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The map label for this gene is cdsA

Identifier: 221230310

GI number: 221230310

Start: 1913823

End: 1914761

Strand: Reverse

Name: cdsA

Synonym: MLBr_01589

Alternate gene names: 221230310

Gene position: 1914761-1913823 (Counterclockwise)

Preceding gene: 221230311

Following gene: 221230308

Centisome position: 58.59

GC content: 59.42

Gene sequence:

>939_bases
GTGGCTTCCACCGATCCCGGCACAGGCACCCCGCTTGACGAGTCGGTGCCTGGGATCAAGAGGGCTATGCGGCAATCGAC
TAAGAATACCCCCCGGGCGGGACGTAATCTGCCCGCCGCGATCGCGGTGGGCTTAAGTATTGGTGGTGTTCTCGTCGCAA
CGCTGGTGTTTGCTCCGCGAATCTGGGTTGTCTTGTGCGCTGGCGCCATTTTCGTTGCTAGCCATGAGGTGGTGCGGCGG
CTACGGGAAGCTGGATATGTGATTCCGGCTATCCCGCTGCTCATCGGTGGGCAGTTCACCGTCTGGTTAACTTGGCCGTA
TCGCACCGTTGGTGCATTGGCTGGCTTCGGTGCGACGGTGGTGGTCTGCATGATTTGGCGGCTTGTCATGCACGACAACA
GCAAGCAGCACGAATCTCGGGAAGCTTTGGCAGGTCCGCCGGTGTCAAATTACCTGCGGGACGCGTCGGCCACCGTTTTT
TTGGCCGCGTGGGTCCCGTTGTTTGCCTCGTTCGCAGCATTGCTGGTTTATCCGAAGGATGGTGCGGGCCGGGTATTCTG
CCTGATGATTGCGGTGGTAGCTTCCGATGTGGGTGGTTACACAGTAGGGGTACTTTTCGGCAAACATCCACTGGTTCCAA
GGATTAGCCCGAATAAGTCCTGGGAGGGATTCGCCGGTTCGCTGGTCTGCGGGACCACCGCAACCATCCTGACTGCTACC
TTCCTGGCTGGCAAAACACCGTGGGTTGGGGCTTTGCTCAGTTTTGTACTGGTGCTCACCTGCACGCTGGGGGATTTGGT
GGAGTCCCAAGTTAAGCGCGACCTCGGCATCAAAGATATGGGCCGGCTGCTACCCGGCCACGGTGGCCTGATGGACCGGC
TTGATGGTGTGCTGCCGTCGGCGGTTGTAGCTTGGACCATGCTTACGTTGCTGCCCTGA

Upstream 100 bases:

>100_bases
ACCCACCAGTACGTTATCCAGATTGACGAACTGGTCAAGCACAAAGAAGGTGAGCTGCTGGAGGTCTAGCGGCCGTTCAG
CAGCTAATTCATTCAGGTCC

Downstream 100 bases:

>100_bases
CAAGGCTGGTACCGGACAGATTATGGCCCAAGAGTTGGTGTTCTCTGAGCCGTGTCCAGGCCGACTGCCGTGGCACTTGG
CCGACCTCGACGCGGTCGGT

Product: putative phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MASTDPGTGTPLDESVPGIKRAMRQSTKNTPRAGRNLPAAIAVGLSIGGVLVATLVFAPRIWVVLCAGAIFVASHEVVRR
LREAGYVIPAIPLLIGGQFTVWLTWPYRTVGALAGFGATVVVCMIWRLVMHDNSKQHESREALAGPPVSNYLRDASATVF
LAAWVPLFASFAALLVYPKDGAGRVFCLMIAVVASDVGGYTVGVLFGKHPLVPRISPNKSWEGFAGSLVCGTTATILTAT
FLAGKTPWVGALLSFVLVLTCTLGDLVESQVKRDLGIKDMGRLLPGHGGLMDRLDGVLPSAVVAWTMLTLLP

Sequences:

>Translated_312_residues
MASTDPGTGTPLDESVPGIKRAMRQSTKNTPRAGRNLPAAIAVGLSIGGVLVATLVFAPRIWVVLCAGAIFVASHEVVRR
LREAGYVIPAIPLLIGGQFTVWLTWPYRTVGALAGFGATVVVCMIWRLVMHDNSKQHESREALAGPPVSNYLRDASATVF
LAAWVPLFASFAALLVYPKDGAGRVFCLMIAVVASDVGGYTVGVLFGKHPLVPRISPNKSWEGFAGSLVCGTTATILTAT
FLAGKTPWVGALLSFVLVLTCTLGDLVESQVKRDLGIKDMGRLLPGHGGLMDRLDGVLPSAVVAWTMLTLLP
>Mature_311_residues
ASTDPGTGTPLDESVPGIKRAMRQSTKNTPRAGRNLPAAIAVGLSIGGVLVATLVFAPRIWVVLCAGAIFVASHEVVRRL
REAGYVIPAIPLLIGGQFTVWLTWPYRTVGALAGFGATVVVCMIWRLVMHDNSKQHESREALAGPPVSNYLRDASATVFL
AAWVPLFASFAALLVYPKDGAGRVFCLMIAVVASDVGGYTVGVLFGKHPLVPRISPNKSWEGFAGSLVCGTTATILTATF
LAGKTPWVGALLSFVLVLTCTLGDLVESQVKRDLGIKDMGRLLPGHGGLMDRLDGVLPSAVVAWTMLTLLP

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family

Homologues:

Organism=Escherichia coli, GI87081696, Length=160, Percent_Identity=40.625, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787677, Length=167, Percent_Identity=34.7305389221557, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDSA_MYCLE (Q9CBU1)

Other databases:

- EMBL:   AL583922
- PIR:   G87107
- RefSeq:   NP_302096.1
- EnsemblBacteria:   EBMYCT00000028010
- GeneID:   909784
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML1589
- NMPDR:   fig|272631.1.peg.968
- Leproma:   ML1589
- GeneTree:   EBGT00050000017496
- HOGENOM:   HBG732679
- OMA:   KDMGTLL
- ProtClustDB:   CLSK792142
- BioCyc:   MLEP272631:ML1589-MONOMER
- BRENDA:   2.7.7.41
- InterPro:   IPR000374

Pfam domain/function: PF01148 CTP_transf_1

EC number: =2.7.7.41

Molecular weight: Translated: 32972; Mature: 32841

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2a48f7c8)-; HASH(0x2a2d9660)-; HASH(0x2a3bf07c)-; HASH(0x29ea9fe8)-; HASH(0x298ea854)-; HASH(0x2a36d1ac)-; HASH(0x2a26c4e4)-; HASH(0x2a3c3fb4)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTDPGTGTPLDESVPGIKRAMRQSTKNTPRAGRNLPAAIAVGLSIGGVLVATLVFAPR
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IWVVLCAGAIFVASHEVVRRLREAGYVIPAIPLLIGGQFTVWLTWPYRTVGALAGFGATV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHH
VVCMIWRLVMHDNSKQHESREALAGPPVSNYLRDASATVFLAAWVPLFASFAALLVYPKD
HHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
GAGRVFCLMIAVVASDVGGYTVGVLFGKHPLVPRISPNKSWEGFAGSLVCGTTATILTAT
CCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FLAGKTPWVGALLSFVLVLTCTLGDLVESQVKRDLGIKDMGRLLPGHGGLMDRLDGVLPS
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHH
AVVAWTMLTLLP
HHHHHHHHHHCH
>Mature Secondary Structure 
ASTDPGTGTPLDESVPGIKRAMRQSTKNTPRAGRNLPAAIAVGLSIGGVLVATLVFAPR
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IWVVLCAGAIFVASHEVVRRLREAGYVIPAIPLLIGGQFTVWLTWPYRTVGALAGFGATV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHH
VVCMIWRLVMHDNSKQHESREALAGPPVSNYLRDASATVFLAAWVPLFASFAALLVYPKD
HHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
GAGRVFCLMIAVVASDVGGYTVGVLFGKHPLVPRISPNKSWEGFAGSLVCGTTATILTAT
CCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FLAGKTPWVGALLSFVLVLTCTLGDLVESQVKRDLGIKDMGRLLPGHGGLMDRLDGVLPS
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHH
AVVAWTMLTLLP
HHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11234002