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The map label for this gene is dhaK [H]

Identifier: 220931173

GI number: 220931173

Start: 335101

End: 336105

Strand: Direct

Name: dhaK [H]

Synonym: Hore_03250

Alternate gene names: 220931173

Gene position: 335101-336105 (Clockwise)

Preceding gene: 220931172

Following gene: 220931174

Centisome position: 13.0

GC content: 37.51

Gene sequence:

>1005_bases
ATGCAAAAGTTTGTAAATGATCCCAGTCAGGTAGTAGATGAAATGTTAGAGGGATTTGTTAAAAATCATAAAGATCTAGT
TGCCAAAACTGATAATCCCAGGGTTTTAAAATATGTTAAGGCTCCTATTGAAAATAAAGTGGGGATAGTTACCGGTGGAG
GTTCTGGTCACAAACCGGCTTTTATAGGGTATATTGGCAAAAATATGGTTGATGCTGTAGCCGTCGGAGAAATATTTTCA
TCTCCTACTGCCCAGGCTTTTTATGATGCTTTTAAAGAAGCTGATTCTGGTAAAGGTGTTGCCTGCTTATTTGGTAATTA
TGCTGGGGATAAAATGAATGTAAAAATGGCTATAGAAATGGCAAAAGAAGATGGAATAGATGTGAAAACAGTTATAGCAA
ATGATGATGTGCCGTCTGCACCTAAAGATGAAAGGGAAAAGCGCCGTGGTGTAGCCGGTGAAATTTTAATGTGGAAAGTA
GGGGGAGCTAAAGCTGCAACTGGAGCGAGTCTGGATGAGGTTATTTCTACCTGCCAGAAAGCAATAGATAATACCAGAAG
TATTGGAGTTGGATTATCACCGTGTACTATTCCAGAAGTAGGCAAACCCAATTTTACGATTGAAGAAGGAAAAATGGAAG
TAGGAATTGGTCATCATGGTGAACCCGGTGTTAAGGTATCTGAAATTAAACCTGCTAAAGAAGTTGCAAAAGAAATGGTG
AACTATGTACTCCCTGATCTTCCCTTTGAGAAAGGTAATGAAGTTGCTGTTCTAGTTTCAGGATTAGGAGCTACACCTGT
TTTAGAACTCTATATTCTTTATAACGAGATTGAAAAGTTATTAAAGAAAGAAAGTATTAAAATTTATAAATCATATGTAG
GCAATTACTTTACATCACTGGATATGGCGGGCGCAACCCTTACTGTGATGAAACTTGATGAAGAATTAAAAGAATTGCTT
GATGAAGAGGCCAATTGTATGGGACTTAAACAATTTAAGGGGTGA

Upstream 100 bases:

>100_bases
TGTACCATAAATGAATAGACTAACCTCATAGTATAGCAAAAAAATAATATTATCTTAAATAATGGAGAGAGACTAATATA
GGATTGGAGGTAAAAAGGTT

Downstream 100 bases:

>100_bases
GGGCCATGGAATATTTTTTAAATAGTAGTGGGGGCAGGATTGTTTACAGTATTATAGAGGCAATTCAGGATAATAAGGAA
TATCTGAGTGAAATAGATGG

Product: glycerone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MQKFVNDPSQVVDEMLEGFVKNHKDLVAKTDNPRVLKYVKAPIENKVGIVTGGGSGHKPAFIGYIGKNMVDAVAVGEIFS
SPTAQAFYDAFKEADSGKGVACLFGNYAGDKMNVKMAIEMAKEDGIDVKTVIANDDVPSAPKDEREKRRGVAGEILMWKV
GGAKAATGASLDEVISTCQKAIDNTRSIGVGLSPCTIPEVGKPNFTIEEGKMEVGIGHHGEPGVKVSEIKPAKEVAKEMV
NYVLPDLPFEKGNEVAVLVSGLGATPVLELYILYNEIEKLLKKESIKIYKSYVGNYFTSLDMAGATLTVMKLDEELKELL
DEEANCMGLKQFKG

Sequences:

>Translated_334_residues
MQKFVNDPSQVVDEMLEGFVKNHKDLVAKTDNPRVLKYVKAPIENKVGIVTGGGSGHKPAFIGYIGKNMVDAVAVGEIFS
SPTAQAFYDAFKEADSGKGVACLFGNYAGDKMNVKMAIEMAKEDGIDVKTVIANDDVPSAPKDEREKRRGVAGEILMWKV
GGAKAATGASLDEVISTCQKAIDNTRSIGVGLSPCTIPEVGKPNFTIEEGKMEVGIGHHGEPGVKVSEIKPAKEVAKEMV
NYVLPDLPFEKGNEVAVLVSGLGATPVLELYILYNEIEKLLKKESIKIYKSYVGNYFTSLDMAGATLTVMKLDEELKELL
DEEANCMGLKQFKG
>Mature_334_residues
MQKFVNDPSQVVDEMLEGFVKNHKDLVAKTDNPRVLKYVKAPIENKVGIVTGGGSGHKPAFIGYIGKNMVDAVAVGEIFS
SPTAQAFYDAFKEADSGKGVACLFGNYAGDKMNVKMAIEMAKEDGIDVKTVIANDDVPSAPKDEREKRRGVAGEILMWKV
GGAKAATGASLDEVISTCQKAIDNTRSIGVGLSPCTIPEVGKPNFTIEEGKMEVGIGHHGEPGVKVSEIKPAKEVAKEMV
NYVLPDLPFEKGNEVAVLVSGLGATPVLELYILYNEIEKLLKKESIKIYKSYVGNYFTSLDMAGATLTVMKLDEELKELL
DEEANCMGLKQFKG

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=329, Percent_Identity=32.2188449848024, Blast_Score=182, Evalue=4e-46,
Organism=Escherichia coli, GI87081857, Length=345, Percent_Identity=35.9420289855072, Blast_Score=233, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17565018, Length=329, Percent_Identity=32.5227963525836, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6321055, Length=346, Percent_Identity=30.9248554913295, Blast_Score=151, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6323570, Length=345, Percent_Identity=30.4347826086957, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 36042; Mature: 36042

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKFVNDPSQVVDEMLEGFVKNHKDLVAKTDNPRVLKYVKAPIENKVGIVTGGGSGHKPA
CCCCCCCHHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHCCCCCCCEEEECCCCCCCCE
FIGYIGKNMVDAVAVGEIFSSPTAQAFYDAFKEADSGKGVACLFGNYAGDKMNVKMAIEM
EEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEEE
AKEDGIDVKTVIANDDVPSAPKDEREKRRGVAGEILMWKVGGAKAATGASLDEVISTCQK
HHCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
AIDNTRSIGVGLSPCTIPEVGKPNFTIEEGKMEVGIGHHGEPGVKVSEIKPAKEVAKEMV
HHCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEECCCCCCCCCCEECCCCCHHHHHHHHH
NYVLPDLPFEKGNEVAVLVSGLGATPVLELYILYNEIEKLLKKESIKIYKSYVGNYFTSL
HHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMAGATLTVMKLDEELKELLDEEANCMGLKQFKG
HCCCCEEEEHHHHHHHHHHHCCCCCCCCHHHCCC
>Mature Secondary Structure
MQKFVNDPSQVVDEMLEGFVKNHKDLVAKTDNPRVLKYVKAPIENKVGIVTGGGSGHKPA
CCCCCCCHHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHCCCCCCCEEEECCCCCCCCE
FIGYIGKNMVDAVAVGEIFSSPTAQAFYDAFKEADSGKGVACLFGNYAGDKMNVKMAIEM
EEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEEE
AKEDGIDVKTVIANDDVPSAPKDEREKRRGVAGEILMWKVGGAKAATGASLDEVISTCQK
HHCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
AIDNTRSIGVGLSPCTIPEVGKPNFTIEEGKMEVGIGHHGEPGVKVSEIKPAKEVAKEMV
HHCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEECCCCCCCCCCEECCCCCHHHHHHHHH
NYVLPDLPFEKGNEVAVLVSGLGATPVLELYILYNEIEKLLKKESIKIYKSYVGNYFTSL
HHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMAGATLTVMKLDEELKELLDEEANCMGLKQFKG
HCCCCEEEEHHHHHHHHHHHCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]