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The map label for this gene is nuoG [C]

Identifier: 220931146

GI number: 220931146

Start: 307388

End: 309100

Strand: Direct

Name: nuoG [C]

Synonym: Hore_02980

Alternate gene names: 220931146

Gene position: 307388-309100 (Clockwise)

Preceding gene: 220931145

Following gene: 220931147

Centisome position: 11.92

GC content: 42.15

Gene sequence:

>1713_bases
GTGGTAAAAATAAATATTGATGGGCTTGATCTGGAGGTCAGAGACGGAATTAGTATCCTGGAAGCTGCTCGCCAGGCCCA
TATTAAAATACCAACCCTATGCTATGAAGAAGGATTATCCGTATATGGTGGTTGTCGGTTATGTGTGGTTGAAATTGAAG
GAGAAGCCCTTTTAAAACCTGCCTGTGCTACAGAAGTTAATGATGGTATGGTAATCAAAACCCACTCCCCTAAAGTCAGA
GATGTTAGAAGAACTTTATTTGAATTAATAGTTGCCTCCCATAATATTGATTGTCAGTTAAATTGCCTAACCTGTAGTCG
GGCCGGAAGCTGTGAACTGAGGGAAATTGCCGAGGATATAGGTGTCAGTAATATCAGATTAGCTACCTATGACAAAGGTT
ACAGGGATGACCGGTCCAGTTATTCAATTGTGAGGGAGCCTAATAAATGTATAACCTGTGGTCGGTGTATCAGAAAATGT
GAAGAGGTCCAGGAGGTAGGTATTTTTACAACAGCCAATAGAGGACCGGCAACAGTGGTAACAACCTTCAAAGAAAAAGG
AATGGGGAATGTGGAGTGTACTAACTGTGGTCAGTGTATCCATGCCTGTCCGACAGGGGCCTTACATGAGGTGTATCACT
ATGAAAAAGTCTGGGAGGTGCTTCATGACAGGGATAAATATGTGGTAGTCCAGACGGCACCTGCTGTCAGGGTGGCCCTG
TCTGAGGCCTTTGGATTAAAACCGGGAACTATTTTTACAGGGCAGATGGTTGCTGGATTGAGGCGACTGGGCTTTGACCG
TGTCTTTGATACTAATTTTACAGCTGATTTAACCATCATGGAAGAGGGAACTGAATTGATAGAGCGGTTAAATAATAATG
GTGAGCTACCGATGTTTACTTCCTGTAGTCCGGGCTGGATTAAATATATAGAACACTTCTACCCTGAATTTATAGATAAT
TTGTCTACCTGTAAGTCACCACAGCAGATGTTTGGAGCGATTGCCAAATCTTATTATGCTGATAAAAGTAATATACCGAG
GGATAAAATAGTTGTAGTTTCGGTTATGCCCTGTACTGCCAAAAAATTTGAAGCCAGAAGACCGGAAATGGAGGGCGATG
TTGATTATGTTCTGACTACCAGGGAACTGGCCCGGATGATTAAAGAGGCAGGAATTGATATTACTAACCTTAATGCTGAA
GAGCATGATAAACTAATGGGAACATCATCGGGGGCTGCTGATATTTTCGGCGCAACCGGTGGGGTAATGGAAGCTGCCCT
GCGGACAGCCTATGAACTGGTAACCGGTGAAAAACTCGGTCAGCTGGACTTTAAGAATGTAAGGGGTGAAGCCGGAATTA
AGGAAGCAGAAGTTACCTTAAATGGAACTCAGTTGAAGGTAGCAGTAGCACATGGTCTGGGAAATGTCAGAAAACTGATG
GAGCTGATAAAATCAGGAAAAGAGTATCATTTTGTTGAGTTAATGGCCTGTCCCGGGGGATGTATTGGTGGTGGTGGTCA
ACCTATTCCCACCAGTGAGGATATAAGAAGAAAGCGAATTGAAGCTTTATATAAGATAGATAAAAATAAAAAATTAAGGA
AATCCCATGAAAATCCGTATATTAAAAAACTATATCAAGAATTCCTGGATAAACATGGAAGCCATAAAGCCCATGAACTG
CTCCATACCCATTATATAAACAGGGGTGTTTAA

Upstream 100 bases:

>100_bases
CATCTGGCTGCTAGATGTGGCCTCGGACAGACTTCATTAAATTTTGTAACTTCAGTTTTAAATAAATTTGAAGATGAATT
AATGGTCGGGAGGGATTAGA

Downstream 100 bases:

