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The map label for this gene is feoB2 [H]

Identifier: 220931118

GI number: 220931118

Start: 274273

End: 275682

Strand: Reverse

Name: feoB2 [H]

Synonym: Hore_02700

Alternate gene names: 220931118

Gene position: 275682-274273 (Counterclockwise)

Preceding gene: 220931119

Following gene: 220931116

Centisome position: 10.69

GC content: 40.14

Gene sequence:

>1410_bases
ATGGAGTTAGTTTCAAGCAGTGTTAAAATAAAAAATATTTTCAAAGAGGTTGATAATAAATTTACTTCAGAACAAAAAAA
ATTACTCCGTGACCAGATAGTTAAAGATATTTATTCTTTTGCAGAAACAATTGCCAGAAAAACTGTTAAAGTTAATAATA
AAAAGAAAACAGACTTGGGTGAGAAAATTGATGATATTCTAACCTCCAAATGGTTGGGCTTTCCCATTATGCTTTTAATG
CTTGGTGGAGTTTTCTGGTTAACTATCGCTGGAGCCAATGTTCCTTCTGCTTTACTGGCTAAAGGACTATTCTGGATAGA
AGGCCGATTGTCAGATTTCTTTATATGGATAAAGGCCCCGGAATGGCTCCATGGTATTCTGGTCCTGGGAGTTTACCGGA
CTATGGCATGGGTTGTCTCAGTAATGCTTCCCCCTATGGCTATCTTCTTTCCCCTGTTCACCTTAATGGAAGACCTGGGC
TACTTACCAAGGGTTGCTTTTAACCTGGATAATTTTTTCAAGAAAGCAGGTGCCCACGGGAAACAGTCACTAACAATGAG
TATGGGATTTGGTTGTAATGCTGCCGGGGTTATTTCAGCCCGTATTATTGACTCCCCAAGGGAAAAGTTAATTGCAATAA
TAACCAATAACTTTGTCCCCTGTAATGGCCGTTTCCCAACATTAATCATACTCGCTACCATTTTTATGGGAACTGTTGTA
AGTAATACTTATAGTTCCTTTATAGCTGCCGCAACTGTAGTAGGGTTGGTACTGTTTGGCATTATTATAACATTAGTGGT
TTCCTGGGGCCTATCCAAAACTGTTCTCAAGGGTGTTCCATCATCCTTTACCCTGGAACTCCCCCCATACCGAAAGCCTC
AAATCGGGAGGGTCCTGGTCAGATCTTTTCTGGATAGAACTCTATTTGTACTGGGTAGGGCGGTTATTGTTGCTGCCCCC
GCCGGGGCTATAGTCTGGATTTTTGCCAATGTAGGACTTAATGGAGTTAGTTTAATCGATCATGTAGCAAACCTTTTGGA
TCCCTTTGCAGTTTTAATAGGACTTGATGGTTTTATTCTCCTGGCCTTTATCCTTGGATTACCGGCCAATGAAATAGTAA
TACCTATCCTGGTGATGAGTTATCTTTCAGCAGGAACCATGCTAGAACCTGAAAGTGCCAATGCTTTACGAGATATCCTT
GTCAACAATGGCTGGACCTGGGTTACAGCTCTGGCAACCATGCTTTTTTCCCTGCTACATTTTCCCTGTGGAACAACCCT
GCTCACAATCCGAAAAGAAACTCAGAGTATAAAATGGACCATCTTTACATTTATTCTAACAACATCTATTGCCATTGTAG
TTACTTTTGTAGTAGTCCAATTAATAGAATTATTTGGACTAATTTTGTAA

Upstream 100 bases:

>100_bases
TTAATAGAAGGAGACAAAACAATAATGGAGTCAATTGAAAAGTATGTTTTAAGGTCAAAACCTGAATTTAATTTATCAGC
GAAACGGGAGGTTTAAACTG

Downstream 100 bases:

>100_bases
ATATTTTATAAAAATTGTTTAGATATCATACTGGCTAAATTGGGAATTCTCTTTATTTTCCCTTTGAAACCTGGTTAACA
TTTTTTGTATCCCGGGGTTT

Product: ferrous iron transport protein FeoB

Products: Fe (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MELVSSSVKIKNIFKEVDNKFTSEQKKLLRDQIVKDIYSFAETIARKTVKVNNKKKTDLGEKIDDILTSKWLGFPIMLLM
LGGVFWLTIAGANVPSALLAKGLFWIEGRLSDFFIWIKAPEWLHGILVLGVYRTMAWVVSVMLPPMAIFFPLFTLMEDLG
YLPRVAFNLDNFFKKAGAHGKQSLTMSMGFGCNAAGVISARIIDSPREKLIAIITNNFVPCNGRFPTLIILATIFMGTVV
SNTYSSFIAAATVVGLVLFGIIITLVVSWGLSKTVLKGVPSSFTLELPPYRKPQIGRVLVRSFLDRTLFVLGRAVIVAAP
AGAIVWIFANVGLNGVSLIDHVANLLDPFAVLIGLDGFILLAFILGLPANEIVIPILVMSYLSAGTMLEPESANALRDIL
VNNGWTWVTALATMLFSLLHFPCGTTLLTIRKETQSIKWTIFTFILTTSIAIVVTFVVVQLIELFGLIL

Sequences:

