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The map label for this gene is sigW [H]

Identifier: 220931243

GI number: 220931243

Start: 407226

End: 407813

Strand: Direct

Name: sigW [H]

Synonym: Hore_03970

Alternate gene names: 220931243

Gene position: 407226-407813 (Clockwise)

Preceding gene: 220931241

Following gene: 220931244

Centisome position: 15.8

GC content: 40.99

Gene sequence:

>588_bases
TTGGATGGAACATCTGATGAGAAGATAATCAATATGATTTTAGCTGGAGAAAAAGAACTGTTTGCCAGGCTGGTGGAAAA
ATATCAGAGAAAAGTCTATAATACCACCTACCGGATGTTAGGCAACAGTGAAGATGCCAGTGACCTGACCCAGGAGGCCT
TTATAAAAACCTTCAGGAATCTGAAACGGTTTAGAGGGAAGGCCAGTTTTTCAACCTGGCTTTTTACCATAACAACAAAT
TTGTGCCGGGACGAGCTGCGGAAACGTCAGCGTCGTAGTGCTAGTCCCCATTTCCCTGATGGGCAACATTTTATGAGTGA
GGATATTGAAAACATCAAAGATAATTCAAAAGTTCCCGAAGACCTCTACATGGGTAGGGAAACCATGGCTTCAATCCAGA
GGGCTATTAATAAATTACCAGCTGATCAAAAAGAAGTAATAGTGTTAAGAGATATACAGGGGTTTAGCTATAAAGAGATT
TCAGAAATTATAGGAGTTCCGATGGGAACTGTTAAATCGCGTTTGAGCAGGGCCAGGAAGTCTTTACAGAAACACCTCAA
AAATATAGAAGGGAGGGGTTTAAAATGA

Upstream 100 bases:

>100_bases
TTAGATACCTGGATGTAAGGAGATTAATAAAAAAATTAAGTTGGACATGGAACATTATATTTACTGATACGTCTAAATAA
ATAGAAAGGGGTGAAGGAGA

Downstream 100 bases:

>100_bases
ATCATCAGAAACTTAAAGACCTTTTACCCCTGTATGTGGATAACGGGTTGAATGATGAGGAGAAAAACCTGGTGGAAAAA
CATTTAAAAGAATGTGAGGA

Product: ECF subfamily RNA polymerase sigma-24 subunit

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MDGTSDEKIINMILAGEKELFARLVEKYQRKVYNTTYRMLGNSEDASDLTQEAFIKTFRNLKRFRGKASFSTWLFTITTN
LCRDELRKRQRRSASPHFPDGQHFMSEDIENIKDNSKVPEDLYMGRETMASIQRAINKLPADQKEVIVLRDIQGFSYKEI
SEIIGVPMGTVKSRLSRARKSLQKHLKNIEGRGLK

Sequences:

>Translated_195_residues
MDGTSDEKIINMILAGEKELFARLVEKYQRKVYNTTYRMLGNSEDASDLTQEAFIKTFRNLKRFRGKASFSTWLFTITTN
LCRDELRKRQRRSASPHFPDGQHFMSEDIENIKDNSKVPEDLYMGRETMASIQRAINKLPADQKEVIVLRDIQGFSYKEI
SEIIGVPMGTVKSRLSRARKSLQKHLKNIEGRGLK
>Mature_195_residues
MDGTSDEKIINMILAGEKELFARLVEKYQRKVYNTTYRMLGNSEDASDLTQEAFIKTFRNLKRFRGKASFSTWLFTITTN
LCRDELRKRQRRSASPHFPDGQHFMSEDIENIKDNSKVPEDLYMGRETMASIQRAINKLPADQKEVIVLRDIQGFSYKEI
SEIIGVPMGTVKSRLSRARKSLQKHLKNIEGRGLK

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=188, Percent_Identity=35.1063829787234, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 22595; Mature: 22595

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGTSDEKIINMILAGEKELFARLVEKYQRKVYNTTYRMLGNSEDASDLTQEAFIKTFRN
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LKRFRGKASFSTWLFTITTNLCRDELRKRQRRSASPHFPDGQHFMSEDIENIKDNSKVPE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCH
DLYMGRETMASIQRAINKLPADQKEVIVLRDIQGFSYKEISEIIGVPMGTVKSRLSRARK
HHHHCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
SLQKHLKNIEGRGLK
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MDGTSDEKIINMILAGEKELFARLVEKYQRKVYNTTYRMLGNSEDASDLTQEAFIKTFRN
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LKRFRGKASFSTWLFTITTNLCRDELRKRQRRSASPHFPDGQHFMSEDIENIKDNSKVPE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCH
DLYMGRETMASIQRAINKLPADQKEVIVLRDIQGFSYKEISEIIGVPMGTVKSRLSRARK
HHHHCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
SLQKHLKNIEGRGLK
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]