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The map label for this gene is 221230634

Identifier: 221230634

GI number: 221230634

Start: 2559261

End: 2560910

Strand: Direct

Name: 221230634

Synonym: MLBr_02157

Alternate gene names: NA

Gene position: 2559261-2560910 (Clockwise)

Preceding gene: 221230633

Following gene: 221230638

Centisome position: 78.31

GC content: 59.88

Gene sequence:

>1650_bases
ATGACCGACGGGCCGTTGATAGTGCAGTCCGATAAAACGGTGCTGCTCGAAGTGAACCATAAGCTAGCCGATGCGGCACG
TGCAGCCATAGCACCGTTCGCCGAGCTGGAACGCGCACCCGAACACGTACACACCTACCGCATCACACCACTAGCGTTGT
GGAACGCCCGCGCCGCAGGTCATGACGCCGAACAAGTCGTCGACACGTTGATCAGTCATGCGCGCTACGCAGTGCCACAG
CCTCTGCTGGTCGACATCGTCGACACCATGGCCCGCTATGGGCGGCTGCAACTGGTCAAGAATCCCGCCCACGGCCTGAC
GCTGGTAAGCCTGGATCGCACGGTACTGGAGGAGGTGTTACATAACAAGAAGATCGCACCGATGGTGGGCGGCCGCATCG
ACGACGACACAGTCGTCGTCCATCCCAGCGAACGTGGCCGGATCAAACAGCTTTTGCTTAAGATCGGTTGGCCCGCAGAG
GATCTCGCTGGTTACGTGGATGGTGAGGCGCACCCGATTATCCTGCATCAGGACGGTTGGCAGCTGCGCGATTACCAGCG
GCTAGCAGCCGATTCATTCTGGTCTGGCGGCTCCGGGGTGGTAGTGCTGCCATGTGGCGCTGGCAAAACGCTAGTGGGGG
CGGCCGCGATGGCGAAAACCGGTGCGACGACGCTCATTTTAGTCACCAACATCGTGGTTGCCCGACAGTGGAAACGCGAG
TTGATCACGCACACCTCGCTGACCGAGGACGAGATCGGCGAATACTCCGGAGAGCGCAAGGAAATCCGACCGGTGACCAT
CTCGACCTACCAGATGATCACCCACCGCACCAAAGGAGAGTATCGTCATCTGGAACTCTTCAATAGCCGCGACTGGGGCC
TGATCATCTACGACGAGGTGCATCTGTTGCCCGCACCGGTGTTCCGGATGACCGCTGACCTGCAGTCCAAGCGGCGGCTG
GGCCTGACCGCCACGTTGATCCGCGAAGACGGCCGCGAAGGTGACGTGTTTTCCCTGATCGGCCCGAAACGCTATGACAC
GCCGTGGAAGGACCTTGAGGAACAAGGCTGGATCGCGCCAGCAAAGTGCGTCGAAGTCCGGGTCACGTTGACGAATAACG
AAAGGATGACCTACGCCACAGCCGAACCCGAAGAACGCTACCGTGTCTGCTCGACAGCGCATTCGAAGATTGCAGTGGTT
AAGTCGGTGCTGAGCCGACACCCCGGCGAGCAAACCCTCGTGATCGGTGCCTACCTGGATCAGCTCAACGAACTTGGTTC
CGAGCTCAACGCTCCAATCATTCAAGGATCAACGAGAACCAAAGAACGCGAAGCGCTATTCGACGCTTTCCGCCGCGGTG
AAGTCTTCACACTGGTGGTCTCCAAGGTTGCCAACTTCTCCATAGATTTGCCGGAAGCCGCTGTTGCGGTACAAGTTTCG
GGAACTTTTGGCTCACGTCAAGAGGAAGCGCAGCGGCTGGGCCGGTTGCTGCGACCTAAGGCCGACGGCGGTGGAGCGAT
CTTCTACTCCGTGGTTGCCCGCGACAGCCTGGACGCCGAATACGCCGCACACCGGCAGCGATTCTTAGCCGAGCAAGGCT
ACAGCTACATCATCCGCGACGCCGACGACCTGCTGGGCCCGGCGATCTAG

Upstream 100 bases:

>100_bases
CGGGCGGCTACGTGACTTTGTCATCCACCGCATCACGTCAGTGGTGTCGTCCGACAGCCAATAATGGACTCTCACGAAAC
GACGAGAAGGAGCAGCACTA

Downstream 100 bases:

