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The map label for this gene is rnpA

Identifier: 221230946

GI number: 221230946

Start: 3266994

End: 3267356

Strand: Reverse

Name: rnpA

Synonym: MLBr_02712

Alternate gene names: 221230946

Gene position: 3267356-3266994 (Counterclockwise)

Preceding gene: 221230947

Following gene: 221230945

Centisome position: 99.98

GC content: 54.55

Gene sequence:

>363_bases
GTGCTTTCCGCATGTAACCGCATGAGGCGGTCATCCGAGTTTGATGCGACGGTAAAGTTTGGACTGCGCGCAGTGCAGTC
TGATGTTATCATTCACGTTTGGCGTGGGTGTAACAGGGATGAGACGAAGGCTCCCCATGTCGGGCTGATCATAGCTAAAA
CGGTGGGCTCTGCTGTCGAACGTCATCGAGTGGCACGTCGATTGCGGCATGTTGCTCGGACCATGTTGGGGGAATTGGGC
GGAGCTGATCAGGTGGTGATCCGTGCGTTGCCGAGTAGTCGGAATGTGTCGTCAGCATGGTTAGCACAGCAGTTGCGAAA
TGGTTTGAGATGTGCTCTTGATCTGGCAGAGACGGATTGGTGA

Upstream 100 bases:

>100_bases
GCTTCGGATGCGCACGCGTGCTGGCCGGTCGATCGTGTCCGATCGGCGCCGTAAGGGCCGCCGCACATTGACTGCTTGAT
TTGAACGATGGGTTTTAGCG

Downstream 100 bases:

>100_bases
TTCGGTTGGTATCGGCATTTGTAGGATCCGTGGCACAAGTAGGGCCGCGGTGCGTGAACTGATTTTTCTGATCCAGCTTT
ACCGGCACATGATATCGCCG

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MLSACNRMRRSSEFDATVKFGLRAVQSDVIIHVWRGCNRDETKAPHVGLIIAKTVGSAVERHRVARRLRHVARTMLGELG
GADQVVIRALPSSRNVSSAWLAQQLRNGLRCALDLAETDW

Sequences:

>Translated_120_residues
MLSACNRMRRSSEFDATVKFGLRAVQSDVIIHVWRGCNRDETKAPHVGLIIAKTVGSAVERHRVARRLRHVARTMLGELG
GADQVVIRALPSSRNVSSAWLAQQLRNGLRCALDLAETDW
>Mature_120_residues
MLSACNRMRRSSEFDATVKFGLRAVQSDVIIHVWRGCNRDETKAPHVGLIIAKTVGSAVERHRVARRLRHVARTMLGELG
GADQVVIRALPSSRNVSSAWLAQQLRNGLRCALDLAETDW

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_MYCLB (B8ZTN6)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002504362.1
- ProteinModelPortal:   B8ZTN6
- EnsemblBacteria:   EBMYCT00000085544
- GeneID:   7327171
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000016354
- HOGENOM:   HBG728160
- OMA:   LWDSAES
- ProtClustDB:   PRK00588
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 13360; Mature: 13360

Theoretical pI: Translated: 11.51; Mature: 11.51

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSACNRMRRSSEFDATVKFGLRAVQSDVIIHVWRGCNRDETKAPHVGLIIAKTVGSAVE
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RHRVARRLRHVARTMLGELGGADQVVIRALPSSRNVSSAWLAQQLRNGLRCALDLAETDW
HHHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLSACNRMRRSSEFDATVKFGLRAVQSDVIIHVWRGCNRDETKAPHVGLIIAKTVGSAVE
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RHRVARRLRHVARTMLGELGGADQVVIRALPSSRNVSSAWLAQQLRNGLRCALDLAETDW
HHHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA