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The map label for this gene is 221230175

Identifier: 221230175

GI number: 221230175

Start: 1598315

End: 1599121

Strand: Reverse

Name: 221230175

Synonym: MLBr_01340

Alternate gene names: NA

Gene position: 1599121-1598315 (Counterclockwise)

Preceding gene: 221230176

Following gene: 221230174

Centisome position: 48.93

GC content: 62.95

Gene sequence:

>807_bases
ATGTCCGACTTTGAAACCGGTCCAGCAGCCAGCACCACCGCTGGCCGAGCCGCCCAGACGCCGCTGTTAATGCTCACCTC
TGGGCGCTATCTCGACGACGACGAACTCTCCCAGCTCTACGGCTACCCGTCCGAACGCGCCGGCGTCTGGATACGGGCAA
ACTTCATCACCAGTATAGACGGCGGTGCCACCGCCGACGGCAGGACCGGCGCCATGGCAGGGCCAGGCGACCGATTTGTG
TTCAACATGCTGCGCGAACTCGCTGATGTGATCGTCGTCGGCGCGGGCACCGTACGGATCGAGAACTATTCCGGCGCGCA
CCTGCCGGTAACCAAGCGCCAGCAGCGGCAGGCCCGCGGCCAAAGTGAAGTCCCCCAATTAGCGATTGTCACAAATTCGG
GTCGGCTGGATCGGGATATGGCGGTGTTTACCCGGACCGAGATAGCACCACTGGTGCTCACCTGTACGGAGACCGCCAAG
AAGCTGCGCACGCGGTTAGCTGATCTTGCCTACGTGGTCAGCTGCTCTGGCGACGATCCCAGCAAGGTCGACGAGACTGT
CGTATTGGCGACCCTACAGACTCGCGGTCTGCGCCGGGTCCTTACCGAAGGCGGGCCGATGCTGCTCGGCTCGTTTATCC
AGCACGGCATGCTCGACGAGCTGTGTCTGACCATCGCACCTTTGATAGTGGGCGGCCGGGCTCGACGTATCGCGACAGGC
CCGGAGCAGCTGCTCACCCGTATGCGCTGTGCCCACGTTCTCACTGACGATGCCGGCTACCTTTACACCCGCTACGTCAA
GGCCTGA

Upstream 100 bases:

>100_bases
CGATCCACCAGGTGCCCCACCCGGAACGACGCTTCGGGTGGGTTTGCAGAGATGGACCTGTACATTGAAGACACTGTAGC
AACGTGCTGCAATCAAACGG

Downstream 100 bases:

>100_bases
CCCGGCGGCGGGAATGGCTACTGTGGTCGGCATGCGTTGGCACACCAGATCCGCCACGATTTTGGTTGCTGTTACCGCAT
TGCTGGTAGGTTGTGTCCCG

Product: hypothetical protein

Products: 5-amino-6-(5-phosphoribosylamino)uracil; NADPH; H+

Alternate protein names: Bifunctional Deaminase-Reductase Domain-Containing Protein; 5-Amino-6-(5-Phosphoribosylamino)Uracil Reductase; Deaminase-Reductase Domain-Containing Protein; Diaminohydroxyphosphoribosylaminopyrimidine Reductase; Hydrolase; Pyrimidine Reductase Riboflavin Biosynthesis; Bifunctional Deaminase/Reductase; Bifunctional Riboflavin Biosynthesis Protein RibD; Pyrimidine Reductase-Like Protein; Bifunctional Riboflavin Biosynthesis Protein RibD; Pyrimidine Reductase Riboflavin Biosynthesis-Like Protein; Riboflavin/Cytosine Deaminase; Pyrimidine Reductase; Reductase; RibD Domain-Containing Protein; Riboflavin-Specific Deaminase/Reductase; Riboflavin-Specific Deaminase; 5-Amino-6-(5-Phosphoribosylamino)Uracil Reductase Ribd

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSDFETGPAASTTAGRAAQTPLLMLTSGRYLDDDELSQLYGYPSERAGVWIRANFITSIDGGATADGRTGAMAGPGDRFV
FNMLRELADVIVVGAGTVRIENYSGAHLPVTKRQQRQARGQSEVPQLAIVTNSGRLDRDMAVFTRTEIAPLVLTCTETAK
KLRTRLADLAYVVSCSGDDPSKVDETVVLATLQTRGLRRVLTEGGPMLLGSFIQHGMLDELCLTIAPLIVGGRARRIATG
PEQLLTRMRCAHVLTDDAGYLYTRYVKA

Sequences:

>Translated_268_residues
MSDFETGPAASTTAGRAAQTPLLMLTSGRYLDDDELSQLYGYPSERAGVWIRANFITSIDGGATADGRTGAMAGPGDRFV
FNMLRELADVIVVGAGTVRIENYSGAHLPVTKRQQRQARGQSEVPQLAIVTNSGRLDRDMAVFTRTEIAPLVLTCTETAK
KLRTRLADLAYVVSCSGDDPSKVDETVVLATLQTRGLRRVLTEGGPMLLGSFIQHGMLDELCLTIAPLIVGGRARRIATG
PEQLLTRMRCAHVLTDDAGYLYTRYVKA
>Mature_267_residues
SDFETGPAASTTAGRAAQTPLLMLTSGRYLDDDELSQLYGYPSERAGVWIRANFITSIDGGATADGRTGAMAGPGDRFVF
NMLRELADVIVVGAGTVRIENYSGAHLPVTKRQQRQARGQSEVPQLAIVTNSGRLDRDMAVFTRTEIAPLVLTCTETAKK
LRTRLADLAYVVSCSGDDPSKVDETVVLATLQTRGLRRVLTEGGPMLLGSFIQHGMLDELCLTIAPLIVGGRARRIATGP
EQLLTRMRCAHVLTDDAGYLYTRYVKA

Specific function: Unknown

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.193

Molecular weight: Translated: 28981; Mature: 28849

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFETGPAASTTAGRAAQTPLLMLTSGRYLDDDELSQLYGYPSERAGVWIRANFITSID
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCEEEEEEEEEECC
GGATADGRTGAMAGPGDRFVFNMLRELADVIVVGAGTVRIENYSGAHLPVTKRQQRQARG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCEEEEECCCCCCCCCCHHHHHHHCC
QSEVPQLAIVTNSGRLDRDMAVFTRTEIAPLVLTCTETAKKLRTRLADLAYVVSCSGDDP
CCCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHEEEEEECCCCC
SKVDETVVLATLQTRGLRRVLTEGGPMLLGSFIQHGMLDELCLTIAPLIVGGRARRIATG
CHHHHEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCC
PEQLLTRMRCAHVLTDDAGYLYTRYVKA
HHHHHHHHHHHHHHCCCCCEEEEEEECC
>Mature Secondary Structure 
SDFETGPAASTTAGRAAQTPLLMLTSGRYLDDDELSQLYGYPSERAGVWIRANFITSID
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCEEEEEEEEEECC
GGATADGRTGAMAGPGDRFVFNMLRELADVIVVGAGTVRIENYSGAHLPVTKRQQRQARG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCEEEEECCCCCCCCCCHHHHHHHCC
QSEVPQLAIVTNSGRLDRDMAVFTRTEIAPLVLTCTETAKKLRTRLADLAYVVSCSGDDP
CCCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHEEEEEECCCCC
SKVDETVVLATLQTRGLRRVLTEGGPMLLGSFIQHGMLDELCLTIAPLIVGGRARRIATG
CHHHHEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCC
PEQLLTRMRCAHVLTDDAGYLYTRYVKA
HHHHHHHHHHHHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-amino-6-(5-phosphoribitylamino)uracil; NADP+

Specific reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP+ = 5-amino-6-(5-phosphoribosylamino)uracil + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA