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The map label for this gene is oxaA

Identifier: 221230945

GI number: 221230945

Start: 3265513

End: 3266655

Strand: Reverse

Name: oxaA

Synonym: MLBr_02710

Alternate gene names: 221230945

Gene position: 3266655-3265513 (Counterclockwise)

Preceding gene: 221230946

Following gene: 221230944

Centisome position: 99.96

GC content: 49.52

Gene sequence:

>1143_bases
GTGAGTCTGTTGCCGTTTGATTTTGTCAGTCTTGACATCGTCTACTATCCGGTGTCGTGGATTATGTGGGTTTGGTACAA
GCTGTTTGCTGCTGTGCTGGGTCCATCAAACTTTTTCGCATGGGCGTTATCGGTGATGTTCTTGGTGTTCACCTTGCGAG
CGTTGCTTTACAAACCGTTCGTGCGCCAGATCCGTACCACTCGGCAGATGCAGGAGTTGCAGCCACGAATTAGAGCGCTG
CAAAGAAAGTACGGTAAAGATCGTCAACGCATGGCGCTCGAGATGCAGAAATTGCAACGCGAGCACGGGTTCAACCCAAT
TTTAGGATGCTTGCCGATGCTTGCGCAGATACCGGTGTTTTTGGGGCTTTACCATGCTTTACGGTCATTCAATCGTACAA
CTGGAGGTTTCGGTCAGCCACATATGTCAGTGACCGAGAACCGGATGACAGGAAATTATGTGTTCACCCCAGTTGACGTG
GGGCATTTTCTTGATGCCAATCTGTGGGGTGCTCCAATTGGTGCGTACATGACGCAACGTTCCGGATTAGATGCGTTCAT
TGATTTCAGTCGTCCAGCGGTGATTTTGGTTGGTATTCCAATGATGGTTTTGGCTGGTGTTGCGACTTACTTCAACAGTC
GCGCTTCAATAGCACGGCAGAGTGCGGAGGCAGCAGAAAATCCGCAGACTGCGTTGATGAACAAAATTGCGTTGTATGTG
TTTCCTTTTGGTGTAGTTGTCGGTGGCCCGTTTCTTCCGTTGGCGATTATTTTGTATTGGTTTTCTAACAATATCTGGAC
TTTTGGTCAACAACATTATGTGTTCTCTATGATCGAGAAAGAAGACGAGGCTAAGAAGCAGAAAGCTATCGAACGTCGGA
CGGCTAACGCGCCTGCGCCAGGCTCTAAGCCAAAGTACGTCTCTACGACGGCACCGGTAAGCGTTAATGGTTTTTCGAAA
GATACCATGATATCCGACGACGGCGCAAAGTTGGGGTCCCAGGAGGCGGACTCTATTGACTGGGTGACTGAAACGAAAAC
AGCTACCACTCCGGCGGATAAGCCGGATTGCGTCGGCTATAACAACAATCCAACCTCTCATACTCGGCGTTCTGGACAGC
GGACAAAGAGACGTAAGCGCTGA

Upstream 100 bases:

>100_bases
TGGGATCCAATACCGGAACGTTGACAGGAACTGCTGAACTGCTGGGCCGGTTTCAATGACGCTAGCGTTGCTTGGAGTTG
CCCATCGAAGCTAGGAGAGG

Downstream 100 bases:

>100_bases
CGAGGTGTCAAAATTTTTACTGGGTCGAGTTCGTTGAATGACTTAAGAGGGCATGGACTTGTGGATTGAGAAAGAGAAGC
CATGACAGATGTTGAAACTA

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSLLPFDFVSLDIVYYPVSWIMWVWYKLFAAVLGPSNFFAWALSVMFLVFTLRALLYKPFVRQIRTTRQMQELQPRIRAL
QRKYGKDRQRMALEMQKLQREHGFNPILGCLPMLAQIPVFLGLYHALRSFNRTTGGFGQPHMSVTENRMTGNYVFTPVDV
GHFLDANLWGAPIGAYMTQRSGLDAFIDFSRPAVILVGIPMMVLAGVATYFNSRASIARQSAEAAENPQTALMNKIALYV
FPFGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFSMIEKEDEAKKQKAIERRTANAPAPGSKPKYVSTTAPVSVNGFSK
DTMISDDGAKLGSQEADSIDWVTETKTATTPADKPDCVGYNNNPTSHTRRSGQRTKRRKR

Sequences:

