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The map label for this gene is nusG

Identifier: 221230497

GI number: 221230497

Start: 2291529

End: 2292215

Strand: Reverse

Name: nusG

Synonym: MLBr_01906

Alternate gene names: 221230497

Gene position: 2292215-2291529 (Counterclockwise)

Preceding gene: 221230498

Following gene: 221230496

Centisome position: 70.14

GC content: 61.43

Gene sequence:

>687_bases
GTGCAAGAGGCCGGTATCGACGAGTTCGCCGCGGGTGGCGGTCACGTGGAGCCGGCTGCAGAGGTCGACCCGGCCGCCGC
GCTCAAGGCAGAGCTGCGTAGCAAGCCGGGCGACTGGTATGTCATCCACTCCTACGCGGGGTATGAGAACAAGGTGAAAG
CCAACCTCGAAACCCGTGTGCAGAACCTAGACGTCGGCGACTGCATCTTCCAGGTGGAGGTGCCCACCGAGGAGGTCACC
GAGATCAAGAATGGCCAGCGCAGGCTGGTTAACCGCAAGGTGCTACCTGGCTACATCCTGGTGCGGATGGATTTGACCGA
CGATTCGTGGGCGGCGGTGCGCAACACTCCGGGGGTCACCGGATTCGTCGGTGCAACGTCGCGTCCGTCGGCGCTTGCGC
TTGACGACGTGGTGAAGTTCTTGTTGCCGTCGGGGTCGGCAAAGAAGGACGCCAAGGGTGCAGTCAGTACCGCCGCTGCC
GCCGAGGCGGGTGGGTTGGAACGTTCGATTATCGAGGTCGATTACGAGGTGGGCGAATCGGTAACGGTCATGGACGGACC
GTTTGCGACGTTGCCAGCTACGATTAGCGAAGTCAACGCCGAGCAGCAAAAGCTCAAGGTGCTGGTTTCGATCTTCGGTC
GCGAAACCCCGGTGGAGCTGACCTTCAGCCAAGTCTCGAAGATTTAA

Upstream 100 bases:

>100_bases
TGGTGTTGTTGGTGTTCGGCTGAGGCTCGAAAGTGATTAGAGAGGACTGAAAACCGTGACTACCTTCGACGGTGATGCGT
CTTCAGGTGAGGCGGTTGAC

Downstream 100 bases:

>100_bases
CCCCCGAGGAAGGAAGAACGAAACCCAATGGCCACGAAAAAGAAAGTCGCCGGGCTGATCAAGCTTCAGATTCAGGCGGG
GCAGGCCAACCCTGCTCCGC

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MQEAGIDEFAAGGGHVEPAAEVDPAAALKAELRSKPGDWYVIHSYAGYENKVKANLETRVQNLDVGDCIFQVEVPTEEVT
EIKNGQRRLVNRKVLPGYILVRMDLTDDSWAAVRNTPGVTGFVGATSRPSALALDDVVKFLLPSGSAKKDAKGAVSTAAA
AEAGGLERSIIEVDYEVGESVTVMDGPFATLPATISEVNAEQQKLKVLVSIFGRETPVELTFSQVSKI

Sequences:

>Translated_228_residues
MQEAGIDEFAAGGGHVEPAAEVDPAAALKAELRSKPGDWYVIHSYAGYENKVKANLETRVQNLDVGDCIFQVEVPTEEVT
EIKNGQRRLVNRKVLPGYILVRMDLTDDSWAAVRNTPGVTGFVGATSRPSALALDDVVKFLLPSGSAKKDAKGAVSTAAA
AEAGGLERSIIEVDYEVGESVTVMDGPFATLPATISEVNAEQQKLKVLVSIFGRETPVELTFSQVSKI
>Mature_228_residues
MQEAGIDEFAAGGGHVEPAAEVDPAAALKAELRSKPGDWYVIHSYAGYENKVKANLETRVQNLDVGDCIFQVEVPTEEVT
EIKNGQRRLVNRKVLPGYILVRMDLTDDSWAAVRNTPGVTGFVGATSRPSALALDDVVKFLLPSGSAKKDAKGAVSTAAA
AEAGGLERSIIEVDYEVGESVTVMDGPFATLPATISEVNAEQQKLKVLVSIFGRETPVELTFSQVSKI

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nusG family

Homologues:

Organism=Escherichia coli, GI1790414, Length=193, Percent_Identity=40.4145077720207, Blast_Score=140, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUSG_MYCLE (Q9CBK0)

Other databases:

- EMBL:   AL583923
- PIR:   D87147
- RefSeq:   NP_302283.1
- ProteinModelPortal:   Q9CBK0
- SMR:   Q9CBK0
- EnsemblBacteria:   EBMYCT00000028324
- GeneID:   910584
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML1906
- NMPDR:   fig|272631.1.peg.1155
- Leproma:   ML1906
- GeneTree:   EBGT00050000017483
- HOGENOM:   HBG751162
- OMA:   ENRVKAN
- ProtClustDB:   PRK05609
- BioCyc:   MLEP272631:ML1906-MONOMER
- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.30.30.30
- Gene3D:   G3DSA:3.30.70.940
- PRINTS:   PR00338
- SMART:   SM00739
- SMART:   SM00738
- TIGRFAMs:   TIGR00922

Pfam domain/function: PF02357 NusG; SSF82679 Transcrpt_antiterm_NusG_N; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 24347; Mature: 24347

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEAGIDEFAAGGGHVEPAAEVDPAAALKAELRSKPGDWYVIHSYAGYENKVKANLETRV
CCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCEEECCHHHHH
QNLDVGDCIFQVEVPTEEVTEIKNGQRRLVNRKVLPGYILVRMDLTDDSWAAVRNTPGVT
HCCCCCCEEEEEECCHHHHHHHHCCHHHHHCCCCCCCEEEEEEECCCCCCHHHCCCCCCE
GFVGATSRPSALALDDVVKFLLPSGSAKKDAKGAVSTAAAAEAGGLERSIIEVDYEVGES
EEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCE
VTVMDGPFATLPATISEVNAEQQKLKVLVSIFGRETPVELTFSQVSKI
EEEECCCCHHCCHHHHHHCHHHHHHHHHHHHHCCCCCEEEEHHHHHCC
>Mature Secondary Structure
MQEAGIDEFAAGGGHVEPAAEVDPAAALKAELRSKPGDWYVIHSYAGYENKVKANLETRV
CCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCEEECCHHHHH
QNLDVGDCIFQVEVPTEEVTEIKNGQRRLVNRKVLPGYILVRMDLTDDSWAAVRNTPGVT
HCCCCCCEEEEEECCHHHHHHHHCCHHHHHCCCCCCCEEEEEEECCCCCCHHHCCCCCCE
GFVGATSRPSALALDDVVKFLLPSGSAKKDAKGAVSTAAAAEAGGLERSIIEVDYEVGES
EEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCE
VTVMDGPFATLPATISEVNAEQQKLKVLVSIFGRETPVELTFSQVSKI
EEEECCCCHHCCHHHHHHCHHHHHHHHHHHHHCCCCCEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002