>100_bases
GATATGAATGAAGTTCCTCAGGCAACGATTGAAAGACTGGTGGTTTACTATCGATATTTAAAGAAAATGGCTGAACGCGA
CCTTGAAGATACCATTTCTT

Product: NADH dehydrogenase I subunit G

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MVKINIDGLDLEVRDGISILEAARQAHIKIPTLCYEEGLSVYGGCRLCVVEIEGEALLKPACATEVNDGMVIKTHSPKVR
DVRRTLFELIVASHNIDCQLNCLTCSRAGSCELREIAEDIGVSNIRLATYDKGYRDDRSSYSIVREPNKCITCGRCIRKC
EEVQEVGIFTTANRGPATVVTTFKEKGMGNVECTNCGQCIHACPTGALHEVYHYEKVWEVLHDRDKYVVVQTAPAVRVAL
SEAFGLKPGTIFTGQMVAGLRRLGFDRVFDTNFTADLTIMEEGTELIERLNNNGELPMFTSCSPGWIKYIEHFYPEFIDN
LSTCKSPQQMFGAIAKSYYADKSNIPRDKIVVVSVMPCTAKKFEARRPEMEGDVDYVLTTRELARMIKEAGIDITNLNAE
EHDKLMGTSSGAADIFGATGGVMEAALRTAYELVTGEKLGQLDFKNVRGEAGIKEAEVTLNGTQLKVAVAHGLGNVRKLM
ELIKSGKEYHFVELMACPGGCIGGGGQPIPTSEDIRRKRIEALYKIDKNKKLRKSHENPYIKKLYQEFLDKHGSHKAHEL
LHTHYINRGV

Sequences:

>Translated_570_residues
MVKINIDGLDLEVRDGISILEAARQAHIKIPTLCYEEGLSVYGGCRLCVVEIEGEALLKPACATEVNDGMVIKTHSPKVR
DVRRTLFELIVASHNIDCQLNCLTCSRAGSCELREIAEDIGVSNIRLATYDKGYRDDRSSYSIVREPNKCITCGRCIRKC
EEVQEVGIFTTANRGPATVVTTFKEKGMGNVECTNCGQCIHACPTGALHEVYHYEKVWEVLHDRDKYVVVQTAPAVRVAL
SEAFGLKPGTIFTGQMVAGLRRLGFDRVFDTNFTADLTIMEEGTELIERLNNNGELPMFTSCSPGWIKYIEHFYPEFIDN
LSTCKSPQQMFGAIAKSYYADKSNIPRDKIVVVSVMPCTAKKFEARRPEMEGDVDYVLTTRELARMIKEAGIDITNLNAE
EHDKLMGTSSGAADIFGATGGVMEAALRTAYELVTGEKLGQLDFKNVRGEAGIKEAEVTLNGTQLKVAVAHGLGNVRKLM
ELIKSGKEYHFVELMACPGGCIGGGGQPIPTSEDIRRKRIEALYKIDKNKKLRKSHENPYIKKLYQEFLDKHGSHKAHEL
LHTHYINRGV
>Mature_570_residues
MVKINIDGLDLEVRDGISILEAARQAHIKIPTLCYEEGLSVYGGCRLCVVEIEGEALLKPACATEVNDGMVIKTHSPKVR
DVRRTLFELIVASHNIDCQLNCLTCSRAGSCELREIAEDIGVSNIRLATYDKGYRDDRSSYSIVREPNKCITCGRCIRKC
EEVQEVGIFTTANRGPATVVTTFKEKGMGNVECTNCGQCIHACPTGALHEVYHYEKVWEVLHDRDKYVVVQTAPAVRVAL
SEAFGLKPGTIFTGQMVAGLRRLGFDRVFDTNFTADLTIMEEGTELIERLNNNGELPMFTSCSPGWIKYIEHFYPEFIDN
LSTCKSPQQMFGAIAKSYYADKSNIPRDKIVVVSVMPCTAKKFEARRPEMEGDVDYVLTTRELARMIKEAGIDITNLNAE
EHDKLMGTSSGAADIFGATGGVMEAALRTAYELVTGEKLGQLDFKNVRGEAGIKEAEVTLNGTQLKVAVAHGLGNVRKLM
ELIKSGKEYHFVELMACPGGCIGGGGQPIPTSEDIRRKRIEALYKIDKNKKLRKSHENPYIKKLYQEFLDKHGSHKAHEL
LHTHYINRGV

