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The map label for this gene is corA [H]

Identifier: 221230012

GI number: 221230012

Start: 1253379

End: 1254488

Strand: Reverse

Name: corA [H]

Synonym: MLBr_01090

Alternate gene names: 221230012

Gene position: 1254488-1253379 (Counterclockwise)

Preceding gene: 221230015

Following gene: 221230007

Centisome position: 38.39

GC content: 58.38

Gene sequence:

>1110_bases
ATGTTCCCGGGGTTTGACCCGTTACCTGAAGCGCTGAGGCCGGTCACGAAGCCCCGACTGTACACGCCTCACGTACATCC
CATTTTCCCCCCGCTCACCGAGCCCTTGGTCGACTGCGGCGTCTATGTCGGAGGCCATCGGCTACCCGACAAATACACAA
CGTACACCGCCGCGCTGAGCAGGGTGCGCGAGATCGAACTGATGGGGAACGAGGGATTCGTCTGGATCGGGTTACACGAG
CCTGAAGCAAGCCACATGCATAACGTCGCCGACGTTTTCGGGCTACACCCCTTGGCAGTCGAGGACGCCGTGCACGCCCA
TCAGCGGCCCAAGTTGGAACGCTACGACGACACGTTGTTTCTGGTCCTCAAGACCGTCAATTATGTACCGCACGAATCGG
TGGTGCTGGCCCGCCAGATCGTCGAAACCGGCGAGGTGATGATCTTCGTCGGCAAGAATTTCGTGGTCACGGTCCGCCAC
GGCGAGCATGGTGAGCTGTCCGAGGTGCGTAAGCGAATGGATACCGACCCCGAGCATCTGCGGCTGGGCTCGTACGCTGT
GATGCATGCCATCTCGGACTACGTGGTAGACCGCTATTTAGCGGTGACCAATCTGATGGAAGGCGATATCGACGCCATCG
AGGAAGTGGCGTTTGCTCCCGGCCGCAAGCTCAACGTCGAGCCGATTTACCTACTCAAGCGCGAGGTCATCGAACTTCGC
CGCTGTGTTGCCCCGCTCTCCGCCGCACTCCAGCGAATGCAAACGGATAACAAAGACTTAATCTCCAAAGAATTGCGCCG
CTACCTGCGTGACGTAGCTGACCACCAGACCGAGGCCGCAGATCAAATAGCCAGCTATGACGACATGCTCAATTCACTAG
TACAGGCCGCATTGGCTCGTGTCGGGATGCAGCAGAACAACGATATGCGCAAGATGGCGGCCTGGGCCGGCATCGTGGCG
ATGCCCACTATGGTCGCCGCCATCTACGGTATGAACTTCCGTTTCATGCCCGAGCTGAACTGGACGTGGAGTTACCCGCT
GGTAATGGCCGGAATGACCATTGTCTGCCTGGTTCTTTACTGGCAATTCCGAAACAGGAACTGGCTGTAG

Upstream 100 bases:

>100_bases
TGGGACCCATTCCAACACTCAATCAGTCCTCCACTGTTCTGGCCAAAACGCGTACCATAAAACACCACCTAATAACACCT
GTGCCGCGATGGGGGTTGAG

Downstream 100 bases:

>100_bases
CCTGGCAACAATGCGTGCCGCAGCTGCCCGCCGTCAGTGAAATTGTGCAATACGGCGATTCGGATCCAGCACGTCGTCTG
CCATCCTGCCGCATAGCTTG

Product: putative membrane transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MFPGFDPLPEALRPVTKPRLYTPHVHPIFPPLTEPLVDCGVYVGGHRLPDKYTTYTAALSRVREIELMGNEGFVWIGLHE
PEASHMHNVADVFGLHPLAVEDAVHAHQRPKLERYDDTLFLVLKTVNYVPHESVVLARQIVETGEVMIFVGKNFVVTVRH
GEHGELSEVRKRMDTDPEHLRLGSYAVMHAISDYVVDRYLAVTNLMEGDIDAIEEVAFAPGRKLNVEPIYLLKREVIELR
RCVAPLSAALQRMQTDNKDLISKELRRYLRDVADHQTEAADQIASYDDMLNSLVQAALARVGMQQNNDMRKMAAWAGIVA
MPTMVAAIYGMNFRFMPELNWTWSYPLVMAGMTIVCLVLYWQFRNRNWL

Sequences:

>Translated_369_residues
MFPGFDPLPEALRPVTKPRLYTPHVHPIFPPLTEPLVDCGVYVGGHRLPDKYTTYTAALSRVREIELMGNEGFVWIGLHE
PEASHMHNVADVFGLHPLAVEDAVHAHQRPKLERYDDTLFLVLKTVNYVPHESVVLARQIVETGEVMIFVGKNFVVTVRH
GEHGELSEVRKRMDTDPEHLRLGSYAVMHAISDYVVDRYLAVTNLMEGDIDAIEEVAFAPGRKLNVEPIYLLKREVIELR
RCVAPLSAALQRMQTDNKDLISKELRRYLRDVADHQTEAADQIASYDDMLNSLVQAALARVGMQQNNDMRKMAAWAGIVA
MPTMVAAIYGMNFRFMPELNWTWSYPLVMAGMTIVCLVLYWQFRNRNWL
>Mature_369_residues
MFPGFDPLPEALRPVTKPRLYTPHVHPIFPPLTEPLVDCGVYVGGHRLPDKYTTYTAALSRVREIELMGNEGFVWIGLHE
PEASHMHNVADVFGLHPLAVEDAVHAHQRPKLERYDDTLFLVLKTVNYVPHESVVLARQIVETGEVMIFVGKNFVVTVRH
GEHGELSEVRKRMDTDPEHLRLGSYAVMHAISDYVVDRYLAVTNLMEGDIDAIEEVAFAPGRKLNVEPIYLLKREVIELR
RCVAPLSAALQRMQTDNKDLISKELRRYLRDVADHQTEAADQIASYDDMLNSLVQAALARVGMQQNNDMRKMAAWAGIVA
MPTMVAAIYGMNFRFMPELNWTWSYPLVMAGMTIVCLVLYWQFRNRNWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=80, Percent_Identity=38.75, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 42107; Mature: 42107

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPGFDPLPEALRPVTKPRLYTPHVHPIFPPLTEPLVDCGVYVGGHRLPDKYTTYTAALS
CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
RVREIELMGNEGFVWIGLHEPEASHMHNVADVFGLHPLAVEDAVHAHQRPKLERYDDTLF
HHHHHEEECCCCEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHCCHHH
LVLKTVNYVPHESVVLARQIVETGEVMIFVGKNFVVTVRHGEHGELSEVRKRMDTDPEHL
HHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCHHHHHHHHCCCHHHH
RLGSYAVMHAISDYVVDRYLAVTNLMEGDIDAIEEVAFAPGRKLNVEPIYLLKREVIELR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
RCVAPLSAALQRMQTDNKDLISKELRRYLRDVADHQTEAADQIASYDDMLNSLVQAALAR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGMQQNNDMRKMAAWAGIVAMPTMVAAIYGMNFRFMPELNWTWSYPLVMAGMTIVCLVLY
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHH
WQFRNRNWL
HHHCCCCCC
>Mature Secondary Structure
MFPGFDPLPEALRPVTKPRLYTPHVHPIFPPLTEPLVDCGVYVGGHRLPDKYTTYTAALS
CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
RVREIELMGNEGFVWIGLHEPEASHMHNVADVFGLHPLAVEDAVHAHQRPKLERYDDTLF
HHHHHEEECCCCEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHCCHHH
LVLKTVNYVPHESVVLARQIVETGEVMIFVGKNFVVTVRHGEHGELSEVRKRMDTDPEHL
HHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCHHHHHHHHCCCHHHH
RLGSYAVMHAISDYVVDRYLAVTNLMEGDIDAIEEVAFAPGRKLNVEPIYLLKREVIELR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
RCVAPLSAALQRMQTDNKDLISKELRRYLRDVADHQTEAADQIASYDDMLNSLVQAALAR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGMQQNNDMRKMAAWAGIVAMPTMVAAIYGMNFRFMPELNWTWSYPLVMAGMTIVCLVLY
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHH
WQFRNRNWL
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]