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The map label for this gene is rrmA [C]

Identifier: 221230394

GI number: 221230394

Start: 2066035

End: 2066877

Strand: Direct

Name: rrmA [C]

Synonym: MLBr_01713

Alternate gene names: 221230394

Gene position: 2066035-2066877 (Clockwise)

Preceding gene: 221230387

Following gene: 221230395

Centisome position: 63.22

GC content: 60.14

Gene sequence:

>843_bases
ATGAGCGCATTCGTCCCCGACGTTCCCAACCGCATACCCGACGACCCCTCGTCAATCGACTCCACCGCATTCCACGGCAT
GCTGACGCTGACAGGTGAACGCACCATCCCCGATCTGGATATCGAAAACTACTGGTTCCGCCGCCATCAGGTGGTTTACC
AGTGGCTGGCGCAGCGCTGCACCGGCTGTGAGGTTCTCGAGGCCGGCTGCGGCGAGGGCTACGGAGCCGATCTGATCGTC
GACGTTGCCTACCGGGTCATTGCGGTGGACTACGACGAGGCCACAGTGGCCCATGTCCGTAGCCGTTACCCGAGAGTCCA
GGTTATGCAAGCAAACCTGATTGAGTTGCCGCTGGCCGACGCTTCGGTGGACGTCGTGGTGAACTTCCAAGTAATCGAAC
ATCTGTGGAATCAGGCCCAGTTCGTCAGCGAGTGCGCCCGAGTGCTGCGTCCCTCGGGGTTACTGATGGTGTCCACCCCA
AACCGAATCACCTTTTCACCGGGGCGTGACACATCGATCAACCCGTTTCACACCCGTGAGCTGAACGCCGACGAGTTGAC
CCAATTGCTTATCACCGCAGATTTTTCCGAGGTAGCCATGTACGGATTGTTTCATGGACCGCGCCTGAAGGAAATGGATG
CCCGCCACGGCGGCTCCATCATCGACGCGCAAATCGCACGTGCGGTGAGCAACGCACCATGGCCGCCCGAACTGGTGGCA
GACGTCGCCGCGGTTACCGCTGCCGACTTTGACATCATCGAGGCATCAGCGGGCCCAGAGGCCAGCGATGGTAGGGACGT
CGATGAAAGTCTGGATCTAATCGCGATCGCAGTGCGCCGATGA

Upstream 100 bases:

>100_bases
GGGTCGCATCTGCGCAATTGCCTGCTGTTCCTCACCGCCGTTAGCACAGAAGGCTCTAGCGGTTCGCGAATCTGGCGGTT
CGGGTTAGCCTGCCTTAACA

Downstream 100 bases:

>100_bases
ACACATCCGCAAACCCAGTGCCCGGTCTGTTCACCCTGGTGCTACACACCCACTTGCCGTGGCTAGCCCACCACGGCCGC
TGGCCGGTCGGTGAGGAATG

Product: hypothetical protein

Products: S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

Alternate protein names: Methyltransferase; Glycosyl Transferase Family Protein; Glycosyltransferase; Glycosyl Transferase; Ubiquinone/Menaquinone Biosynthesis Methylase-Like Protein; Methyltransferase Family Protein; Methyltransferase Domain Protein; Methyltransferase And Glycosyltransferase; Methyltransferase Domain Family; 3-Demethylubiquinone-9 3-O-Methyltransferase; Sam Dependent Methyltransferase

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MSAFVPDVPNRIPDDPSSIDSTAFHGMLTLTGERTIPDLDIENYWFRRHQVVYQWLAQRCTGCEVLEAGCGEGYGADLIV
DVAYRVIAVDYDEATVAHVRSRYPRVQVMQANLIELPLADASVDVVVNFQVIEHLWNQAQFVSECARVLRPSGLLMVSTP
NRITFSPGRDTSINPFHTRELNADELTQLLITADFSEVAMYGLFHGPRLKEMDARHGGSIIDAQIARAVSNAPWPPELVA
DVAAVTAADFDIIEASAGPEASDGRDVDESLDLIAIAVRR

