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The map label for this gene is rpoB [H]

Identifier: 221230487

GI number: 221230487

Start: 2273194

End: 2276730

Strand: Reverse

Name: rpoB [H]

Synonym: MLBr_01891

Alternate gene names: 221230487

Gene position: 2276730-2273194 (Counterclockwise)

Preceding gene: 221230488

Following gene: 221230486

Centisome position: 69.67

GC content: 60.96

Gene sequence:

>3537_bases
GTGCTGGAAGGATGCATCTTGCCAGATTTCGGCCAGAGCAAGACAGACGTTAGTCCTAGCCAGAGTCGCCCCCAAAGTTC
GCCCAACAACTCCGTGCCCGGCGCGCCCAACCGAATTTCATTTGCCAAGCTCCGCGAACCGCTTGAGGTTCCGGGGCTAC
TTGATGTGCAGACTGATTCATTTGAGTGGTTGATCGGATCGCCGTGCTGGCGTGCAGCGGCCGCAAGCCGCGGCGATCTC
AAGCCGGTGGGTGGTCTCGAAGAGGTGCTCTACGAGCTGTCGCCGATCGAGGATTTCTCCGGCTCAATGTCATTGTCTTT
CTCCGATCCCCGTTTTGACGAAGTCAAGGCGCCCGTCGAAGAGTGCAAAGACAAGGACATGACGTACGCGGCCCCGCTGT
TCGTCACGGCCGAGTTCATCAACAACAACACCGGGGAGATCAAGAGCCAGACGGTGTTTATGGGCGACTTCCCTATGATG
ACTGAGAAGGGAACCTTCATCATCAACGGGACCGAGCGTGTCGTCGTTAGCCAGCTGGTGCGCTCCCCTGGAGTATACTT
CGACGAGACGATCGACAAGTCCACAGAAAAGACGCTGCATAGTGTCAAGGTGATTCCCAGCCGCGGTGCCTGGTTGGAAT
TCGATGTCGATAAACGCGACACCGTCGGTGTCCGCATTGACCGGAAGCGCCGGCAACCCGTCACGGTGCTTCTCAAAGCG
CTAGGTTGGACCAGTGAGCAGATCACCGAGCGTTTCGGTTTCTCCGAGATCATGCGCTCGACGCTGGAGAAGGACAACAC
AGTTGGCACCGACGAGGCGCTGCTAGACATCTATCGTAAGTTGCGCCCAGGTGAGCCGCCGACTAAGGAGTCCGCGCAGA
CGCTGTTGGAGAACCTGTTCTTCAAGGAGAAACGCTACGACCTGGCCAGGGTTGGTCGTTACAAGGTCAACAAGAAGCTC
GGGTTGCACGCCGGTGAGTTGATCACGTCGTCCACGCTGACCGAAGAGGATGTCGTCGCCACCATAGAGTACCTGGTTCG
TCTGCATGAGGGTCAGTCGACAATGACTGTCCCAGGTGGGGTAGAAGTGCCAGTGGAAACTGACGATATCGACCACTTCG
GCAACCGCCGGCTGCGCACGGTCGGCGAATTGATCCAGAACCAGATCCGGGTCGGTATGTCGCGGATGGAGCGGGTGGTC
CGGGAGCGGATGACCACCCAGGACGTCGAGGCGATCACGCCGCAGACGCTGATCAATATCCGTCCGGTGGTCGCCGCTAT
CAAGGAATTCTTCGGCACCAGCCAGCTGTCGCAGTTCATGGATCAGAACAACCCTCTGTCGGGCCTGACCCACAAGCGCC
GGCTGTCGGCGCTGGGCCCGGGTGGTTTGTCGCGTGAGCGTGCCGGGCTAGAGGTCCGTGACGTGCACCCTTCGCACTAC
GGCCGGATGTGCCCGATCGAGACTCCGGAGGGCCCGAACATAGGTCTGATCGGTTCATTGTCGGTGTACGCGCGGGTCAA
CCCCTTCGGGTTCATCGAAACACCGTACCGCAAAGTGGTTGACGGTGTGGTCAGCGACGAGATCGAATACTTGACCGCTG
ACGAGGAAGACCGCCATGTCGTGGCGCAGGCCAACTCGCCGATCGACGAGGCCGGCCGCTTCCTCGAGCCGCGCGTGTTG
GTGCGCCGCAAGGCGGGCGAGGTGGAGTACGTGGCCTCGTCCGAGGTGGATTACATGGATGTCTCGCCACGCCAGATGGT
GTCGGTGGCCACAGCGATGATTCCGTTCCTTGAGCACGACGACGCCAACCGTGCCCTGATGGGCGCTAACATGCAGCGCC
AAGCGGTTCCGTTGGTGCGCAGCGAAGCACCGTTGGTGGGTACCGGTATGGAGTTGCGCGCGGCCATCGACGCTGGCCAC
GTCGTCGTTGCGGAGAAGTCCGGGGTGATCGAGGAGGTTTCCGCCGACTACATCACCGTGATGGCCGATGACGGCACCCG
GCGGACTTATCGGATGCGTAAGTTCGCGCGCTCCAACCACGGCACCTGCGCCAACCAGTCCCCGATCGTGGATGCGGGGG
ATCGGGTCGAGGCCGGCCAAGTGATTGCTGACGGTCCGTGCACTGAGAACGGCGAGATGGCGTTGGGCAAGAACTTGCTG
GTGGCGATCATGCCGTGGGAGGGTCACAACTACGAGGATGCGATCATCCTGTCTAACCGACTGGTCGAAGAGGACGTGCT
TACTTCGATTCACATTGAGGAGCATGAGATCGACGCCCGTGACACCAAGCTGGGTGCTGAGGAGATCACCCGGGACATTC
CCAACGTCTCCGATGAGGTGCTAGCCGACTTGGACGAGCGGGGCATCGTGCGGATTGGCGCGGAGGTTCGTGACGGTGAT
ATCCTGGTTGGCAAGGTCACCCCGAAGGGGGAAACTGAGCTGACACCGGAAGAGCGGTTGCTGCGGGCGATCTTCGGCGA
AAAGGCCCGCGAGGTCCGTGACACGTCGCTGAAGGTGCCACACGGCGAATCCGGCAAGGTGATCGGCATTCGGGTGTTCT
CCCATGAGGATGACGACGAGCTGCCCGCCGGCGTCAACGAGCTGGTCCGTGTCTACGTAGCCCAGAAGCGCAAGATCTCT
GACGGTGACAAGCTGGCTGGGCGGCACGGCAACAAGGGCGTGATCGGCAAGATCCTGCCTGCCGAGGATATGCCGTTTCT
GCCAGACGGCACCCCGGTGGACATCATCCTCAACACTCACGGGGTGCCGCGGCGGATGAACGTCGGTCAGATCTTGGAAA
CCCACCTTGGGTGGGTAGCCAAGTCCGGCTGGAAGATCGACGTGGCCGGCGGTATACCGGATTGGGCGGTCAACTTGCCT
GAGGAGTTGTTGCACGCTGCGCCCAACCAGATCGTGTCGACCCCGGTGTTCGACGGCGCCAAGGAAGAGGAACTACAGGG
CCTGTTGTCCTCCACGTTGCCCAACCGCGACGGCGATGTGATGGTGGGCGGCGACGGCAAGGCGGTGCTCTTCGATGGGC
GCAGCGGTGAGCCGTTCCCTTATCCGGTGACGGTTGGCTACATGTACATCATGAAGCTGCACCACTTGGTGGACGACAAG
ATCCACGCCCGCTCCACCGGCCCGTACTCGATGATTACCCAGCAGCCGTTGGGTGGTAAGGCACAGTTCGGTGGCCAGCG
ATTCGGTGAGATGGAGTGCTGGGCCATGCAGGCCTACGGTGCGGCCTACACGCTGCAGGAGCTGTTGACCATCAAGTCCG
ACGACACCGTCGGTCGGGTCAAGGTTTACGAGGCTATCGTTAAGGGTGAGAACATCCCCGAGCCGGGCATCCCCGAGTCG
TTCAAGGTGCTGCTCAAGGAGTTACAGTCGCTGTGTCTCAACGTCGAGGTGCTGTCGTCCGACGGTGCGGCGATCGAGTT
GCGCGAAGGTGAGGATGAGGACCTCGAGCGGGCTGCGGCCAACCTCGGTATCAACTTGTCCCGCAACGAATCGGCGTCCA
TAGAAGATCTGGCTTAG

Upstream 100 bases:

>100_bases
GTGAGATCTGGGCCGGGTTGTTCGCCGGCCTAACTAACATGACTATCGCGGCGAACCGGCGTACACCAGTTTTCTGGAGT
TCACTGTTGAGCCGCACGAG

Downstream 100 bases:

>100_bases
CGAACTTGGCATTATCGTCACTAAACCCGCAAGGGGAAAGGGAGTTACGTGCTAGACGTCAACTTCTTCGATGAACTCCG
CATTGGCCTGGCTACCGCGG

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1178; Mature: 1178

Protein sequence:

>1178_residues
MLEGCILPDFGQSKTDVSPSQSRPQSSPNNSVPGAPNRISFAKLREPLEVPGLLDVQTDSFEWLIGSPCWRAAAASRGDL
KPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDEVKAPVEECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMM
TEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTEKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKA
LGWTSEQITERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKL
GLHAGELITSSTLTEEDVVATIEYLVRLHEGQSTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVV
RERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHY
GRMCPIETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIEYLTADEEDRHVVAQANSPIDEAGRFLEPRVL
VRRKAGEVEYVASSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGH
VVVAEKSGVIEEVSADYITVMADDGTRRTYRMRKFARSNHGTCANQSPIVDAGDRVEAGQVIADGPCTENGEMALGKNLL
VAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAEVRDGD
ILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSHEDDDELPAGVNELVRVYVAQKRKIS
DGDKLAGRHGNKGVIGKILPAEDMPFLPDGTPVDIILNTHGVPRRMNVGQILETHLGWVAKSGWKIDVAGGIPDWAVNLP
EELLHAAPNQIVSTPVFDGAKEEELQGLLSSTLPNRDGDVMVGGDGKAVLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDK
IHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPES
FKVLLKELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASIEDLA

Sequences:

>Translated_1178_residues
MLEGCILPDFGQSKTDVSPSQSRPQSSPNNSVPGAPNRISFAKLREPLEVPGLLDVQTDSFEWLIGSPCWRAAAASRGDL
KPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDEVKAPVEECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMM
TEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTEKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKA
LGWTSEQITERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKL
GLHAGELITSSTLTEEDVVATIEYLVRLHEGQSTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVV
RERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHY
GRMCPIETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIEYLTADEEDRHVVAQANSPIDEAGRFLEPRVL
VRRKAGEVEYVASSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGH
VVVAEKSGVIEEVSADYITVMADDGTRRTYRMRKFARSNHGTCANQSPIVDAGDRVEAGQVIADGPCTENGEMALGKNLL
VAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAEVRDGD
ILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSHEDDDELPAGVNELVRVYVAQKRKIS
DGDKLAGRHGNKGVIGKILPAEDMPFLPDGTPVDIILNTHGVPRRMNVGQILETHLGWVAKSGWKIDVAGGIPDWAVNLP
EELLHAAPNQIVSTPVFDGAKEEELQGLLSSTLPNRDGDVMVGGDGKAVLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDK
IHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPES
FKVLLKELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASIEDLA
>Mature_1178_residues
MLEGCILPDFGQSKTDVSPSQSRPQSSPNNSVPGAPNRISFAKLREPLEVPGLLDVQTDSFEWLIGSPCWRAAAASRGDL
KPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDEVKAPVEECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMM
TEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTEKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKA
LGWTSEQITERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKL
GLHAGELITSSTLTEEDVVATIEYLVRLHEGQSTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVV
RERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHY
GRMCPIETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIEYLTADEEDRHVVAQANSPIDEAGRFLEPRVL
VRRKAGEVEYVASSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGH
VVVAEKSGVIEEVSADYITVMADDGTRRTYRMRKFARSNHGTCANQSPIVDAGDRVEAGQVIADGPCTENGEMALGKNLL
VAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAEVRDGD
ILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSHEDDDELPAGVNELVRVYVAQKRKIS
DGDKLAGRHGNKGVIGKILPAEDMPFLPDGTPVDIILNTHGVPRRMNVGQILETHLGWVAKSGWKIDVAGGIPDWAVNLP
EELLHAAPNQIVSTPVFDGAKEEELQGLLSSTLPNRDGDVMVGGDGKAVLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDK
IHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPES
FKVLLKELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASIEDLA

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI4505941, Length=451, Percent_Identity=28.3813747228381, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI33469941, Length=736, Percent_Identity=24.0489130434783, Blast_Score=141, Evalue=4e-33,
Organism=Homo sapiens, GI212286172, Length=737, Percent_Identity=24.0162822252374, Blast_Score=141, Evalue=4e-33,
Organism=Homo sapiens, GI238908503, Length=441, Percent_Identity=28.3446712018141, Blast_Score=140, Evalue=7e-33,
Organism=Homo sapiens, GI238908505, Length=441, Percent_Identity=28.3446712018141, Blast_Score=140, Evalue=8e-33,
Organism=Escherichia coli, GI1790419, Length=603, Percent_Identity=58.0431177446103, Blast_Score=709, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=446, Percent_Identity=28.47533632287, Blast_Score=159, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI25144348, Length=435, Percent_Identity=27.816091954023, Blast_Score=149, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17506623, Length=221, Percent_Identity=31.6742081447964, Blast_Score=106, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6324725, Length=445, Percent_Identity=28.314606741573, Blast_Score=154, Evalue=8e-38,
Organism=Saccharomyces cerevisiae, GI6324781, Length=442, Percent_Identity=28.0542986425339, Blast_Score=144, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6325267, Length=400, Percent_Identity=27.25, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI17647877, Length=443, Percent_Identity=28.4424379232506, Blast_Score=148, Evalue=2e-35,
Organism=Drosophila melanogaster, GI17136444, Length=448, Percent_Identity=27.2321428571429, Blast_Score=146, Evalue=7e-35,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 129730; Mature: 129730

