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The map label for this gene is malE [C]

Identifier: 220931306

GI number: 220931306

Start: 493986

End: 495281

Strand: Direct

Name: malE [C]

Synonym: Hore_04610

Alternate gene names: 220931306

Gene position: 493986-495281 (Clockwise)

Preceding gene: 220931305

Following gene: 220931307

Centisome position: 19.16

GC content: 38.97

Gene sequence:

>1296_bases
GTGAAAAAACTATTACTTTTGTTAATGGTGGTTAGTTTATTGGCAGGGGTAGCTGCGACAGGGTTGGTTATGGCAAAAGA
ACCAATTGAAATTAAGTTTGTTAGTCTGGCCTGGCAAAAGCAATCTATTGAGGCTAATAAAGAAATTGTAGCTGAGTGGA
ATAGAACTCACCCTGATGTACAGGTAAAATATATTCAGGGGACATGGGGTTCAATCCATGATTATATGATTACTGCTTTT
GAAACAGGTTCTGTACCTGATGTTTTTCACTATGAATCTGCTGCGATAGTGGGTTTTGCCCAAAAGGGGTATCTGGCAGA
ACTTAATTCATTAATGTCTGAAGATTTAAAGAATGACATACTTGATGAAGCCTGGAAGACTACCCAGCTTGAAAATGGTA
AAATCTATGGTGTACCATTCCTGTGGGAATCTCAGATTACATTATATAACAAAGCCCTGTTTAAAGAAGCCGGGATTACT
CCACCAACTATTGATAATCCATGGACCTGGGAAGACTTAAGAGAAGCTGCTAAAAAGCTGACCAAAGATACTGATAATGA
CGGTGAAATTGATCAATGGGGTGTTGGTTTAGGTTTAAAAAGTCCGGCTAAAAAAATGCTCAGATTATCTGTGGGCTTTG
GTGGAAAGTTCTTTAAAAAGGAAAATGGTGAATATCATGTTGAGGTAGGGGAAGCAGAAAAGAAATTGTTAAAACAGTTT
TATGCTATGCTCTATGAAGATAAAACAGCTCCTCTATCAGGTATAGGTCAATCAGGTAGTAGTATGATTCCTGGTTTTCT
TGCCGGTAAATATGCAATGGTACCCAGTGTTGGTGTCTGGGCCAGGCAGCAGGTTGTTGTTAATGCCCCTGAAAATTTTG
AATGGGGAGTAATTCCCCCAATTAAGGCCAAAACTCAGGCCCAGGGTGTTGGTACCCAGACTTTAAGTATTCCATCTGCA
TCTAAATATAAAAAAGAAGCCATGGAATTTATTGAATTTTTCTTGAACACCAGGAATATGGCAAGACTGGCAAAAGGAGA
CTGGATGCTTCCTACCAGAAAATCAACTATGAATTTACCTATGTTCCAGACCGATGAAAATGGCTGGAAGGTTGCCATGA
ATTCAGCTAAGTGTCTTGAAGCAGGTCCCTGGCAAAATATACCAGGATTTCCTGAATGGAAAAACAGGGTTGGTAATCCA
GTTATTCAGCTATACTTAAAAGATAAAATATCATTAGAAGATGCTGCTAAAAGGCTAGAGAGAGAAGGAAACAGGATCCT
GCAACGTTATAAATAA

Upstream 100 bases:

>100_bases
TTTTGGTTTTTTACAGAAGTGGCTGGTTTCTGGACTAACAAGTGGTGCAGTTAAGTATTAAATAAATTTATAATATTAGA
AAAAGGGGGACAAATTAACT

Downstream 100 bases:

>100_bases
AGGAGATTGAAATAATCTATGACAGTAAAAAAAGACAAAGCTCTGGGAGCTTTGGTTGGTCTGGCCGTGGGTGATGCCCT
CGGCCAGCCGACTGAAGGAA

Product: family 1 extracellular solute-binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MKKLLLLLMVVSLLAGVAATGLVMAKEPIEIKFVSLAWQKQSIEANKEIVAEWNRTHPDVQVKYIQGTWGSIHDYMITAF
ETGSVPDVFHYESAAIVGFAQKGYLAELNSLMSEDLKNDILDEAWKTTQLENGKIYGVPFLWESQITLYNKALFKEAGIT
PPTIDNPWTWEDLREAAKKLTKDTDNDGEIDQWGVGLGLKSPAKKMLRLSVGFGGKFFKKENGEYHVEVGEAEKKLLKQF
YAMLYEDKTAPLSGIGQSGSSMIPGFLAGKYAMVPSVGVWARQQVVVNAPENFEWGVIPPIKAKTQAQGVGTQTLSIPSA
SKYKKEAMEFIEFFLNTRNMARLAKGDWMLPTRKSTMNLPMFQTDENGWKVAMNSAKCLEAGPWQNIPGFPEWKNRVGNP
VIQLYLKDKISLEDAAKRLEREGNRILQRYK

Sequences:

>Translated_431_residues
MKKLLLLLMVVSLLAGVAATGLVMAKEPIEIKFVSLAWQKQSIEANKEIVAEWNRTHPDVQVKYIQGTWGSIHDYMITAF
ETGSVPDVFHYESAAIVGFAQKGYLAELNSLMSEDLKNDILDEAWKTTQLENGKIYGVPFLWESQITLYNKALFKEAGIT
PPTIDNPWTWEDLREAAKKLTKDTDNDGEIDQWGVGLGLKSPAKKMLRLSVGFGGKFFKKENGEYHVEVGEAEKKLLKQF
YAMLYEDKTAPLSGIGQSGSSMIPGFLAGKYAMVPSVGVWARQQVVVNAPENFEWGVIPPIKAKTQAQGVGTQTLSIPSA
SKYKKEAMEFIEFFLNTRNMARLAKGDWMLPTRKSTMNLPMFQTDENGWKVAMNSAKCLEAGPWQNIPGFPEWKNRVGNP
VIQLYLKDKISLEDAAKRLEREGNRILQRYK
>Mature_431_residues
MKKLLLLLMVVSLLAGVAATGLVMAKEPIEIKFVSLAWQKQSIEANKEIVAEWNRTHPDVQVKYIQGTWGSIHDYMITAF
ETGSVPDVFHYESAAIVGFAQKGYLAELNSLMSEDLKNDILDEAWKTTQLENGKIYGVPFLWESQITLYNKALFKEAGIT
PPTIDNPWTWEDLREAAKKLTKDTDNDGEIDQWGVGLGLKSPAKKMLRLSVGFGGKFFKKENGEYHVEVGEAEKKLLKQF
YAMLYEDKTAPLSGIGQSGSSMIPGFLAGKYAMVPSVGVWARQQVVVNAPENFEWGVIPPIKAKTQAQGVGTQTLSIPSA
SKYKKEAMEFIEFFLNTRNMARLAKGDWMLPTRKSTMNLPMFQTDENGWKVAMNSAKCLEAGPWQNIPGFPEWKNRVGNP
VIQLYLKDKISLEDAAKRLEREGNRILQRYK

Specific function: May participate in oleandomycin glycosylation and secretion during antibiotic production [H]

COG id: COG1653

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 48427; Mature: 48427

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLLLLMVVSLLAGVAATGLVMAKEPIEIKFVSLAWQKQSIEANKEIVAEWNRTHPDV
CHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEEEHHHHHHHCCHHHHHHCCCCCCCE
QVKYIQGTWGSIHDYMITAFETGSVPDVFHYESAAIVGFAQKGYLAELNSLMSEDLKNDI
EEEEEECCCCCHHHEEEEEEECCCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHH
LDEAWKTTQLENGKIYGVPFLWESQITLYNKALFKEAGITPPTIDNPWTWEDLREAAKKL
HHHHHHHCCCCCCEEEEECEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
TKDTDNDGEIDQWGVGLGLKSPAKKMLRLSVGFGGKFFKKENGEYHVEVGEAEKKLLKQF
HCCCCCCCCCCHHCCCCCCCCHHHHHHEECCCCCCEEEECCCCCEEEEECHHHHHHHHHH
YAMLYEDKTAPLSGIGQSGSSMIPGFLAGKYAMVPSVGVWARQQVVVNAPENFEWGVIPP
HHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCC
IKAKTQAQGVGTQTLSIPSASKYKKEAMEFIEFFLNTRNMARLAKGDWMLPTRKSTMNLP
CCCCCHHCCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCC
MFQTDENGWKVAMNSAKCLEAGPWQNIPGFPEWKNRVGNPVIQLYLKDKISLEDAAKRLE
EEEECCCCCEEEECCCHHCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCHHHHHHHHH
REGNRILQRYK
HHHHHHHHHCC
>Mature Secondary Structure
MKKLLLLLMVVSLLAGVAATGLVMAKEPIEIKFVSLAWQKQSIEANKEIVAEWNRTHPDV
CHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEEEHHHHHHHCCHHHHHHCCCCCCCE
QVKYIQGTWGSIHDYMITAFETGSVPDVFHYESAAIVGFAQKGYLAELNSLMSEDLKNDI
EEEEEECCCCCHHHEEEEEEECCCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHH
LDEAWKTTQLENGKIYGVPFLWESQITLYNKALFKEAGITPPTIDNPWTWEDLREAAKKL
HHHHHHHCCCCCCEEEEECEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
TKDTDNDGEIDQWGVGLGLKSPAKKMLRLSVGFGGKFFKKENGEYHVEVGEAEKKLLKQF
HCCCCCCCCCCHHCCCCCCCCHHHHHHEECCCCCCEEEECCCCCEEEEECHHHHHHHHHH
YAMLYEDKTAPLSGIGQSGSSMIPGFLAGKYAMVPSVGVWARQQVVVNAPENFEWGVIPP
HHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCC
IKAKTQAQGVGTQTLSIPSASKYKKEAMEFIEFFLNTRNMARLAKGDWMLPTRKSTMNLP
CCCCCHHCCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCC
MFQTDENGWKVAMNSAKCLEAGPWQNIPGFPEWKNRVGNPVIQLYLKDKISLEDAAKRLE
EEEECCCCCEEEECCCHHCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCHHHHHHHHH
REGNRILQRYK
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8244027 [H]