Sequences:

>Translated_280_residues
MSAFVPDVPNRIPDDPSSIDSTAFHGMLTLTGERTIPDLDIENYWFRRHQVVYQWLAQRCTGCEVLEAGCGEGYGADLIV
DVAYRVIAVDYDEATVAHVRSRYPRVQVMQANLIELPLADASVDVVVNFQVIEHLWNQAQFVSECARVLRPSGLLMVSTP
NRITFSPGRDTSINPFHTRELNADELTQLLITADFSEVAMYGLFHGPRLKEMDARHGGSIIDAQIARAVSNAPWPPELVA
DVAAVTAADFDIIEASAGPEASDGRDVDESLDLIAIAVRR
>Mature_279_residues
SAFVPDVPNRIPDDPSSIDSTAFHGMLTLTGERTIPDLDIENYWFRRHQVVYQWLAQRCTGCEVLEAGCGEGYGADLIVD
VAYRVIAVDYDEATVAHVRSRYPRVQVMQANLIELPLADASVDVVVNFQVIEHLWNQAQFVSECARVLRPSGLLMVSTPN
RITFSPGRDTSINPFHTRELNADELTQLLITADFSEVAMYGLFHGPRLKEMDARHGGSIIDAQIARAVSNAPWPPELVAD
VAAVTAADFDIIEASAGPEASDGRDVDESLDLIAIAVRR

Specific function: Specifically Methylates The Guanosine In Position 745 Of 23s rRNA. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.51 [C]

Molecular weight: Translated: 30835; Mature: 30704

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFVPDVPNRIPDDPSSIDSTAFHGMLTLTGERTIPDLDIENYWFRRHQVVYQWLAQRC
CCCCCCCCCCCCCCCCCCCCHHHHCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHC
TGCEVLEAGCGEGYGADLIVDVAYRVIAVDYDEATVAHVRSRYPRVQVMQANLIELPLAD
CCCHHHHCCCCCCCCCHHHHEEHEEEEEECCCHHHHHHHHHHCCCEEEEECCCEECCCCC
ASVDVVVNFQVIEHLWNQAQFVSECARVLRPSGLLMVSTPNRITFSPGRDTSINPFHTRE
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCCCCCC
LNADELTQLLITADFSEVAMYGLFHGPRLKEMDARHGGSIIDAQIARAVSNAPWPPELVA
CCHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHH
DVAAVTAADFDIIEASAGPEASDGRDVDESLDLIAIAVRR
HHHHHHHCCCCEEECCCCCCCCCCCCHHHHHCEEEEEECC
>Mature Secondary Structure 
SAFVPDVPNRIPDDPSSIDSTAFHGMLTLTGERTIPDLDIENYWFRRHQVVYQWLAQRC
CCCCCCCCCCCCCCCCCCCHHHHCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHC
TGCEVLEAGCGEGYGADLIVDVAYRVIAVDYDEATVAHVRSRYPRVQVMQANLIELPLAD
CCCHHHHCCCCCCCCCHHHHEEHEEEEEECCCHHHHHHHHHHCCCEEEEECCCEECCCCC
ASVDVVVNFQVIEHLWNQAQFVSECARVLRPSGLLMVSTPNRITFSPGRDTSINPFHTRE
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCCCCCC
LNADELTQLLITADFSEVAMYGLFHGPRLKEMDARHGGSIIDAQIARAVSNAPWPPELVA
CCHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHH
DVAAVTAADFDIIEASAGPEASDGRDVDESLDLIAIAVRR
HHHHHHHCCCCEEECCCCCCCCCCCCHHHHHCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Unidentified protein factor B [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; rRNA [C]

Specific reaction: S-Adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

General reaction: Methyl group transfer [C]

Inhibitor: Mg2+; Unidentified protein factor A1 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA