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The map label for this gene is cdd [H]

Identifier: 221230641

GI number: 221230641

Start: 2586072

End: 2586476

Strand: Direct

Name: cdd [H]

Synonym: MLBr_02174

Alternate gene names: 221230641

Gene position: 2586072-2586476 (Clockwise)

Preceding gene: 221230640

Following gene: 221230642

Centisome position: 79.13

GC content: 57.04

Gene sequence:

>405_bases
ATGGGTGACGTGAATTGGGACACGCTGCAGAAGGCCGCGGTCGCGGCCAGAGCGAATTCCTATGCGCCCTACTCGAATTT
CCCGGTCGGGGTAGCTGGGTTCGTCAACGACGGCCGGCTCATTACAGGGGTGAATGTTGAGAACGCTTCATACGGACTCG
CGCTATGTGCCGAGTGTTCGATGATTTCGGCATTATACGCTACCGGTGGTGGCCGACTTGTTGCCGTCTACTGCGTCGAC
GGCAACGGGGACTCGCTCATGCCATGCGGTCGCTGTCGCCAATTGCTTTACGAGCATGGCGGACCCGAACTGAAAATCAT
GACCCCGAAAGGCGTGCAGACAATGGCCCAGCTCCTTCCCCAAGCATTCAACCCGCAGGAAAGGATATTCGGAAATGACG
AATAA

Upstream 100 bases:

>100_bases
TGAAGTCGGCATCACATTTCAGGGCATCTGCCGATGCTAGATTGACGCAGTCAGTTGGACGTCGGTTACGCATCGGTGTT
CACGCTGGAGGTCCGGTCAG

Downstream 100 bases:

>100_bases
GACCACCGTGGAGACGATCGCAATCGACGGCCGCACAGCCAGCAAGGCAACGTGGGCGATTCGGGCCGCTATGAGTTTCG
GCGCCTCGTCGCACAAATGT

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MGDVNWDTLQKAAVAARANSYAPYSNFPVGVAGFVNDGRLITGVNVENASYGLALCAECSMISALYATGGGRLVAVYCVD
GNGDSLMPCGRCRQLLYEHGGPELKIMTPKGVQTMAQLLPQAFNPQERIFGNDE

Sequences:

>Translated_134_residues
MGDVNWDTLQKAAVAARANSYAPYSNFPVGVAGFVNDGRLITGVNVENASYGLALCAECSMISALYATGGGRLVAVYCVD
GNGDSLMPCGRCRQLLYEHGGPELKIMTPKGVQTMAQLLPQAFNPQERIFGNDE
>Mature_133_residues
GDVNWDTLQKAAVAARANSYAPYSNFPVGVAGFVNDGRLITGVNVENASYGLALCAECSMISALYATGGGRLVAVYCVDG
NGDSLMPCGRCRQLLYEHGGPELKIMTPKGVQTMAQLLPQAFNPQERIFGNDE

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=117, Percent_Identity=39.3162393162393, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17540514, Length=128, Percent_Identity=36.71875, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551074, Length=122, Percent_Identity=37.7049180327869, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323274, Length=133, Percent_Identity=39.0977443609023, Blast_Score=82, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24582741, Length=123, Percent_Identity=34.1463414634146, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14251; Mature: 14120

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDVNWDTLQKAAVAARANSYAPYSNFPVGVAGFVNDGRLITGVNVENASYGLALCAECS
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHH
MISALYATGGGRLVAVYCVDGNGDSLMPCGRCRQLLYEHGGPELKIMTPKGVQTMAQLLP
HHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
QAFNPQERIFGNDE
HHCCCHHHCCCCCC
>Mature Secondary Structure 
GDVNWDTLQKAAVAARANSYAPYSNFPVGVAGFVNDGRLITGVNVENASYGLALCAECS
CCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHH
MISALYATGGGRLVAVYCVDGNGDSLMPCGRCRQLLYEHGGPELKIMTPKGVQTMAQLLP
HHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
QAFNPQERIFGNDE
HHCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]