>Translated_469_residues
MELVSSSVKIKNIFKEVDNKFTSEQKKLLRDQIVKDIYSFAETIARKTVKVNNKKKTDLGEKIDDILTSKWLGFPIMLLM
LGGVFWLTIAGANVPSALLAKGLFWIEGRLSDFFIWIKAPEWLHGILVLGVYRTMAWVVSVMLPPMAIFFPLFTLMEDLG
YLPRVAFNLDNFFKKAGAHGKQSLTMSMGFGCNAAGVISARIIDSPREKLIAIITNNFVPCNGRFPTLIILATIFMGTVV
SNTYSSFIAAATVVGLVLFGIIITLVVSWGLSKTVLKGVPSSFTLELPPYRKPQIGRVLVRSFLDRTLFVLGRAVIVAAP
AGAIVWIFANVGLNGVSLIDHVANLLDPFAVLIGLDGFILLAFILGLPANEIVIPILVMSYLSAGTMLEPESANALRDIL
VNNGWTWVTALATMLFSLLHFPCGTTLLTIRKETQSIKWTIFTFILTTSIAIVVTFVVVQLIELFGLIL
>Mature_469_residues
MELVSSSVKIKNIFKEVDNKFTSEQKKLLRDQIVKDIYSFAETIARKTVKVNNKKKTDLGEKIDDILTSKWLGFPIMLLM
LGGVFWLTIAGANVPSALLAKGLFWIEGRLSDFFIWIKAPEWLHGILVLGVYRTMAWVVSVMLPPMAIFFPLFTLMEDLG
YLPRVAFNLDNFFKKAGAHGKQSLTMSMGFGCNAAGVISARIIDSPREKLIAIITNNFVPCNGRFPTLIILATIFMGTVV
SNTYSSFIAAATVVGLVLFGIIITLVVSWGLSKTVLKGVPSSFTLELPPYRKPQIGRVLVRSFLDRTLFVLGRAVIVAAP
AGAIVWIFANVGLNGVSLIDHVANLLDPFAVLIGLDGFILLAFILGLPANEIVIPILVMSYLSAGTMLEPESANALRDIL
VNNGWTWVTALATMLFSLLHFPCGTTLLTIRKETQSIKWTIFTFILTTSIAIVVTFVVVQLIELFGLIL

Specific function: Not involved in Fe(2+) uptake but is involved in manganese uptake. Could be GTP-driven [H]

COG id: COG0370

COG function: function code P; Fe2+ transport system protein B

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789813, Length=267, Percent_Identity=28.8389513108614, Blast_Score=105, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011640
- InterPro:   IPR011619
- InterPro:   IPR011642
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF07664 FeoB_C; PF02421 FeoB_N; PF07670 Gate; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51593; Mature: 51593

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVSSSVKIKNIFKEVDNKFTSEQKKLLRDQIVKDIYSFAETIARKTVKVNNKKKTDLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
EKIDDILTSKWLGFPIMLLMLGGVFWLTIAGANVPSALLAKGLFWIEGRLSDFFIWIKAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHEECCCCEEEEEEECH
EWLHGILVLGVYRTMAWVVSVMLPPMAIFFPLFTLMEDLGYLPRVAFNLDNFFKKAGAHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
KQSLTMSMGFGCNAAGVISARIIDSPREKLIAIITNNFVPCNGRFPTLIILATIFMGTVV
CCCEEEEECCCCCCHHHHHHHHHCCHHHHEEEHEECCEEECCCCCHHHHHHHHHHHHHHH
SNTYSSFIAAATVVGLVLFGIIITLVVSWGLSKTVLKGVPSSFTLELPPYRKPQIGRVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCCCCHHHHHHH
RSFLDRTLFVLGRAVIVAAPAGAIVWIFANVGLNGVSLIDHVANLLDPFAVLIGLDGFIL
HHHHHHHHHHHHHHHHEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
LAFILGLPANEIVIPILVMSYLSAGTMLEPESANALRDILVNNGWTWVTALATMLFSLLH
HHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
FPCGTTLLTIRKETQSIKWTIFTFILTTSIAIVVTFVVVQLIELFGLIL
CCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELVSSSVKIKNIFKEVDNKFTSEQKKLLRDQIVKDIYSFAETIARKTVKVNNKKKTDLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
EKIDDILTSKWLGFPIMLLMLGGVFWLTIAGANVPSALLAKGLFWIEGRLSDFFIWIKAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHEECCCCEEEEEEECH
EWLHGILVLGVYRTMAWVVSVMLPPMAIFFPLFTLMEDLGYLPRVAFNLDNFFKKAGAHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
KQSLTMSMGFGCNAAGVISARIIDSPREKLIAIITNNFVPCNGRFPTLIILATIFMGTVV
CCCEEEEECCCCCCHHHHHHHHHCCHHHHEEEHEECCEEECCCCCHHHHHHHHHHHHHHH
SNTYSSFIAAATVVGLVLFGIIITLVVSWGLSKTVLKGVPSSFTLELPPYRKPQIGRVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCCCCHHHHHHH
RSFLDRTLFVLGRAVIVAAPAGAIVWIFANVGLNGVSLIDHVANLLDPFAVLIGLDGFIL
HHHHHHHHHHHHHHHHEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
LAFILGLPANEIVIPILVMSYLSAGTMLEPESANALRDILVNNGWTWVTALATMLFSLLH
HHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
FPCGTTLLTIRKETQSIKWTIFTFILTTSIAIVVTFVVVQLIELFGLIL
CCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fe (II) [Periplasm] [C]

Specific reaction: Fe (II) [Periplasm] = Fe (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]