>100_bases
CCTGACAGAGTGATCGCTAACGAGATTTCATGCATGCCGTACACTTGGACCAGACCAACACGCGAATTGCCGGACACCTG
ACGCTCGCCCGCCTTGCCTC

Product: putative DNA helicase

Products: NA

Alternate protein names: DNA Repair Helicase; Type III Restriction Res Subunit; Helicase Domain-Containing Protein; Helicase Domain Protein; ATP-Dependent DNA Helicase; DNA Repair Helicase RAD; DNA Repair Helicase Rad; Type III Restriction Res Subunit Family; DNA Repair Protein Rad; Superfamily II DNA/RNA Helicase; Helicase; DNA/RNA Helicase; DNA Repair Protein; DNA Repair Protein RAD; DNA Helicase; DNA/RNA Helicase Superfamily II; Helicase-Like Protein; Helicase Protein; ATP-Dependent Helicase; DNA Or RNA Helicase Of Superfamily II; Helicase DNA Repair; Helicase DNA Repair Rad; XPB/RAD25-Related Helicase; DEAD/DEAH Box Helicase-Like; DNA-Helicase; DNA/RNA Repair Helicase; DNA Or RNA Helicase Of Superfamily Protein II; DEAD/DEAH Box Helicase; Helicase ATP-Dependent; DNA Or RNA Helicase; RAD25-Type DNA Repair Helicase; DNA Repair Related Protein; Restriction Endonuclease Family Protein; Helicase ATP-Dependent Intein-Containing

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MTDGPLIVQSDKTVLLEVNHKLADAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAEQVVDTLISHARYAVPQ
PLLVDIVDTMARYGRLQLVKNPAHGLTLVSLDRTVLEEVLHNKKIAPMVGGRIDDDTVVVHPSERGRIKQLLLKIGWPAE
DLAGYVDGEAHPIILHQDGWQLRDYQRLAADSFWSGGSGVVVLPCGAGKTLVGAAAMAKTGATTLILVTNIVVARQWKRE
LITHTSLTEDEIGEYSGERKEIRPVTISTYQMITHRTKGEYRHLELFNSRDWGLIIYDEVHLLPAPVFRMTADLQSKRRL
GLTATLIREDGREGDVFSLIGPKRYDTPWKDLEEQGWIAPAKCVEVRVTLTNNERMTYATAEPEERYRVCSTAHSKIAVV
KSVLSRHPGEQTLVIGAYLDQLNELGSELNAPIIQGSTRTKEREALFDAFRRGEVFTLVVSKVANFSIDLPEAAVAVQVS
GTFGSRQEEAQRLGRLLRPKADGGGAIFYSVVARDSLDAEYAAHRQRFLAEQGYSYIIRDADDLLGPAI

Sequences:

>Translated_549_residues
MTDGPLIVQSDKTVLLEVNHKLADAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAEQVVDTLISHARYAVPQ
PLLVDIVDTMARYGRLQLVKNPAHGLTLVSLDRTVLEEVLHNKKIAPMVGGRIDDDTVVVHPSERGRIKQLLLKIGWPAE
DLAGYVDGEAHPIILHQDGWQLRDYQRLAADSFWSGGSGVVVLPCGAGKTLVGAAAMAKTGATTLILVTNIVVARQWKRE
LITHTSLTEDEIGEYSGERKEIRPVTISTYQMITHRTKGEYRHLELFNSRDWGLIIYDEVHLLPAPVFRMTADLQSKRRL
GLTATLIREDGREGDVFSLIGPKRYDTPWKDLEEQGWIAPAKCVEVRVTLTNNERMTYATAEPEERYRVCSTAHSKIAVV
KSVLSRHPGEQTLVIGAYLDQLNELGSELNAPIIQGSTRTKEREALFDAFRRGEVFTLVVSKVANFSIDLPEAAVAVQVS
GTFGSRQEEAQRLGRLLRPKADGGGAIFYSVVARDSLDAEYAAHRQRFLAEQGYSYIIRDADDLLGPAI
>Mature_548_residues
TDGPLIVQSDKTVLLEVNHKLADAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAEQVVDTLISHARYAVPQP
LLVDIVDTMARYGRLQLVKNPAHGLTLVSLDRTVLEEVLHNKKIAPMVGGRIDDDTVVVHPSERGRIKQLLLKIGWPAED
LAGYVDGEAHPIILHQDGWQLRDYQRLAADSFWSGGSGVVVLPCGAGKTLVGAAAMAKTGATTLILVTNIVVARQWKREL
ITHTSLTEDEIGEYSGERKEIRPVTISTYQMITHRTKGEYRHLELFNSRDWGLIIYDEVHLLPAPVFRMTADLQSKRRLG
LTATLIREDGREGDVFSLIGPKRYDTPWKDLEEQGWIAPAKCVEVRVTLTNNERMTYATAEPEERYRVCSTAHSKIAVVK
SVLSRHPGEQTLVIGAYLDQLNELGSELNAPIIQGSTRTKEREALFDAFRRGEVFTLVVSKVANFSIDLPEAAVAVQVSG
TFGSRQEEAQRLGRLLRPKADGGGAIFYSVVARDSLDAEYAAHRQRFLAEQGYSYIIRDADDLLGPAI

Specific function: Unknown

COG id: COG1061

COG function: function code KL; DNA or RNA helicases of superfamily II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557563, Length=375, Percent_Identity=36.5333333333333, Blast_Score=236, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17556358, Length=379, Percent_Identity=34.8284960422164, Blast_Score=224, Evalue=7e-59,
Organism=Saccharomyces cerevisiae, GI6322048, Length=605, Percent_Identity=28.4297520661157, Blast_Score=253, Evalue=5e-68,
Organism=Drosophila melanogaster, GI221331068, Length=375, Percent_Identity=36.5333333333333, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI24662247, Length=375, Percent_Identity=36.5333333333333, Blast_Score=238, Evalue=7e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 60878; Mature: 60747

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDGPLIVQSDKTVLLEVNHKLADAARAAIAPFAELERAPEHVHTYRITPLALWNARAAG
CCCCCEEEECCCEEEEEECCHHHHHHHHHHCCHHHHHCCHHHHHEEEECEEEEECCCCCC
HDAEQVVDTLISHARYAVPQPLLVDIVDTMARYGRLQLVKNPAHGLTLVSLDRTVLEEVL
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHHHHHHH
HNKKIAPMVGGRIDDDTVVVHPSERGRIKQLLLKIGWPAEDLAGYVDGEAHPIILHQDGW
CCCCCCHHCCCCCCCCEEEECCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCC
QLRDYQRLAADSFWSGGSGVVVLPCGAGKTLVGAAAMAKTGATTLILVTNIVVARQWKRE
CHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHH
LITHTSLTEDEIGEYSGERKEIRPVTISTYQMITHRTKGEYRHLELFNSRDWGLIIYDEV
HHHHCCCCHHHHHHCCCCCCEECCEEEEHHHHHHHCCCCCEEEEEEECCCCCCEEEEECC
HLLPAPVFRMTADLQSKRRLGLTATLIREDGREGDVFSLIGPKRYDTPWKDLEEQGWIAP
CCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCCCCCCCHHHHHHCCCCCC
AKCVEVRVTLTNNERMTYATAEPEERYRVCSTAHSKIAVVKSVLSRHPGEQTLVIGAYLD
CEEEEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
QLNELGSELNAPIIQGSTRTKEREALFDAFRRGEVFTLVVSKVANFSIDLPEAAVAVQVS
HHHHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCCCCEEEEEEE
GTFGSRQEEAQRLGRLLRPKADGGGAIFYSVVARDSLDAEYAAHRQRFLAEQGYSYIIRD
CCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEC
ADDLLGPAI
CHHHCCCCC
>Mature Secondary Structure 
TDGPLIVQSDKTVLLEVNHKLADAARAAIAPFAELERAPEHVHTYRITPLALWNARAAG
CCCCEEEECCCEEEEEECCHHHHHHHHHHCCHHHHHCCHHHHHEEEECEEEEECCCCCC
HDAEQVVDTLISHARYAVPQPLLVDIVDTMARYGRLQLVKNPAHGLTLVSLDRTVLEEVL
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHHHHHHH
HNKKIAPMVGGRIDDDTVVVHPSERGRIKQLLLKIGWPAEDLAGYVDGEAHPIILHQDGW
CCCCCCHHCCCCCCCCEEEECCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCC
QLRDYQRLAADSFWSGGSGVVVLPCGAGKTLVGAAAMAKTGATTLILVTNIVVARQWKRE
CHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHH
LITHTSLTEDEIGEYSGERKEIRPVTISTYQMITHRTKGEYRHLELFNSRDWGLIIYDEV
HHHHCCCCHHHHHHCCCCCCEECCEEEEHHHHHHHCCCCCEEEEEEECCCCCCEEEEECC
HLLPAPVFRMTADLQSKRRLGLTATLIREDGREGDVFSLIGPKRYDTPWKDLEEQGWIAP
CCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCCCCCCCHHHHHHCCCCCC
AKCVEVRVTLTNNERMTYATAEPEERYRVCSTAHSKIAVVKSVLSRHPGEQTLVIGAYLD
CEEEEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
QLNELGSELNAPIIQGSTRTKEREALFDAFRRGEVFTLVVSKVANFSIDLPEAAVAVQVS
HHHHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCCCCEEEEEEE
GTFGSRQEEAQRLGRLLRPKADGGGAIFYSVVARDSLDAEYAAHRQRFLAEQGYSYIIRD
CCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEC
ADDLLGPAI
CHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA