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The map label for this gene is ygcA [C]

Identifier: 220931148

GI number: 220931148

Start: 309898

End: 311259

Strand: Direct

Name: ygcA [C]

Synonym: Hore_03000

Alternate gene names: 220931148

Gene position: 309898-311259 (Clockwise)

Preceding gene: 220931147

Following gene: 220931150

Centisome position: 12.02

GC content: 39.72

Gene sequence:

>1362_bases
ATGGCAGCTAATGGAGATTTAATTGAATTGAAGCTGGACACTTTAGGTCATGGTGGGGAAGCAATTGGACGGTACCGGGG
ACTGGTTGTTTTTGTTCCTGAGGGTATACCAGGGGAGAAAGTAAGAGTCAAGATTAAAGAGAGAAAGAAAAATTATGCCC
GGGGTGAGATTAAAGAAATATTAACCCCGGCTCCGGAGCGGAAAGAGCCTGAGTGTGAAGTATTTGGCCTGTGTGGAGGA
TGCCATCTTCAACAGATGGATTACTCCTTACAACTGCTTCACAAACAGAAAATTGTTAAGGATACCCTGGAAAGAATAGG
GGGTTTTGAGGAAGTAAGGGTTAATGAAGTTATAGGAGCAGACCATCCCTGGATCTATCGGAATAAGGCCCAGTTTCCCC
TTGGAAGTGATAATGAAGGAAGGGTTATAACCGGTTTTTATCAAAAGGGCACCCATCAGGTTGTACCCCACCGTCAGTGT
GTTATCCAACATCCCTTAATTAATAGAATTGCCAGAAAAACCATTAGTATATTAAATAATTACGATTTAACGGTTTATGA
TGAAAAAACACATACCGGTTTATTGCGTCATCTGGTGGTCAGGGTCGGAATATGTACCAATCAGGCCCTTTTAATATTTG
TTACCAGGGATAAAAAATTTAAAGAATTACAGGAAATAGCCAGGAAGTTGATGACAGAGATTCCTGAGCTTAAAGGAGTC
CTGCAGAATATTAATCCCCGGCGTACCAATGTTATTATGGGAGATAAGACCCTCCTGATCAAAGGTAATGATTATTATAT
AGATTACATAGGCTCTATCAGATATGCTATTTCTCCACATTCTTTTTTCCAGGTAAATACTTTACAGACAGAAAGACTTT
ATAATACTGTTAGGAAATATGCCGGATTAAGTGGTCAGGAAACAGTAGTTGATGCCTATTGTGGAGCAGGTAGTATTGGT
ATTTACCTGGCCGGTGAAGCCAGGACTGTTTACGGGATAGAAGTGGTGGGGAGTGCTATTGAGGATGCGGAACGTAATGC
CGCCTTAAATGGTATAAATAATTGTATTTTTATTAAAGGTAAGGTAGAGGATAAATTACCGGAACTGGTTGATAAAAAAA
AGATAAAACCTGATGTTATTATATTTGATCCCCCGCGTAAAGGCCTTGATAAGGAAACTATGGCTACAGTTTTAGAGGTG
TTACCCCCAAAAATTGTTTATGTTTCCTGTAATCCAGCCACCCTGGCCCGGGATTTAAAAGAAATTAAAGCCTGCTATGA
TATAAATGAAGTCCAACCGGTAGATTTATTTCCACAGACATATCATGTGGAGTGTGTTGTAAAACTTGAGTCAAATGTTT
AA

Upstream 100 bases:

>100_bases
CGGGAAAGGGGTCTGGATATGAACGGTATCCGGACCTCCTTTTTTTTATTTGCTATAAGTGGTAAAATAAATATAATGAA
ATACAGGAGTGATTGCAATT

Downstream 100 bases:

>100_bases
AAAACAAAAAGTCCAGGGGTTACCCCCTGGACTTTAATTACTTTATTTATATTGAAAAAATGCTATTGATGGGCTTTTAT
AAAAGCCTCAATAGACCTAT

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MAANGDLIELKLDTLGHGGEAIGRYRGLVVFVPEGIPGEKVRVKIKERKKNYARGEIKEILTPAPERKEPECEVFGLCGG
CHLQQMDYSLQLLHKQKIVKDTLERIGGFEEVRVNEVIGADHPWIYRNKAQFPLGSDNEGRVITGFYQKGTHQVVPHRQC
VIQHPLINRIARKTISILNNYDLTVYDEKTHTGLLRHLVVRVGICTNQALLIFVTRDKKFKELQEIARKLMTEIPELKGV
LQNINPRRTNVIMGDKTLLIKGNDYYIDYIGSIRYAISPHSFFQVNTLQTERLYNTVRKYAGLSGQETVVDAYCGAGSIG
IYLAGEARTVYGIEVVGSAIEDAERNAALNGINNCIFIKGKVEDKLPELVDKKKIKPDVIIFDPPRKGLDKETMATVLEV
LPPKIVYVSCNPATLARDLKEIKACYDINEVQPVDLFPQTYHVECVVKLESNV

Sequences:

>Translated_453_residues
MAANGDLIELKLDTLGHGGEAIGRYRGLVVFVPEGIPGEKVRVKIKERKKNYARGEIKEILTPAPERKEPECEVFGLCGG
CHLQQMDYSLQLLHKQKIVKDTLERIGGFEEVRVNEVIGADHPWIYRNKAQFPLGSDNEGRVITGFYQKGTHQVVPHRQC
VIQHPLINRIARKTISILNNYDLTVYDEKTHTGLLRHLVVRVGICTNQALLIFVTRDKKFKELQEIARKLMTEIPELKGV
LQNINPRRTNVIMGDKTLLIKGNDYYIDYIGSIRYAISPHSFFQVNTLQTERLYNTVRKYAGLSGQETVVDAYCGAGSIG
IYLAGEARTVYGIEVVGSAIEDAERNAALNGINNCIFIKGKVEDKLPELVDKKKIKPDVIIFDPPRKGLDKETMATVLEV
LPPKIVYVSCNPATLARDLKEIKACYDINEVQPVDLFPQTYHVECVVKLESNV
>Mature_452_residues
AANGDLIELKLDTLGHGGEAIGRYRGLVVFVPEGIPGEKVRVKIKERKKNYARGEIKEILTPAPERKEPECEVFGLCGGC
HLQQMDYSLQLLHKQKIVKDTLERIGGFEEVRVNEVIGADHPWIYRNKAQFPLGSDNEGRVITGFYQKGTHQVVPHRQCV
IQHPLINRIARKTISILNNYDLTVYDEKTHTGLLRHLVVRVGICTNQALLIFVTRDKKFKELQEIARKLMTEIPELKGVL
QNINPRRTNVIMGDKTLLIKGNDYYIDYIGSIRYAISPHSFFQVNTLQTERLYNTVRKYAGLSGQETVVDAYCGAGSIGI
YLAGEARTVYGIEVVGSAIEDAERNAALNGINNCIFIKGKVEDKLPELVDKKKIKPDVIIFDPPRKGLDKETMATVLEVL
PPKIVYVSCNPATLARDLKEIKACYDINEVQPVDLFPQTYHVECVVKLESNV

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=350, Percent_Identity=29.7142857142857, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI51173878, Length=350, Percent_Identity=29.7142857142857, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI269784680, Length=205, Percent_Identity=33.1707317073171, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI269784676, Length=205, Percent_Identity=33.1707317073171, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI20149688, Length=205, Percent_Identity=33.1707317073171, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI269784678, Length=205, Percent_Identity=33.1707317073171, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1789148, Length=446, Percent_Identity=29.8206278026906, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787083, Length=329, Percent_Identity=26.1398176291793, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790403, Length=154, Percent_Identity=31.1688311688312, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71997438, Length=165, Percent_Identity=30.9090909090909, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322909, Length=417, Percent_Identity=24.4604316546763, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666579, Length=436, Percent_Identity=27.2935779816514, Blast_Score=131, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280
- InterPro:   IPR003402 [H]

Pfam domain/function: PF02475 Met_10; PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 50995; Mature: 50864

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS50926 TRAM ; PS01230 TRMA_1 ; PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAANGDLIELKLDTLGHGGEAIGRYRGLVVFVPEGIPGEKVRVKIKERKKNYARGEIKEI
CCCCCCEEEEEECCCCCCCHHHHHHCCEEEECCCCCCCCEEEEEEHHHCCCCCHHHHHHH
LTPAPERKEPECEVFGLCGGCHLQQMDYSLQLLHKQKIVKDTLERIGGFEEVRVNEVIGA
HCCCCCCCCCCCEEEEECCCCCHHHHCHHHHHHHHHHHHHHHHHHHCCHHHEEEHHHHCC
DHPWIYRNKAQFPLGSDNEGRVITGFYQKGTHQVVPHRQCVIQHPLINRIARKTISILNN
CCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCC
YDLTVYDEKTHTGLLRHLVVRVGICTNQALLIFVTRDKKFKELQEIARKLMTEIPELKGV
CCEEEEECCHHHHHHHHHHHHHEEECCCEEEEEEECCCHHHHHHHHHHHHHHHCHHHHHH
LQNINPRRTNVIMGDKTLLIKGNDYYIDYIGSIRYAISPHSFFQVNTLQTERLYNTVRKY
HHCCCCCCCEEEECCEEEEEECCCEEEEEECCEEEEECCCCEEEEECHHHHHHHHHHHHH
AGLSGQETVVDAYCGAGSIGIYLAGEARTVYGIEVVGSAIEDAERNAALNGINNCIFIKG
CCCCCCCEEEEHHCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEC
KVEDKLPELVDKKKIKPDVIIFDPPRKGLDKETMATVLEVLPPKIVYVSCNPATLARDLK
CCHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHH
EIKACYDINEVQPVDLFPQTYHVECVVKLESNV
HHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCC
>Mature Secondary Structure 
AANGDLIELKLDTLGHGGEAIGRYRGLVVFVPEGIPGEKVRVKIKERKKNYARGEIKEI
CCCCCEEEEEECCCCCCCHHHHHHCCEEEECCCCCCCCEEEEEEHHHCCCCCHHHHHHH
LTPAPERKEPECEVFGLCGGCHLQQMDYSLQLLHKQKIVKDTLERIGGFEEVRVNEVIGA
HCCCCCCCCCCCEEEEECCCCCHHHHCHHHHHHHHHHHHHHHHHHHCCHHHEEEHHHHCC
DHPWIYRNKAQFPLGSDNEGRVITGFYQKGTHQVVPHRQCVIQHPLINRIARKTISILNN
CCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCC
YDLTVYDEKTHTGLLRHLVVRVGICTNQALLIFVTRDKKFKELQEIARKLMTEIPELKGV
CCEEEEECCHHHHHHHHHHHHHEEECCCEEEEEEECCCHHHHHHHHHHHHHHHCHHHHHH
LQNINPRRTNVIMGDKTLLIKGNDYYIDYIGSIRYAISPHSFFQVNTLQTERLYNTVRKY
HHCCCCCCCEEEECCEEEEEECCCEEEEEECCEEEEECCCCEEEEECHHHHHHHHHHHHH
AGLSGQETVVDAYCGAGSIGIYLAGEARTVYGIEVVGSAIEDAERNAALNGINNCIFIKG
CCCCCCCEEEEHHCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEC
KVEDKLPELVDKKKIKPDVIIFDPPRKGLDKETMATVLEVLPPKIVYVSCNPATLARDLK
CCHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHH
EIKACYDINEVQPVDLFPQTYHVECVVKLESNV
HHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA