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The map label for this gene is blaI [H]

Identifier: 221230589

GI number: 221230589

Start: 2450581

End: 2451009

Strand: Direct

Name: blaI [H]

Synonym: MLBr_02063

Alternate gene names: 221230589

Gene position: 2450581-2451009 (Clockwise)

Preceding gene: 221230588

Following gene: 221230590

Centisome position: 74.99

GC content: 60.84

Gene sequence:

>429_bases
ATGGCCAAGCTGACGCGGCTGGGGGATTTAGAACGTGCCGTGATGGATCATTTGTGGTCCAGACAAGAACCCCAAACAGT
TCGTCAGGTCCACGAAGCGTTGTCGGCGCGACGCGACCTCGCCTACACGACTGTGATGACCGTGCTGCAGCGATTGGCTA
AGAAGAATCTGGTCTCGCAGATTCGTAACAACCGGGCCCACCGATACGCGCCGGTGCATGGCCGGGACGAACTGGTGGCT
GGCTTAATGGTCGACGCGCTGGACCAAGCCGAGGATTCCGATAGCAGGCAAGCCGCGCTTGTGCACTTCGTCGAGCGGGT
CGGGGCCGACGAGGCGGACGCGCTGCGACGCGCACTTGCAGAACTGGAAACACATCAACGCCATGTCCGTCATCTGGTGG
CACTCCAGCGGACAACTGAGGGAGACTAG

Upstream 100 bases:

>100_bases
CCGACTCGGCTACCGCCGGGCCGACGGCAACCGACTTGGATACGACAATCGGTAGTAATCCGGAGTAAGCTGGCTTCAAC
GCTCAGGAGATGAACGAACT

Downstream 100 bases:

>100_bases
CAGCGTGTCCGCACTGGCCTTTACCATCCTCGCGGTGCTGCTGGTTGGCCCCACACCGACCTTAGTAGCACGTTCGACAT
GGCCGTTGCGCGCTCCACGC

Product: putative regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MAKLTRLGDLERAVMDHLWSRQEPQTVRQVHEALSARRDLAYTTVMTVLQRLAKKNLVSQIRNNRAHRYAPVHGRDELVA
GLMVDALDQAEDSDSRQAALVHFVERVGADEADALRRALAELETHQRHVRHLVALQRTTEGD

Sequences:

>Translated_142_residues
MAKLTRLGDLERAVMDHLWSRQEPQTVRQVHEALSARRDLAYTTVMTVLQRLAKKNLVSQIRNNRAHRYAPVHGRDELVA
GLMVDALDQAEDSDSRQAALVHFVERVGADEADALRRALAELETHQRHVRHLVALQRTTEGD
>Mature_141_residues
AKLTRLGDLERAVMDHLWSRQEPQTVRQVHEALSARRDLAYTTVMTVLQRLAKKNLVSQIRNNRAHRYAPVHGRDELVAG
LMVDALDQAEDSDSRQAALVHFVERVGADEADALRRALAELETHQRHVRHLVALQRTTEGD

Specific function: Transcription regulator that binds to an inverted DNA repeat with the consensus sequence 5'-TAC[GT]AC-NNNNN-GT[AC]GTA-3' and regulates genes involved in antibiotic transport, detoxification and cell wall function. Also regulates its own transcription. Bin

COG id: COG3682

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BlaI transcriptional regulatory family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005650
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03965 Pencillinase_R [H]

EC number: NA

Molecular weight: Translated: 16161; Mature: 16029

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLTRLGDLERAVMDHLWSRQEPQTVRQVHEALSARRDLAYTTVMTVLQRLAKKNLVSQ
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRNNRAHRYAPVHGRDELVAGLMVDALDQAEDSDSRQAALVHFVERVGADEADALRRALA
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
ELETHQRHVRHLVALQRTTEGD
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKLTRLGDLERAVMDHLWSRQEPQTVRQVHEALSARRDLAYTTVMTVLQRLAKKNLVSQ
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRNNRAHRYAPVHGRDELVAGLMVDALDQAEDSDSRQAALVHFVERVGADEADALRRALA
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
ELETHQRHVRHLVALQRTTEGD
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]