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The map label for this gene is xylR [H]

Identifier: 220930925

GI number: 220930925

Start: 88980

End: 90116

Strand: Direct

Name: xylR [H]

Synonym: Hore_00770

Alternate gene names: 220930925

Gene position: 88980-90116 (Clockwise)

Preceding gene: 220930924

Following gene: 220930926

Centisome position: 3.45

GC content: 37.64

Gene sequence:

>1137_bases
ATGCAAAGAGGTAATATGAAATTAATGAAAAAGATAAACAGGGCCTTAATTATTCAGACCTTAAGTCAGCAGGGCCCCCT
TTCGCGAGCAGATTTAACTAAAATTACTGATTTAAGTCCGACAACAATATCATCAATTACAGAAGAACTAATTCAGGAAG
GCCTTATAGTGGAAGTAGGAGAAGGAGAATCAAAAGGGGGACGTCGTCCTATCCTCCTTGATATAAATCCAGAAGATTTT
TATATTTTGAGTGTTAATATAGCTGTTGATGTTATGTATGTTTATTTATTTAATCTTAAATTCCAGGTTATAAATAGTGT
TCATGACTTAATAAAAAAACCGGTCAGCCCAAATCTGGATTCGCAGCTTAAAGAGTTGGTCCAGAAAGTAGTTGAAAATA
GCAATATAGGTAAAAAAAATGTTGTGGGCATGGGTATTGGGGCCACAGGGATAATTAATAAAGAAAAAGGTTTAATAACC
TATTCAGCCAGTCTGGGAATAAGTGACTATCCCCTGCTTGATAAAGTAAAGCGAGAATATGATTTCCCCATCTTGCTCGA
AAATGATACCAATCTGGCTGCCCTGGGAGAGAAAAAATTTGGTTGTGGCCGTCAATTAACTAACTTTTTTTACATAATGA
TAGGTTCTGCTATTGGTGGTGGCATAATTATTGATAACGAGATTTACCGGGGCAAGTTTGGAGGGGCCGGTGAATTTGGC
CACATTACTGTAGAGAAAGATGGCCCCCTTTGTGAATGTGGTAATCAAGGGTGCTTAAATGCAGTTTTGACTCCTTATAT
AACTGTAAGGAGCAGGGAAGAGTTTCGTAAATCCTTTCAGGAGATTATTAAAGACGACAACTTTGATTCTTGTCGGTACC
ATGAGTTTTGTGAGTATCTGGCTATGGCTATAACCAATTATACTAAACTTTTTGATCCTGAAGCCATTGTACTGGGGGGA
GAGATTGCCAGAATTGCCCCTGAGAGATTTTATATTGACCTGGAGAAATATATAAAGAGGATGTCCCTTAAGGGTATGAA
TAGTAAGATCCCGGTTTTACCTTCCAGTATTCGGACAAATGCAGTAGTTCTTGGTGGGGCCTGTCTCTGTTTTGATAATC
TTTATAATAATGTTTAA

Upstream 100 bases:

>100_bases
TCATCTTGAAAAAGTTATTATTTTTTTAAAGTAATTATTTTTTACATACTTATTACGGACGACAAAAAAAGTTTCCGGTG
ATAAAATCGGGGTGAGATTT

Downstream 100 bases:

>100_bases
GGTACTATTAACCGGGTACTTCAATTTCCTTTTGGAAGGTTGGTCCAGTTCCATAATAAAATGGCTTATGGTTGTAATAG
ACTTTAAAGGGGGTGAAGAG

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MQRGNMKLMKKINRALIIQTLSQQGPLSRADLTKITDLSPTTISSITEELIQEGLIVEVGEGESKGGRRPILLDINPEDF
YILSVNIAVDVMYVYLFNLKFQVINSVHDLIKKPVSPNLDSQLKELVQKVVENSNIGKKNVVGMGIGATGIINKEKGLIT
YSASLGISDYPLLDKVKREYDFPILLENDTNLAALGEKKFGCGRQLTNFFYIMIGSAIGGGIIIDNEIYRGKFGGAGEFG
HITVEKDGPLCECGNQGCLNAVLTPYITVRSREEFRKSFQEIIKDDNFDSCRYHEFCEYLAMAITNYTKLFDPEAIVLGG
EIARIAPERFYIDLEKYIKRMSLKGMNSKIPVLPSSIRTNAVVLGGACLCFDNLYNNV

Sequences:

>Translated_378_residues
MQRGNMKLMKKINRALIIQTLSQQGPLSRADLTKITDLSPTTISSITEELIQEGLIVEVGEGESKGGRRPILLDINPEDF
YILSVNIAVDVMYVYLFNLKFQVINSVHDLIKKPVSPNLDSQLKELVQKVVENSNIGKKNVVGMGIGATGIINKEKGLIT
YSASLGISDYPLLDKVKREYDFPILLENDTNLAALGEKKFGCGRQLTNFFYIMIGSAIGGGIIIDNEIYRGKFGGAGEFG
HITVEKDGPLCECGNQGCLNAVLTPYITVRSREEFRKSFQEIIKDDNFDSCRYHEFCEYLAMAITNYTKLFDPEAIVLGG
EIARIAPERFYIDLEKYIKRMSLKGMNSKIPVLPSSIRTNAVVLGGACLCFDNLYNNV
>Mature_378_residues
MQRGNMKLMKKINRALIIQTLSQQGPLSRADLTKITDLSPTTISSITEELIQEGLIVEVGEGESKGGRRPILLDINPEDF
YILSVNIAVDVMYVYLFNLKFQVINSVHDLIKKPVSPNLDSQLKELVQKVVENSNIGKKNVVGMGIGATGIINKEKGLIT
YSASLGISDYPLLDKVKREYDFPILLENDTNLAALGEKKFGCGRQLTNFFYIMIGSAIGGGIIIDNEIYRGKFGGAGEFG
HITVEKDGPLCECGNQGCLNAVLTPYITVRSREEFRKSFQEIIKDDNFDSCRYHEFCEYLAMAITNYTKLFDPEAIVLGG
EIARIAPERFYIDLEKYIKRMSLKGMNSKIPVLPSSIRTNAVVLGGACLCFDNLYNNV

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=187, Percent_Identity=30.4812834224599, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI298566315, Length=187, Percent_Identity=30.4812834224599, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI4885285, Length=187, Percent_Identity=30.4812834224599, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI190014632, Length=187, Percent_Identity=30.4812834224599, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI1786891, Length=381, Percent_Identity=24.9343832020997, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1787878, Length=394, Percent_Identity=23.6040609137056, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082127, Length=267, Percent_Identity=22.8464419475655, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081733, Length=250, Percent_Identity=24.8, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790522, Length=239, Percent_Identity=25.5230125523013, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787363, Length=222, Percent_Identity=27.4774774774775, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 42037; Mature: 42037

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRGNMKLMKKINRALIIQTLSQQGPLSRADLTKITDLSPTTISSITEELIQEGLIVEVG
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEC
EGESKGGRRPILLDINPEDFYILSVNIAVDVMYVYLFNLKFQVINSVHDLIKKPVSPNLD
CCCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
SQLKELVQKVVENSNIGKKNVVGMGIGATGIINKEKGLITYSASLGISDYPLLDKVKREY
HHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHC
DFPILLENDTNLAALGEKKFGCGRQLTNFFYIMIGSAIGGGIIIDNEIYRGKFGGAGEFG
CCCEEEECCCCEEEECCCCCCCHHHHHHHHHHEEHHHCCCCEEECCCEEECCCCCCCCCC
HITVEKDGPLCECGNQGCLNAVLTPYITVRSREEFRKSFQEIIKDDNFDSCRYHEFCEYL
EEEEECCCCCCCCCCCCHHHHHHCCEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AMAITNYTKLFDPEAIVLGGEIARIAPERFYIDLEKYIKRMSLKGMNSKIPVLPSSIRTN
HHHHHHHHHHCCCCEEEECCHHHHHCCHHEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCC
AVVLGGACLCFDNLYNNV
EEEECCHHHHHHHHHCCC
>Mature Secondary Structure
MQRGNMKLMKKINRALIIQTLSQQGPLSRADLTKITDLSPTTISSITEELIQEGLIVEVG
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEC
EGESKGGRRPILLDINPEDFYILSVNIAVDVMYVYLFNLKFQVINSVHDLIKKPVSPNLD
CCCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
SQLKELVQKVVENSNIGKKNVVGMGIGATGIINKEKGLITYSASLGISDYPLLDKVKREY
HHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHC
DFPILLENDTNLAALGEKKFGCGRQLTNFFYIMIGSAIGGGIIIDNEIYRGKFGGAGEFG
CCCEEEECCCCEEEECCCCCCCHHHHHHHHHHEEHHHCCCCEEECCCEEECCCCCCCCCC
HITVEKDGPLCECGNQGCLNAVLTPYITVRSREEFRKSFQEIIKDDNFDSCRYHEFCEYL
EEEEECCCCCCCCCCCCHHHHHHCCEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AMAITNYTKLFDPEAIVLGGEIARIAPERFYIDLEKYIKRMSLKGMNSKIPVLPSSIRTN
HHHHHHHHHHCCCCEEEECCHHHHHCCHHEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCC
AVVLGGACLCFDNLYNNV
EEEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]