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The map label for this gene is alr

Identifier: 220931017

GI number: 220931017

Start: 173717

End: 174856

Strand: Direct

Name: alr

Synonym: Hore_01680

Alternate gene names: 220931017

Gene position: 173717-174856 (Clockwise)

Preceding gene: 220931016

Following gene: 220931018

Centisome position: 6.74

GC content: 42.89

Gene sequence:

>1140_bases
GTGAATAAAAGGATTACACGTCCGACCTGGGCAGAAATCGACCTATCCTGTCTCCAGTTTAATTTTAATCAAGTAAAAGA
AATATTGGGAAGTAATGTTAAAATAATGTCAGTTGTTAAGGCCGATGCCTACGGCCATGGTGTTATTCCTGTTGCTAAAA
CCCTGGTTGAGGCTGGAACTCAACGTCTGGCGGTAGCTATACCTGAGGAGGGGGTTGAACTCAGGGAAGCAGGTCTTTCT
GTCCCCATTCAGGTATTGGGAGAGGTATTACCCTCCCAGTATGAACTGTTATTTAAATATGATTTAATTCCCACTGTTGG
CCGGGAGGAAACAGCCCTGAGCCTGAATCGCCTGGCCGCCAAATACAATGTGGTTAAGAAAGTCCATATCAAAGTAGATA
CCGGCATGGGACGTATCGGGGTCAGGCCCCGGGAAGCGGTTGGTTTTGTTAAAAAAGTGAATTCATTAAGTAATATAAAA
ATTGAGGGGTTAATGACTCATTTTGCCAGTGCTGATGAACGGGATAAGAGCTATACCTATGAGCAATGGGATAAGTTTAA
ACAGGTCCTTGACGGGTTAAACAAATTGAGAATTGATATTCCCATAAAACACAGCAGTAATAGTGCTGCCATAATAGATT
TTAAGAAATTTGGTCTGGATATGGTGAGACCCGGTATTATGTTATATGGTTTGAAACCCTCCCGGGACCTTATTAACAAC
ATAGATTTAAAACCTGTTTTAACCTGGAAGACCCGGATAGTTTATCTTAAAGAAGTGCCCCCCGGTACGGGGATAAGTTA
TGGAACTACTTATGTTACCAACCGGAAAAGCAAGATTGCTACTCTGCCGGTAGGTTATGCTGATGGTTACCCCAGAATTT
TATCAAACCAGGGTCAGGTTTTAGTACGGGGCAGGAAGGCCCCAATCAGGGGCAGGGTCTGCATGGATCAGATAATGATA
GATGTTACTGAAATACCTGACGTCAGGGTCGGGGATGAGGTTGTGTTGATTGGGGAACAGGGTACTCAAAAAATATCGGC
TACAGATATAGCTGAAAAGGCCGATACAATAAATTATGAAATTGTTTGTGGGATTAGCCAGAGGGTCCCCAGAGAATATA
AAAATAAAATTGGGGGGTAA

Upstream 100 bases:

>100_bases
TCCCTTACTGCAGGGACAATAATTGAGTTTATAGCCGGAGCTATAATGGATTTGACAACTTCGGTGATAAATTAGAAAAT
ATATAATAAAGGTGATATCT

Downstream 100 bases:

>100_bases
AGTATGATAACAAAACAGGTATATGTCAATATAAAAACAGGTCTCCATGCCAGGCCAGCATCTTATTTTGTGGATGTGGC
CAGCAAGTTTGTTTCAGATA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNKRITRPTWAEIDLSCLQFNFNQVKEILGSNVKIMSVVKADAYGHGVIPVAKTLVEAGTQRLAVAIPEEGVELREAGLS
VPIQVLGEVLPSQYELLFKYDLIPTVGREETALSLNRLAAKYNVVKKVHIKVDTGMGRIGVRPREAVGFVKKVNSLSNIK
IEGLMTHFASADERDKSYTYEQWDKFKQVLDGLNKLRIDIPIKHSSNSAAIIDFKKFGLDMVRPGIMLYGLKPSRDLINN
IDLKPVLTWKTRIVYLKEVPPGTGISYGTTYVTNRKSKIATLPVGYADGYPRILSNQGQVLVRGRKAPIRGRVCMDQIMI
DVTEIPDVRVGDEVVLIGEQGTQKISATDIAEKADTINYEIVCGISQRVPREYKNKIGG

Sequences:

