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The map label for this gene is gatR [H]

Identifier: 220931171

GI number: 220931171

Start: 332359

End: 333132

Strand: Reverse

Name: gatR [H]

Synonym: Hore_03230

Alternate gene names: 220931171

Gene position: 333132-332359 (Counterclockwise)

Preceding gene: 220931185

Following gene: 220931161

Centisome position: 12.92

GC content: 33.98

Gene sequence:

>774_bases
ATGCTATCAATTGCCAGGAGAAACAAAATACTAGAAATTTTAAAAGAAAAACATCAGATTACAACACAAGAACTCGAAAA
GGAACTTAATGTTTCCGGAGCAACTGTAAGAAATGATCTTCAGGAACTTGAAAAAGAAGGGTTATTAAAACGTATTCATG
GAGGAGCTGTTCTTCCAAAAGAACAGATTTTCCAAAATAGCTACAGGAATTTTCACCACAGAAGCAAAAAAAACGTTCAG
GAAAAAAAGGCTATCTGCCGTGCTGCTTCAAAATTTATTGATGAAGGACAGACATATCTCCTCGATGCCAGTTCAACTGT
ATTATATTTAGTACCTTATCTAAGGGAAAAACATAGGATAAGTATTGCCACAAATGGACTTTATACAGCTCTTGAAGTGA
AGGAAATTTGTAATATCAATGTTATTGTCCTGGGAGGTATTGCTAAACCACGGTCAGGTTCCCTGGAAGGATTATTGGGA
GAATCGATATTATGTAAAATCAATGCCGATATTATGTTTACCTCTGCTCATGGTTTTACCCTTAAAGACGGCCTAACAGA
TTTTAATGTTTATGAAGTAGAATTAAAGAATAAAATGGTTTCAAAGTCCAAAAAAGTAATTGCCCTTCTGGACCATACAA
AGATAGGGTATACCTCTACTACAAGCTTCTGTAGTATAGATAATCTAGATGTAATAGTTACTGATAATAAAACTCCTTCC
AATAAAATAGAAGAAATAAGAAATGCCGGTATTGAAGTAATTGTAGCTGAATAA

Upstream 100 bases:

>100_bases
AACATTTTTTTGTACTTTATCCATTCTTAGGGTTTATAATTATTAATGGTTAATTTTTTAATATTAGAATACTAAAATAT
ATATTAAAGGATGATGCCTA

Downstream 100 bases:

>100_bases
TAATAAAAAAAACAACGTCTGGTATGATTACCAGACGTTGTCTAATTTTTTATAATTATTTAATTTATATCTAATAATTA
TTATCACAGGGTAAATTATC

Product: transcriptional regulator, DeoR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLSIARRNKILEILKEKHQITTQELEKELNVSGATVRNDLQELEKEGLLKRIHGGAVLPKEQIFQNSYRNFHHRSKKNVQ
EKKAICRAASKFIDEGQTYLLDASSTVLYLVPYLREKHRISIATNGLYTALEVKEICNINVIVLGGIAKPRSGSLEGLLG
ESILCKINADIMFTSAHGFTLKDGLTDFNVYEVELKNKMVSKSKKVIALLDHTKIGYTSTTSFCSIDNLDVIVTDNKTPS
NKIEEIRNAGIEVIVAE

Sequences:

>Translated_257_residues
MLSIARRNKILEILKEKHQITTQELEKELNVSGATVRNDLQELEKEGLLKRIHGGAVLPKEQIFQNSYRNFHHRSKKNVQ
EKKAICRAASKFIDEGQTYLLDASSTVLYLVPYLREKHRISIATNGLYTALEVKEICNINVIVLGGIAKPRSGSLEGLLG
ESILCKINADIMFTSAHGFTLKDGLTDFNVYEVELKNKMVSKSKKVIALLDHTKIGYTSTTSFCSIDNLDVIVTDNKTPS
NKIEEIRNAGIEVIVAE
>Mature_257_residues
MLSIARRNKILEILKEKHQITTQELEKELNVSGATVRNDLQELEKEGLLKRIHGGAVLPKEQIFQNSYRNFHHRSKKNVQ
EKKAICRAASKFIDEGQTYLLDASSTVLYLVPYLREKHRISIATNGLYTALEVKEICNINVIVLGGIAKPRSGSLEGLLG
ESILCKINADIMFTSAHGFTLKDGLTDFNVYEVELKNKMVSKSKKVIALLDHTKIGYTSTTSFCSIDNLDVIVTDNKTPS
NKIEEIRNAGIEVIVAE

Specific function: Repressor of the gat operon for galacticol transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=252, Percent_Identity=32.9365079365079, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1788069, Length=254, Percent_Identity=29.1338582677165, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789829, Length=258, Percent_Identity=29.0697674418605, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789519, Length=250, Percent_Identity=26.4, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI87082344, Length=252, Percent_Identity=25.7936507936508, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI226510968, Length=257, Percent_Identity=26.0700389105058, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789170, Length=236, Percent_Identity=28.8135593220339, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1790635, Length=252, Percent_Identity=27.7777777777778, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1787540, Length=254, Percent_Identity=24.4094488188976, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790753, Length=259, Percent_Identity=23.1660231660232, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787063, Length=230, Percent_Identity=22.6086956521739, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28772; Mature: 28772

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIARRNKILEILKEKHQITTQELEKELNVSGATVRNDLQELEKEGLLKRIHGGAVLPK
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCH
EQIFQNSYRNFHHRSKKNVQEKKAICRAASKFIDEGQTYLLDASSTVLYLVPYLREKHRI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEHHHCCCCEE
SIATNGLYTALEVKEICNINVIVLGGIAKPRSGSLEGLLGESILCKINADIMFTSAHGFT
EEEECCEEEHEEHHHHCCEEEEEEECCCCCCCCCCCHHCCCEEEEEEECCEEEEECCCEE
LKDGLTDFNVYEVELKNKMVSKSKKVIALLDHTKIGYTSTTSFCSIDNLDVIVTDNKTPS
ECCCCCCCEEEEEEHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCEEEEEECCCCCH
NKIEEIRNAGIEVIVAE
HHHHHHHHCCEEEEEEC
>Mature Secondary Structure
MLSIARRNKILEILKEKHQITTQELEKELNVSGATVRNDLQELEKEGLLKRIHGGAVLPK
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCH
EQIFQNSYRNFHHRSKKNVQEKKAICRAASKFIDEGQTYLLDASSTVLYLVPYLREKHRI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEHHHCCCCEE
SIATNGLYTALEVKEICNINVIVLGGIAKPRSGSLEGLLGESILCKINADIMFTSAHGFT
EEEECCEEEHEEHHHHCCEEEEEEECCCCCCCCCCCHHCCCEEEEEEECCEEEEECCCEE
LKDGLTDFNVYEVELKNKMVSKSKKVIALLDHTKIGYTSTTSFCSIDNLDVIVTDNKTPS
ECCCCCCCEEEEEEHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCEEEEEECCCCCH
NKIEEIRNAGIEVIVAE
HHHHHHHHCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 7772602; 1661252 [H]