>Translated_380_residues
MSLLPFDFVSLDIVYYPVSWIMWVWYKLFAAVLGPSNFFAWALSVMFLVFTLRALLYKPFVRQIRTTRQMQELQPRIRAL
QRKYGKDRQRMALEMQKLQREHGFNPILGCLPMLAQIPVFLGLYHALRSFNRTTGGFGQPHMSVTENRMTGNYVFTPVDV
GHFLDANLWGAPIGAYMTQRSGLDAFIDFSRPAVILVGIPMMVLAGVATYFNSRASIARQSAEAAENPQTALMNKIALYV
FPFGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFSMIEKEDEAKKQKAIERRTANAPAPGSKPKYVSTTAPVSVNGFSK
DTMISDDGAKLGSQEADSIDWVTETKTATTPADKPDCVGYNNNPTSHTRRSGQRTKRRKR
>Mature_379_residues
SLLPFDFVSLDIVYYPVSWIMWVWYKLFAAVLGPSNFFAWALSVMFLVFTLRALLYKPFVRQIRTTRQMQELQPRIRALQ
RKYGKDRQRMALEMQKLQREHGFNPILGCLPMLAQIPVFLGLYHALRSFNRTTGGFGQPHMSVTENRMTGNYVFTPVDVG
HFLDANLWGAPIGAYMTQRSGLDAFIDFSRPAVILVGIPMMVLAGVATYFNSRASIARQSAEAAENPQTALMNKIALYVF
PFGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFSMIEKEDEAKKQKAIERRTANAPAPGSKPKYVSTTAPVSVNGFSKD
TMISDDGAKLGSQEADSIDWVTETKTATTPADKPDCVGYNNNPTSHTRRSGQRTKRRKR

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=270, Percent_Identity=24.8148148148148, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_MYCLE (Q50205)

Other databases:

- EMBL:   L39923
- EMBL:   AL583926
- PIR:   D87248
- RefSeq:   NP_302731.1
- EnsemblBacteria:   EBMYCT00000029280
- GeneID:   908248
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML2710
- NMPDR:   fig|272631.1.peg.1603
- Leproma:   ML2710
- GeneTree:   EBGT00050000017449
- HOGENOM:   HBG560622
- OMA:   FIGLFHV
- ProtClustDB:   PRK03449
- BioCyc:   MLEP272631:ML2710-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 42879; Mature: 42748

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x462c186c)-; HASH(0x463f4520)-; HASH(0x463f5018)-; HASH(0x463f4124)-; HASH(0x463f4268)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLPFDFVSLDIVYYPVSWIMWVWYKLFAAVLGPSNFFAWALSVMFLVFTLRALLYKPF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VRQIRTTRQMQELQPRIRALQRKYGKDRQRMALEMQKLQREHGFNPILGCLPMLAQIPVF
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LGLYHALRSFNRTTGGFGQPHMSVTENRMTGNYVFTPVDVGHFLDANLWGAPIGAYMTQR
HHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCEEEECCCHHHHHCCCCCCCCHHHHHHHC
SGLDAFIDFSRPAVILVGIPMMVLAGVATYFNSRASIARQSAEAAENPQTALMNKIALYV
CCCHHEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FPFGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFSMIEKEDEAKKQKAIERRTANAPAP
HHHHHHHCCHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GSKPKYVSTTAPVSVNGFSKDTMISDDGAKLGSQEADSIDWVTETKTATTPADKPDCVGY
CCCCCEEECCCCEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NNNPTSHTRRSGQRTKRRKR
CCCCCHHHHHHHHHHHHCCH
>Mature Secondary Structure 
SLLPFDFVSLDIVYYPVSWIMWVWYKLFAAVLGPSNFFAWALSVMFLVFTLRALLYKPF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VRQIRTTRQMQELQPRIRALQRKYGKDRQRMALEMQKLQREHGFNPILGCLPMLAQIPVF
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LGLYHALRSFNRTTGGFGQPHMSVTENRMTGNYVFTPVDVGHFLDANLWGAPIGAYMTQR
HHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCEEEECCCHHHHHCCCCCCCCHHHHHHHC
SGLDAFIDFSRPAVILVGIPMMVLAGVATYFNSRASIARQSAEAAENPQTALMNKIALYV
CCCHHEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FPFGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFSMIEKEDEAKKQKAIERRTANAPAP
HHHHHHHCCHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GSKPKYVSTTAPVSVNGFSKDTMISDDGAKLGSQEADSIDWVTETKTATTPADKPDCVGY
CCCCCEEECCCCEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NNNPTSHTRRSGQRTKRRKR
CCCCCHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969512; 11234002