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The map label for this gene is mrp

Identifier: 221230007

GI number: 221230007

Start: 1243795

End: 1244946

Strand: Reverse

Name: mrp

Synonym: MLBr_01080

Alternate gene names: 221230007

Gene position: 1244946-1243795 (Counterclockwise)

Preceding gene: 221230012

Following gene: 221230002

Centisome position: 38.09

GC content: 60.42

Gene sequence:

>1152_bases
ATGTCTAGAACTGATCGTAACGCTGCCGACCTGAAATCGGCGGTCAGCACAGCGCTGGCAAAAGTGATCGACCCCGAACT
ACAGCGCCCCATCACTGAACTCGGGATGGTCAAAAACATCGACATCGAGCCGGGTGGCAACGTACAGGTAGGGATTTACC
TGACCATCGCTAGCTGCCCGAAAAAATCCGAAATCAGTAAACGCGTCACCAAGGCTATTGCTGACGTTCCCGGCACCGCG
GCAGTGGAGGTCAGTCTGGACGTGATGAGCGACGAGCAGCGCACCAAGTTGCGCAAAAAGTTACGCGGTGATGCCCGTGA
ACCGATGATCCCGTTCGCTCAACCCAACTCGCTGACCCGAGTGTATACAGTGGCATCCGGCAAGGGAGGAGTCGGAAAGT
CCACCGTCACCGTCAACCTAGCCACGGCGATTGCTGCCCGCGGCCTGGCGGTCGGGGTTCTCGACGCCGACATCCACGGC
CACTCCATCCCCCGGATGATGGGTAGCAACCAGCGACCTATACAGCTTGAGTCAATGATTTTACCGCCTATCGTCCACGA
GGTAAAAGTCATCTCGATAGGCCAGTTCACCGAGGGCAACACGCCGGTAATATGGCGCGGGCCAATGCTGCACCGGGCAT
TGCAGCAGTTTCTATCCGACGTGTATTGGGGCGATCTGGACGTGCTGATGCTCGATCTGCCGCCGGGCACCGGCGACATC
GCCATCTCGGTAGCTCAGTTAATCCCGAACGCCGAGATTCTCGTGGTGACCACGCCACAGCTGGCCGCAGCCGAGGTAGC
CGAACGAGCCGGCAGCATCGCCCTACAGACCCGCCAACGTATTGTCGGTGTCGTGGAGAACATGTCGGGACTTATGATGC
CGGACGGCTCAAGACTACAAGTATTTGGCGAAGGCGGAGGCCAACAAGTCGCCGAGCGGCTCTCACGTGCAGTCGGCACC
GACGTGCCGCTGCTGGGTCAGATCCCGCTGGACCCCGCGCTGGTGGCCGCCGGTGATTCGGGTATACCAATCGTGTTGAA
CGCGTCCGACTCGCCGGTAGGCAAGGAACTGCTCCGCATCGCCGACGGATTGTCATCGCGGCAGCGCAGACTGGCAGGGG
TGTCACTGGGGCTCGACCCGTCGCGGCGCTAA

Upstream 100 bases:

>100_bases
CCACACTGATCTGCATCGACCCATCGAGCTCGGCGCCCGCTCCGGCCAACTGACTACTCGGCGGGCCGAGCGAACGTCGA
GCCACCTACACTCGGCTGTG

Downstream 100 bases:

>100_bases
CGCTAAGGAGTCGCACTGGCAAGTTCGTCGGCGGTTCACATTCGTCGAAATGTAACTGTTGACTTGTACTTTGTGTGCAT
GTTCTGTTGTGGGGGTGGAG

Product: MRP-family ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSRTDRNAADLKSAVSTALAKVIDPELQRPITELGMVKNIDIEPGGNVQVGIYLTIASCPKKSEISKRVTKAIADVPGTA
AVEVSLDVMSDEQRTKLRKKLRGDAREPMIPFAQPNSLTRVYTVASGKGGVGKSTVTVNLATAIAARGLAVGVLDADIHG
HSIPRMMGSNQRPIQLESMILPPIVHEVKVISIGQFTEGNTPVIWRGPMLHRALQQFLSDVYWGDLDVLMLDLPPGTGDI
AISVAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLMMPDGSRLQVFGEGGGQQVAERLSRAVGT
DVPLLGQIPLDPALVAAGDSGIPIVLNASDSPVGKELLRIADGLSSRQRRLAGVSLGLDPSRR

Sequences:

>Translated_383_residues
MSRTDRNAADLKSAVSTALAKVIDPELQRPITELGMVKNIDIEPGGNVQVGIYLTIASCPKKSEISKRVTKAIADVPGTA
AVEVSLDVMSDEQRTKLRKKLRGDAREPMIPFAQPNSLTRVYTVASGKGGVGKSTVTVNLATAIAARGLAVGVLDADIHG
HSIPRMMGSNQRPIQLESMILPPIVHEVKVISIGQFTEGNTPVIWRGPMLHRALQQFLSDVYWGDLDVLMLDLPPGTGDI
AISVAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLMMPDGSRLQVFGEGGGQQVAERLSRAVGT
DVPLLGQIPLDPALVAAGDSGIPIVLNASDSPVGKELLRIADGLSSRQRRLAGVSLGLDPSRR
>Mature_382_residues
SRTDRNAADLKSAVSTALAKVIDPELQRPITELGMVKNIDIEPGGNVQVGIYLTIASCPKKSEISKRVTKAIADVPGTAA
VEVSLDVMSDEQRTKLRKKLRGDAREPMIPFAQPNSLTRVYTVASGKGGVGKSTVTVNLATAIAARGLAVGVLDADIHGH
SIPRMMGSNQRPIQLESMILPPIVHEVKVISIGQFTEGNTPVIWRGPMLHRALQQFLSDVYWGDLDVLMLDLPPGTGDIA
ISVAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLMMPDGSRLQVFGEGGGQQVAERLSRAVGTD
VPLLGQIPLDPALVAAGDSGIPIVLNASDSPVGKELLRIADGLSSRQRRLAGVSLGLDPSRR

