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The map label for this gene is aceE [H]

Identifier: 221230346

GI number: 221230346

Start: 1989091

End: 1991901

Strand: Direct

Name: aceE [H]

Synonym: MLBr_01651

Alternate gene names: 221230346

Gene position: 1989091-1991901 (Clockwise)

Preceding gene: 221230344

Following gene: 221230347

Centisome position: 60.86

GC content: 60.19

Gene sequence:

>2811_bases
TTGACAATCGAGTTCGCGCGCCCGGATCTGGCCAAAAACCCTAGCAGCACAAACGAATCCAACAGCGTTCGGGTGATCCG
CGAAGGTGTGGCGTCGTATTTGCCCGATATCGACCCCGAGGAGACAGCGGAGTGGCTGGAGTCCTTCGACGAATTGCTGA
AGCACTCAGGGCCGTCGCGGGCACGATATCTGATACTACGGCTACTGGAGCGGGCCGGCGAGCAGCGGGTGACGATCCCG
GCGTTGACATGGACCGACTACGTCAACACCATCCCGACCGAGCTCGAGCCGTGGTTCCCCGGAGACGAGGACATCGAACG
TCGCTACCGCACCTGGATCAGATGGAACGCGGCAATTATGGTGCACCGCGCGCAACGACCGGGTGTGGGCGTCGGTGGTC
ATATCTCTACCTATGCTTCGTCCGCTGCGCTCTACGAGGTAGGGTTCAACCACTTTTTCCGAGGAAAGTCGCATCCCAGC
GGCGGAGATCAGGTATTCATCCAGGGCCACGCGTCCCCCGGAATTTACGCCCGTGCCTTCCTGGAAGGCCGATTGTCCGC
AGACCAGCTTGATGGTTTCCGCCAGGAGCACAGTCATCCGGGAGGCGGGTTGCCGTCCTACCCACACCCACGACTGATGC
CCGACTTCTGGGAATTCCCCACCGTGTCGATGGGTCTGGGCCCGCTCAATGCCATTTACCAGGCACGGTTCAACCGCTAT
CTTCATGACCGGGGTATCAAGGATACCTCCGACCAACACGTGTGGTGTTTTTTAGGCGACGGTGAAATGGACGAGCCCGA
AAGCCGCGGGCTCGCACATGTCGCGTCCCTCGAAGACCTGGACAATCTGATCTTCGTCATCAACTGCAATCTGCAGCGCC
TCGACGGTCCAGTACGTGGTAACGGCAAGATCATCCAGGAGCTGGAGTCATTCTTCCGCGGAGCCGGTTGGAACGTCATC
AAGGTAGTGTGGGGCCGTGAATGGGACGCGCTGCTACATGCCGACCGGGACGGCGCCCTGGTCGATCTGATGAACGCCAC
CCCTGACGGTGATTACCAAACGTACAAAGCCAACGATGGCCGCTTTGTCCGCGACCATTTCTTCGGGCGCGACCCTCGTA
CCAAGGCTCTGGTGGAACATATGAGCGACCAAGAGATCTGGAACCTCAAGCGCGGCGGTCACGACTACCGTAAAGTTTAC
GCCTCCTATCGCGCCGCCGTCGACCACAAGGGACAGCCAACAGTGATCTTGGCCAAGACCATCAAGGGTTACGCGCTGGG
CAAACATTTCGAGAGCCGCAATGCCACTCACCAGATGAAAAAGCTTACGCTGGAAGATCTTAAGGAGTTTCGTGATACCC
AGCGGATTCCGATTTCAGACACCGAATTAGAGGAAAATCCTTACCTACCACCGTATTACCATCCCGGACCCGACTCACCG
GAAATCCGTTATCTGCTCGACCGACGCCGCGCCCTCGGGGGTTTTCTGCCCGAGCGCCGGACAAAGTCCGGCGCGCTAAC
GCTTCCCGGCCGCGACACCTACGCCGCGTTGAAGACCGGATCGGGTCAGCAGGAAGTCGCCACCACCATGGCGATCGTGC
GCACATTCAAAGAAGTGTTGCGACACAAGGAAGTCGGCCCACGGATCGTCCCGATCATTCCCGACGAAGCGCGCACGTTC
GGCATGGACTCGTGGTTTCCGTCGTTGAAGATCTATAACCACAACGGCCAGCTTTACACCGCCGTCGACGCACAACTGAT
GCTGGCGTACAAGGAGAGCGAAGTCGGGCAGATCCTGCACGAAGGCATTGACGAGGCCGGGTCGGTGGGCTCATTCATCG
CGGCAGGCACATCGTATTCGACGCACAACGAGCCAATGATTCCAATCTACATCTTCTATTCGATGTTCGGGTTCCAACGC
ACCGGCGACGGCCTGTGGGCCGCGGCCGACCAAATGGCGCGGGGCTTCCTACTCGGGGCCACCGCGGGACGTACCACGCT
GACCGGCGAGGGGCTGCAACACGCCGACGGCCACTCGTTGCTGTTAGCGGCCACCAATCCGGCAGTCGTCACGTACGATC
CGGCGTTCGCCTACGAAATCGCCTATATCGTCGAAAGCGGGCTGACCCGGATGTTTGGGGAGGACCCGGAAAACGTGTTC
TTTTACATCACCGTCTACAACGAACCATACCCACAGCCACCCGAGCCGGAGAACTTCGATCCCGACGGAGTACTGCGCGG
CATGTACCGCTACTACACGGCTAAGGAACAACGTTCCAACAAGGCGCACATCTTGGCCTCCGGGGTGTCAATGCCTGCGG
CACTGACGGCAGCCGAGATGCTGTCCACCCAGTGGGATGTCGCTGCCGACGTATGGTCGGTGACCAGTTGGGGCGAACTG
AACCGCGACGGGATGTCCATCGAAACGGCCCGGCTGCGTTACCCCGACCAACCGACGAGCGTCCCCTACGTGACCCAGGT
CTTATCCGAAGCCCGCTCGGATAACGCCGGACCGGTAATCGCCGTATCGGACTGGATGCGCGCGGTGCCCGAACAGATCC
GACCATGGGTTCCTGGCACCTACGTCACGCTGGGCACTGACGGGTTCGGTTTTTCCGACACCCGTACAGCCACTCGACGC
TATTTCAACACCGATGCCGAATCGCAGGTGGTCGCGGTATTGGAGGCGCTGGCACGTGACGGTGAGATCGACCCGTCGGT
GCCGGTCGCGGCCACACGTCAATACCAGATCGACGACGTGCAGGCCGCCCCAGAGCAGACTTCTGATCCGGGACCGGGAG
TTCAGAACTGA

Upstream 100 bases:

>100_bases
ACGGCCCGAAATACCGGTGCGGCACGATAGGGGGCGATGGTCCAGATAGCCCCAAAGGCATCATCCCAAATAATGCCCCG
CCAACTACAGGAGTAGTGCG

Downstream 100 bases:

>100_bases
CATAATCCGGTCCCCGGTAAGACACCAGTAAGAGCCGAGCATTGTTTTGGGGAAAACTTCCAGAAATCTGGCGTAGCTTT
TAGGAGTGAATCACAATCAT

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 936; Mature: 935

Protein sequence:

>936_residues
MTIEFARPDLAKNPSSTNESNSVRVIREGVASYLPDIDPEETAEWLESFDELLKHSGPSRARYLILRLLERAGEQRVTIP
ALTWTDYVNTIPTELEPWFPGDEDIERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPS
GGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNRY
LHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVASLEDLDNLIFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVI
KVVWGREWDALLHADRDGALVDLMNATPDGDYQTYKANDGRFVRDHFFGRDPRTKALVEHMSDQEIWNLKRGGHDYRKVY
ASYRAAVDHKGQPTVILAKTIKGYALGKHFESRNATHQMKKLTLEDLKEFRDTQRIPISDTELEENPYLPPYYHPGPDSP
EIRYLLDRRRALGGFLPERRTKSGALTLPGRDTYAALKTGSGQQEVATTMAIVRTFKEVLRHKEVGPRIVPIIPDEARTF
GMDSWFPSLKIYNHNGQLYTAVDAQLMLAYKESEVGQILHEGIDEAGSVGSFIAAGTSYSTHNEPMIPIYIFYSMFGFQR
TGDGLWAAADQMARGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVTYDPAFAYEIAYIVESGLTRMFGEDPENVF
FYITVYNEPYPQPPEPENFDPDGVLRGMYRYYTAKEQRSNKAHILASGVSMPAALTAAEMLSTQWDVAADVWSVTSWGEL
NRDGMSIETARLRYPDQPTSVPYVTQVLSEARSDNAGPVIAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSDTRTATRR
YFNTDAESQVVAVLEALARDGEIDPSVPVAATRQYQIDDVQAAPEQTSDPGPGVQN

Sequences:

>Translated_936_residues
MTIEFARPDLAKNPSSTNESNSVRVIREGVASYLPDIDPEETAEWLESFDELLKHSGPSRARYLILRLLERAGEQRVTIP
ALTWTDYVNTIPTELEPWFPGDEDIERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPS
GGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNRY
LHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVASLEDLDNLIFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVI
KVVWGREWDALLHADRDGALVDLMNATPDGDYQTYKANDGRFVRDHFFGRDPRTKALVEHMSDQEIWNLKRGGHDYRKVY
ASYRAAVDHKGQPTVILAKTIKGYALGKHFESRNATHQMKKLTLEDLKEFRDTQRIPISDTELEENPYLPPYYHPGPDSP
EIRYLLDRRRALGGFLPERRTKSGALTLPGRDTYAALKTGSGQQEVATTMAIVRTFKEVLRHKEVGPRIVPIIPDEARTF
GMDSWFPSLKIYNHNGQLYTAVDAQLMLAYKESEVGQILHEGIDEAGSVGSFIAAGTSYSTHNEPMIPIYIFYSMFGFQR
TGDGLWAAADQMARGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVTYDPAFAYEIAYIVESGLTRMFGEDPENVF
FYITVYNEPYPQPPEPENFDPDGVLRGMYRYYTAKEQRSNKAHILASGVSMPAALTAAEMLSTQWDVAADVWSVTSWGEL
NRDGMSIETARLRYPDQPTSVPYVTQVLSEARSDNAGPVIAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSDTRTATRR
YFNTDAESQVVAVLEALARDGEIDPSVPVAATRQYQIDDVQAAPEQTSDPGPGVQN
>Mature_935_residues
TIEFARPDLAKNPSSTNESNSVRVIREGVASYLPDIDPEETAEWLESFDELLKHSGPSRARYLILRLLERAGEQRVTIPA
LTWTDYVNTIPTELEPWFPGDEDIERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPSG
GDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNRYL
HDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVASLEDLDNLIFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIK
VVWGREWDALLHADRDGALVDLMNATPDGDYQTYKANDGRFVRDHFFGRDPRTKALVEHMSDQEIWNLKRGGHDYRKVYA
SYRAAVDHKGQPTVILAKTIKGYALGKHFESRNATHQMKKLTLEDLKEFRDTQRIPISDTELEENPYLPPYYHPGPDSPE
IRYLLDRRRALGGFLPERRTKSGALTLPGRDTYAALKTGSGQQEVATTMAIVRTFKEVLRHKEVGPRIVPIIPDEARTFG
MDSWFPSLKIYNHNGQLYTAVDAQLMLAYKESEVGQILHEGIDEAGSVGSFIAAGTSYSTHNEPMIPIYIFYSMFGFQRT
GDGLWAAADQMARGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVTYDPAFAYEIAYIVESGLTRMFGEDPENVFF
YITVYNEPYPQPPEPENFDPDGVLRGMYRYYTAKEQRSNKAHILASGVSMPAALTAAEMLSTQWDVAADVWSVTSWGELN
RDGMSIETARLRYPDQPTSVPYVTQVLSEARSDNAGPVIAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSDTRTATRRY
FNTDAESQVVAVLEALARDGEIDPSVPVAATRQYQIDDVQAAPEQTSDPGPGVQN

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI133778974, Length=220, Percent_Identity=29.5454545454545, Blast_Score=70, Evalue=8e-12,
Organism=Escherichia coli, GI1786304, Length=892, Percent_Identity=51.2331838565022, Blast_Score=911, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 104703; Mature: 104572

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIEFARPDLAKNPSSTNESNSVRVIREGVASYLPDIDPEETAEWLESFDELLKHSGPSR
CEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHH
ARYLILRLLERAGEQRVTIPALTWTDYVNTIPTELEPWFPGDEDIERRYRTWIRWNAAIM
HHHHHHHHHHHCCCCEEEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHEECEEEE
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPSGGDQVFIQGHASPGIYARAF
EEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHH
LEGRLSADQLDGFRQEHSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNRY
HHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHH
LHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVASLEDLDNLIFVINCNLQRLDGPVRG
HHHCCCCCCCCCEEEEEECCCCCCCCHHCCHHHHHHHHCCCCEEEEEECCHHHCCCCCCC
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVDLMNATPDGDYQTYKANDG
CCHHHHHHHHHHCCCCCEEEEEEECCCHHHHEECCCCCCEEEEECCCCCCCCEEEECCCC
RFVRDHFFGRDPRTKALVEHMSDQEIWNLKRGGHDYRKVYASYRAAVDHKGQPTVILAKT
CCHHHHHCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEC
IKGYALGKHFESRNATHQMKKLTLEDLKEFRDTQRIPISDTELEENPYLPPYYHPGPDSP
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EIRYLLDRRRALGGFLPERRTKSGALTLPGRDTYAALKTGSGQQEVATTMAIVRTFKEVL
HHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
RHKEVGPRIVPIIPDEARTFGMDSWFPSLKIYNHNGQLYTAVDAQLMLAYKESEVGQILH
HHHCCCCEEEEECCCCHHHCCCCCCCCCEEEEECCCCEEEEECEEEEEEECHHHHHHHHH
EGIDEAGSVGSFIAAGTSYSTHNEPMIPIYIFYSMFGFQRTGDGLWAAADQMARGFLLGA
HHHHHCCCCCHHHCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCHHHHHHHHHCCEEEEC
TAGRTTLTGEGLQHADGHSLLLAATNPAVVTYDPAFAYEIAYIVESGLTRMFGEDPENVF
CCCCCEECCCCCCCCCCCEEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEE
FYITVYNEPYPQPPEPENFDPDGVLRGMYRYYTAKEQRSNKAHILASGVSMPAALTAAEM
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
LSTQWDVAADVWSVTSWGELNRDGMSIETARLRYPDQPTSVPYVTQVLSEARSDNAGPVI
HHCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEE
AVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSDTRTATRRYFNTDAESQVVAVLEALARD
EHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCC
GEIDPSVPVAATRQYQIDDVQAAPEQTSDPGPGVQN
CCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TIEFARPDLAKNPSSTNESNSVRVIREGVASYLPDIDPEETAEWLESFDELLKHSGPSR
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHH
ARYLILRLLERAGEQRVTIPALTWTDYVNTIPTELEPWFPGDEDIERRYRTWIRWNAAIM
HHHHHHHHHHHCCCCEEEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHEECEEEE
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPSGGDQVFIQGHASPGIYARAF
EEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHH
LEGRLSADQLDGFRQEHSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNRY
HHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHH
LHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVASLEDLDNLIFVINCNLQRLDGPVRG
HHHCCCCCCCCCEEEEEECCCCCCCCHHCCHHHHHHHHCCCCEEEEEECCHHHCCCCCCC
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVDLMNATPDGDYQTYKANDG
CCHHHHHHHHHHCCCCCEEEEEEECCCHHHHEECCCCCCEEEEECCCCCCCCEEEECCCC
RFVRDHFFGRDPRTKALVEHMSDQEIWNLKRGGHDYRKVYASYRAAVDHKGQPTVILAKT
CCHHHHHCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEC
IKGYALGKHFESRNATHQMKKLTLEDLKEFRDTQRIPISDTELEENPYLPPYYHPGPDSP
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EIRYLLDRRRALGGFLPERRTKSGALTLPGRDTYAALKTGSGQQEVATTMAIVRTFKEVL
HHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
RHKEVGPRIVPIIPDEARTFGMDSWFPSLKIYNHNGQLYTAVDAQLMLAYKESEVGQILH
HHHCCCCEEEEECCCCHHHCCCCCCCCCEEEEECCCCEEEEECEEEEEEECHHHHHHHHH
EGIDEAGSVGSFIAAGTSYSTHNEPMIPIYIFYSMFGFQRTGDGLWAAADQMARGFLLGA
HHHHHCCCCCHHHCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCHHHHHHHHHCCEEEEC
TAGRTTLTGEGLQHADGHSLLLAATNPAVVTYDPAFAYEIAYIVESGLTRMFGEDPENVF
CCCCCEECCCCCCCCCCCEEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEE
FYITVYNEPYPQPPEPENFDPDGVLRGMYRYYTAKEQRSNKAHILASGVSMPAALTAAEM
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
LSTQWDVAADVWSVTSWGELNRDGMSIETARLRYPDQPTSVPYVTQVLSEARSDNAGPVI
HHCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEE
AVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSDTRTATRRYFNTDAESQVVAVLEALARD
EHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCC
GEIDPSVPVAATRQYQIDDVQAAPEQTSDPGPGVQN
CCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]