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=399, Percent_Identity=31.077694235589, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI6912524, Length=364, Percent_Identity=30.2197802197802, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI134284357, Length=364, Percent_Identity=30.2197802197802, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI84452151, Length=364, Percent_Identity=30.2197802197802, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI14165461, Length=404, Percent_Identity=29.2079207920792, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI33519475, Length=221, Percent_Identity=32.579185520362, Blast_Score=113, Evalue=4e-25,
Organism=Escherichia coli, GI145693161, Length=260, Percent_Identity=25, Blast_Score=89, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71995015, Length=441, Percent_Identity=30.3854875283447, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI32566231, Length=249, Percent_Identity=31.3253012048193, Blast_Score=115, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17565758, Length=223, Percent_Identity=32.2869955156951, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193209088, Length=249, Percent_Identity=31.3253012048193, Blast_Score=114, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324089, Length=386, Percent_Identity=24.3523316062176, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI116007470, Length=362, Percent_Identity=32.5966850828729, Blast_Score=175, Evalue=9e-44,
Organism=Drosophila melanogaster, GI116007466, Length=362, Percent_Identity=32.5966850828729, Blast_Score=175, Evalue=9e-44,
Organism=Drosophila melanogaster, GI116007464, Length=362, Percent_Identity=32.5966850828729, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI116007468, Length=362, Percent_Identity=32.5966850828729, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI116007462, Length=286, Percent_Identity=34.2657342657343, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24640559, Length=225, Percent_Identity=32, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24640557, Length=225, Percent_Identity=32, Blast_Score=112, Evalue=8e-25,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 63328; Mature: 63328

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00028 ZINC_FINGER_C2H2_1 ; PS00641 COMPLEX1_75K_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKINIDGLDLEVRDGISILEAARQAHIKIPTLCYEEGLSVYGGCRLCVVEIEGEALLKP
CEEEEECCCEEEHHCCHHHHHHHHHCCCCCCHHHHHCCCCEECCCEEEEEEECCCHHCCC
ACATEVNDGMVIKTHSPKVRDVRRTLFELIVASHNIDCQLNCLTCSRAGSCELREIAEDI
HHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHC
GVSNIRLATYDKGYRDDRSSYSIVREPNKCITCGRCIRKCEEVQEVGIFTTANRGPATVV
CCCCEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEE
TTFKEKGMGNVECTNCGQCIHACPTGALHEVYHYEKVWEVLHDRDKYVVVQTAPAVRVAL
EEHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
SEAFGLKPGTIFTGQMVAGLRRLGFDRVFDTNFTADLTIMEEGTELIERLNNNGELPMFT
HHHHCCCCCCEECHHHHHHHHHHCCHHEECCCCCEEEEEHHHHHHHHHHHCCCCCCCEEE
SCSPGWIKYIEHFYPEFIDNLSTCKSPQQMFGAIAKSYYADKSNIPRDKIVVVSVMPCTA
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCH
KKFEARRPEMEGDVDYVLTTRELARMIKEAGIDITNLNAEEHDKLMGTSSGAADIFGATG
HHHHCCCCCCCCCCCEEEEHHHHHHHHHHCCCCEEECCHHHHHHHHCCCCCCCHHHCCCC
GVMEAALRTAYELVTGEKLGQLDFKNVRGEAGIKEAEVTLNGTQLKVAVAHGLGNVRKLM
HHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEEEEECCCEEEEEHHHCCHHHHHHH
ELIKSGKEYHFVELMACPGGCIGGGGQPIPTSEDIRRKRIEALYKIDKNKKLRKSHENPY
HHHHCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCHH
IKKLYQEFLDKHGSHKAHELLHTHYINRGV
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVKINIDGLDLEVRDGISILEAARQAHIKIPTLCYEEGLSVYGGCRLCVVEIEGEALLKP
CEEEEECCCEEEHHCCHHHHHHHHHCCCCCCHHHHHCCCCEECCCEEEEEEECCCHHCCC
ACATEVNDGMVIKTHSPKVRDVRRTLFELIVASHNIDCQLNCLTCSRAGSCELREIAEDI
HHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHC
GVSNIRLATYDKGYRDDRSSYSIVREPNKCITCGRCIRKCEEVQEVGIFTTANRGPATVV
CCCCEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEE
TTFKEKGMGNVECTNCGQCIHACPTGALHEVYHYEKVWEVLHDRDKYVVVQTAPAVRVAL
EEHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
SEAFGLKPGTIFTGQMVAGLRRLGFDRVFDTNFTADLTIMEEGTELIERLNNNGELPMFT
HHHHCCCCCCEECHHHHHHHHHHCCHHEECCCCCEEEEEHHHHHHHHHHHCCCCCCCEEE
SCSPGWIKYIEHFYPEFIDNLSTCKSPQQMFGAIAKSYYADKSNIPRDKIVVVSVMPCTA
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCH
KKFEARRPEMEGDVDYVLTTRELARMIKEAGIDITNLNAEEHDKLMGTSSGAADIFGATG
HHHHCCCCCCCCCCCEEEEHHHHHHHHHHCCCCEEECCHHHHHHHHCCCCCCCHHHCCCC
GVMEAALRTAYELVTGEKLGQLDFKNVRGEAGIKEAEVTLNGTQLKVAVAHGLGNVRKLM
HHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEEEEECCCEEEEEHHHCCHHHHHHH
ELIKSGKEYHFVELMACPGGCIGGGGQPIPTSEDIRRKRIEALYKIDKNKKLRKSHENPY
HHHHCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCHH
IKKLYQEFLDKHGSHKAHELLHTHYINRGV
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]