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family

Homologues:

Organism=Homo sapiens, GI6912540, Length=261, Percent_Identity=37.5478927203065, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI157384956, Length=257, Percent_Identity=38.9105058365759, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI118572611, Length=239, Percent_Identity=36.8200836820084, Blast_Score=140, Evalue=1e-33,
Organism=Escherichia coli, GI87082045, Length=360, Percent_Identity=34.1666666666667, Blast_Score=168, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI25143050, Length=255, Percent_Identity=35.6862745098039, Blast_Score=137, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6322188, Length=276, Percent_Identity=34.7826086956522, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6321347, Length=271, Percent_Identity=33.9483394833948, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI221511043, Length=247, Percent_Identity=36.8421052631579, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24667611, Length=260, Percent_Identity=35, Blast_Score=141, Evalue=9e-34,
Organism=Drosophila melanogaster, GI19921440, Length=233, Percent_Identity=39.9141630901288, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRP_MYCLE (P53382)

Other databases:

- EMBL:   U15180
- EMBL:   AL583920
- PIR:   B87044
- PIR:   T45199
- RefSeq:   NP_301793.1
- ProteinModelPortal:   P53382
- EnsemblBacteria:   EBMYCT00000029090
- GeneID:   910166
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML1080
- NMPDR:   fig|272631.1.peg.665
- Leproma:   ML1080
- GeneTree:   EBGT00050000015346
- HOGENOM:   HBG586485
- OMA:   MIMPPQA
- ProtClustDB:   CLSK2517957
- BioCyc:   MLEP272631:ML1080-MONOMER
- InterPro:   IPR019591
- InterPro:   IPR015223
- InterPro:   IPR002744
- InterPro:   IPR000808

Pfam domain/function: PF01883 DUF59; PF09140 MipZ; PF10609 ParA

EC number: NA

Molecular weight: Translated: 40545; Mature: 40413

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTDRNAADLKSAVSTALAKVIDPELQRPITELGMVKNIDIEPGGNVQVGIYLTIASCP
CCCCCCCHHHHHHHHHHHHHHHHCHHHHCCHHHHCCEEEECCCCCCCEEEEEEEEEECCC
KKSEISKRVTKAIADVPGTAAVEVSLDVMSDEQRTKLRKKLRGDAREPMIPFAQPNSLTR
CHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEE
VYTVASGKGGVGKSTVTVNLATAIAARGLAVGVLDADIHGHSIPRMMGSNQRPIQLESMI
EEEEECCCCCCCCCEEEEEHHHHHHHCCEEEEEEECCCCCCCCHHHHCCCCCCEEECCCC
LPPIVHEVKVISIGQFTEGNTPVIWRGPMLHRALQQFLSDVYWGDLDVLMLDLPPGTGDI
CCHHHHCEEEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHH
AISVAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLMMPDGSRLQ
EEEHHHHCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCEEE
VFGEGGGQQVAERLSRAVGTDVPLLGQIPLDPALVAAGDSGIPIVLNASDSPVGKELLRI
EEECCCHHHHHHHHHHHHCCCCCEEECCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHH
ADGLSSRQRRLAGVSLGLDPSRR
HHCCCHHHHHHHHEEECCCCCCC
>Mature Secondary Structure 
SRTDRNAADLKSAVSTALAKVIDPELQRPITELGMVKNIDIEPGGNVQVGIYLTIASCP
CCCCCCHHHHHHHHHHHHHHHHCHHHHCCHHHHCCEEEECCCCCCCEEEEEEEEEECCC
KKSEISKRVTKAIADVPGTAAVEVSLDVMSDEQRTKLRKKLRGDAREPMIPFAQPNSLTR
CHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEE
VYTVASGKGGVGKSTVTVNLATAIAARGLAVGVLDADIHGHSIPRMMGSNQRPIQLESMI
EEEEECCCCCCCCCEEEEEHHHHHHHCCEEEEEEECCCCCCCCHHHHCCCCCCEEECCCC
LPPIVHEVKVISIGQFTEGNTPVIWRGPMLHRALQQFLSDVYWGDLDVLMLDLPPGTGDI
CCHHHHCEEEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHH
AISVAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLMMPDGSRLQ
EEEHHHHCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCEEE
VFGEGGGQQVAERLSRAVGTDVPLLGQIPLDPALVAAGDSGIPIVLNASDSPVGKELLRI
EEECCCHHHHHHHHHHHHCCCCCEEECCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHH
ADGLSSRQRRLAGVSLGLDPSRR
HHCCCHHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002