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The map label for this gene is insF1 [C]

Identifier: 220930878

GI number: 220930878

Start: 35867

End: 36742

Strand: Direct

Name: insF1 [C]

Synonym: Hore_00290

Alternate gene names: 220930878

Gene position: 35867-36742 (Clockwise)

Preceding gene: 220930877

Following gene: 220930879

Centisome position: 1.39

GC content: 35.84

Gene sequence:

>876_bases
ATGATATATGGTTTCATCCGGGATCACAGTAATGAATTTGCTGTGGAGAAGATGTGCCAGGTTTTAAATGTATCCCGGTC
AGGATATTACAGCTGGTTAAATAGAAAACCTGGTAAAAGAGAGTTAACAAATAAAAAGTTAAAGTTGAAGATAGCTGAAA
TATACTGGCAGACCAGGGGAAGGTGTGGTAGCCCCCGGATACATAAACAGCTTAAAAAAGAGGGTTATCATTATAATATT
AAGCGTATTGAACGACTAATGAGGATAATGGGATTAAAAGCAATACAGAAAAGAAAGTTTAAAAGGACAACTAATTCTGA
CAATAATCTCCCTTTAAAAAATAATCTTCTCAAACGTAATTTTAGCGTTACCCAACCTGATAAAGTCTGGGTATCAGACA
TAACATATATTCCAACAAAAGAAGGCTGGCTTTATCTTTCAGTAGTGATTGACCTCTATTCTCGCAAGGTTGTTGGTTGG
TCAATGGACAATCATATGACAAAAAGGTTAGTGATTGATGCATTGGAAATGGCCGTACTAAATCGTAATCCCTCCAGGGG
ATTAATTTTTCATTCTGACAGAGGTAGTCAGTATGCCAGCCATGATTTTCAAAAAACACTGTGGAAATACGGTATTATTT
CATCAATGAGCCGCAAAGGTGATTGCTGGGACAATGCAGTAGCTGAAAGTTTTTTTGCAACACTAAAAACAGAATTGATT
TTCCACAACAAGTATCAGAGCAGGGCTCAGGCAAAACGTGATATATTTGAGTATATAGAGATTTTTTATAATAGGATTCG
ATTACATTCTTCACTAGATTATAAAAGCCCGGAAGATTACGAGAAAGAAAGAAAAACGTCTAAACTATGTGTCTAA

Upstream 100 bases:

>100_bases
AACAGGAAGAAATTCAAAGACTAAAAAAAGAATTAAATGATATAAAAATAGAGCGTGATATATTAAAAAAAGCAGTGCGC
ATCTTCTCAAAGGAACCGAA

Downstream 100 bases:

>100_bases
TTTATTGGGGGAACCCCAAAGGGGTTGTTGTAGCATAAGTCATGCCAATCCTGGCGGAACGGCAACGCAGGAAATGCCAG
GACGTTGGCTGAAATCGGAC

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MIYGFIRDHSNEFAVEKMCQVLNVSRSGYYSWLNRKPGKRELTNKKLKLKIAEIYWQTRGRCGSPRIHKQLKKEGYHYNI
KRIERLMRIMGLKAIQKRKFKRTTNSDNNLPLKNNLLKRNFSVTQPDKVWVSDITYIPTKEGWLYLSVVIDLYSRKVVGW
SMDNHMTKRLVIDALEMAVLNRNPSRGLIFHSDRGSQYASHDFQKTLWKYGIISSMSRKGDCWDNAVAESFFATLKTELI
FHNKYQSRAQAKRDIFEYIEIFYNRIRLHSSLDYKSPEDYEKERKTSKLCV

Sequences:

>Translated_291_residues
MIYGFIRDHSNEFAVEKMCQVLNVSRSGYYSWLNRKPGKRELTNKKLKLKIAEIYWQTRGRCGSPRIHKQLKKEGYHYNI
KRIERLMRIMGLKAIQKRKFKRTTNSDNNLPLKNNLLKRNFSVTQPDKVWVSDITYIPTKEGWLYLSVVIDLYSRKVVGW
SMDNHMTKRLVIDALEMAVLNRNPSRGLIFHSDRGSQYASHDFQKTLWKYGIISSMSRKGDCWDNAVAESFFATLKTELI
FHNKYQSRAQAKRDIFEYIEIFYNRIRLHSSLDYKSPEDYEKERKTSKLCV
>Mature_291_residues
MIYGFIRDHSNEFAVEKMCQVLNVSRSGYYSWLNRKPGKRELTNKKLKLKIAEIYWQTRGRCGSPRIHKQLKKEGYHYNI
KRIERLMRIMGLKAIQKRKFKRTTNSDNNLPLKNNLLKRNFSVTQPDKVWVSDITYIPTKEGWLYLSVVIDLYSRKVVGW
SMDNHMTKRLVIDALEMAVLNRNPSRGLIFHSDRGSQYASHDFQKTLWKYGIISSMSRKGDCWDNAVAESFFATLKTELI
FHNKYQSRAQAKRDIFEYIEIFYNRIRLHSSLDYKSPEDYEKERKTSKLCV

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=260, Percent_Identity=34.2307692307692, Blast_Score=165, Evalue=4e-41,
Organism=Escherichia coli, GI1788405, Length=283, Percent_Identity=42.4028268551237, Blast_Score=244, Evalue=3e-66,
Organism=Escherichia coli, GI1787263, Length=283, Percent_Identity=42.4028268551237, Blast_Score=244, Evalue=3e-66,
Organism=Escherichia coli, GI1786753, Length=283, Percent_Identity=42.4028268551237, Blast_Score=244, Evalue=3e-66,
Organism=Escherichia coli, GI1786570, Length=283, Percent_Identity=42.4028268551237, Blast_Score=244, Evalue=3e-66,
Organism=Escherichia coli, GI1786490, Length=283, Percent_Identity=42.4028268551237, Blast_Score=244, Evalue=3e-66,
Organism=Escherichia coli, GI1789981, Length=275, Percent_Identity=34.9090909090909, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 34573; Mature: 34573

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGFIRDHSNEFAVEKMCQVLNVSRSGYYSWLNRKPGKRELTNKKLKLKIAEIYWQTRG
CEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHCCCHHEEHHHHHHHHHCC
RCGSPRIHKQLKKEGYHYNIKRIERLMRIMGLKAIQKRKFKRTTNSDNNLPLKNNLLKRN
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC
FSVTQPDKVWVSDITYIPTKEGWLYLSVVIDLYSRKVVGWSMDNHMTKRLVIDALEMAVL
CCCCCCCCEEECCEEECCCCCCCCHHHHHHHHHHCHHEEECHHHHHHHHHHHHHHHHHHH
NRNPSRGLIFHSDRGSQYASHDFQKTLWKYGIISSMSRKGDCWDNAVAESFFATLKTELI
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FHNKYQSRAQAKRDIFEYIEIFYNRIRLHSSLDYKSPEDYEKERKTSKLCV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MIYGFIRDHSNEFAVEKMCQVLNVSRSGYYSWLNRKPGKRELTNKKLKLKIAEIYWQTRG
CEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHCCCHHEEHHHHHHHHHCC
RCGSPRIHKQLKKEGYHYNIKRIERLMRIMGLKAIQKRKFKRTTNSDNNLPLKNNLLKRN
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC
FSVTQPDKVWVSDITYIPTKEGWLYLSVVIDLYSRKVVGWSMDNHMTKRLVIDALEMAVL
CCCCCCCCEEECCEEECCCCCCCCHHHHHHHHHHCHHEEECHHHHHHHHHHHHHHHHHHH
NRNPSRGLIFHSDRGSQYASHDFQKTLWKYGIISSMSRKGDCWDNAVAESFFATLKTELI
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FHNKYQSRAQAKRDIFEYIEIFYNRIRLHSSLDYKSPEDYEKERKTSKLCV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]