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEGCILPDFGQSKTDVSPSQSRPQSSPNNSVPGAPNRISFAKLREPLEVPGLLDVQTDS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEECCCC
FEWLIGSPCWRAAAASRGDLKPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDEVKAPVE
CCEEECCCHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHCCHH
ECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTFIINGTERVVVSQLV
HHCCCCCEEECHHEEEEEHHCCCCCCCEEEEEEECCCCCEECCCEEEECCCHHHHHHHHH
RSPGVYFDETIDKSTEKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKA
HCCCCEEHHHHCHHHHHHHHHEEEECCCCCEEEEECCCCCCCCEEECCCCCCHHHHHHHH
LGWTSEQITERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLF
HCCCHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
FKEKRYDLARVGRYKVNKKLGLHAGELITSSTLTEEDVVATIEYLVRLHEGQSTMTVPGG
HHHHHHHHHHHCHHEECCHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEECCCC
VEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTTQDVEAITPQTLINI
EECCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHY
HHHHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCHHHCCCEEEECCCCCC
GRMCPIETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIEYLTADEEDRHV
CCCCCCCCCCCCCEEEEECEEEEEEECCCCCCCCCHHHHHHHHHHCCHHEEECCCCCCEE
VAQANSPIDEAGRFLEPRVLVRRKAGEVEYVASSEVDYMDVSPRQMVSVATAMIPFLEHD
EEECCCCHHHHHHHCCCHHHHHHCCCCEEEEECCCCCEECCCHHHHHHHHHHHHHHHCCC
DANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGHVVVAEKSGVIEEVSADYITV
CCCCEEECCCCHHHCCCHHHCCCCEEECCCCEEEEECCCEEEEEECCCCHHHCCCCEEEE
MADDGTRRTYRMRKFARSNHGTCANQSPIVDAGDRVEAGQVIADGPCTENGEMALGKNLL
EECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEECCCEE
VAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEV
EEEECCCCCCCCCEEEECCHHHHHHHHHEEEEECCCCCCHHHCCCHHHHHHHCCCCCHHH
LADLDERGIVRIGAEVRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVP
HHCCCCCCEEEECCEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECC
HGESGKVIGIRVFSHEDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVIGKILP
CCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEECC
AEDMPFLPDGTPVDIILNTHGVPRRMNVGQILETHLGWVAKSGWKIDVAGGIPDWAVNLP
CCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHCCCH
EELLHAAPNQIVSTPVFDGAKEEELQGLLSSTLPNRDGDVMVGGDGKAVLFDGRSGEPFP
HHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCCCC
YPVTVGYMYIMKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYG
CCHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHHH
AAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVLSS
HHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEC
DGAAIELREGEDEDLERAAANLGINLSRNESASIEDLA
CCCEEEECCCCCHHHHHHHHHCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MLEGCILPDFGQSKTDVSPSQSRPQSSPNNSVPGAPNRISFAKLREPLEVPGLLDVQTDS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEECCCC
FEWLIGSPCWRAAAASRGDLKPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDEVKAPVE
CCEEECCCHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHCCHH
ECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTFIINGTERVVVSQLV
HHCCCCCEEECHHEEEEEHHCCCCCCCEEEEEEECCCCCEECCCEEEECCCHHHHHHHHH
RSPGVYFDETIDKSTEKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKA
HCCCCEEHHHHCHHHHHHHHHEEEECCCCCEEEEECCCCCCCCEEECCCCCCHHHHHHHH
LGWTSEQITERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLF
HCCCHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
FKEKRYDLARVGRYKVNKKLGLHAGELITSSTLTEEDVVATIEYLVRLHEGQSTMTVPGG
HHHHHHHHHHHCHHEECCHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEECCCC
VEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTTQDVEAITPQTLINI
EECCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHY
HHHHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCHHHCCCEEEECCCCCC
GRMCPIETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIEYLTADEEDRHV
CCCCCCCCCCCCCEEEEECEEEEEEECCCCCCCCCHHHHHHHHHHCCHHEEECCCCCCEE
VAQANSPIDEAGRFLEPRVLVRRKAGEVEYVASSEVDYMDVSPRQMVSVATAMIPFLEHD
EEECCCCHHHHHHHCCCHHHHHHCCCCEEEEECCCCCEECCCHHHHHHHHHHHHHHHCCC
DANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGHVVVAEKSGVIEEVSADYITV
CCCCEEECCCCHHHCCCHHHCCCCEEECCCCEEEEECCCEEEEEECCCCHHHCCCCEEEE
MADDGTRRTYRMRKFARSNHGTCANQSPIVDAGDRVEAGQVIADGPCTENGEMALGKNLL
EECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEECCCEE
VAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEV
EEEECCCCCCCCCEEEECCHHHHHHHHHEEEEECCCCCCHHHCCCHHHHHHHCCCCCHHH
LADLDERGIVRIGAEVRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVP
HHCCCCCCEEEECCEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECC
HGESGKVIGIRVFSHEDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVIGKILP
CCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEECC
AEDMPFLPDGTPVDIILNTHGVPRRMNVGQILETHLGWVAKSGWKIDVAGGIPDWAVNLP
CCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHCCCH
EELLHAAPNQIVSTPVFDGAKEEELQGLLSSTLPNRDGDVMVGGDGKAVLFDGRSGEPFP
HHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCCCC
YPVTVGYMYIMKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYG
CCHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHHH
AAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVLSS
HHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEC
DGAAIELREGEDEDLERAAANLGINLSRNESASIEDLA
CCCEEEECCCCCHHHHHHHHHCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]