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The map label for this gene is 221230696

Identifier: 221230696

GI number: 221230696

Start: 2698832

End: 2700058

Strand: Reverse

Name: 221230696

Synonym: MLBr_02276

Alternate gene names: NA

Gene position: 2700058-2698832 (Counterclockwise)

Preceding gene: 221230699

Following gene: 221230695

Centisome position: 82.62

GC content: 62.43

Gene sequence:

>1227_bases
GTGAGGGTGGAGACTAGCGCAGACGTGGTAGTGGTGGGCGCCGGACCAGCGGGGTCAGCTGCAGCCACCTGGGCGGCACG
CGCCGGTAATGATGTAATCGTCATCGATTCGGTTTGCTTTCCTCGAGACAAGGCCTGCGGTGACGGGTTGACTCCGCGCG
CGGTCGCTGAGCTGAAACGGCTAGGGCTGGACGACTGGCTAAATACCCGCATCCGACATCGCGGTCTACGAATGAGCGGC
TTTGGCGGCGAAGTGGAAGTGGATTGGCCCGGCCCGTCGTTCCCGTCAACCAGCAGTGCGGTGCCACGACTAGAATTAGA
TGACCGGATACGTAAGGTCGCCGAGAATTCCGGGGCCCGCATGTTGCTCGGGACTAAAGCTGTCTCGGTTTACCATGATT
CATCGAGACGGGCAGCATCAGTGACGTTGGCCGACGGCACCGAGGTTGGCTGCCGCCAGTTAATTATTGCCGACGGGGCC
CGGTCTCCGCTGGGTCGCAAGCTAGGCCGGAGCTGGCATCAAAAGACCGTGTACGGCGTTGCTGCCCGTGGGTACCTGAC
CACTCCGCGCAGCGACGACCTCTGGCTGACATCGCATCTGGAACTACGTTCCCCCGACGGAGCCGTGCTGCCTGGATACG
GCTGGATTTTCCCGCTGGGCAACGGCGAGGTGAATATCGGCGTTGGAGCGTTGTCGACATCAAAGCGGCCAGCCGACCTG
GCGTTGCGATCGCTGATCTCGTACTATACAGATCTACGCCGTCACGAGTGGGGCTTTTCCGGCCAACCGCGGGCGGTCTC
GTCGGCGTTGTTGCCGATGGGGGGCGCTGTTTCCGGAGTAGCCGGACCAAACTGGATGCTCATCGGTGATGCTGCAGCGT
GCGTCAACCCGCTCAACGGCGAAGGCATTGACTACGGTCTAGAAACAGGCCGGCTGGCCGCCGAGCTGCTGGACTTGCGC
GATTTGTCGTACGTGTGGCCTTCGCTGCTGCAGCAGCATTATGGTCGCGGATTTTCGGTCGCACGCCGGCTGGCGTTGTT
GCTGACCTTCAAACGGTGTCTGCCCGCGATCGGTCCGAGCGCGATGCGCTCTACTTCACTGATAACCATAGCCGTGCGGG
TGATGGCCAATCTGGTCACCGACGACGATGCCGACTGGGTGGCGCGGGTGTGGCGAAGCGGCGGGTGGGCATCATGGCTC
GTCGATCGCCGACCACCGTTCAGCTAG

Upstream 100 bases:

>100_bases
TCCTCACTACCCTGTCTTGTACAGTCGCCGCAAACGCAGCGTCTCCGAAATTAATGCCCGCTACCACCATCGGCGTAGTC
GTCATCCAACCAACATACTA

Downstream 100 bases:

>100_bases
TCCAATTTTGCCCTTCTCTCGCAATAACAATTGCATTGGCATATGCCAGAGCGGTCGATATACATGGGGTCATGACCACG
GGAGGCCGGGTAGCGAGGTC

Product: putative FAD-linked oxidoreductase

Products: NA

Alternate protein names: DGGGPL reductase 1; 2,3-di-O-geranylgeranylglyceryl phosphate reductase 1; Geranylgeranyl reductase 1; GGR 1 [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MRVETSADVVVVGAGPAGSAAATWAARAGNDVIVIDSVCFPRDKACGDGLTPRAVAELKRLGLDDWLNTRIRHRGLRMSG
FGGEVEVDWPGPSFPSTSSAVPRLELDDRIRKVAENSGARMLLGTKAVSVYHDSSRRAASVTLADGTEVGCRQLIIADGA
RSPLGRKLGRSWHQKTVYGVAARGYLTTPRSDDLWLTSHLELRSPDGAVLPGYGWIFPLGNGEVNIGVGALSTSKRPADL
ALRSLISYYTDLRRHEWGFSGQPRAVSSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGLETGRLAAELLDLR
DLSYVWPSLLQQHYGRGFSVARRLALLLTFKRCLPAIGPSAMRSTSLITIAVRVMANLVTDDDADWVARVWRSGGWASWL
VDRRPPFS

Sequences:

>Translated_408_residues
MRVETSADVVVVGAGPAGSAAATWAARAGNDVIVIDSVCFPRDKACGDGLTPRAVAELKRLGLDDWLNTRIRHRGLRMSG
FGGEVEVDWPGPSFPSTSSAVPRLELDDRIRKVAENSGARMLLGTKAVSVYHDSSRRAASVTLADGTEVGCRQLIIADGA
RSPLGRKLGRSWHQKTVYGVAARGYLTTPRSDDLWLTSHLELRSPDGAVLPGYGWIFPLGNGEVNIGVGALSTSKRPADL
ALRSLISYYTDLRRHEWGFSGQPRAVSSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGLETGRLAAELLDLR
DLSYVWPSLLQQHYGRGFSVARRLALLLTFKRCLPAIGPSAMRSTSLITIAVRVMANLVTDDDADWVARVWRSGGWASWL
VDRRPPFS
>Mature_408_residues
MRVETSADVVVVGAGPAGSAAATWAARAGNDVIVIDSVCFPRDKACGDGLTPRAVAELKRLGLDDWLNTRIRHRGLRMSG
FGGEVEVDWPGPSFPSTSSAVPRLELDDRIRKVAENSGARMLLGTKAVSVYHDSSRRAASVTLADGTEVGCRQLIIADGA
RSPLGRKLGRSWHQKTVYGVAARGYLTTPRSDDLWLTSHLELRSPDGAVLPGYGWIFPLGNGEVNIGVGALSTSKRPADL
ALRSLISYYTDLRRHEWGFSGQPRAVSSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGLETGRLAAELLDLR
DLSYVWPSLLQQHYGRGFSVARRLALLLTFKRCLPAIGPSAMRSTSLITIAVRVMANLVTDDDADWVARVWRSGGWASWL
VDRRPPFS

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR011777
- InterPro:   IPR003042 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 43886; Mature: 43886

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVETSADVVVVGAGPAGSAAATWAARAGNDVIVIDSVCFPRDKACGDGLTPRAVAELKR
CCCCCCCCEEEEECCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHH
LGLDDWLNTRIRHRGLRMSGFGGEVEVDWPGPSFPSTSSAVPRLELDDRIRKVAENSGAR
CCCHHHHHHHHHHCCCEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCE
MLLGTKAVSVYHDSSRRAASVTLADGTEVGCRQLIIADGARSPLGRKLGRSWHQKTVYGV
EEEECEEEEEEECCCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHEE
AARGYLTTPRSDDLWLTSHLELRSPDGAVLPGYGWIFPLGNGEVNIGVGALSTSKRPADL
EECCEEECCCCCCEEEEEEEEEECCCCCEECCCCEEEECCCCEEEEEEEECCCCCCCHHH
ALRSLISYYTDLRRHEWGFSGQPRAVSSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNG
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHCCCCCC
EGIDYGLETGRLAAELLDLRDLSYVWPSLLQQHYGRGFSVARRLALLLTFKRCLPAIGPS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHH
AMRSTSLITIAVRVMANLVTDDDADWVARVWRSGGWASWLVDRRPPFS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCC
>Mature Secondary Structure
MRVETSADVVVVGAGPAGSAAATWAARAGNDVIVIDSVCFPRDKACGDGLTPRAVAELKR
CCCCCCCCEEEEECCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHH
LGLDDWLNTRIRHRGLRMSGFGGEVEVDWPGPSFPSTSSAVPRLELDDRIRKVAENSGAR
CCCHHHHHHHHHHCCCEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCE
MLLGTKAVSVYHDSSRRAASVTLADGTEVGCRQLIIADGARSPLGRKLGRSWHQKTVYGV
EEEECEEEEEEECCCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHEE
AARGYLTTPRSDDLWLTSHLELRSPDGAVLPGYGWIFPLGNGEVNIGVGALSTSKRPADL
EECCEEECCCCCCEEEEEEEEEECCCCCEECCCCEEEECCCCEEEEEEEECCCCCCCHHH
ALRSLISYYTDLRRHEWGFSGQPRAVSSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNG
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHCCCCCC
EGIDYGLETGRLAAELLDLRDLSYVWPSLLQQHYGRGFSVARRLALLLTFKRCLPAIGPS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHH
AMRSTSLITIAVRVMANLVTDDDADWVARVWRSGGWASWLVDRRPPFS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA