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The map label for this gene is oxyR

Identifier: 221230578

GI number: 221230578

Start: 2431909

End: 2432844

Strand: Reverse

Name: oxyR

Synonym: MLBr_02041

Alternate gene names: 221230578

Gene position: 2432844-2431909 (Counterclockwise)

Preceding gene: 221230580

Following gene: 221230577

Centisome position: 74.44

GC content: 61.22

Gene sequence:

>936_bases
ATGAGTGATAAGAGTTATCAGCCCACCATCGCTGGGCTTCGCGCCTTTGTCGCAGTGGTTGAGAAGGGTCACTTCAGCGC
CGCGGCAAGCTTTCTCGGCGTGAGGCAGTCGACGTTGTCGCAGGCGTTAGCGGCGCTGGAGTCCGGACTTGGTGTGCAGC
TGATCGAACGTTCTACCCGACGGGTTTTCGTGACGACGCAGGGTAGGCACCTACTACCACGCGCCCAGGCTGCGATCGAG
GCGATGGACGCGTTCACCGCAGCAGCTGCCGGCGAATCGGATCCGCTGCGAGGTGGCATGCGCCTTGGACTGATTCCCAC
CGTGGCGCCGTATGTGCTGCCGACGATGTTGACTGGACTCACCCATCGGCTGCCGACGTTAACCTTGCGAGTGGTCGAGG
ACCAGACAGAGCACCTGCTGACCGCGTTGCGTGAGGGGGCATTAGATGCTGCAATGATCGCCTTACCGGTTGAAACTGCC
GGGATTGCCGAGATACCAATCTATGATGAGGATTTTGTCCTCGCGCTACCCCCAGGGCATCCGCTTTCCGGCAAGCGCCG
GGTGCCGACAACGGCACTGGCGCAATTGCCGCTGTTGTTGTTGGATGAGGGTCATTGCTTGCGAGACCAGACCCTCGATA
TCTGCCGGAAATCGGGAGTGCAGGCCGAGCTGGCTAACACCCGCGCAGCGTCGTTGGCGACCGCTGTGCAATGCGTGACC
GGCGGGTTGGGGGTGACGCTGCTCCCGCAGAGTGCTGCGCCTGTCGAGTCGGTGCGTAGCAAACTTGGACTTGCCCAGTT
CGCTGCCCCCTGCCCCGGGAGACGGATTGGTCTGGCTTTCCGCTCCGCTAGCGGTCGCAGTGCTTCCTATCGGCAGATTG
CCAAGATCATTGGTGAGTTGATTAGTACAGAGCATCATGTGCGGCTGGTCGCATAG

Upstream 100 bases:

>100_bases
TTGTTTGGATTGATTCAAAATCAGATTTTTACACTATCCTTCAAGGTTGCCGTGAGTTTGGTCTGAAGTAAAGGTGATAT
ATCACACTATACTTATCGGT

Downstream 100 bases:

>100_bases
CAGTTCGGGTACCGGCAAACCAGAGATCGTCCTCATGCCCATGCCAGCGACGGTAAGCTCGCCCTAGTAGGAAAAGATAA
TCGCCCTGCTTATGCGTGCT

Product: putative LysR-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIE
AMDAFTAAAAGESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVVEDQTEHLLTALREGALDAAMIALPVETA
GIAEIPIYDEDFVLALPPGHPLSGKRRVPTTALAQLPLLLLDEGHCLRDQTLDICRKSGVQAELANTRAASLATAVQCVT
GGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSASYRQIAKIIGELISTEHHVRLVA

Sequences:

>Translated_311_residues
MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIE
AMDAFTAAAAGESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVVEDQTEHLLTALREGALDAAMIALPVETA
GIAEIPIYDEDFVLALPPGHPLSGKRRVPTTALAQLPLLLLDEGHCLRDQTLDICRKSGVQAELANTRAASLATAVQCVT
GGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSASYRQIAKIIGELISTEHHVRLVA
>Mature_310_residues
SDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEA
MDAFTAAAAGESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVVEDQTEHLLTALREGALDAAMIALPVETAG
IAEIPIYDEDFVLALPPGHPLSGKRRVPTTALAQLPLLLLDEGHCLRDQTLDICRKSGVQAELANTRAASLATAVQCVTG
GLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSASYRQIAKIIGELISTEHHVRLVA

Specific function: Required for the induction the katG gene for catalase. Involved in the response to hydrogen peroxide

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790399, Length=289, Percent_Identity=37.3702422145329, Blast_Score=184, Evalue=4e-48,
Organism=Escherichia coli, GI157672245, Length=277, Percent_Identity=28.8808664259928, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI145693105, Length=283, Percent_Identity=26.8551236749117, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1787879, Length=248, Percent_Identity=28.6290322580645, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788481, Length=270, Percent_Identity=28.5185185185185, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787530, Length=243, Percent_Identity=26.7489711934156, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788887, Length=241, Percent_Identity=28.2157676348548, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788748, Length=247, Percent_Identity=24.2914979757085, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=187, Percent_Identity=25.668449197861, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787806, Length=240, Percent_Identity=25.4166666666667, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789204, Length=177, Percent_Identity=29.3785310734463, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=28.4552845528455, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786401, Length=155, Percent_Identity=30.9677419354839, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082132, Length=254, Percent_Identity=25.9842519685039, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367136, Length=256, Percent_Identity=24.609375, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790262, Length=245, Percent_Identity=26.1224489795918, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87081904, Length=216, Percent_Identity=25.9259259259259, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1789506, Length=272, Percent_Identity=23.1617647058824, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXYR_MYCLE (P52678)

Other databases:

- EMBL:   L01095
- EMBL:   AL583924
- PIR:   D87164
- RefSeq:   NP_302364.1
- ProteinModelPortal:   P52678
- SMR:   P52678
- EnsemblBacteria:   EBMYCT00000028628
- GeneID:   909008
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML2041
- NMPDR:   fig|272631.1.peg.1236
- Leproma:   ML2041
- GeneTree:   EBGT00050000015801
- HOGENOM:   HBG685425
- OMA:   SNKEYRP
- ProtClustDB:   CLSK557030
- BioCyc:   MLEP272631:ML2041-MONOMER
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00039

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 32841; Mature: 32709

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGLGVQLIERSTR
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCC
RVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGMRLGLIPTVAPYVLPTMLTGL
EEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHH
THRLPTLTLRVVEDQTEHLLTALREGALDAAMIALPVETAGIAEIPIYDEDFVLALPPGH
HHHCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCCCCEEEECCCCC
PLSGKRRVPTTALAQLPLLLLDEGHCLRDQTLDICRKSGVQAELANTRAASLATAVQCVT
CCCCCCCCCHHHHHHCCHHEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSASYRQIAKIIGEL
CCCCEEECCCCCCCHHHHHHHHCHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
ISTEHHVRLVA
HCCCCCEEEEC
>Mature Secondary Structure 
SDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGLGVQLIERSTR
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCC
RVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGMRLGLIPTVAPYVLPTMLTGL
EEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHH
THRLPTLTLRVVEDQTEHLLTALREGALDAAMIALPVETAGIAEIPIYDEDFVLALPPGH
HHHCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCCCCEEEECCCCC
PLSGKRRVPTTALAQLPLLLLDEGHCLRDQTLDICRKSGVQAELANTRAASLATAVQCVT
CCCCCCCCCHHHHHHCCHHEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSASYRQIAKIIGEL
CCCCEEECCCCCCCHHHHHHHHCHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
ISTEHHVRLVA
HCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8006590; 11234002