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The map label for this gene is hypA [H]

Identifier: 220931233

GI number: 220931233

Start: 398661

End: 399008

Strand: Direct

Name: hypA [H]

Synonym: Hore_03870

Alternate gene names: 220931233

Gene position: 398661-399008 (Clockwise)

Preceding gene: 220931232

Following gene: 220931234

Centisome position: 15.46

GC content: 35.92

Gene sequence:

>348_bases
ATGTCTGTCATGGGGGAGATTTTTTCAATAATAAACAGTAATGTAGCTAAATACAGACTTAAAAGAGTAACAAAAGTAGT
GGTCAGAGTTGGGGAAATGACCTGCCTTAATGATGAAGCACTGGATTTTGCTTTTCAGGTATTTGCTGAGGATACCGTAG
CTGAAGGAGCCGAACTTATTATTAATAAAGAAAAAGCCAGGGCAAGATGCCATCACTGTGGTCATATTTTTGAAATAACC
TATACTGATAAGTTATGCCCCCATTGTCAAAGTTACAGTGATAATATTGTAAATGGGTATGAATTATATCTTGATAAAGT
GGAGGGGGAGATAGATGAAAACGATTAA

Upstream 100 bases:

>100_bases
CCTTTGATCCCTGTATATCCTGTGGTACCCATGTCTATAGTATTGACGGTAAATTGCAGAAGAAAATAGAATTTTGAAAG
TAGTGGTTAAATTGCATGAA

Downstream 100 bases:

>100_bases
AATAAATAAAAAAATCCTGAGCAAAAATGAAGAAAAGGCTACAGAAATCAGGGCATATCTTAATGAGAAAAAGGTCAGGA
TGTTAAATCTGGTGGGGTCA

Product: hydrogenase nickel insertion protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 115; Mature: 114

Protein sequence:

>115_residues
MSVMGEIFSIINSNVAKYRLKRVTKVVVRVGEMTCLNDEALDFAFQVFAEDTVAEGAELIINKEKARARCHHCGHIFEIT
YTDKLCPHCQSYSDNIVNGYELYLDKVEGEIDEND

Sequences:

>Translated_115_residues
MSVMGEIFSIINSNVAKYRLKRVTKVVVRVGEMTCLNDEALDFAFQVFAEDTVAEGAELIINKEKARARCHHCGHIFEIT
YTDKLCPHCQSYSDNIVNGYELYLDKVEGEIDEND
>Mature_114_residues
SVMGEIFSIINSNVAKYRLKRVTKVVVRVGEMTCLNDEALDFAFQVFAEDTVAEGAELIINKEKARARCHHCGHIFEITY
TDKLCPHCQSYSDNIVNGYELYLDKVEGEIDEND

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789365, Length=110, Percent_Identity=30, Blast_Score=65, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538
- InterPro:   IPR004039 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 13081; Mature: 12950

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVMGEIFSIINSNVAKYRLKRVTKVVVRVGEMTCLNDEALDFAFQVFAEDTVAEGAELI
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHCCHHHE
INKEKARARCHHCGHIFEITYTDKLCPHCQSYSDNIVNGYELYLDKVEGEIDEND
EECHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SVMGEIFSIINSNVAKYRLKRVTKVVVRVGEMTCLNDEALDFAFQVFAEDTVAEGAELI
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHCCHHHE
INKEKARARCHHCGHIFEITYTDKLCPHCQSYSDNIVNGYELYLDKVEGEIDEND
EECHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]