>Translated_379_residues
MNKRITRPTWAEIDLSCLQFNFNQVKEILGSNVKIMSVVKADAYGHGVIPVAKTLVEAGTQRLAVAIPEEGVELREAGLS
VPIQVLGEVLPSQYELLFKYDLIPTVGREETALSLNRLAAKYNVVKKVHIKVDTGMGRIGVRPREAVGFVKKVNSLSNIK
IEGLMTHFASADERDKSYTYEQWDKFKQVLDGLNKLRIDIPIKHSSNSAAIIDFKKFGLDMVRPGIMLYGLKPSRDLINN
IDLKPVLTWKTRIVYLKEVPPGTGISYGTTYVTNRKSKIATLPVGYADGYPRILSNQGQVLVRGRKAPIRGRVCMDQIMI
DVTEIPDVRVGDEVVLIGEQGTQKISATDIAEKADTINYEIVCGISQRVPREYKNKIGG
>Mature_379_residues
MNKRITRPTWAEIDLSCLQFNFNQVKEILGSNVKIMSVVKADAYGHGVIPVAKTLVEAGTQRLAVAIPEEGVELREAGLS
VPIQVLGEVLPSQYELLFKYDLIPTVGREETALSLNRLAAKYNVVKKVHIKVDTGMGRIGVRPREAVGFVKKVNSLSNIK
IEGLMTHFASADERDKSYTYEQWDKFKQVLDGLNKLRIDIPIKHSSNSAAIIDFKKFGLDMVRPGIMLYGLKPSRDLINN
IDLKPVLTWKTRIVYLKEVPPGTGISYGTTYVTNRKSKIATLPVGYADGYPRILSNQGQVLVRGRKAPIRGRVCMDQIMI
DVTEIPDVRVGDEVVLIGEQGTQKISATDIAEKADTINYEIVCGISQRVPREYKNKIGG

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1790487, Length=371, Percent_Identity=31.8059299191375, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1787439, Length=372, Percent_Identity=32.7956989247312, Blast_Score=177, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_HALOH (B8D0W1)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002507925.1
- ProteinModelPortal:   B8D0W1
- SMR:   B8D0W1
- GeneID:   7313296
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_01680
- HOGENOM:   HBG712172
- OMA:   SVELWGD
- ProtClustDB:   CLSK2806173
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 42139; Mature: 42139

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 40-40 ACT_SITE 267-267

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRITRPTWAEIDLSCLQFNFNQVKEILGSNVKIMSVVKADAYGHGVIPVAKTLVEAGT
CCCCCCCCCCHHCCHHHEECCHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHCCC
QRLAVAIPEEGVELREAGLSVPIQVLGEVLPSQYELLFKYDLIPTVGREETALSLNRLAA
CEEEEECCCCCHHHHHCCCCCCHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHH
KYNVVKKVHIKVDTGMGRIGVRPREAVGFVKKVNSLSNIKIEGLMTHFASADERDKSYTY
HHEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCCCCH
EQWDKFKQVLDGLNKLRIDIPIKHSSNSAAIIDFKKFGLDMVRPGIMLYGLKPSRDLINN
HHHHHHHHHHCCHHEEEEEEEEEECCCCEEEEEHHHHCHHHHCCCEEEEECCCCHHHHHC
IDLKPVLTWKTRIVYLKEVPPGTGISYGTTYVTNRKSKIATLPVGYADGYPRILSNQGQV
CCCCEEEEEEEEEEEEEECCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHCCCCCE
LVRGRKAPIRGRVCMDQIMIDVTEIPDVRVGDEVVLIGEQGTQKISATDIAEKADTINYE
EEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEECHHHHHHHHCCCCEE
IVCGISQRVPREYKNKIGG
EEECCHHHCCHHHHHHCCC
>Mature Secondary Structure
MNKRITRPTWAEIDLSCLQFNFNQVKEILGSNVKIMSVVKADAYGHGVIPVAKTLVEAGT
CCCCCCCCCCHHCCHHHEECCHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHCCC
QRLAVAIPEEGVELREAGLSVPIQVLGEVLPSQYELLFKYDLIPTVGREETALSLNRLAA
CEEEEECCCCCHHHHHCCCCCCHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHH
KYNVVKKVHIKVDTGMGRIGVRPREAVGFVKKVNSLSNIKIEGLMTHFASADERDKSYTY
HHEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCCCCH
EQWDKFKQVLDGLNKLRIDIPIKHSSNSAAIIDFKKFGLDMVRPGIMLYGLKPSRDLINN
HHHHHHHHHHCCHHEEEEEEEEEECCCCEEEEEHHHHCHHHHCCCEEEEECCCCHHHHHC
IDLKPVLTWKTRIVYLKEVPPGTGISYGTTYVTNRKSKIATLPVGYADGYPRILSNQGQV
CCCCEEEEEEEEEEEEEECCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHCCCCCE
LVRGRKAPIRGRVCMDQIMIDVTEIPDVRVGDEVVLIGEQGTQKISATDIAEKADTINYE
EEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEECHHHHHHHHCCCCEE
IVCGISQRVPREYKNKIGG
EEECCHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA