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The map label for this gene is aspC [H]

Identifier: 221230831

GI number: 221230831

Start: 2982699

End: 2984012

Strand: Direct

Name: aspC [H]

Synonym: MLBr_02502

Alternate gene names: 221230831

Gene position: 2982699-2984012 (Clockwise)

Preceding gene: 221230830

Following gene: 221230847

Centisome position: 91.27

GC content: 58.68

Gene sequence:

>1314_bases
TTGACACTATATCAGCAAATTTCAGTGGACGGCAGTGGCACCATGAGTGACGTGACTACTCACCAGCTGCCCATGCACAC
CCCTGGCTATCACCGGCAACGTGCCTTCGCGCAGTCGTCCAAGCTTCAGGACGTCCTCTACGAAATCCGTGGCCCGGTGA
GCCAGCATGCCACACGACTAGAAACTGAAGGACACCGCATCCTCAAACTGAATATCGGTAACCCAGCGCTGTTCGGGTTC
GACGCACCTGACGTAATTATGCGCGACATGATCCAGGCGCTGCCGTACGCGCAGGGGTACTCCGACTCCCAGGGCATCCT
GCCTGCACGTCGCGCGGTGGTTACCCGCTACGAGCTGGTCGACGGGTTCCCCCGATTCGACGTCGATGACGTCTATCTCG
GCAACGGCGTCTCCGAGCTGATCACGATGACGCTGCAGGCCCTGTTAGACAACGGCGATCAGGTGCTGATCCCCTCGCCG
GACTACCCGCTGTGGACAGCGTCGACCTCGCTGGCCGGTGGCACACCCGTACATTACCTCTGCGACGAAACCCAAGGCTG
GCAACCAGATATCGCCGACGTGGAATCTAAGATCACCGAGCGCACCAAAGCACTGGTCGTGATCAACCCCAACAACCCTA
CCGGCGCCGTCTACAGCAACGAAATCCTTAACCAAATAGTCGACCTAGCACGTAAGCATCAGCTGCTGCTGCTTGCCGAC
GAGATCTACGACAAGATTCTCTATGACGACACCAAGCACATCAGCGTGGCCTCAATTGCGCCTGATCTACTGTGCTTGAC
CTTCAACGGTCTTTCGAAAGCCTACCGTGTCGCCGGGTACCGGTCCGGCTGGCTAGCGATCACCGGGCCCAAGGACCATG
CCAGTAGCTTCATTGGGGGGATCAATCTACTGGCCAATATGCGGTTATGCCCGAATGTTCCTGCGCAGCATGCGATCCAG
GTAGCCCTCGGTGGCCACCAGAGCATCGAAGACTTGGTGCTACCGGGCGGTCGGCTGCTCGAGCAGCGTGACGTCGCCTG
GACCAAACTGAACGAGATCCCGGGGGTGTCATGCGTCAAACCCACCGGTGCACTGTATGCCTTTCCCCGGCTAGATCCAG
AAGTCTATGGCATCGTCGATGACGAGCAACTGGTCCTCGACCTGCTACTACAAGAGAAGATCCTGGTCACCCAGGGCAGC
GGATTCAATTGGCCGGCACCGGATCATCTGCGCTTGGTGACGCTGCCGTGGTCTCGTGACCTTGCGGCTGCGATCGACCG
GCTCGGTAACTTCTTGGTCAGTTACCGTCAATAG

Upstream 100 bases:

>100_bases
CTGACCATGCCGATGGCAACCCGGCTCCGCCAACCGCGCCCGTCAAAAGGCTGGGCATCACACGGAGCGCACGTCCGCCG
GGCAAGCACTGACCAAGAGA

Downstream 100 bases:

>100_bases
TTTGCTCAGCACCGCAGACCGAACACAGGGCGAAGTGCTGACCAGCGAGAACGTGTCATCGAGTTGGTGCGCTCGGCGGT
GGATGGCATAGCGCTTGCTC

Product: aminotransferase AlaT

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTLYQQISVDGSGTMSDVTTHQLPMHTPGYHRQRAFAQSSKLQDVLYEIRGPVSQHATRLETEGHRILKLNIGNPALFGF
DAPDVIMRDMIQALPYAQGYSDSQGILPARRAVVTRYELVDGFPRFDVDDVYLGNGVSELITMTLQALLDNGDQVLIPSP
DYPLWTASTSLAGGTPVHYLCDETQGWQPDIADVESKITERTKALVVINPNNPTGAVYSNEILNQIVDLARKHQLLLLAD
EIYDKILYDDTKHISVASIAPDLLCLTFNGLSKAYRVAGYRSGWLAITGPKDHASSFIGGINLLANMRLCPNVPAQHAIQ
VALGGHQSIEDLVLPGGRLLEQRDVAWTKLNEIPGVSCVKPTGALYAFPRLDPEVYGIVDDEQLVLDLLLQEKILVTQGS
GFNWPAPDHLRLVTLPWSRDLAAAIDRLGNFLVSYRQ

Sequences:

>Translated_437_residues
MTLYQQISVDGSGTMSDVTTHQLPMHTPGYHRQRAFAQSSKLQDVLYEIRGPVSQHATRLETEGHRILKLNIGNPALFGF
DAPDVIMRDMIQALPYAQGYSDSQGILPARRAVVTRYELVDGFPRFDVDDVYLGNGVSELITMTLQALLDNGDQVLIPSP
DYPLWTASTSLAGGTPVHYLCDETQGWQPDIADVESKITERTKALVVINPNNPTGAVYSNEILNQIVDLARKHQLLLLAD
EIYDKILYDDTKHISVASIAPDLLCLTFNGLSKAYRVAGYRSGWLAITGPKDHASSFIGGINLLANMRLCPNVPAQHAIQ
VALGGHQSIEDLVLPGGRLLEQRDVAWTKLNEIPGVSCVKPTGALYAFPRLDPEVYGIVDDEQLVLDLLLQEKILVTQGS
GFNWPAPDHLRLVTLPWSRDLAAAIDRLGNFLVSYRQ
>Mature_436_residues
TLYQQISVDGSGTMSDVTTHQLPMHTPGYHRQRAFAQSSKLQDVLYEIRGPVSQHATRLETEGHRILKLNIGNPALFGFD
APDVIMRDMIQALPYAQGYSDSQGILPARRAVVTRYELVDGFPRFDVDDVYLGNGVSELITMTLQALLDNGDQVLIPSPD
YPLWTASTSLAGGTPVHYLCDETQGWQPDIADVESKITERTKALVVINPNNPTGAVYSNEILNQIVDLARKHQLLLLADE
IYDKILYDDTKHISVASIAPDLLCLTFNGLSKAYRVAGYRSGWLAITGPKDHASSFIGGINLLANMRLCPNVPAQHAIQV
ALGGHQSIEDLVLPGGRLLEQRDVAWTKLNEIPGVSCVKPTGALYAFPRLDPEVYGIVDDEQLVLDLLLQEKILVTQGSG
FNWPAPDHLRLVTLPWSRDLAAAIDRLGNFLVSYRQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=467, Percent_Identity=25.6959314775161, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI215599424, Length=372, Percent_Identity=27.9569892473118, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI4507369, Length=421, Percent_Identity=25.8907363420428, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI4885351, Length=435, Percent_Identity=27.5862068965517, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI95147551, Length=170, Percent_Identity=35.8823529411765, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI169881279, Length=170, Percent_Identity=35.8823529411765, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI56713254, Length=152, Percent_Identity=32.8947368421053, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI56713256, Length=152, Percent_Identity=32.8947368421053, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI169881281, Length=151, Percent_Identity=34.4370860927152, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI149944424, Length=340, Percent_Identity=25.2941176470588, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1788627, Length=400, Percent_Identity=59.75, Blast_Score=529, Evalue=1e-151,
Organism=Escherichia coli, GI1788722, Length=392, Percent_Identity=26.2755102040816, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786816, Length=302, Percent_Identity=24.1721854304636, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17567663, Length=378, Percent_Identity=29.3650793650794, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI71981209, Length=459, Percent_Identity=25.4901960784314, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=151, Percent_Identity=35.7615894039735, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71994476, Length=151, Percent_Identity=35.7615894039735, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71981215, Length=294, Percent_Identity=27.5510204081633, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17567369, Length=164, Percent_Identity=30.4878048780488, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320317, Length=471, Percent_Identity=26.5392781316348, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6323118, Length=504, Percent_Identity=26.1904761904762, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6322401, Length=237, Percent_Identity=25.3164556962025, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=29.1777188328912, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI45551451, Length=468, Percent_Identity=26.2820512820513, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24641770, Length=468, Percent_Identity=26.2820512820513, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24641760, Length=468, Percent_Identity=26.2820512820513, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24641768, Length=468, Percent_Identity=26.2820512820513, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24641766, Length=468, Percent_Identity=26.2820512820513, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24641764, Length=468, Percent_Identity=26.2820512820513, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28573069, Length=262, Percent_Identity=25.5725190839695, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646114, Length=262, Percent_Identity=25.5725190839695, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28573067, Length=262, Percent_Identity=25.5725190839695, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28573065, Length=262, Percent_Identity=25.5725190839695, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 48187; Mature: 48055

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLYQQISVDGSGTMSDVTTHQLPMHTPGYHRQRAFAQSSKLQDVLYEIRGPVSQHATRL
CCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ETEGHRILKLNIGNPALFGFDAPDVIMRDMIQALPYAQGYSDSQGILPARRAVVTRYELV
CCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
DGFPRFDVDDVYLGNGVSELITMTLQALLDNGDQVLIPSPDYPLWTASTSLAGGTPVHYL
CCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCCCCCCEEEE
CDETQGWQPDIADVESKITERTKALVVINPNNPTGAVYSNEILNQIVDLARKHQLLLLAD
ECCCCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCEEHHHHHHHHHHHHHHCCEEEEHH
EIYDKILYDDTKHISVASIAPDLLCLTFNGLSKAYRVAGYRSGWLAITGPKDHASSFIGG
HHHHHHHCCCCCCEEEHHCCCCEEEEEEHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHH
INLLANMRLCPNVPAQHAIQVALGGHQSIEDLVLPGGRLLEQRDVAWTKLNEIPGVSCVK
HHHHHCCCCCCCCCHHHEEEEEECCCCCHHHHHCCCCHHHHHCCCHHHHHHCCCCCCEEC
PTGALYAFPRLDPEVYGIVDDEQLVLDLLLQEKILVTQGSGFNWPAPDHLRLVTLPWSRD
CCCCEEECCCCCCCEEEEECCHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEECCCCCH
LAAAIDRLGNFLVSYRQ
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLYQQISVDGSGTMSDVTTHQLPMHTPGYHRQRAFAQSSKLQDVLYEIRGPVSQHATRL
CCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ETEGHRILKLNIGNPALFGFDAPDVIMRDMIQALPYAQGYSDSQGILPARRAVVTRYELV
CCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
DGFPRFDVDDVYLGNGVSELITMTLQALLDNGDQVLIPSPDYPLWTASTSLAGGTPVHYL
CCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCCCCCCEEEE
CDETQGWQPDIADVESKITERTKALVVINPNNPTGAVYSNEILNQIVDLARKHQLLLLAD
ECCCCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCEEHHHHHHHHHHHHHHCCEEEEHH
EIYDKILYDDTKHISVASIAPDLLCLTFNGLSKAYRVAGYRSGWLAITGPKDHASSFIGG
HHHHHHHCCCCCCEEEHHCCCCEEEEEEHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHH
INLLANMRLCPNVPAQHAIQVALGGHQSIEDLVLPGGRLLEQRDVAWTKLNEIPGVSCVK
HHHHHCCCCCCCCCHHHEEEEEECCCCCHHHHHCCCCHHHHHCCCHHHHHHCCCCCCEEC
PTGALYAFPRLDPEVYGIVDDEQLVLDLLLQEKILVTQGSGFNWPAPDHLRLVTLPWSRD
CCCCEEECCCCCCCEEEEECCHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEECCCCCH
LAAAIDRLGNFLVSYRQ
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]