCACGGAAAGCTAAAGAGGTCGGAGTTAAGTTGGTGATTAATACCGATGCCCATCACC
TTGAAGAATTGAATAATATGTCCCTCGGGGTTGCTGTAGCCCGGAGAGGCTGGCTTGAAAGAGAAGATGTTATTAATACC
ATGAATGCAGAAGAGTTACAGGAATTATTAAGGAGGGATTAA

Upstream 100 bases:

>100_bases
CTCCACTGGTTAAACAGCGATTATCTCAGATTTTTGGGCCATGAATTTAGTTCATGGCCTTTATTTATGGTGTCTTATTT
TTTTCAGGGGGTAAGATAAA

Downstream 100 bases:

>100_bases
GGTGGAGGAAAGCTCCCTTGAAATACTGGAATTTGATAAAATAATAGACCGTGTTCAGGAATTTGCAGCAACCATCATTG
GAAAGGAAATTATATCCAGA

Product: DNA polymerase X family protein

Products: NA

Alternate protein names: DNA polymerase type-X; 3'-5' exodeoxyribonuclease; 3'-5' exonuclease [H]

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MYQLTNKEVSRILKELAKLMELKGENKFKVRAYYNASRQLINMSDNIQDLAREGKIRNIPGVGEGIARSIKEIMEKGYSP
ELEELKAELPGGLLEIIKIPGLGPKRAYQLFNELGVTNLEELKSALNTGKARKLKGFGVKTEENLKNKIEKYESFKNTYL
LKEALGILDELKRYIKKCPGVSRVKMTGEARRKKELVNSLEILVASKEKESVLEYLRKLSFAKSIEEKEENGYLLTFEDD
IRIKVFIVPPDMFCFYLFYLTGSKDHVQKMETIADDAGYQLTIKGLYKDSSKIKVKNEEEIYTTLGVSYIIPELRENRGE
ITAGFKNCLPDSINLRDIKGDLHIHSSYSDGGFSIREIIEAARKKGYEYLAITDHSRSLKVASGLSVDRLFKQIEEIDKL
QEEYDDIIIFKGIEVDINKDGSLDYSDEVLSYLDFVIASVHTAFNMDRDKMTSRLIKAMENPHVNAIGHPRGRLLKRRDA
YKIDMDRIIQVASETNTCLEINSSPDRLDIDDVLARKAKEVGVKLVINTDAHHLEELNNMSLGVAVARRGWLEREDVINT
MNAEELQELLRRD

Sequences:

>Translated_573_residues
MYQLTNKEVSRILKELAKLMELKGENKFKVRAYYNASRQLINMSDNIQDLAREGKIRNIPGVGEGIARSIKEIMEKGYSP
ELEELKAELPGGLLEIIKIPGLGPKRAYQLFNELGVTNLEELKSALNTGKARKLKGFGVKTEENLKNKIEKYESFKNTYL
LKEALGILDELKRYIKKCPGVSRVKMTGEARRKKELVNSLEILVASKEKESVLEYLRKLSFAKSIEEKEENGYLLTFEDD
IRIKVFIVPPDMFCFYLFYLTGSKDHVQKMETIADDAGYQLTIKGLYKDSSKIKVKNEEEIYTTLGVSYIIPELRENRGE
ITAGFKNCLPDSINLRDIKGDLHIHSSYSDGGFSIREIIEAARKKGYEYLAITDHSRSLKVASGLSVDRLFKQIEEIDKL
QEEYDDIIIFKGIEVDINKDGSLDYSDEVLSYLDFVIASVHTAFNMDRDKMTSRLIKAMENPHVNAIGHPRGRLLKRRDA
YKIDMDRIIQVASETNTCLEINSSPDRLDIDDVLARKAKEVGVKLVINTDAHHLEELNNMSLGVAVARRGWLEREDVINT
MNAEELQELLRRD
>Mature_573_residues
MYQLTNKEVSRILKELAKLMELKGENKFKVRAYYNASRQLINMSDNIQDLAREGKIRNIPGVGEGIARSIKEIMEKGYSP
ELEELKAELPGGLLEIIKIPGLGPKRAYQLFNELGVTNLEELKSALNTGKARKLKGFGVKTEENLKNKIEKYESFKNTYL
LKEALGILDELKRYIKKCPGVSRVKMTGEARRKKELVNSLEILVASKEKESVLEYLRKLSFAKSIEEKEENGYLLTFEDD
IRIKVFIVPPDMFCFYLFYLTGSKDHVQKMETIADDAGYQLTIKGLYKDSSKIKVKNEEEIYTTLGVSYIIPELRENRGE
ITAGFKNCLPDSINLRDIKGDLHIHSSYSDGGFSIREIIEAARKKGYEYLAITDHSRSLKVASGLSVDRLFKQIEEIDKL
QEEYDDIIIFKGIEVDINKDGSLDYSDEVLSYLDFVIASVHTAFNMDRDKMTSRLIKAMENPHVNAIGHPRGRLLKRRDA
YKIDMDRIIQVASETNTCLEINSSPDRLDIDDVLARKAKEVGVKLVINTDAHHLEELNNMSLGVAVARRGWLEREDVINT
MNAEELQELLRRD

Specific function: Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a sing

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the PHP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002054
- InterPro:   IPR010996
- InterPro:   IPR003583
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR022311 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 65453; Mature: 65453

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQLTNKEVSRILKELAKLMELKGENKFKVRAYYNASRQLINMSDNIQDLAREGKIRNIP
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHCCCCCCHHHHHHCCCCCCCC
GVGEGIARSIKEIMEKGYSPELEELKAELPGGLLEIIKIPGLGPKRAYQLFNELGVTNLE
CCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCHH
ELKSALNTGKARKLKGFGVKTEENLKNKIEKYESFKNTYLLKEALGILDELKRYIKKCPG
HHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VSRVKMTGEARRKKELVNSLEILVASKEKESVLEYLRKLSFAKSIEEKEENGYLLTFEDD
CCEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
IRIKVFIVPPDMFCFYLFYLTGSKDHVQKMETIADDAGYQLTIKGLYKDSSKIKVKNEEE
CEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEECCCHH
IYTTLGVSYIIPELRENRGEITAGFKNCLPDSINLRDIKGDLHIHSSYSDGGFSIREIIE
HHHHHHHHHHHHHHHCCCCCEEECHHHCCCCCCCEEEECCCEEEECCCCCCCCHHHHHHH
AARKKGYEYLAITDHSRSLKVASGLSVDRLFKQIEEIDKLQEEYDDIIIFKGIEVDINKD
HHHHCCCEEEEEECCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEECEEEEECCC
GSLDYSDEVLSYLDFVIASVHTAFNMDRDKMTSRLIKAMENPHVNAIGHPRGRLLKRRDA
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCC
YKIDMDRIIQVASETNTCLEINSSPDRLDIDDVLARKAKEVGVKLVINTDAHHLEELNNM
CEECHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCEEEEEECCHHHHHHHCCC
SLGVAVARRGWLEREDVINTMNAEELQELLRRD
HHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MYQLTNKEVSRILKELAKLMELKGENKFKVRAYYNASRQLINMSDNIQDLAREGKIRNIP
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHCCCCCCHHHHHHCCCCCCCC
GVGEGIARSIKEIMEKGYSPELEELKAELPGGLLEIIKIPGLGPKRAYQLFNELGVTNLE
CCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCHH
ELKSALNTGKARKLKGFGVKTEENLKNKIEKYESFKNTYLLKEALGILDELKRYIKKCPG
HHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VSRVKMTGEARRKKELVNSLEILVASKEKESVLEYLRKLSFAKSIEEKEENGYLLTFEDD
CCEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
IRIKVFIVPPDMFCFYLFYLTGSKDHVQKMETIADDAGYQLTIKGLYKDSSKIKVKNEEE
CEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEECCCHH
IYTTLGVSYIIPELRENRGEITAGFKNCLPDSINLRDIKGDLHIHSSYSDGGFSIREIIE
HHHHHHHHHHHHHHHCCCCCEEECHHHCCCCCCCEEEECCCEEEECCCCCCCCHHHHHHH
AARKKGYEYLAITDHSRSLKVASGLSVDRLFKQIEEIDKLQEEYDDIIIFKGIEVDINKD
HHHHCCCEEEEEECCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEECEEEEECCC
GSLDYSDEVLSYLDFVIASVHTAFNMDRDKMTSRLIKAMENPHVNAIGHPRGRLLKRRDA
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCC
YKIDMDRIIQVASETNTCLEINSSPDRLDIDDVLARKAKEVGVKLVINTDAHHLEELNNM
CEECHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCEEEEEECCHHHHHHHCCC
SLGVAVARRGWLEREDVINTMNAEELQELLRRD
HHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]