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The map label for this gene is cmpR [H]

Identifier: 220931389

GI number: 220931389

Start: 593402

End: 594292

Strand: Reverse

Name: cmpR [H]

Synonym: Hore_05450

Alternate gene names: 220931389

Gene position: 594292-593402 (Counterclockwise)

Preceding gene: 220931392

Following gene: 220931387

Centisome position: 23.05

GC content: 29.85

Gene sequence:

>891_bases
ATGAATTTAAGACAGCTTAAAATATTTGTCATGGTTTGCAAAACAAAAAATATGTCAAAAGCAGCTAAAAAACTATATAT
GTCCCAACCCGCTATCAGTCAAACTATCTCAGAACTTGAAGAAGATTTAAACATAAAACTCTTTGACCGGATTAAAAAAA
GGTTAAAATTAACCTATGCCGGAAAAATCCTTTTACGAAATAGTAAAAGGATTTTAAATCTTGTTGATGAAACTGAAAAT
ATAATAAAGGATATAGTCAATATGAATCAGGGAAAATTACGTATAGGGGCCAGTATGACTATTGGTACCTATCTTTTACC
ACAAATAATAGAAGGGTTTTTAAATAAATATAACAAAATTCACCTACCCTTTACCATTGACAACACCAAAGTAATTGAAG
ATATGATCCTGGATAATAAACTTGATCTGGCTCTGGTAGAAGGTCCTATTTATTGTAAGGACATTTTAGTAGAACATTTC
TTCGATGATCAACTTTATTTAATGTGTTCGTCAAAACACAGTTGGAGTCATAAAAGAAAAATTAATTCAGAAGAACTCAA
AGGTGAAGATTTTATTATAAGGGAAAAAGGCAGTGGTACCAGAGAAACTATTGAAAATATAATGAGAAAACACAGCATAA
AATATCATGTTACCCATGTCTTTAACAATATTGAAGCGATTAAAAGAGCAATAATTTCTAACCTGGGGGTTTCAATCTTA
CCCGAAATCTGCGTTAAAGAAGAACTAAAGAAAGGTTTATTAGTTAAAGTAGATATTCAGGGAATTGAATTTAAAAGAAA
ATTCAGTATCATCTACCACAAAGATAAATACCGTTCTCAACTCTTTAATAATTTTGTTAACCATATATACACAAATATTT
GCAAGTCCTAA

Upstream 100 bases:

>100_bases
ATAGTTAATTTATATATAAACATTGTAATAGTATATTTTTTATTAGTAAAATAATATGTTATTATAATATATATAACCTT
TTACTTATGGAGGAGCTTTT

Downstream 100 bases:

>100_bases
AATCCACATTTCTTTTTTGACTATTTTCCCATAAACCGTTTTATTACTAATTAACCCCTAACTTTTCCCGTTCCTCCTTA
ATTAGGTTTTTGTTAATTCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MNLRQLKIFVMVCKTKNMSKAAKKLYMSQPAISQTISELEEDLNIKLFDRIKKRLKLTYAGKILLRNSKRILNLVDETEN
IIKDIVNMNQGKLRIGASMTIGTYLLPQIIEGFLNKYNKIHLPFTIDNTKVIEDMILDNKLDLALVEGPIYCKDILVEHF
FDDQLYLMCSSKHSWSHKRKINSEELKGEDFIIREKGSGTRETIENIMRKHSIKYHVTHVFNNIEAIKRAIISNLGVSIL
PEICVKEELKKGLLVKVDIQGIEFKRKFSIIYHKDKYRSQLFNNFVNHIYTNICKS

Sequences:

>Translated_296_residues
MNLRQLKIFVMVCKTKNMSKAAKKLYMSQPAISQTISELEEDLNIKLFDRIKKRLKLTYAGKILLRNSKRILNLVDETEN
IIKDIVNMNQGKLRIGASMTIGTYLLPQIIEGFLNKYNKIHLPFTIDNTKVIEDMILDNKLDLALVEGPIYCKDILVEHF
FDDQLYLMCSSKHSWSHKRKINSEELKGEDFIIREKGSGTRETIENIMRKHSIKYHVTHVFNNIEAIKRAIISNLGVSIL
PEICVKEELKKGLLVKVDIQGIEFKRKFSIIYHKDKYRSQLFNNFVNHIYTNICKS
>Mature_296_residues
MNLRQLKIFVMVCKTKNMSKAAKKLYMSQPAISQTISELEEDLNIKLFDRIKKRLKLTYAGKILLRNSKRILNLVDETEN
IIKDIVNMNQGKLRIGASMTIGTYLLPQIIEGFLNKYNKIHLPFTIDNTKVIEDMILDNKLDLALVEGPIYCKDILVEHF
FDDQLYLMCSSKHSWSHKRKINSEELKGEDFIIREKGSGTRETIENIMRKHSIKYHVTHVFNNIEAIKRAIISNLGVSIL
PEICVKEELKKGLLVKVDIQGIEFKRKFSIIYHKDKYRSQLFNNFVNHIYTNICKS

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=288, Percent_Identity=29.5138888888889, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1788748, Length=258, Percent_Identity=25.968992248062, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI157672245, Length=236, Percent_Identity=27.1186440677966, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1790399, Length=276, Percent_Identity=24.2753623188406, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787530, Length=311, Percent_Identity=24.1157556270096, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1789204, Length=301, Percent_Identity=23.2558139534884, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI145693105, Length=287, Percent_Identity=25.7839721254355, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI87082132, Length=293, Percent_Identity=24.9146757679181, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788887, Length=243, Percent_Identity=27.1604938271605, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787879, Length=292, Percent_Identity=25.3424657534247, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787806, Length=241, Percent_Identity=22.4066390041494, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=22.9452054794521, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788297, Length=247, Percent_Identity=21.8623481781377, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87081904, Length=296, Percent_Identity=22.2972972972973, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788296, Length=243, Percent_Identity=24.2798353909465, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790783, Length=259, Percent_Identity=25.0965250965251, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787601, Length=292, Percent_Identity=21.9178082191781, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790262, Length=294, Percent_Identity=19.7278911564626, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789639, Length=120, Percent_Identity=31.6666666666667, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787589, Length=296, Percent_Identity=22.972972972973, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1790208, Length=249, Percent_Identity=22.0883534136546, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1789506, Length=226, Percent_Identity=23.8938053097345, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082024, Length=122, Percent_Identity=35.2459016393443, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87081978, Length=258, Percent_Identity=22.093023255814, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI2367136, Length=104, Percent_Identity=34.6153846153846, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34508; Mature: 34508

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRQLKIFVMVCKTKNMSKAAKKLYMSQPAISQTISELEEDLNIKLFDRIKKRLKLTYA
CCCHHEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GKILLRNSKRILNLVDETENIIKDIVNMNQGKLRIGASMTIGTYLLPQIIEGFLNKYNKI
CEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEE
HLPFTIDNTKVIEDMILDNKLDLALVEGPIYCKDILVEHFFDDQLYLMCSSKHSWSHKRK
EEEEEECCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHC
INSEELKGEDFIIREKGSGTRETIENIMRKHSIKYHVTHVFNNIEAIKRAIISNLGVSIL
CCHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
PEICVKEELKKGLLVKVDIQGIEFKRKFSIIYHKDKYRSQLFNNFVNHIYTNICKS
HHHHHHHHHCCCCEEEEEECCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLRQLKIFVMVCKTKNMSKAAKKLYMSQPAISQTISELEEDLNIKLFDRIKKRLKLTYA
CCCHHEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GKILLRNSKRILNLVDETENIIKDIVNMNQGKLRIGASMTIGTYLLPQIIEGFLNKYNKI
CEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEE
HLPFTIDNTKVIEDMILDNKLDLALVEGPIYCKDILVEHFFDDQLYLMCSSKHSWSHKRK
EEEEEECCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHC
INSEELKGEDFIIREKGSGTRETIENIMRKHSIKYHVTHVFNNIEAIKRAIISNLGVSIL
CCHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
PEICVKEELKKGLLVKVDIQGIEFKRKFSIIYHKDKYRSQLFNNFVNHIYTNICKS
HHHHHHHHHCCCCEEEEEECCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]