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The map label for this gene is pdxH [H]

Identifier: 221230620

GI number: 221230620

Start: 2533083

End: 2533703

Strand: Reverse

Name: pdxH [H]

Synonym: MLBr_02131

Alternate gene names: 221230620

Gene position: 2533703-2533083 (Counterclockwise)

Preceding gene: 221230621

Following gene: 221230619

Centisome position: 77.53

GC content: 60.06

Gene sequence:

>621_bases
GTGGAGTACGGCTCCGTCGAGAAGGACGGCAGCCCCGATCTCGACACGGATTGGCTATATGATGGTTGGCTTACGCTGTT
CTGCAAGTGGATTGACGACGCCGAGCGCGCCGGAGTTGCCGAGCCCAATGCCATGGTGCTGGCAACCGTGGCCAACGGCA
GGCCGGTGAGCCGATCGGTGTTGTGTAAGGGCGCCGATGAGGCAGGAATTATTTTCTTCACCAATTATGATTCTGATAAG
GGCGACGACCTGGCAGCCACGCCTTATGCTTCGGTGACTTTCCCATGGTATCAGCTGGGGCGGCAGGTGCATATTCGCGG
CCCAGTGAGCACGGTCGACCCGCAGGTTAGCGAGGATTACTGGTCCAAACGGCCGCGTGGCTCGCAACTGGGGGCATGGG
CGTCGCATCAGTCGCGGCCGATCGCCTCGAGGACGGCGTTACTTGATCAGCTGCTAGAAGTAACCGTGCGCTTTGCTGAT
TCAGAGCTCATCCCGTTGCCGCCGAATTGGGGCGGATACCTCATTGTGCCCGAGGTGGTGGAATTCTGGCAGGGCCGGGA
AAACCGGGTGCACAACAGGATTCGGGTGACAGGCGGGTGTATCGAGCGTCTGCAGCCTTAA

Upstream 100 bases:

>100_bases
TCCCACCTGTCCCCGGGCCGATGTTACTGTCCAGTAACACCCTGCGGGTAGTGTTGGCGCGGTGGCAGGACCAGACGACC
AGCATCTGTCGGGTATGCGG

Downstream 100 bases:

>100_bases
CTAGGTGAGGATGTGCGTCGGGTAATGGCATCAGGAAGTGATGGGCGATGGTTAATCGCCTCGCTAGCGCCGGCATTGAT
TAGCTACCGGGCGCTGAGGG

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MEYGSVEKDGSPDLDTDWLYDGWLTLFCKWIDDAERAGVAEPNAMVLATVANGRPVSRSVLCKGADEAGIIFFTNYDSDK
GDDLAATPYASVTFPWYQLGRQVHIRGPVSTVDPQVSEDYWSKRPRGSQLGAWASHQSRPIASRTALLDQLLEVTVRFAD
SELIPLPPNWGGYLIVPEVVEFWQGRENRVHNRIRVTGGCIERLQP

Sequences:

>Translated_206_residues
MEYGSVEKDGSPDLDTDWLYDGWLTLFCKWIDDAERAGVAEPNAMVLATVANGRPVSRSVLCKGADEAGIIFFTNYDSDK
GDDLAATPYASVTFPWYQLGRQVHIRGPVSTVDPQVSEDYWSKRPRGSQLGAWASHQSRPIASRTALLDQLLEVTVRFAD
SELIPLPPNWGGYLIVPEVVEFWQGRENRVHNRIRVTGGCIERLQP
>Mature_206_residues
MEYGSVEKDGSPDLDTDWLYDGWLTLFCKWIDDAERAGVAEPNAMVLATVANGRPVSRSVLCKGADEAGIIFFTNYDSDK
GDDLAATPYASVTFPWYQLGRQVHIRGPVSTVDPQVSEDYWSKRPRGSQLGAWASHQSRPIASRTALLDQLLEVTVRFAD
SELIPLPPNWGGYLIVPEVVEFWQGRENRVHNRIRVTGGCIERLQP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=170, Percent_Identity=42.9411764705882, Blast_Score=145, Evalue=3e-35,
Organism=Escherichia coli, GI1787926, Length=172, Percent_Identity=43.0232558139535, Blast_Score=146, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17553712, Length=158, Percent_Identity=38.6075949367089, Blast_Score=113, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6319509, Length=185, Percent_Identity=40.5405405405405, Blast_Score=134, Evalue=9e-33,
Organism=Drosophila melanogaster, GI45551845, Length=182, Percent_Identity=43.4065934065934, Blast_Score=144, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24644901, Length=182, Percent_Identity=43.4065934065934, Blast_Score=144, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24644903, Length=172, Percent_Identity=29.6511627906977, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 23024; Mature: 23024

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYGSVEKDGSPDLDTDWLYDGWLTLFCKWIDDAERAGVAEPNAMVLATVANGRPVSRSV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHE
LCKGADEAGIIFFTNYDSDKGDDLAATPYASVTFPWYQLGRQVHIRGPVSTVDPQVSEDY
EECCCCCCCEEEEECCCCCCCCCEECCCCCEEECCHHHCCCEEEEECCCCCCCCCCCHHH
WSKRPRGSQLGAWASHQSRPIASRTALLDQLLEVTVRFADSELIPLPPNWGGYLIVPEVV
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEHHHHH
EFWQGRENRVHNRIRVTGGCIERLQP
HHHCCCCHHCCCEEEECCHHHHHCCC
>Mature Secondary Structure
MEYGSVEKDGSPDLDTDWLYDGWLTLFCKWIDDAERAGVAEPNAMVLATVANGRPVSRSV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHE
LCKGADEAGIIFFTNYDSDKGDDLAATPYASVTFPWYQLGRQVHIRGPVSTVDPQVSEDY
EECCCCCCCEEEEECCCCCCCCCEECCCCCEEECCHHHCCCEEEEECCCCCCCCCCCHHH
WSKRPRGSQLGAWASHQSRPIASRTALLDQLLEVTVRFADSELIPLPPNWGGYLIVPEVV
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEHHHHH
EFWQGRENRVHNRIRVTGGCIERLQP
HHHCCCCHHCCCEEEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]