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The map label for this gene is citXG [H]

Identifier: 220931315

GI number: 220931315

Start: 503470

End: 504873

Strand: Direct

Name: citXG [H]

Synonym: Hore_04700

Alternate gene names: 220931315

Gene position: 503470-504873 (Clockwise)

Preceding gene: 220931314

Following gene: 220931316

Centisome position: 19.53

GC content: 33.19

Gene sequence:

>1404_bases
ATGGAGGAATTATTAAAAGGTAGAGAGGATAGAGTTAGACAACGTAATAATTTTATCAAATCATTTAAATATAAAGACCC
AGTTTCTTTTGTATCATTAACAGTTAATATTCCTGGCAGGAATAAATTAACTCAATTTGCCAGAGATTTATTTATAGAAG
CCCTAAACAGTCTGCGGTTACATTTATTTATTAAGGGAATTACAAACTGCCAGAAAAAAATTATAAAAAATAAAGCCGGT
TGGACTGGTTTTGTGGCTGTTCCCATTGAGCCTGAAAAATTGAAAAAAATATGTATCTCTATTGAGAAAAACCATTTTAT
AGGTAGGTTATTTGATTTAGATGTATTTGATATAAAAAACCGGTATTATTCAAGAAAAGATTGTGGGCTATCTGATAGAA
GGTGTTTTTTATGTGACCGGCCTGCTAAGGAATGTATCAGGGTAGGAAGGCACGATTATAGGGAGATTGAATTTAAATTA
AGTAAGTTAGAAAAATATTTTTATAAAATGAAATTAAAAAGAGAAGATAATTTTACTAAAGTAATAGGTAATCTCGCTTT
TGAAGCTATAATGAAGGAGTTAATGGTTACTCCAAAACCTGGGTTAGTTGATGCCCAGAGTAGTGGTAGCCATAAAGATA
TGAATTTTGATTTGATGGTAAAAAGTGCGGAGAGTCTTAAACCGTTTTTCTCTAAGTTTGCCATGTTAGGCATTAAACTG
GGAAGACATAGTAAAAACCCACTTACTCGACTAAAAGAGGTTGGACTTGAAGCAGAAGAAAAAATGTTTTCAGTTACAAA
CGGAATTAACACCCACAAGGGTGTTATTTTTTCTCTCGGACTGTTAACAGCAGCAACAGGCTATTTTTATAAAAAAATAA
TATTTAGTGATTATGATTTAGCAGAGAATTTGTGTCACATAGTTTCTGACTGGGTCAGTGGTATTTCTGAAAAAGAACTT
AAAAAGAATCAAAATGAAGGAAATACTCACGGGCAGGTCGTGTATAATGAATATGGATTTAAGGGGGCCAGGGGTGAAGC
TGAAGATGGGTTTCCCAATATTATAAATGTAGGTATACCAGCATATCGCAGGGCAATAAAGAGTAATCTGAGTGAAGAGC
TGGCGGTTCTATCTGTATTAATAAATCTAATGGCCCATGTAAATGATACTAATATTCTTTATAGATCGGGATTAGATACA
TTAAATGAAGTTAAAAGCCTGTCTAGAGAGATAATTTTTTCCGGTGGGGTGGGTACACCAGAAGGCTGGGAAAGATACAA
AAAACTTATTAACTTTGTAGAGAAAAAGAAAGTTAGTCCAGGAGGATCTGCTGATTTACTTATATTGACTATATTTCTTA
ATGAGCTTGAAGAAAAGAAGAGTTTAATATTCACCACTAGTTGA

Upstream 100 bases:

>100_bases
TGAAAAGATTACTGGCTTGATACAGTACCGGGATGGGACTATAATAGATGTAGTTAGAAAAATCTCTGACAGATATTAGG
ATTAAAAAGGGGTTATACTA

Downstream 100 bases:

>100_bases
TTAAGTTATGTGTCGATTACAGAACTAATAATAATATTTAACAATATAATAAAAATATTTCATTCCAGAAAAGAAAAAAA
TATGGTAAAGTTAATAACAA

Product: Triphosphoribosyl-dephospho-CoA synthase

Products: NA

Alternate protein names: Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Apo-ACP nucleodityltransferase; Holo-ACP synthase; Holo-citrate lyase synthase; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase; 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MEELLKGREDRVRQRNNFIKSFKYKDPVSFVSLTVNIPGRNKLTQFARDLFIEALNSLRLHLFIKGITNCQKKIIKNKAG
WTGFVAVPIEPEKLKKICISIEKNHFIGRLFDLDVFDIKNRYYSRKDCGLSDRRCFLCDRPAKECIRVGRHDYREIEFKL
SKLEKYFYKMKLKREDNFTKVIGNLAFEAIMKELMVTPKPGLVDAQSSGSHKDMNFDLMVKSAESLKPFFSKFAMLGIKL
GRHSKNPLTRLKEVGLEAEEKMFSVTNGINTHKGVIFSLGLLTAATGYFYKKIIFSDYDLAENLCHIVSDWVSGISEKEL
KKNQNEGNTHGQVVYNEYGFKGARGEAEDGFPNIINVGIPAYRRAIKSNLSEELAVLSVLINLMAHVNDTNILYRSGLDT
LNEVKSLSREIIFSGGVGTPEGWERYKKLINFVEKKKVSPGGSADLLILTIFLNELEEKKSLIFTTS

Sequences:

>Translated_467_residues
MEELLKGREDRVRQRNNFIKSFKYKDPVSFVSLTVNIPGRNKLTQFARDLFIEALNSLRLHLFIKGITNCQKKIIKNKAG
WTGFVAVPIEPEKLKKICISIEKNHFIGRLFDLDVFDIKNRYYSRKDCGLSDRRCFLCDRPAKECIRVGRHDYREIEFKL
SKLEKYFYKMKLKREDNFTKVIGNLAFEAIMKELMVTPKPGLVDAQSSGSHKDMNFDLMVKSAESLKPFFSKFAMLGIKL
GRHSKNPLTRLKEVGLEAEEKMFSVTNGINTHKGVIFSLGLLTAATGYFYKKIIFSDYDLAENLCHIVSDWVSGISEKEL
KKNQNEGNTHGQVVYNEYGFKGARGEAEDGFPNIINVGIPAYRRAIKSNLSEELAVLSVLINLMAHVNDTNILYRSGLDT
LNEVKSLSREIIFSGGVGTPEGWERYKKLINFVEKKKVSPGGSADLLILTIFLNELEEKKSLIFTTS
>Mature_467_residues
MEELLKGREDRVRQRNNFIKSFKYKDPVSFVSLTVNIPGRNKLTQFARDLFIEALNSLRLHLFIKGITNCQKKIIKNKAG
WTGFVAVPIEPEKLKKICISIEKNHFIGRLFDLDVFDIKNRYYSRKDCGLSDRRCFLCDRPAKECIRVGRHDYREIEFKL
SKLEKYFYKMKLKREDNFTKVIGNLAFEAIMKELMVTPKPGLVDAQSSGSHKDMNFDLMVKSAESLKPFFSKFAMLGIKL
GRHSKNPLTRLKEVGLEAEEKMFSVTNGINTHKGVIFSLGLLTAATGYFYKKIIFSDYDLAENLCHIVSDWVSGISEKEL
KKNQNEGNTHGQVVYNEYGFKGARGEAEDGFPNIINVGIPAYRRAIKSNLSEELAVLSVLINLMAHVNDTNILYRSGLDT
LNEVKSLSREIIFSGGVGTPEGWERYKKLINFVEKKKVSPGGSADLLILTIFLNELEEKKSLIFTTS

Specific function: Bifunctional enzyme that catalyzes formation of 2-(5''- triphosphoribosyl)-3'-dephosphocoenzyme-A, and then the transfer of this prosthetic group precursor to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield the holo-acyl carrier p

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the CitG/MdcB family [H]

Homologues:

Organism=Escherichia coli, GI1786830, Length=273, Percent_Identity=36.2637362637363, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1786831, Length=163, Percent_Identity=28.8343558282209, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002736
- InterPro:   IPR005551
- InterPro:   IPR017551 [H]

Pfam domain/function: PF01874 CitG; PF03802 CitX [H]

EC number: =2.7.7.61; =2.7.8.25 [H]

Molecular weight: Translated: 53263; Mature: 53263

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEELLKGREDRVRQRNNFIKSFKYKDPVSFVSLTVNIPGRNKLTQFARDLFIEALNSLRL
CCHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
HLFIKGITNCQKKIIKNKAGWTGFVAVPIEPEKLKKICISIEKNHFIGRLFDLDVFDIKN
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHH
RYYSRKDCGLSDRRCFLCDRPAKECIRVGRHDYREIEFKLSKLEKYFYKMKLKREDNFTK
HHCCCCCCCCCCCEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VIGNLAFEAIMKELMVTPKPGLVDAQSSGSHKDMNFDLMVKSAESLKPFFSKFAMLGIKL
HHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
GRHSKNPLTRLKEVGLEAEEKMFSVTNGINTHKGVIFSLGLLTAATGYFYKKIIFSDYDL
CCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
AENLCHIVSDWVSGISEKELKKNQNEGNTHGQVVYNEYGFKGARGEAEDGFPNIINVGIP
HHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCH
AYRRAIKSNLSEELAVLSVLINLMAHVNDTNILYRSGLDTLNEVKSLSREIIFSGGVGTP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHEEECCCCCC
EGWERYKKLINFVEKKKVSPGGSADLLILTIFLNELEEKKSLIFTTS
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEEECC
>Mature Secondary Structure
MEELLKGREDRVRQRNNFIKSFKYKDPVSFVSLTVNIPGRNKLTQFARDLFIEALNSLRL
CCHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
HLFIKGITNCQKKIIKNKAGWTGFVAVPIEPEKLKKICISIEKNHFIGRLFDLDVFDIKN
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHH
RYYSRKDCGLSDRRCFLCDRPAKECIRVGRHDYREIEFKLSKLEKYFYKMKLKREDNFTK
HHCCCCCCCCCCCEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VIGNLAFEAIMKELMVTPKPGLVDAQSSGSHKDMNFDLMVKSAESLKPFFSKFAMLGIKL
HHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
GRHSKNPLTRLKEVGLEAEEKMFSVTNGINTHKGVIFSLGLLTAATGYFYKKIIFSDYDL
CCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
AENLCHIVSDWVSGISEKELKKNQNEGNTHGQVVYNEYGFKGARGEAEDGFPNIINVGIP
HHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCH
AYRRAIKSNLSEELAVLSVLINLMAHVNDTNILYRSGLDTLNEVKSLSREIIFSGGVGTP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHEEECCCCCC
EGWERYKKLINFVEKKKVSPGGSADLLILTIFLNELEEKKSLIFTTS
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]